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Acetaminophen 325 MG / chlorpheniramine maleate 2 MG / phenylephrine hydrochloride 5 MG Or... — RxCUI 1046781

RxNorm drug concept · Semantic clinical drug
RxCUI 1046781 Semantic clinical drug · SCD ● Current RxNorm concept 32 FDA products 45 package NDCs Snapshot Jul 14, 2026

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Compiled from public NLM RxNorm and FDA (openFDA NDC directory) data sources. Editorial policy

What you’re looking at: the standardized identity of one medicine, as the U.S. drug-data system sees it. Below — every FDA-listed product, package code, price benchmark, and billing code that maps to it.

🗂️ Key Facts

RxCUI1046781
Official nameAcetaminophen 325 MG / chlorpheniramine maleate 2 MG / phenylephrine hydrochloride 5 MG Oral Tablet
Concept typeSemantic clinical drug (SCD)
RxNorm statusCurrent RxNorm concept
Also known asAPAP 325 MG / chlorpheniramine maleate 2 MG / phenylephrine hydrochloride 5 MG Oral Tablet; acetaminophen 325 MG / chlorpheniramine maleate 2 MG / phenylephrine HCl 5 MG Oral Tablet
FDA products mapped32
Package NDCs mapped45
RxNorm release07/06/2026
Snapshot dataJul 14, 2026

📖 Skip the Codes — Read It in Plain English.

Our pharmacist-built guide to Phenylephrine: what it is, how it’s used, side effects, and interactions.

📗 Our plain-language guide HelloPharmacist
  • It depends on the product. The injection raises low blood pressure during anesthesia and, for some products, septic shock. Eye drops dilate the pupil, nasal products relieve conges...
  • Be careful. Over-the-counter phenylephrine should not be used with a prescription MAOI or within 2 weeks of stopping one. If you aren't sure whether your medicine is an MAOI, ask m...
  • With the injection, the most common are nausea, vomiting and headache. Call for help right away if you have chest pain, a very slow heartbeat, or pain or skin changes around the IV...
  • Stop and talk to a doctor if you get nervousness, dizziness or sleeplessness. Also stop if symptoms last more than 7 days or come with a fever. Don't use more than the label recomm...
📖 Read our full Phenylephrine guide →

🕸️ Concept Web — How Acetaminophen 325 MG / chlorpheniramine maleate... Connects

One RxCUI never lives alone. Follow the path from the raw ingredient down to the exact strength-and-form concepts FDA products carry — every stop is a real RxNorm concept with its own identifier. Hover or focus any chip for what it means.
This page's concept Acetaminophen 325 MG / chlorpheniramine maleate 2 MG / phenylephrine hydrochloride 5 MG Oral Tablet RxCUI 1046781

Every web starts here: one RxCUI, one fixed meaning in the RxNorm vocabulary.

  1. Ingredients 6

    The active substance itself — no strength, form, or brand attached yet.

    • Acetaminophen 161
    • Chlorpheniramine 2400
    • Phenylephrine 8163
    • Acetaminophen / chlorpheniramine / phenylephrine 689583
    • Chlorpheniramine maleate 142429
    • Phenylephrine hydrochloride 8164
  2. Dose forms 9

    The ingredient poured into a form — tablet, solution, cream — still without one fixed strength.

    • Acetaminophen / chlorpheniramine / phenylephrine Oral Tablet 374739
    • Acetaminophen / chlorpheniramine maleate / phenylephrine hydrochloride Oral Tablet 2646973
    • Acetaminophen / chlorpheniramine / phenylephrine Oral Product 1155249
    • Acetaminophen / chlorpheniramine / phenylephrine Pill 1155250
    • Acetaminophen / chlorpheniramine maleate / phenylephrine hydrochloride Oral Product 2663536
    • Acetaminophen / chlorpheniramine maleate / phenylephrine hydrochloride Pill 2662311
    • Oral Tablet 317541
    • Oral Product 1151131
    • +1 more in this family
  3. Clinical & branded drugs 3

    Ingredient + strength + dose form. These are the concepts real FDA products actually carry.

    • Acetaminophen 325 MG 315263
    • Chlorpheniramine maleate 2 MG 999433
    • Phenylephrine hydrochloride 5 MG 1020198
  4. Packs 1

    Fixed collections of drugs packaged and sold together, like dose packs.

Showing up to 8 concepts per family — 18 of 19 stored related concepts drawn.
These are official RxNorm vocabulary relationships — how concepts name and organize the same medicine. They do not establish therapeutic equivalence or substitutability: two concepts appearing in one web is never a statement that products can be swapped.

🔀 Generic ⇄ Brand Crosswalk

The same medicine has an unbranded (generic) identity and one or more brand-name identities — each with its own RxCUI. This is a naming relationship in RxNorm, not a statement that any two products are substitutable.

Generic (Clinical) Concepts

📦 FDA Products & Package NDCs

32 products · 45 package NDCs
45 package NDCs map to RxCUI 1046781 in the current snapshot — up to 50 per page. Each linked NDC opens its full package page.
Package NDC Package Brand / generic name Labeler Marketing start
00135-0578-01 1 BLISTER PACK in 1 CARTON (0135-0578-01) / 12 TABLET in 1... FLONASE Headache and Allergy Relief Haleon US Holdings LLC 2022-03-10
00135-0578-02 4 BLISTER PACK in 1 CARTON (0135-0578-02) / 48 TABLET in 1... FLONASE Headache and Allergy Relief Haleon US Holdings LLC 2022-03-10
00135-0578-03 8 BLISTER PACK in 1 CARTON (0135-0578-03) / 96 TABLET in 1... FLONASE Headache and Allergy Relief Haleon US Holdings LLC 2022-03-10
00363-0559-08 2 BLISTER PACK in 1 CARTON (0363-0559-08) / 12 TABLET, COAT... Multi-Symptom Allergy Walgreen Company 2008-03-27
00924-0091-01 50 PACKET in 1 CARTON (0924-0091-01) / 2 TABLET, FILM COATE... PhysiciansCare Allergy Multi-Symptom Relief Acme United Corporation 2011-12-23
36800-0628-02 2 BLISTER PACK in 1 CARTON (36800-628-02) / 12 TABLET, COAT... Allergy Multi Symptom TOPCO ASSOCIATES LLC 2021-07-23
37808-0628-02 2 BLISTER PACK in 1 CARTON (37808-628-02) / 12 TABLET, COAT... Allergy Multi Symptom HEB 2020-07-31
46122-0660-62 2 BLISTER PACK in 1 CARTON (46122-660-62) / 12 TABLET, COAT... Allergy Multi Symptom AMERISOURCE BERGEN 2020-11-13
47682-0120-13 250 PACKET in 1 BOX (47682-120-13) / 2 TABLET, FILM COATED... Medique Medicidin D Unifirst First Aid Corporation 2008-12-30
47682-0120-33 50 PACKET in 1 BOX (47682-120-33) / 2 TABLET, FILM COATED i... Medique Medicidin D Unifirst First Aid Corporation 2008-12-30
47682-0120-47 100 PACKET in 1 BOX (47682-120-47) / 2 TABLET, FILM COATED... Medique Medicidin D Unifirst First Aid Corporation 2008-12-30
47682-0120-64 12 PACKET in 1 BOX (47682-120-64) / 2 TABLET, FILM COATED i... Medique Medicidin D Unifirst First Aid Corporation 2008-12-30
47682-0120-99 2 TABLET, FILM COATED in 1 PACKET (47682-120-99) Medique Medicidin D Unifirst First Aid Corporation 2008-12-30
47682-0543-03 150 PACKET in 1 BOX (47682-543-03) / 2 TABLET, FILM COATED... Otis Clapp Valihist Unifirst First Aid Corporation 2008-12-30
47682-0543-99 2 TABLET, FILM COATED in 1 PACKET (47682-543-99) Otis Clapp Valihist Unifirst First Aid Corporation 2008-12-30
50332-0153-04 100 TABLET, COATED in 1 BOX, UNIT-DOSE (50332-0153-4) Relief-PE HART Health 2012-04-16
50332-0153-07 250 TABLET, COATED in 1 BOX, UNIT-DOSE (50332-0153-7) Relief-PE HART Health 2012-04-16
50804-0128-02 2 BLISTER PACK in 1 CARTON (50804-128-02) / 12 TABLET, COAT... Allergy Multi Symptom GOODSENSE 2020-08-01
50844-0455-08 2 BLISTER PACK in 1 CARTON (50844-455-08) / 12 TABLET, FILM... Allergy Multi-Symptom L.N.K. International, Inc. 2005-06-28
51467-0005-01 2 BLISTER PACK in 1 BOX (51467-005-01) / 12 TABLET in 1 BLI... COLTALIN FORTUNE PHARMACAL COMPANY LIMITED 2004-03-01
51467-0005-02 3 BLISTER PACK in 1 BOX (51467-005-02) / 12 TABLET in 1 BLI... COLTALIN FORTUNE PHARMACAL COMPANY LIMITED 2016-04-26
51467-0010-01 2 BLISTER PACK in 1 BOX (51467-010-01) / 12 TABLET in 1 BLI... Extra Fast Coltalin FORTUNE PHARMACAL COMPANY LIMITED 2017-04-04
51467-0010-02 3 BLISTER PACK in 1 BOX (51467-010-02) / 12 TABLET in 1 BLI... Extra Fast Coltalin FORTUNE PHARMACAL COMPANY LIMITED 2017-04-04
51467-0011-01 2 BLISTER PACK in 1 BOX (51467-011-01) / 12 TABLET in 1 BLI... COLTALIN FORTUNE PHARMACAL COMPANY LIMITED 2026-01-30
51467-0011-02 3 BLISTER PACK in 1 BOX (51467-011-02) / 12 TABLET in 1 BLI... COLTALIN FORTUNE PHARMACAL COMPANY LIMITED 2026-01-30
51467-0014-01 2 BLISTER PACK in 1 BOX (51467-014-01) / 12 TABLET in 1 BLI... EXTRA FAST COLTALIN FORTUNE PHARMACAL COMPANY LIMITED 2026-01-30
51467-0014-02 3 BLISTER PACK in 1 BOX (51467-014-02) / 12 TABLET in 1 BLI... EXTRA FAST COLTALIN FORTUNE PHARMACAL COMPANY LIMITED 2026-01-30
53145-0005-02 50 PACKAGE in 1 CARTON (53145-005-02) / 2 TABLET in 1 PACKA... Defensol D Menper Distributors, Inc. 2012-02-21
53145-0005-30 1 BOTTLE in 1 BOX (53145-005-30) / 30 TABLET in 1 BOTTLE Defensol D Menper Distributors, Inc. 2012-02-21
53943-0228-02 2 BLISTER PACK in 1 CARTON (53943-228-02) / 12 TABLET, COAT... ALLERGY MULTISYMPTOM DISCOUNT DRUG MART 2008-09-09
55301-0455-08 2 BLISTER PACK in 1 CARTON (55301-455-08) / 12 TABLET, FILM... Allergy Multi-Symptom ARMY AND AIR FORCE EXCHANGE SERVICE 2005-06-28
55910-0455-08 2 BLISTER PACK in 1 CARTON (55910-455-08) / 12 TABLET, FILM... Allergy Multi-Symptom DOLGENCORP, LLC 2005-06-28
57344-0928-02 2 BLISTER PACK in 1 CARTON (57344-928-02) / 12 TABLET, COAT... Allergy Multi Symptom AAA PHARMACEUTICAL, INC. 2020-08-01
59779-0779-08 1 KIT in 1 CARTON (59779-779-08) * 12 TABLET, FILM COATED... SINUS PAIN AND CONGESTION CVS Pharmacy 2005-07-26
63654-0275-20 2 BLISTER PACK in 1 CARTON (63654-275-20) / 10 TABLET in 1... Cold Medicine Selder, S.A. de C.V. 2011-11-15
63654-0605-20 2 BLISTER PACK in 1 BOX (63654-605-20) / 10 TABLET in 1 BLI... Cold Medicine XL3 Selder, S.A. de C.V. 2022-06-27
63868-0578-24 2 BLISTER PACK in 1 CARTON (63868-578-24) / 12 TABLET, COAT... Allergy Multisymptom CHAIN DRUG MARKETING ASSOCIATION INC 2020-06-15
66715-9927-03 3 POUCH in 1 CARTON (66715-9927-3) / 2 TABLET in 1 POUCH Allergy Sinus, Lil Drug Store Lil' Drug Store Products, Inc. 2011-02-08
68998-0228-02 2 BLISTER PACK in 1 CARTON (68998-228-02) / 12 TABLET, COAT... Allergy Multi Symptom MARC GLASSMAN, INC. 2020-06-22
69168-0004-51 20 TABLET in 1 CARTON (69168-004-51) Cold Medicine Allegiant Health 2021-11-23
70000-0211-01 2 BLISTER PACK in 1 CARTON (70000-0211-1) / 12 TABLET, FILM... Allergy Multi-Symptom Cardinal Health 110, LLC. DBA Leader 2005-06-28
70677-1004-01 2 BLISTER PACK in 1 CARTON (70677-1004-1) / 12 TABLET, COAT... Allergy Multi-Symptom STRATEGIC SOURCING SERVICES LLC 2023-04-25
72476-0128-02 2 BLISTER PACK in 1 CARTON (72476-128-02) / 12 TABLET, COAT... Allergy MultiSymptom RETAIL BUSINESS SERVICES , LLC. 2020-10-21
76095-0011-20 2 BLISTER PACK in 1 BOX (76095-011-20) / 10 TABLET in 1 BLI... Cold Medicine XL3 Midway Importing, Inc. 2022-06-27
83324-0086-24 2 BLISTER PACK in 1 CARTON (83324-086-24) / 12 TABLET, COAT... Allergy Multi Symptom CHAIN DRUG MARKETING ASSOCIATION, INC. 2024-08-12
Observed labelers: FORTUNE PHARMACAL COMPANY LIMITED (8) · Unifirst First Aid Corporation (7) · Haleon US Holdings LLC (3) · HART Health (2) · Menper Distributors, Inc. (2) · Selder, S.A. de C.V. (2) · +21 more — this is the FDA-listed mapping footprint, not sales, inventory, availability, or market share.

🗃️ Sources & Limits

Atlas generation902fddb9-e9c1-4004-bf4c-dba4d51037c7
openFDA export observedJul 14, 2026
RxNorm release07/06/2026
Methodology2026-07-full-catalog-v1
  • A shared RxCUI does not prove interchangeability. Products mapped to the same concept are not thereby equivalent or substitutable — equivalence is a separate, product-level determination.
  • Listing here does not establish approval or coverage. Appearing in this snapshot is a data observation, not an FDA approval status or a payer coverage decision.
  • Missing data never means zero. A silent dataset (no price, no billing code, no utilization) means no observation — not that the real-world value is zero.
  • Counts describe the mapping footprint. Product, package, and labeler counts are the FDA-listed mapping footprint in this snapshot — not sales, inventory, availability, or market share.
This product uses publicly available data from the U.S. National Library of Medicine (NLM), National Institutes of Health, Department of Health and Human Services; NLM is not responsible for the product and does not endorse or recommend this or any other product.

Machine-readable JSON

Reference information about drug-concept identifiers and public regulatory data — not medical advice. Talk to your pharmacist or prescriber about your own medication.