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Acetaminophen 32.5 MG/ML / diphenhydramine hydrochloride 1.25 MG/ML / phenylephrine hydroc... — RxCUI 1375932

Name: Acetaminophen 32.5 MG/ML / diphenhydramine hydrochloride 1.25 MG/ML / phenylephrine h… (RxCUI 1375932)
Creator: Brian Staiger, PharmD

RxNorm drug concept · Semantic clinical drug

RxCUI 1375932 Semantic clinical drug · SCD ● Current RxNorm concept 24 FDA products 25 package NDCs Snapshot Jul 14, 2026

This page is curated, coded, and maintained by Dr. Brian Staiger, PharmD

Compiled from public NLM RxNorm and FDA (openFDA NDC directory) data sources. Editorial policy

What you’re looking at: the standardized identity of one medicine, as the U.S. drug-data system sees it. Below — every FDA-listed product, package code, price benchmark, and billing code that maps to it.

🗂️ Key Facts

RxCUI1375932

Official nameAcetaminophen 32.5 MG/ML / diphenhydramine hydrochloride 1.25 MG/ML / phenylephrine hydrochloride 0.5 MG/ML Oral Solution

Concept typeSemantic clinical drug (SCD)

RxNorm statusCurrent RxNorm concept

Also known asacetaminophen 650 MG / diphenhydramine HCl 25 MG / phenylephrine HCl 10 MG per 20 ML Oral Solution; acetaminophen 650 MG / diphenhydrAMINE HCl 25 MG / phenylephrine HCl 10 MG in 20 mL Oral Solution; acetaminophen 325 MG / diphenhydramine HCl 12.5 MG / phenylephrine HCl 5 MG per 10 ML Oral Solution; APAP 32.5 MG/ML / Diphenhydramine Hydrochloride 1.25 MG/ML / Phenylephrine Hydrochloride 0.5 MG/ML Oral Solution; APAP 325 MG / diphenhydramine hydrochloride 12.5 MG / phenylephrine hydrochloride 5 MG per 10 ML Oral Solution +1 more

FDA products mapped24

Package NDCs mapped25

RxNorm release07/06/2026

Snapshot dataJul 14, 2026

📖 Skip the Codes — Read It in Plain English.

Our pharmacist-built guide to Diphenhydramine Topical: what it is, how it’s used, side effects, and interactions.

📗 Our plain-language guide HelloPharmacist

You can use it for temporary relief of pain and itching from everyday skin problems — things like insect bites, minor burns, minor cuts and scrapes, and general skin irritations. I...
What can I actually use this cream or spray for?
You can apply it up to 3 to 4 times a day, but no more than that. More frequent use isn't going to help more — and the label is clear that you shouldn't exceed that limit. For kids...
This is really important — do not use this topical product at the same time as any other product that contains diphenhydramine, even a pill or capsule. That includes allergy medici...

📖 Read our full Diphenhydramine Topical guide →

🕸️ Concept Web — How Acetaminophen 32.5 MG/ML / diphenhydramine hydro... Connects

One RxCUI never lives alone. Follow the path from the raw ingredient down to the exact strength-and-form concepts FDA products carry — every stop is a real RxNorm concept with its own identifier. Hover or focus any chip for what it means.

This page's concept Acetaminophen 32.5 MG/ML / diphenhydramine hydrochloride 1.25 MG/ML / phenylephrine hydrochloride 0.5 MG/ML Oral Solution RxCUI 1375932 Semantic clinical drug · SCD

Every web starts here: one RxCUI, one fixed meaning in the RxNorm vocabulary.

Ingredients 6

The active substance itself — no strength, form, or brand attached yet.
- Acetaminophen 161 IN
- Diphenhydramine 3498 IN
- Phenylephrine 8163 IN
- Acetaminophen / diphenhydramine / phenylephrine 689785 MIN
- Diphenhydramine hydrochloride 1362 PIN
- Phenylephrine hydrochloride 8164 PIN
Dose forms 9

The ingredient poured into a form — tablet, solution, cream — still without one fixed strength.
- Acetaminophen / diphenhydramine / phenylephrine Oral Solution 705813 SCDF
- Acetaminophen / diphenhydramine hydrochloride / phenylephrine hydrochloride Oral Solution 2645883 SCDFP
- Acetaminophen / diphenhydramine / phenylephrine Oral Liquid Product 1151195 SCDG
- Acetaminophen / diphenhydramine / phenylephrine Oral Product 1151196 SCDG
- Acetaminophen / diphenhydramine hydrochloride / phenylephrine hydrochloride Oral Liquid Product 2661848 SCDGP
- Acetaminophen / diphenhydramine hydrochloride / phenylephrine hydrochloride Oral Product 2659765 SCDGP
- Oral Solution 316968 DF
- Oral Liquid Product 1151137 DFG
- +1 more in this family
Clinical & branded drugs 3

Ingredient + strength + dose form. These are the concepts real FDA products actually carry.
- Acetaminophen 32.5 MG/ML 336021 SCDC
- Diphenhydramine hydrochloride 1.25 MG/ML 1049883 SCDC
- Phenylephrine hydrochloride 0.5 MG/ML 707273 SCDC
Packs 3

Fixed collections of drugs packaged and sold together, like dose packs.

Showing up to 8 concepts per family — 20 of 21 stored related concepts drawn.

These are official RxNorm vocabulary relationships — how concepts name and organize the same medicine. They do not establish therapeutic equivalence or substitutability: two concepts appearing in one web is never a statement that products can be swapped.

🔀 Generic ⇄ Brand Crosswalk

The same medicine has an unbranded (generic) identity and one or more brand-name identities — each with its own RxCUI. This is a naming relationship in RxNorm, not a statement that any two products are substitutable.

Generic (Clinical) Concepts

{1 (acetaminophen 32.5 MG/ML / dextromethorphan hydrobromide 1 MG/ML / guaifenesin 20 MG/ML / phenylephrine hydrochloride 0.5 MG/ML Oral Solution) / 1 (acetaminophen 32.5 MG/ML / diphenhydramine hydrochloride 1.25 MG/ML / phenylephrine hydrochloride 0.5 MG/ML Oral Solution) } Pack GPCK · 1424850
{1 (acetaminophen 32.5 MG/ML / diphenhydramine hydrochloride 1.25 MG/ML / phenylephrine hydrochloride 0.5 MG/ML Oral Solution) / 1 (dextromethorphan hydrobromide 1 MG/ML / guaifenesin 20 MG/ML / phenylephrine hydrochloride 0.5 MG/ML Oral Solution) } Pack GPCK · 2637728
{1 (acetaminophen 32.5 MG/ML / diphenhydramine hydrochloride 1.25 MG/ML / phenylephrine hydrochloride 0.5 MG/ML Oral Solution) / 1 (dextromethorphan hydrobromide 1 MG/ML / guaifenesin 20 MG/ML Oral Solution) } Pack GPCK · 2637730
Acetaminophen 32.5 MG/ML SCDC · 336021
Diphenhydramine hydrochloride 1.25 MG/ML SCDC · 1049883
Phenylephrine hydrochloride 0.5 MG/ML SCDC · 707273
Acetaminophen / diphenhydramine / phenylephrine Oral Solution SCDF · 705813
Acetaminophen / diphenhydramine hydrochloride / phenylephrine hydrochloride Oral Solution SCDFP · 2645883
Acetaminophen / diphenhydramine / phenylephrine Oral Liquid Product SCDG · 1151195
Acetaminophen / diphenhydramine / phenylephrine Oral Product SCDG · 1151196

📦 FDA Products & Package NDCs

24 products · 25 package NDCs

25 package NDCs map to RxCUI 1375932 in the current snapshot — up to 50 per page. Each linked NDC opens its full package page.

Package NDC	Package	Brand / generic name	Labeler	Marketing start
00031-8752-12	1 BOTTLE in 1 CARTON (0031-8752-12) / 118 mL in 1 BOTTLE	Robitussin Severe Multi-Symptom Cough Cold Flu Nighttime	Haleon US Holdings LLC	2015-07-01
00031-8752-18	1 BOTTLE in 1 CARTON (0031-8752-18) / 237 mL in 1 BOTTLE	Robitussin Severe Multi-Symptom Cough Cold Flu Nighttime	Haleon US Holdings LLC	2015-07-01
00363-0460-06	177 mL in 1 BOTTLE, PLASTIC (0363-0460-06)	Nighttime Cold and Flu Maximum Strength	Walgreens	2015-06-30
00363-0463-12	1 KIT in 1 KIT (0363-0463-12) * 177 mL in 1 BOTTLE, PLASTI...	DayTime Mucus Relief Severe Cold and Nighttime Cold and Flu Maximum Strength	Walgreens	2016-03-31
00363-0862-12	1 KIT in 1 KIT (0363-0862-12) * 177 mL in 1 BOTTLE, PLASTI...	Daytime Mucus Relief Severe Congestion and Cough and Nighttime Cold and Flu Maximum Strength	Walgreens	2015-07-31
00363-4200-08	1 KIT in 1 KIT (0363-4200-08) * 118 mL in 1 BOTTLE, PLASTI...	Daytime Nighttime Multi Symptom Cold Childrens	Walgreens	2014-12-31
00363-9130-06	177 mL in 1 BOTTLE, PLASTIC (0363-9130-06)	Mucus Relief All in One Maximum Strength	Walgreens	2021-08-27
00363-9140-12	1 KIT in 1 KIT (0363-9140-12) * 177 mL in 1 BOTTLE, PLASTI...	Mucus Relief All In One Daytime Nighttime Cold Flu Maximum Strength	Walgreens	2019-09-30
11673-0420-08	1 KIT in 1 KIT (11673-420-08) * 118 mL in 1 BOTTLE, PLASTI...	Multi Symptom Cold and Multi Symptom Nighttime Cold Childrens	TARGET Corporation	2017-02-28
11673-0794-01	1 KIT in 1 KIT (11673-794-01) * 177 mL in 1 BOTTLE, PLASTI...	Maximum Strength Daytime Severe and Nighttime Cold and Flu	TARGET Corporation	2024-05-01
30142-0736-06	180 mL in 1 BOTTLE (30142-736-06)	Maximum Strength Nighttime Cold and Flu	THE KROGER CO	2020-09-04
49035-0623-03	1 BOTTLE in 1 CARTON (49035-623-03) / 118 mL in 1 BOTTLE	Equate Childrens Multi symptom Cold Nighttime	Wal-Mart Stores, Inc.	2017-08-01
49035-0938-04	1 KIT in 1 KIT (49035-938-04) * 1 BOTTLE in 1 CARTON / 118...	Daytime Nighttime Childrens Multi-symptom Cold	Wal-Mart Stores, Inc.	2024-11-26
51316-0733-04	118 mL in 1 BOTTLE (51316-733-04)	CVS Childrens Nighttime Multi Symptom Cold	CVS PHARMACY	2023-02-20
55910-0460-06	177 mL in 1 BOTTLE, PLASTIC (55910-460-06)	Nighttime Cold and Flu Maximum Strength	Dolgencorp, Inc. (DOLLAR GENERAL & REXALL)	2018-03-31
55910-0562-12	1 KIT in 1 KIT (55910-562-12) * 177 mL in 1 BOTTLE, PLASTI...	Mucus Relief Severe Congestion Cough Night Time Cold and Flu Maximum Strength	Dolgencorp, Inc. (DOLLAR GENERAL & REXALL)	2018-03-31
63824-0212-64	1 BOTTLE in 1 CARTON (63824-212-64) / 118 mL in 1 BOTTLE	Childrens Delsym Cough Plus Cold Night Time	Reckitt Benckiser LLC	2017-06-09
63824-0218-22	1 KIT in 1 CARTON (63824-218-22) * 118 mL in 1 BOTTLE * 1...	Childrens Delsym Cough Plus Chest Congestion DM and Delsym Cough Plus Cold Night Time	Reckitt Benckiser LLC	2017-07-01
63824-0287-22	1 KIT in 1 CARTON (63824-287-22) * 118 mL in 1 BOTTLE * 1...	Childrens Mucinex Multi Symptom Cold and Childrens Mucinex Night Time Multi Symptom Cold	Reckitt Benckiser LLC	2014-04-01
63824-0944-34	1 KIT in 1 CARTON (63824-944-34) * 1 BOTTLE in 1 CARTON (6...	Mucinex Childrens Day Time Multi-Symptom Cold and Mucinex Childrens Night Time Multi-Symptom Cold Triple Pack	Reckitt Benckiser LLC	2022-05-25
63824-0950-21	1 BOTTLE in 1 CARTON (63824-950-21) / 118 mL in 1 BOTTLE	Mucinex Childrens Night Time Multi-Symptom Cold	Reckitt Benckiser LLC	2018-05-01
63824-0955-74	1 KIT in 1 CARTON (63824-955-74) * 118 mL in 1 BOTTLE * 1...	Mucinex Childrens Day Time Multi-Symptom Cold and Night Time Multi-Symptom Cold	Reckitt Benckiser LLC	2019-01-21
69842-0462-12	1 KIT in 1 KIT (69842-462-12) * 177 mL in 1 BOTTLE, PLASTI...	Daytime Mucus Relief Severe Congestion and Cough and Nighttime Cold and Flu Maximum Strength	CVS Pharmacy	2018-04-30
69842-0820-08	1 KIT in 1 KIT (69842-820-08) * 118 mL in 1 BOTTLE, PLASTI...	Multi Symptom Cold and Multi Symptom Nighttime Cold Childrens	CVS Pharmacy	2017-02-28
82442-0476-08	1 KIT in 1 CARTON (82442-476-08) * 118 mL in 1 BOTTLE (824...	up and up Daytime Nighttime Childrens Multi Symptom Cold	Target Corporation	2024-07-19

Observed labelers: Reckitt Benckiser LLC (6) · Walgreens (6) · CVS PHARMACY (3) · TARGET Corporation (3) · Dolgencorp, Inc. (DOLLAR GENERAL & REXALL) (2) · Haleon US Holdings LLC (2) · +2 more — this is the FDA-listed mapping footprint, not sales, inventory, availability, or market share.

🗃️ Sources & Limits

Atlas generation902fddb9-e9c1-4004-bf4c-dba4d51037c7

openFDA export observedJul 14, 2026

RxNorm release07/06/2026

Methodology2026-07-full-catalog-v1

A shared RxCUI does not prove interchangeability. Products mapped to the same concept are not thereby equivalent or substitutable — equivalence is a separate, product-level determination.
Listing here does not establish approval or coverage. Appearing in this snapshot is a data observation, not an FDA approval status or a payer coverage decision.
Missing data never means zero. A silent dataset (no price, no billing code, no utilization) means no observation — not that the real-world value is zero.
Counts describe the mapping footprint. Product, package, and labeler counts are the FDA-listed mapping footprint in this snapshot — not sales, inventory, availability, or market share.

This product uses publicly available data from the U.S. National Library of Medicine (NLM), National Institutes of Health, Department of Health and Human Services; NLM is not responsible for the product and does not endorse or recommend this or any other product.

Machine-readable JSON

Reference information about drug-concept identifiers and public regulatory data — not medical advice. Talk to your pharmacist or prescriber about your own medication.