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Dextromethorphan hydrobromide 1 MG/ML / guaifenesin 20 MG/ML / phenylephrine hydrochloride... — RxCUI 1043543

Name: Dextromethorphan hydrobromide 1 MG/ML / guaifenesin 20 MG/ML / phenylephrine hydrochl… (RxCUI 1043543)
Creator: Brian Staiger, PharmD

RxNorm drug concept · Semantic clinical drug

RxCUI 1043543 Semantic clinical drug · SCD ● Current RxNorm concept 71 FDA products 73 package NDCs Snapshot Jul 14, 2026

This page is curated, coded, and maintained by Dr. Brian Staiger, PharmD

Compiled from public NLM RxNorm and FDA (openFDA NDC directory) data sources. Editorial policy

What you’re looking at: the standardized identity of one medicine, as the U.S. drug-data system sees it. Below — every FDA-listed product, package code, price benchmark, and billing code that maps to it.

🗂️ Key Facts

RxCUI1043543

Official nameDextromethorphan hydrobromide 1 MG/ML / guaifenesin 20 MG/ML / phenylephrine hydrochloride 0.5 MG/ML Oral Solution

Concept typeSemantic clinical drug (SCD)

RxNorm statusCurrent RxNorm concept

Also known asdextromethorphan HBr 5 MG / guaifenesin 100 MG / phenylephrine HCl 2.5 MG per 5 ML Oral Solution; dextromethorphan HBr 5 MG / guaiFENesin 100 MG / phenylephrine HCl 2.5 MG in 5 mL Oral Solution; dextromethorphan HBr 20 MG / guaifenesin 400 MG / phenylephrine HCl 10 MG per 20 ML Oral Solution

FDA products mapped71

Package NDCs mapped73

Reported Medicaid activity (SDUD)165 prescriptions · 2 state & territory Medicaid programs · latest period Q4 2025

RxNorm release07/06/2026

Snapshot dataJul 14, 2026

📖 Skip the Codes — Read It in Plain English.

Our pharmacist-built guide to Phenylephrine: what it is, how it’s used, side effects, and interactions.

📗 Our plain-language guide HelloPharmacist

Yes, it's the same active ingredient, but used in very different ways depending on the form. The nasal spray delivers a tiny amount directly to the nasal lining to temporarily shri...
I see phenylephrine in nasal sprays at the pharmacy AND as an IV drug in the hospital — is it really the same medication?
You should check with your doctor first. Phenylephrine constricts blood vessels, which can raise blood pressure and put extra strain on the heart — even from a nasal spray. If you...
Can I use the nasal spray if I have high blood pressure or heart disease?

📖 Read our full Phenylephrine guide →

🕸️ Concept Web — How Dextromethorphan hydrobromide 1 MG/ML / guaifene... Connects

One RxCUI never lives alone. Follow the path from the raw ingredient down to the exact strength-and-form concepts FDA products carry — every stop is a real RxNorm concept with its own identifier. Hover or focus any chip for what it means.

This page's concept Dextromethorphan hydrobromide 1 MG/ML / guaifenesin 20 MG/ML / phenylephrine hydrochloride 0.5 MG/ML Oral Solution RxCUI 1043543 Semantic clinical drug · SCD

Every web starts here: one RxCUI, one fixed meaning in the RxNorm vocabulary.

Ingredients 6

The active substance itself — no strength, form, or brand attached yet.
- Dextromethorphan 3289 IN
- Guaifenesin 5032 IN
- Phenylephrine 8163 IN
- Dextromethorphan / guaifenesin / phenylephrine 214494 MIN
- Dextromethorphan hydrobromide 102490 PIN
- Phenylephrine hydrochloride 8164 PIN
Dose forms 9

The ingredient poured into a form — tablet, solution, cream — still without one fixed strength.
- Dextromethorphan / guaifenesin / phenylephrine Oral Solution 375427 SCDF
- Dextromethorphan hydrobromide / guaifenesin / phenylephrine hydrochloride Oral Solution 2645876 SCDFP
- Dextromethorphan / guaifenesin / phenylephrine Oral Liquid Product 1154857 SCDG
- Dextromethorphan / guaifenesin / phenylephrine Oral Product 1154858 SCDG
- Dextromethorphan hydrobromide / guaifenesin / phenylephrine hydrochloride Oral Liquid Product 2663136 SCDGP
- Dextromethorphan hydrobromide / guaifenesin / phenylephrine hydrochloride Oral Product 2663549 SCDGP
- Oral Solution 316968 DF
- Oral Liquid Product 1151137 DFG
- +1 more in this family
Clinical & branded drugs 3

Ingredient + strength + dose form. These are the concepts real FDA products actually carry.
- Dextromethorphan hydrobromide 1 MG/ML 1020137 SCDC
- Guaifenesin 20 MG/ML 316011 SCDC
- Phenylephrine hydrochloride 0.5 MG/ML 707273 SCDC
Packs 3

Fixed collections of drugs packaged and sold together, like dose packs.
- {1 (acetaminophen 32.5 MG/ML / dextromethorphan hydrobromide 1 MG/ML / phenylephrine hydrochloride 0.5 MG/ML / triprolidine hydrochloride 0.125 MG/ML Oral Solution) / 1 (dextromethorphan hydrobromide 1 MG/ML / guaifenesin 20 MG/ML / phenylephrine hydrochloride 0.5 MG/ML Oral Solution) } Pack 2288826 GPCK
- {1 (acetaminophen 32.5 MG/ML / dextromethorphan hydrobromide 1 MG/ML / triprolidine hydrochloride 0.125 MG/ML Oral Solution) / 1 (dextromethorphan hydrobromide 1 MG/ML / guaifenesin 20 MG/ML / phenylephrine hydrochloride 0.5 MG/ML Oral Solution) } Pack 2390630 GPCK
- {1 (acetaminophen 32.5 MG/ML / diphenhydramine hydrochloride 1.25 MG/ML / phenylephrine hydrochloride 0.5 MG/ML Oral Solution) / 1 (dextromethorphan hydrobromide 1 MG/ML / guaifenesin 20 MG/ML / phenylephrine hydrochloride 0.5 MG/ML Oral Solution) } Pack 2637728 GPCK

Showing up to 8 concepts per family — 20 of 21 stored related concepts drawn.

These are official RxNorm vocabulary relationships — how concepts name and organize the same medicine. They do not establish therapeutic equivalence or substitutability: two concepts appearing in one web is never a statement that products can be swapped.

🔀 Generic ⇄ Brand Crosswalk

The same medicine has an unbranded (generic) identity and one or more brand-name identities — each with its own RxCUI. This is a naming relationship in RxNorm, not a statement that any two products are substitutable.

Generic (Clinical) Concepts

{1 (acetaminophen 32.5 MG/ML / dextromethorphan hydrobromide 1 MG/ML / triprolidine hydrochloride 0.125 MG/ML Oral Solution) / 1 (dextromethorphan hydrobromide 1 MG/ML / guaifenesin 20 MG/ML / phenylephrine hydrochloride 0.5 MG/ML Oral Solution) } Pack GPCK · 2390630
{1 (acetaminophen 32.5 MG/ML / diphenhydramine hydrochloride 1.25 MG/ML / phenylephrine hydrochloride 0.5 MG/ML Oral Solution) / 1 (dextromethorphan hydrobromide 1 MG/ML / guaifenesin 20 MG/ML / phenylephrine hydrochloride 0.5 MG/ML Oral Solution) } Pack GPCK · 2637728
Dextromethorphan hydrobromide 1 MG/ML SCDC · 1020137
Guaifenesin 20 MG/ML SCDC · 316011
Phenylephrine hydrochloride 0.5 MG/ML SCDC · 707273
Dextromethorphan / guaifenesin / phenylephrine Oral Solution SCDF · 375427
Dextromethorphan hydrobromide / guaifenesin / phenylephrine hydrochloride Oral Solution SCDFP · 2645876
Dextromethorphan / guaifenesin / phenylephrine Oral Liquid Product SCDG · 1154857
Dextromethorphan / guaifenesin / phenylephrine Oral Product SCDG · 1154858
Dextromethorphan hydrobromide / guaifenesin / phenylephrine hydrochloride Oral Liquid Product SCDGP · 2663136

📦 FDA Products & Package NDCs

71 products · 73 package NDCs

73 package NDCs map to RxCUI 1043543 in the current snapshot — up to 50 per page. Each linked NDC opens its full package page.

Package NDC	Package	Brand / generic name	Labeler	Marketing start
63824-0955-74	1 KIT in 1 CARTON (63824-955-74) * 118 mL in 1 BOTTLE * 1...	Mucinex Childrens Day Time Multi-Symptom Cold and Night Time Multi-Symptom Cold	Reckitt Benckiser LLC	2019-01-21
63824-0956-64	1 BOTTLE in 1 CARTON (63824-956-64) / 118 mL in 1 BOTTLE	Mucinex Childrens FreeFrom Multi-Symptom Cold and Stuffy Nose	Reckitt Benckiser LLC	2020-06-01
63868-0745-06	177 mL in 1 BOTTLE, PLASTIC (63868-745-06)	Mucus Relief Severe Congestion and Cough Maximum Strength	QUALITY CHOICE (Chain Drug Marketing Association)	2015-01-31
63941-0517-25	177 mL in 1 BOTTLE (63941-517-25)	Severe Congestion and Cough Max	Best Choice	2025-01-01
68163-0738-09	266 mL in 1 BOTTLE, PLASTIC (68163-738-09)	Mucus Relief Severe Congestion and Cough Maximum Strength	Raritan Pharmaceuticals Inc	2019-02-05
69256-0337-06	177 mL in 1 BOTTLE, PLASTIC (69256-337-06)	Mucus Relief Severe Congestion and Cough Maximum Strength	Harris Teeter, LLC	2021-05-28
69842-0462-12	1 KIT in 1 KIT (69842-462-12) * 177 mL in 1 BOTTLE, PLASTI...	Daytime Mucus Relief Severe Congestion and Cough and Nighttime Cold and Flu Maximum Strength	CVS Pharmacy	2018-04-30
69842-0570-88	1 BOTTLE, PLASTIC in 1 CARTON (69842-570-88) / 201 mL in 1...	Cold Childrens, Multi Symptom	CVS PHARMACY	2018-07-31
69842-0756-88	1 BOTTLE, PLASTIC in 1 CARTON (69842-756-88) / 201 mL in 1...	Congestion and Cough Childrens	CVS PHARMACY	2018-07-01
69842-0767-06	180 mL in 1 BOTTLE, PLASTIC (69842-767-06)	CVS Maximum Strength Severe Congestion and Cough	CVS PHARMACY, INC	2020-03-31
69842-0820-08	1 KIT in 1 KIT (69842-820-08) * 118 mL in 1 BOTTLE, PLASTI...	Multi Symptom Cold and Multi Symptom Nighttime Cold Childrens	CVS Pharmacy	2017-02-28
69842-0942-45	177 mL in 1 BOTTLE, PLASTIC (69842-942-45)	Severe Cough and Congestion	CVS PHARMACY	2020-11-17
70000-0629-01	1 BOTTLE in 1 CARTON (70000-0629-1) / 118 mL in 1 BOTTLE	Leader Childrens Multi Symptom Cold	CARDINAL HEALTH 110, LLC. DBA LEADER	2023-03-15
72288-0649-04	1 BOTTLE in 1 CARTON (72288-649-04) / 118 mL in 1 BOTTLE	AMAZON Childrens Multi Symptom Cold	AMAZON.COM SERVICES LLC	2026-02-16
72854-0166-26	1 KIT in 1 CARTON (72854-166-26) * 180 mL in 1 BOTTLE (638...	Mucinex Fast-Max Severe Congestion and Cough and Mucinex Nighttime Cold and Flu	Reckitt Benckiser LLC	2025-06-01
76162-0040-45	177 mL in 1 BOTTLE, PLASTIC (76162-040-45)	Mucus Relief Severe Congestion and Cough	TOPCO ASSOCIATES LLC	2023-08-10
76162-0057-88	1 BOTTLE, PLASTIC in 1 CARTON (76162-057-88) / 201 mL in 1...	Mucus Relief Childrens	TOPCO ASSOCIATES LLC	2024-03-07
76281-0517-25	177 mL in 1 BOTTLE (76281-517-25)	SEVERE CONGESTION and COUGH MAX	AptaPharma Inc.	2024-01-30
79903-0176-06	1 BOTTLE, PLASTIC in 1 CARTON (79903-176-06) / 201 mL in 1...	Multi-Symptom Cold childrens	WALMART INC.	2023-06-09
79903-0270-03	1 BOTTLE in 1 CARTON (79903-270-03) / 118 mL in 1 BOTTLE	Childrens Multi-symptom Cold Daytime	Wal-Mart Stores, Inc.	2024-11-14
82442-0476-08	1 KIT in 1 CARTON (82442-476-08) * 118 mL in 1 BOTTLE (824...	up and up Daytime Nighttime Childrens Multi Symptom Cold	Target Corporation	2024-07-19
83324-0077-06	177 mL in 1 BOTTLE, PLASTIC (83324-077-06)	Mucus Relief Severe Congestion and Cough	Chain Drug Marketing Association, Inc.	2025-09-15
83324-0144-06	177 mL in 1 BOTTLE (83324-144-06)	QCH Maximum Strength Mucus Relief 617	Chain Drug Marketing Association Inc.	2024-09-06

Observed labelers: Reckitt Benckiser LLC (9) · Walgreens (6) · CVS PHARMACY (5) · Walgreen Company (5) · TARGET Corporation (4) · Dolgencorp, Inc. (DOLLAR GENERAL & REXALL) (3) · +34 more — this is the FDA-listed mapping footprint, not sales, inventory, availability, or market share.

🗃️ Sources & Limits

Atlas generation902fddb9-e9c1-4004-bf4c-dba4d51037c7

openFDA export observedJul 14, 2026

RxNorm release07/06/2026

Methodology2026-07-full-catalog-v1

A shared RxCUI does not prove interchangeability. Products mapped to the same concept are not thereby equivalent or substitutable — equivalence is a separate, product-level determination.
Listing here does not establish approval or coverage. Appearing in this snapshot is a data observation, not an FDA approval status or a payer coverage decision.
Missing data never means zero. A silent dataset (no price, no billing code, no utilization) means no observation — not that the real-world value is zero.
Counts describe the mapping footprint. Product, package, and labeler counts are the FDA-listed mapping footprint in this snapshot — not sales, inventory, availability, or market share.

This product uses publicly available data from the U.S. National Library of Medicine (NLM), National Institutes of Health, Department of Health and Human Services; NLM is not responsible for the product and does not endorse or recommend this or any other product.

Machine-readable JSON

Reference information about drug-concept identifiers and public regulatory data — not medical advice. Talk to your pharmacist or prescriber about your own medication.