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{1 (acetaminophen 32.5 MG/ML / diphenhydramine hydrochloride 1.25 MG/ML / phenylephrine hy... — RxCUI 2637728

Name: {1 (acetaminophen 32.5 MG/ML / diphenhydramine hydrochloride 1.25 MG/ML / phenylephri… (RxCUI 2637728)
Creator: Brian Staiger, PharmD

RxNorm drug concept · Generic pack

RxCUI 2637728 Generic pack · GPCK ● Current RxNorm concept 11 FDA products 11 package NDCs Snapshot Jul 14, 2026

This page is curated, coded, and maintained by Dr. Brian Staiger, PharmD

Compiled from public NLM RxNorm and FDA (openFDA NDC directory) data sources. Editorial policy

What you’re looking at: the standardized identity of one medicine, as the U.S. drug-data system sees it. Below — every FDA-listed product, package code, price benchmark, and billing code that maps to it.

🗂️ Key Facts

RxCUI2637728

Official name{1 (acetaminophen 32.5 MG/ML / diphenhydramine hydrochloride 1.25 MG/ML / phenylephrine hydrochloride 0.5 MG/ML Oral Solution) / 1 (dextromethorphan hydrobromide 1 MG/ML / guaifenesin 20 MG/ML / phenylephrine hydrochloride 0.5 MG/ML Oral Solution) } Pack

Concept typeGeneric pack (GPCK)

RxNorm statusCurrent RxNorm concept

Also known as1 daytime (dextromethorphan HBr 5 MG / guaifenesin 100 MG / phenylephrine HCl 2.5 MG per 5 ML Oral Solution) / 1 nighttime (acetaminophen 325 MG / diphenhydramine HCl 12.5 MG / phenylephrine HCl 5 MG per 10 ML Oral Solution) Pack; 1 daytime (dextromethorphan HBr 5 MG / guaiFENesin 100 MG / phenylephrine HCl 2.5 MG in 5 mL Oral Solution) / 1 nighttime (acetaminophen 325 MG / diphenhydrAMINE HCl 12.5 MG / phenylephrine HCl 5 MG in 10 mL Oral Solution) Pack

FDA products mapped11

Package NDCs mapped11

RxNorm release07/06/2026

Snapshot dataJul 14, 2026

📖 Skip the Codes — Read It in Plain English.

Our pharmacist-built guide to Diphenhydramine Topical: what it is, how it’s used, side effects, and interactions.

📗 Our plain-language guide HelloPharmacist

You can use it for temporary relief of pain and itching from everyday skin problems — things like insect bites, minor burns, minor cuts and scrapes, and general skin irritations. I...
What can I actually use this cream or spray for?
You can apply it up to 3 to 4 times a day, but no more than that. More frequent use isn't going to help more — and the label is clear that you shouldn't exceed that limit. For kids...
This is really important — do not use this topical product at the same time as any other product that contains diphenhydramine, even a pill or capsule. That includes allergy medici...

📖 Read our full Diphenhydramine Topical guide →

🕸️ Concept Web — How {1 (acetaminophen 32.5 MG/ML / diphenhydramine h... Connects

One RxCUI never lives alone. Follow the path from the raw ingredient down to the exact strength-and-form concepts FDA products carry — every stop is a real RxNorm concept with its own identifier. Hover or focus any chip for what it means.

This page's concept {1 (acetaminophen 32.5 MG/ML / diphenhydramine hydrochloride 1.25 MG/ML / phenylephrine hydrochloride 0.5 MG/ML Oral Solution) / 1 (dextromethorphan hydrobromide 1 MG/ML / guaifenesin 20 MG/ML / phenylephrine hydrochloride 0.5 MG/ML Oral Solution) } Pack RxCUI 2637728 Generic pack · GPCK

Every web starts here: one RxCUI, one fixed meaning in the RxNorm vocabulary.

Ingredients 10

The active substance itself — no strength, form, or brand attached yet.
- Acetaminophen 161 IN
- Dextromethorphan 3289 IN
- Diphenhydramine 3498 IN
- Guaifenesin 5032 IN
- Phenylephrine 8163 IN
- Acetaminophen / diphenhydramine / phenylephrine 689785 MIN
- Dextromethorphan / guaifenesin / phenylephrine 214494 MIN
- Dextromethorphan hydrobromide 102490 PIN
- +2 more in this family
Dose forms 15

The ingredient poured into a form — tablet, solution, cream — still without one fixed strength.
- Acetaminophen / diphenhydramine / phenylephrine Oral Solution 705813 SCDF
- Dextromethorphan / guaifenesin / phenylephrine Oral Solution 375427 SCDF
- Acetaminophen / diphenhydramine hydrochloride / phenylephrine hydrochloride Oral Solution 2645883 SCDFP
- Dextromethorphan hydrobromide / guaifenesin / phenylephrine hydrochloride Oral Solution 2645876 SCDFP
- Acetaminophen / diphenhydramine / phenylephrine Oral Liquid Product 1151195 SCDG
- Acetaminophen / diphenhydramine / phenylephrine Oral Product 1151196 SCDG
- Dextromethorphan / guaifenesin / phenylephrine Oral Liquid Product 1154857 SCDG
- Dextromethorphan / guaifenesin / phenylephrine Oral Product 1154858 SCDG
- +7 more in this family
Clinical & branded drugs 7

Ingredient + strength + dose form. These are the concepts real FDA products actually carry.
- Acetaminophen 32.5 MG/ML / diphenhydramine hydrochloride 1.25 MG/ML / phenylephrine hydrochloride 0.5 MG/ML Oral Solution 1375932 SCD
- Dextromethorphan hydrobromide 1 MG/ML / guaifenesin 20 MG/ML / phenylephrine hydrochloride 0.5 MG/ML Oral Solution 1043543 SCD
- Acetaminophen 32.5 MG/ML 336021 SCDC
- Dextromethorphan hydrobromide 1 MG/ML 1020137 SCDC
- Diphenhydramine hydrochloride 1.25 MG/ML 1049883 SCDC
- Guaifenesin 20 MG/ML 316011 SCDC
- Phenylephrine hydrochloride 0.5 MG/ML 707273 SCDC

Showing up to 8 concepts per family — 23 of 32 stored related concepts drawn.

These are official RxNorm vocabulary relationships — how concepts name and organize the same medicine. They do not establish therapeutic equivalence or substitutability: two concepts appearing in one web is never a statement that products can be swapped.

🔀 Generic ⇄ Brand Crosswalk

The same medicine has an unbranded (generic) identity and one or more brand-name identities — each with its own RxCUI. This is a naming relationship in RxNorm, not a statement that any two products are substitutable.

Generic (Clinical) Concepts

Acetaminophen 32.5 MG/ML / diphenhydramine hydrochloride 1.25 MG/ML / phenylephrine hydrochloride 0.5 MG/ML Oral Solution SCD · 1375932
Dextromethorphan hydrobromide 1 MG/ML / guaifenesin 20 MG/ML / phenylephrine hydrochloride 0.5 MG/ML Oral Solution SCD · 1043543
Acetaminophen 32.5 MG/ML SCDC · 336021
Dextromethorphan hydrobromide 1 MG/ML SCDC · 1020137
Diphenhydramine hydrochloride 1.25 MG/ML SCDC · 1049883
Guaifenesin 20 MG/ML SCDC · 316011
Phenylephrine hydrochloride 0.5 MG/ML SCDC · 707273
Acetaminophen / diphenhydramine / phenylephrine Oral Solution SCDF · 705813
Dextromethorphan / guaifenesin / phenylephrine Oral Solution SCDF · 375427
Acetaminophen / diphenhydramine hydrochloride / phenylephrine hydrochloride Oral Solution SCDFP · 2645883

📦 FDA Products & Package NDCs

11 products · 11 package NDCs

11 package NDCs map to RxCUI 2637728 in the current snapshot — up to 50 per page. Each linked NDC opens its full package page.

Package NDC	Package	Brand / generic name	Labeler	Marketing start
00363-0862-12	1 KIT in 1 KIT (0363-0862-12) * 177 mL in 1 BOTTLE, PLASTI...	Daytime Mucus Relief Severe Congestion and Cough and Nighttime Cold and Flu Maximum Strength	Walgreens	2015-07-31
00363-4200-08	1 KIT in 1 KIT (0363-4200-08) * 118 mL in 1 BOTTLE, PLASTI...	Daytime Nighttime Multi Symptom Cold Childrens	Walgreens	2014-12-31
11673-0420-08	1 KIT in 1 KIT (11673-420-08) * 118 mL in 1 BOTTLE, PLASTI...	Multi Symptom Cold and Multi Symptom Nighttime Cold Childrens	TARGET Corporation	2017-02-28
49035-0938-04	1 KIT in 1 KIT (49035-938-04) * 1 BOTTLE in 1 CARTON / 118...	Daytime Nighttime Childrens Multi-symptom Cold	Wal-Mart Stores, Inc.	2024-11-26
55910-0562-12	1 KIT in 1 KIT (55910-562-12) * 177 mL in 1 BOTTLE, PLASTI...	Mucus Relief Severe Congestion Cough Night Time Cold and Flu Maximum Strength	Dolgencorp, Inc. (DOLLAR GENERAL & REXALL)	2018-03-31
63824-0287-22	1 KIT in 1 CARTON (63824-287-22) * 118 mL in 1 BOTTLE * 1...	Childrens Mucinex Multi Symptom Cold and Childrens Mucinex Night Time Multi Symptom Cold	Reckitt Benckiser LLC	2014-04-01
63824-0944-34	1 KIT in 1 CARTON (63824-944-34) * 1 BOTTLE in 1 CARTON (6...	Mucinex Childrens Day Time Multi-Symptom Cold and Mucinex Childrens Night Time Multi-Symptom Cold Triple Pack	Reckitt Benckiser LLC	2022-05-25
63824-0955-74	1 KIT in 1 CARTON (63824-955-74) * 118 mL in 1 BOTTLE * 1...	Mucinex Childrens Day Time Multi-Symptom Cold and Night Time Multi-Symptom Cold	Reckitt Benckiser LLC	2019-01-21
69842-0462-12	1 KIT in 1 KIT (69842-462-12) * 177 mL in 1 BOTTLE, PLASTI...	Daytime Mucus Relief Severe Congestion and Cough and Nighttime Cold and Flu Maximum Strength	CVS Pharmacy	2018-04-30
69842-0820-08	1 KIT in 1 KIT (69842-820-08) * 118 mL in 1 BOTTLE, PLASTI...	Multi Symptom Cold and Multi Symptom Nighttime Cold Childrens	CVS Pharmacy	2017-02-28
82442-0476-08	1 KIT in 1 CARTON (82442-476-08) * 118 mL in 1 BOTTLE (824...	up and up Daytime Nighttime Childrens Multi Symptom Cold	Target Corporation	2024-07-19

Observed labelers: Reckitt Benckiser LLC (3) · CVS Pharmacy (2) · TARGET Corporation (2) · Walgreens (2) · Dolgencorp, Inc. (DOLLAR GENERAL & REXALL) (1) · Wal-Mart Stores, Inc. (1) — this is the FDA-listed mapping footprint, not sales, inventory, availability, or market share.

🗃️ Sources & Limits

Atlas generation902fddb9-e9c1-4004-bf4c-dba4d51037c7

openFDA export observedJul 14, 2026

RxNorm release07/06/2026

Methodology2026-07-full-catalog-v1

A shared RxCUI does not prove interchangeability. Products mapped to the same concept are not thereby equivalent or substitutable — equivalence is a separate, product-level determination.
Listing here does not establish approval or coverage. Appearing in this snapshot is a data observation, not an FDA approval status or a payer coverage decision.
Missing data never means zero. A silent dataset (no price, no billing code, no utilization) means no observation — not that the real-world value is zero.
Counts describe the mapping footprint. Product, package, and labeler counts are the FDA-listed mapping footprint in this snapshot — not sales, inventory, availability, or market share.

This product uses publicly available data from the U.S. National Library of Medicine (NLM), National Institutes of Health, Department of Health and Human Services; NLM is not responsible for the product and does not endorse or recommend this or any other product.

Machine-readable JSON

Reference information about drug-concept identifiers and public regulatory data — not medical advice. Talk to your pharmacist or prescriber about your own medication.