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Lisinopril 20 MG Oral Tablet [Zestril] — RxCUI 104378

Name: Lisinopril 20 MG Oral Tablet [Zestril] (RxCUI 104378)
Creator: Brian Staiger, PharmD

RxNorm drug concept · Semantic branded drug

RxCUI 104378 Semantic branded drug · SBD ● Current RxNorm concept 6 FDA products 6 package NDCs Snapshot Jul 14, 2026

This page is curated, coded, and maintained by Dr. Brian Staiger, PharmD

Compiled from public NLM RxNorm and FDA (openFDA NDC directory) data sources. Editorial policy

What you’re looking at: the standardized identity of one medicine, as the U.S. drug-data system sees it. Below — every FDA-listed product, package code, price benchmark, and billing code that maps to it.

🗂️ Key Facts

RxCUI104378

Official nameLisinopril 20 MG Oral Tablet [Zestril]

Concept typeSemantic branded drug (SBD)

RxNorm statusCurrent RxNorm concept

Also known asZestril 20 MG Oral Tablet; Zestril 20 MG Oral Tablet, Once-Daily

FDA products mapped6

Package NDCs mapped6

RxNorm release07/06/2026

Snapshot dataJul 14, 2026

📖 Skip the Codes — Read It in Plain English.

Our pharmacist-built guide to Lisinopril: what it is, how it’s used, side effects, and interactions.

📗 Our plain-language guide HelloPharmacist

It lowers high blood pressure and is used as add-on treatment for heart failure. It is also used soon after a heart attack to improve survival. Lowering blood pressure helps reduce...
You usually take it by mouth once a day. Tablets can be taken with or without food. Follow your prescriber's directions, because the dose is adjusted to your blood pressure.
Headache, dizziness, cough and tiredness are the most common. Stand up slowly if you feel lightheaded. Tell me or your doctor if they bother you or don't go away.
Get emergency help for swelling of the face, lips, tongue or throat, or trouble breathing. Call your doctor for fainting, yellow skin or eyes, severe belly pain, or very little uri...

📖 Read our full Lisinopril guide →

🕸️ Concept Web — How Lisinopril 20 MG Oral Tablet [Zestril] Connects

One RxCUI never lives alone. Follow the path from the raw ingredient down to the exact strength-and-form concepts FDA products carry — every stop is a real RxNorm concept with its own identifier. Hover or focus any chip for what it means.

This page's concept Lisinopril 20 MG Oral Tablet [Zestril] RxCUI 104378 Semantic branded drug · SBD

Every web starts here: one RxCUI, one fixed meaning in the RxNorm vocabulary.

Ingredients 1

The active substance itself — no strength, form, or brand attached yet.
- Lisinopril 29046 IN
Brand names 1

The same medicine's trade names. A brand name alone says nothing about strength or form.
- Zestril 196472 BN
Dose forms 9

The ingredient poured into a form — tablet, solution, cream — still without one fixed strength.
- Lisinopril Oral Tablet 372614 SCDF
- Lisinopril Oral Product 1164689 SCDG
- Lisinopril Pill 1164690 SCDG
- Lisinopril Oral Tablet [Zestril] 368248 SBDF
- Zestril Oral Product 1187283 SBDG
- Zestril Pill 1187284 SBDG
- Oral Tablet 317541 DF
- Oral Product 1151131 DFG
- +1 more in this family
Clinical & branded drugs 3

Ingredient + strength + dose form. These are the concepts real FDA products actually carry.
- Lisinopril 20 MG Oral Tablet 314077 SCD
- Lisinopril 20 MG 316153 SCDC
- Lisinopril 20 MG [Zestril] 563612 SBDC

Showing up to 8 concepts per family — 13 of 14 stored related concepts drawn.

These are official RxNorm vocabulary relationships — how concepts name and organize the same medicine. They do not establish therapeutic equivalence or substitutability: two concepts appearing in one web is never a statement that products can be swapped.

🔀 Generic ⇄ Brand Crosswalk

The same medicine has an unbranded (generic) identity and one or more brand-name identities — each with its own RxCUI. This is a naming relationship in RxNorm, not a statement that any two products are substitutable.

Generic (Clinical) Concepts

Lisinopril 20 MG Oral Tablet SCD · 314077
Lisinopril 20 MG SCDC · 316153
Lisinopril Oral Tablet SCDF · 372614
Lisinopril Oral Product SCDG · 1164689
Lisinopril Pill SCDG · 1164690

Brand-Name Concepts

Lisinopril 20 MG [Zestril] SBDC · 563612
Lisinopril Oral Tablet [Zestril] SBDF · 368248
Zestril Oral Product SBDG · 1187283
Zestril Pill SBDG · 1187284
Zestril BN · 196472

📦 FDA Products & Package NDCs

6 products · 6 package NDCs

6 package NDCs map to RxCUI 104378 in the current snapshot — up to 50 per page. Each linked NDC opens its full package page.

Package NDC	Package	Brand / generic name	Labeler	Marketing start
24979-0238-07	90 TABLET in 1 BOTTLE (24979-238-07)	Zestril	Upsher-Smith Laboratories, LLC	2024-04-25
24979-0239-07	90 TABLET in 1 BOTTLE (24979-239-07)	Zestril	Upsher-Smith Laboratories, LLC	2024-04-25
24979-0240-07	90 TABLET in 1 BOTTLE (24979-240-07)	Zestril	Upsher-Smith Laboratories, LLC	2024-04-25
24979-0241-07	90 TABLET in 1 BOTTLE (24979-241-07)	Zestril	Upsher-Smith Laboratories, LLC	2024-04-25
24979-0242-07	90 TABLET in 1 BOTTLE (24979-242-07)	Zestril	Upsher-Smith Laboratories, LLC	2024-04-25
24979-0243-07	90 TABLET in 1 BOTTLE (24979-243-07)	Zestril	Upsher-Smith Laboratories, LLC	2024-04-25

Observed labelers: Upsher-Smith Laboratories, LLC (6) — this is the FDA-listed mapping footprint, not sales, inventory, availability, or market share.

🗃️ Sources & Limits

Atlas generation902fddb9-e9c1-4004-bf4c-dba4d51037c7

openFDA export observedJul 14, 2026

RxNorm release07/06/2026

Methodology2026-07-full-catalog-v1

A shared RxCUI does not prove interchangeability. Products mapped to the same concept are not thereby equivalent or substitutable — equivalence is a separate, product-level determination.
Listing here does not establish approval or coverage. Appearing in this snapshot is a data observation, not an FDA approval status or a payer coverage decision.
Missing data never means zero. A silent dataset (no price, no billing code, no utilization) means no observation — not that the real-world value is zero.
Counts describe the mapping footprint. Product, package, and labeler counts are the FDA-listed mapping footprint in this snapshot — not sales, inventory, availability, or market share.

This product uses publicly available data from the U.S. National Library of Medicine (NLM), National Institutes of Health, Department of Health and Human Services; NLM is not responsible for the product and does not endorse or recommend this or any other product.

Machine-readable JSON

Reference information about drug-concept identifiers and public regulatory data — not medical advice. Talk to your pharmacist or prescriber about your own medication.