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Diphenhydramine hydrochloride 25 MG Oral Capsule — RxCUI 1049909

RxNorm drug concept · Semantic clinical drug
RxCUI 1049909 Semantic clinical drug · SCD ● Current RxNorm concept 127 FDA products 245 package NDCs Snapshot Jul 14, 2026

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Compiled from public NLM RxNorm and FDA (openFDA NDC directory) data sources. Editorial policy

What you’re looking at: the standardized identity of one medicine, as the U.S. drug-data system sees it. Below — every FDA-listed product, package code, price benchmark, and billing code that maps to it.

🗂️ Key Facts

RxCUI1049909
Official nameDiphenhydramine hydrochloride 25 MG Oral Capsule
Concept typeSemantic clinical drug (SCD)
RxNorm statusCurrent RxNorm concept
Also known asdiphenhydrAMINE HCl 25 MG Oral Capsule
FDA products mapped127
Package NDCs mapped245
Reported Medicaid activity (SDUD)272,172 prescriptions · 45 state & territory Medicaid programs · latest period Q4 2025
RxNorm release07/06/2026
Snapshot dataJul 14, 2026

📖 Skip the Codes — Read It in Plain English.

Our pharmacist-built guide to Diphenhydramine Topical: what it is, how it’s used, side effects, and interactions.

📗 Our plain-language guide HelloPharmacist
  • It gives temporary relief of pain and itching on the skin. That includes minor burns, minor cuts or scrapes, insect bites, minor skin irritations, and rashes from poison ivy, oak o...
  • Adults and children 2 and older can apply it to the affected area no more than 3 to 4 times a day. Don't use it more often than directed. For a child under 2, check with a doctor f...
  • No. Don't use it on large areas of the body or on broken, blistered or oozing skin. Also avoid it on chicken pox or sunburn.
  • Can I put it on a large area or on blistered skin?
📖 Read our full Diphenhydramine Topical guide →

🕸️ Concept Web — How Diphenhydramine hydrochloride 25 MG Oral Capsule Connects

One RxCUI never lives alone. Follow the path from the raw ingredient down to the exact strength-and-form concepts FDA products carry — every stop is a real RxNorm concept with its own identifier. Hover or focus any chip for what it means.
This page's concept Diphenhydramine hydrochloride 25 MG Oral Capsule RxCUI 1049909

Every web starts here: one RxCUI, one fixed meaning in the RxNorm vocabulary.

  1. Ingredients 2

    The active substance itself — no strength, form, or brand attached yet.

    • Diphenhydramine 3498
    • Diphenhydramine hydrochloride 1362
  2. Brand names 10

    The same medicine's trade names. A brand name alone says nothing about strength or form.

    • Banophen 215558
    • Benadryl 203457
    • Diphedryl 216654
    • Diphenhist 216660
    • Dormin 1919068
    • Genahist 217286
    • Unisom Sleep 1093099
    • Wal-Dryl Allergy 1090073
    • +2 more in this family
  3. Dose forms 49

    The ingredient poured into a form — tablet, solution, cream — still without one fixed strength.

    • Diphenhydramine Oral Capsule 371891
    • Diphenhydramine hydrochloride Oral Capsule 2647158
    • Diphenhydramine Oral Product 1158449
    • Diphenhydramine Pill 1158450
    • Diphenhydramine hydrochloride Oral Product 2659104
    • Diphenhydramine hydrochloride Pill 2659100
    • Diphenhydramine Oral Capsule [Banophen] 366259
    • Diphenhydramine Oral Capsule [Benadryl] 366257
    • +41 more in this family
  4. Clinical & branded drugs 21

    Ingredient + strength + dose form. These are the concepts real FDA products actually carry.

Showing up to 8 concepts per family — 26 of 82 stored related concepts drawn.
These are official RxNorm vocabulary relationships — how concepts name and organize the same medicine. They do not establish therapeutic equivalence or substitutability: two concepts appearing in one web is never a statement that products can be swapped.

🔀 Generic ⇄ Brand Crosswalk

The same medicine has an unbranded (generic) identity and one or more brand-name identities — each with its own RxCUI. This is a naming relationship in RxNorm, not a statement that any two products are substitutable.

Generic (Clinical) Concepts

  • Diphenhydramine hydrochloride 25 MG SCDC · 901813
  • Diphenhydramine Oral Capsule SCDF · 371891
  • Diphenhydramine hydrochloride Oral Capsule SCDFP · 2647158
  • Diphenhydramine Oral Product SCDG · 1158449
  • Diphenhydramine Pill SCDG · 1158450
  • Diphenhydramine hydrochloride Oral Product SCDGP · 2659104
  • Diphenhydramine hydrochloride Pill SCDGP · 2659100

Brand-Name Concepts

📦 FDA Products & Package NDCs

127 products · 245 package NDCs
245 package NDCs map to RxCUI 1049909 in the current snapshot — up to 50 per page. Each linked NDC opens its full package page.
Package NDC Package Brand / generic name Labeler Marketing start
00363-1170-24 24 BLISTER PACK in 1 CARTON (0363-1170-24) / 2 CAPSULE, LIQ... Allergy Relief Dye Free WALGREENS 2020-02-06
00363-1170-48 24 BLISTER PACK in 1 CARTON (0363-1170-48) / 4 CAPSULE, LIQ... Allergy Relief Dye Free WALGREENS 2020-12-17
00363-1174-24 2 BLISTER PACK in 1 CARTON (0363-1174-24) / 12 CAPSULE, LIQ... NIGHTTIME SLEEP AID WALGREEN COMPANY 2023-10-21
00363-1174-48 4 BLISTER PACK in 1 CARTON (0363-1174-48) / 12 CAPSULE, LIQ... NIGHTTIME SLEEP AID WALGREEN COMPANY 2023-10-21
00363-1175-24 2 BLISTER PACK in 1 CARTON (0363-1175-24) / 12 CAPSULE, LIQ... Free and Pure Allergy Relief Dye Free WALGREEN COMPANY 2023-10-22
00363-1175-48 4 BLISTER PACK in 1 CARTON (0363-1175-48) / 12 CAPSULE, LIQ... Free and Pure Allergy Relief Dye Free WALGREEN COMPANY 2023-10-22
00363-1900-07 3 BLISTER PACK in 1 CARTON (0363-1900-07) / 12 CAPSULE in 1... Allergy Relief Walgreen Company 2024-12-30
00363-1900-08 2 BLISTER PACK in 1 CARTON (0363-1900-08) / 12 CAPSULE in 1... Allergy Relief Walgreen Company 2021-09-17
00363-1900-12 1 BOTTLE, PLASTIC in 1 CARTON (0363-1900-12) / 100 CAPSULE... Allergy Relief Walgreen Company 2025-12-11
00363-1900-51 365 CAPSULE in 1 BOTTLE, PLASTIC (0363-1900-51) Allergy Relief Walgreen Company 2021-09-17
00363-1900-78 600 CAPSULE in 1 BOTTLE, PLASTIC (0363-1900-78) Allergy Relief Walgreen Company 2025-12-16
00363-6130-24 2 BLISTER PACK in 1 CARTON (0363-6130-24) / 12 CAPSULE in 1... Sleep Aid WALGREENS 2025-09-01
00363-6130-48 4 BLISTER PACK in 1 CARTON (0363-6130-48) / 12 CAPSULE in 1... Sleep Aid WALGREENS 2025-09-01
00363-6682-24 2 BLISTER PACK in 1 CARTON (0363-6682-24) / 12 CAPSULE, LIQ... Allergy Relief Dye Free Walgreens 2025-06-01
00363-6682-48 4 BLISTER PACK in 1 CARTON (0363-6682-48) / 12 CAPSULE, LIQ... Allergy Relief Dye Free Walgreens 2025-06-01
00363-8350-01 1 BOTTLE in 1 CARTON (0363-8350-01) / 100 CAPSULE in 1 BOTT... Diphenhydramine Hydrochloride Walgreen Company 2024-02-02
00363-8350-02 600 CAPSULE in 1 BOTTLE (0363-8350-02) Diphenhydramine Hydrochloride Walgreen Company 2022-10-17
00363-8350-06 365 CAPSULE in 1 BOTTLE (0363-8350-06) Diphenhydramine Hydrochloride Walgreen Company 2022-08-12
00363-8989-12 1 BLISTER PACK in 1 CARTON (0363-8989-12) / 12 CAPSULE, LIQ... NIGHTTIME SLEEP AID WALGREEN COMPANY 2020-12-22
00363-8989-24 2 BLISTER PACK in 1 CARTON (0363-8989-24) / 12 CAPSULE, LIQ... NIGHTTIME SLEEP AID WALGREEN COMPANY 2020-12-22
00363-8989-48 4 BLISTER PACK in 1 CARTON (0363-8989-48) / 12 CAPSULE, LIQ... NIGHTTIME SLEEP AID WALGREEN COMPANY 2020-12-22
00363-9835-01 1 BOTTLE in 1 CARTON (0363-9835-01) / 100 CAPSULE in 1 BOTT... Diphenhydramine Hydrochloride Walgreen Company 2021-09-07
00363-9835-02 600 CAPSULE in 1 BOTTLE (0363-9835-02) Diphenhydramine Hydrochloride Walgreen Company 2022-05-05
00363-9835-06 365 CAPSULE in 1 BOTTLE (0363-9835-06) Diphenhydramine Hydrochloride Walgreen Company 2021-10-01
00904-2056-61 10 BLISTER PACK in 1 BOX (0904-2056-61) / 10 CAPSULE in 1 B... Diphenhydramine Hydrochloride Major Pharmaceuticals 2009-01-02
00904-7237-24 2 BLISTER PACK in 1 CARTON (0904-7237-24) / 12 CAPSULE in 1... Diphenhydramine Hydrochloride Major Pharmaceuticals 2022-04-14
00904-7237-60 100 CAPSULE in 1 BOTTLE (0904-7237-60) Diphenhydramine Hydrochloride Major Pharmaceuticals 2022-04-14
00904-7237-61 10 BLISTER PACK in 1 BOX, UNIT-DOSE (0904-7237-61) / 10 CAP... Diphenhydramine Hydrochloride Major Pharmaceuticals 2022-04-14
00904-7237-80 1000 CAPSULE in 1 BOTTLE (0904-7237-80) Diphenhydramine Hydrochloride Major Pharmaceuticals 2022-04-14
11673-0703-24 2 BLISTER PACK in 1 CARTON (11673-703-24) / 12 CAPSULE, LIQ... Nighttime Sleep Aid TARGET CORPORATION 2024-01-15
11673-0703-48 4 BLISTER PACK in 1 CARTON (11673-703-48) / 12 CAPSULE, LIQ... Nighttime Sleep Aid TARGET CORPORATION 2024-01-15
11822-0190-01 1 BOTTLE in 1 CARTON (11822-0190-1) / 100 CAPSULE in 1 BOTT... Allergy Relief Rite Aid Corporation 1990-03-15
11822-0190-08 2 BLISTER PACK in 1 CARTON (11822-0190-8) / 12 CAPSULE in 1... Allergy Relief Rite Aid Corporation 1990-03-15
16103-0348-08 1 BOTTLE, PLASTIC in 1 CARTON (16103-348-08) / 100 CAPSULE... Pharbedryl Pharbest Pharmaceuticals, Inc. 2016-02-01
16103-0348-11 1000 CAPSULE in 1 BOTTLE, PLASTIC (16103-348-11) Pharbedryl Pharbest Pharmaceuticals, Inc. 2016-02-01
17714-0020-01 100 CAPSULE in 1 BOTTLE (17714-020-01) Diphenhydramine Hydrochloride Advance Pharmaceutical Inc. 1989-09-12
17714-0020-10 1000 CAPSULE in 1 BOTTLE (17714-020-10) Diphenhydramine Hydrochloride Advance Pharmaceutical Inc. 1989-09-12
30142-0554-24 2 BLISTER PACK in 1 CARTON (30142-554-24) / 12 CAPSULE, LIQ... Kroger Allergy Relief THE KROGER CO 2021-03-17
30142-0832-48 4 BLISTER PACK in 1 CARTON (30142-832-48) / 12 CAPSULE in 1... Allergy Antihistamine KROGER COMPANY 2021-05-01
30142-0832-84 1 BOTTLE in 1 CARTON (30142-832-84) / 100 CAPSULE in 1 BOTT... Allergy Antihistamine KROGER COMPANY 2021-05-01
35916-0435-01 3 CAPSULE, LIQUID FILLED in 1 CARTON (35916-0435-1) DIPHENHYDRAMINE HYDROCHLORIDE SOFTGEL HEALTHCARE PRIVATE LIMITED 2023-08-07
35916-0435-03 1000 CAPSULE, LIQUID FILLED in 1 BAG (35916-0435-3) DIPHENHYDRAMINE HYDROCHLORIDE SOFTGEL HEALTHCARE PRIVATE LIMITED 2025-04-22
35916-0435-04 2 POUCH in 1 BOX (35916-0435-4) / 3000 CAPSULE, LIQUID FILL... DIPHENHYDRAMINE HYDROCHLORIDE SOFTGEL HEALTHCARE PRIVATE LIMITED 2025-06-11
35916-0435-05 2 BAG in 1 BOX (35916-0435-5) / 1500 CAPSULE, LIQUID FILLED... DIPHENHYDRAMINE HYDROCHLORIDE SOFTGEL HEALTHCARE PRIVATE LIMITED 2026-01-24
35916-0436-02 1000 CAPSULE, LIQUID FILLED in 1 BAG (35916-0436-2) DIPHENHYDRAMINE HYDROCHLORIDE SOFTGEL HEALTHCARE PRIVATE LIMITED 2025-04-07
35916-0471-01 1000 CAPSULE, LIQUID FILLED in 1 BAG (35916-0471-1) DIPHENHYDRAMINE HYDROCHLORIDE SOFTGEL HEALTHCARE PRIVATE LIMITED 2025-04-22
36800-0367-24 2 BLISTER PACK in 1 CARTON (36800-367-24) / 12 CAPSULE, LIQ... TopCare Allergy Relief TOPCO ASSOCIATES LLC 2021-07-13
36800-0910-01 2 BLISTER PACK in 1 CARTON (36800-910-01) / 12 CAPSULE in 1... Allergy Relief TopCo Associates LLC 2011-08-30
36800-0910-02 4 BLISTER PACK in 1 CARTON (36800-910-02) / 12 CAPSULE in 1... Allergy Relief TopCo Associates LLC 2011-08-30
36800-0910-03 1 BOTTLE, PLASTIC in 1 CARTON (36800-910-03) / 100 CAPSULE... Allergy Relief TopCo Associates LLC 2011-08-30
Observed labelers: Bryant Ranch Prepack (20) · Walgreen Company (18) · PD-Rx Pharmaceuticals, Inc. (11) · CVS Pharmacy, Inc (9) · The Procter & Gamble Manufacturing Company (7) · Wal-Mart Stores Inc (7) · +79 more — this is the FDA-listed mapping footprint, not sales, inventory, availability, or market share.

🗃️ Sources & Limits

Atlas generation902fddb9-e9c1-4004-bf4c-dba4d51037c7
openFDA export observedJul 14, 2026
RxNorm release07/06/2026
Methodology2026-07-full-catalog-v1
  • A shared RxCUI does not prove interchangeability. Products mapped to the same concept are not thereby equivalent or substitutable — equivalence is a separate, product-level determination.
  • Listing here does not establish approval or coverage. Appearing in this snapshot is a data observation, not an FDA approval status or a payer coverage decision.
  • Missing data never means zero. A silent dataset (no price, no billing code, no utilization) means no observation — not that the real-world value is zero.
  • Counts describe the mapping footprint. Product, package, and labeler counts are the FDA-listed mapping footprint in this snapshot — not sales, inventory, availability, or market share.
This product uses publicly available data from the U.S. National Library of Medicine (NLM), National Institutes of Health, Department of Health and Human Services; NLM is not responsible for the product and does not endorse or recommend this or any other product.

Machine-readable JSON

Reference information about drug-concept identifiers and public regulatory data — not medical advice. Talk to your pharmacist or prescriber about your own medication.