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Diphenhydramine Hydrochloride 25 mg Capsule, 100-count — NDC 00904-7237-60 package photo
Label image from the product's FDA listing (DailyMed) — may show a different pack size or an older label revision.

Diphenhydramine Hydrochloride 25 mg Capsule, 100-count — NDC 0904-7237-60 (Billing 00904-7237-60)

by Major Pharmaceuticals · 100 CAPSULE in 1 BOTTLE

This is a package of 100 capsules of Diphenhydramine Hydrochloride 25 mg Capsule from Major Pharmaceuticals, marketed since Apr 2022 and currently FDA-listed, this package's marketing is listed to end Feb 2028; retail pharmacies pay about $0.0534 per capsule (NADAC).

NDC 00904-7237-60
🏷️ FDA NDC (as labeled) 0904-7237-60 billing pads the labeler segment with a zero
This package
Contains100-count Cost per ea$0.0534 NADAC Per package$5.34 / 100 capsules Pack sizes4 compare ↓
Also priced by: Medicaid pays $0.1589/unit — full pricing hub ↓
Product page 00904-7237-80 Also comes in: 24 capsules 0904-7237-24 100 capsules 0904-7237-61 1000 capsules 0904-7237-80
OTC On market Non-controlled ⇄ Compare with another NDC
🗂️ FDA directory synced Oct 8, 2026 · this listing last changed Jul 24, 2026 · sources: openFDA · FDA label (DailyMed) · FDA Orange & Purple Book · First Databank · CMS NADAC, ASP, Medicare & Medicaid · RxNorm
📋 All sources & update times →

This page is curated, coded, and maintained by

Compiled from public FDA, CMS, DailyMed, NADAC, and related drug data sources. Editorial policy

NDC database record

One package, one record: these facts belong to NDC 0904-7237-60 alone.

Record
FDA NDC Directory package listing · Human OTC drug
Code segments
0904 labeler · 7237 product · 60 package
Package marketed since
Apr 14, 2022
Package marketing ended
Feb 29, 2028
Sample package
No — commercial package
Billing quantity
100 EA per package
Barcode (UPC)
0309047237241
Medicaid fills, this package
74,864 prescriptions in the last four reported quarters
FDA record last changed
Jul 24, 2026

Identity & classification

Regulatory identifiers FDA, NLM and CMS codes for this package

FDA NDC (as labeled) 0904-7237-60
Product NDC 0904-7237
11-digit billing NDC 00904723760
NCPDP billing unit EA — each (per item)
RxCUI 1049909
UNII TC2D6JAD40
UPC 0309047237241
Application # M012
SPL Set ID dca04d80-e781-40b1-e053-2995a90a7010
Established class (EPC) Histamine-1 Receptor Antagonist
Mechanism of action Histamine H1 Receptor Antagonists
DEA schedule Non-controlled
Marketing category OTC MONOGRAPH DRUG
Marketing status On market
FDA listing status Listed (active directory)
Marketing start 2022-04-14
Marketing end 2028-04-30
Route ORAL
Dosage form CAPSULE
Substance DIPHENHYDRAMINE HYDROCHLORIDE

Drug-database identifiers Medi-Span GPI and First Databank GCN / HICL / AHFS classification

GCN Seq No 011582
GCN 45971
HICL code 004480
Ingredient (HICL) Diphenhydramine Hcl
HIC1 code Z
Therapeutic class — broad (HIC1) Body As A Whole
HIC2 code Z2
Therapeutic class — intermediate (HIC2) Antihistamines, Antiserotonins, Immunosuppressants
HIC3 code Z2P
Therapeutic class — specific (HIC3) Antihistamines - 1St Generation
AHFS code 04:04.00.00
AHFS class First Generation Antihistamines
FDB label name BANOPHEN 25 MG CAPSULE
FDB brand name Banophen
Legend status O — Over-the-counter (OTC) drug or device
Quick answers
  • GSN (GCN sequence number): 011582
  • GCN: 45971
  • HICL (First Databank): 004480
  • AHFS class code: 04:04.00.00
  • RxCUI (RxNorm): 1049909
Why two NDCs? The FDA registers this code as 0904-7237-60 — a 4-4-2 layout, and that's what's printed on the package and shown on DailyMed. For insurance claims, every NDC is standardized to a uniform 11-digit 5-4-2 format by adding a zero to the labeler segment → 00904-7237-60. Same drug, same package — only the format differs.
Where does this data come from?
Identifiers from the FDA openFDA NDC Directory and Structured Product Labeling; RxCUI from RxNorm (NLM); GPI from Medi-Span; GCN / HIC / AHFS / legend from First Databank.

RxNorm drug class

This medicine belongs to the Histamine-1 Receptor Antagonist class.

Pharmacologic class Histamine-1 Receptor Antagonist
Drug family (ATC) Propionic acid derivatives, Antihistamines for topical use, Aminoalkyl ethers
How it works Histamine H1 Receptor Antagonists
Where does this data come from?
Therapeutic classes from RxNorm RxClass (U.S. National Library of Medicine) — Established Pharmacologic Class (FDA), ATC drug family (WHO) and mechanism of action, matched by this product’s RxCUI.

Clinical

Label name BANOPHEN 25 MG CAPSULE Ingredient Diphenhydramine Hcl
📖 What it is MedlinePlus · NLM

Diphenhydramine is used to treat allergy and cold symptoms: sneezing runny nose red, itchy, watery eyes itching of the nose or throat Diphenhydramine is also used to treat insomnia (difficulty falling asleep or staying asleep) in adults, but should not be used to make a child sleepy. Diphenhydramine is in a class of medications called antihistamines. It works by blocking the action of histamine, a substance in the body that causes allergic symptoms. Diphenhydramine is also available in combination with other medications. This monograph only includes information about the use of diphenh...

Read the full MedlinePlus article ↗
📗 Our plain-language guide HelloPharmacist
  • Oral products temporarily relieve hay fever and other upper respiratory allergy symptoms like runny nose, sneezing and itchy, watery eyes. They also ease runny nose and sneezing fr...
  • Oral forms are generally taken every 4 to 6 hours, with no more than 6 doses in 24 hours. The amount depends on age and the product, so check the package chart or ask me or your do...
  • It can. Drowsiness is common, so be careful driving or using machinery. Alcohol, sedatives and tranquilizers make it worse, so avoid them.
  • Oral products are not for children under 2 years, and some are not for children under 6. Children can become excitable, and overdose can be very dangerous. Always follow the age di...
📖 Read our full Diphenhydramine guide →

Supplement & herbal interactions

🌿 Drug–supplement interaction checker →
Where does this data come from?
Plain-language summary from MedlinePlus (U.S. National Library of Medicine); supplement & herbal interactions and nutrient depletion data from the Natural Medicines database; our full guide is HelloPharmacist editorial content.

Pricing

A drug doesn't have one price. Each row is a different public payment system, and none is what you'd pay at the counter — that depends on your insurance. The ⓘ on each row explains what it measures.

Price systemPer eaPer package
Retail pharmacies payNADAC · weekly $0.053 $5.34 / 100 capsules
Medicaid paysCMS SDUD · 12 mo $0.1589 $15.89 / 100 capsules
Medicare drug plans payPart D · quarterly No Part D plan price is available for this NDC in our data.
NADAC price history (per ea) — tap or hover for the price & month
Nov 2022 Dec 2025 Apr 2026 Sep 2026 $0.064 $0.034
▲ Up 58% over the last 14 months.
Where does this data come from?
NADAC (National Average Drug Acquisition Cost) is the CMS weekly pharmacy-acquisition-cost survey — what pharmacies pay. ASP (Average Sales Price) is the CMS Medicare Part B drug-payment file, published quarterly. Medicaid pays is computed by us from CMS State Drug Utilization Data (total reimbursed ÷ units, trailing 12 months) — gross of rebates and inclusive of dispensing fees, so it reflects what Medicaid paid, not an acquisition cost. Medicare drug plans pay is the median negotiated point-of-sale unit cost across plans listing this NDC in the CMS quarterly Prescription Drug Plan pricing files, before rebates. The VA pays is the federal contract price (FSS, and the statutory Big 4 ceiling where listed) from the VA National Acquisition Center pharmaceutical price file. All are free public government data; each measures a different payer, so the figures are not directly comparable.

Packaging — all sizes for this product

Package NDCDescription Per unit Per pack Marketing startMarketing endStatus
00904-7237-24 0904-7237-24 2 BLISTER PACK in 1 CARTON / 12 CAPSULE in 1 BLISTER PACK $0.0534 / ea $1.28 2022-04-14 Jan 31, 2028 Active
00904-7237-60 You're viewing this 100 CAPSULE in 1 BOTTLE $0.0534 / ea $5.34 2022-04-14 Feb 29, 2028 Active
00904-7237-61 0904-7237-61 10 BLISTER PACK in 1 BOX, UNIT-DOSE / 10 CAPSULE in 1 BLISTER PACK $0.0534 / ea $5.34 2022-04-14 Feb 29, 2028 Active
00904-7237-80 0904-7237-80 Main listing 1000 CAPSULE in 1 BOTTLE $0.0534 / ea $53.36 2022-04-14 Apr 30, 2028 Active

This pack effectively ties for the lowest per-ea cost of the 4 priced pack sizes ($0.0534 NADAC).

This pack accounts for about 38% of this product's recent Medicaid fills; the largest share goes to the 1000 capsules pack. See all packs ↓

Pack size FAQ

What quantity is in this package?
This is a 100-count package — 100 capsule in 1 bottle.
How does this package differ from NDC 00904-7237-24?
Both are Diphenhydramine Hydrochloride 25 mg Capsule — the drug itself is identical. This page's package is the 100-count one, while NDC 00904-7237-24 is the 24 capsules package.
What NDC number is used to bill for this package of Diphenhydramine Hydrochloride 25 mg Capsule?
Use the 11-digit billing form listed in the identifiers section of this page. Pharmacy and medical claims use the 11-digit form; the FDA label may print a shorter form of the same code.

Prices are the latest CMS NADAC pharmacy acquisition cost per NDC; per-pack figures are per-unit × pack quantity, shown only when the pack is denominated in the same measure NADAC prices.

Therapeutic equivalents

ProductLabelerPackNADAC/unitTEStatusPrice vs. this
Diphenhydramine Hydrochloride 25 mg 42806-0648-10 Epic 1000 capsules $0.034 — FDA listed save 37%
Allergy Relief 25 mg 63868-0087-01 Chain 100 capsules $0.034 — FDA listed save 37%
Diphenhydramine Hydrochloride 25 mgthis 00904-7237-60 Major 100 capsules $0.053 — Availability likely —
Allergy Relief 25 mg 46122-0440-62 Amerisource 24 capsules $0.053 — Availability likely —
Good Neighbor Allergy Relief 25 mg 46122-0699-62 AmerisourceBergen 12 capsules $0.053 — Availability likely —
Allergy Relief 25 mg 46122-0828-51 AMERISOURCE 12 capsules $0.053 — Availability likely —
Dimetane 25 mg 57237-0367-01 Rising 100 capsules $0.053 — Availability likely —
Allergy Relief Diphenhydramine HCl 25 mg 70000-0585-01 Cardinal 12 capsules $0.053 — Availability likely —
Diphenhydramine Hydrochloride 25 mg 70000-0598-01 LEADER/ 24 capsules $0.053 — Availability likely —
Allergy Relief 25 mg 70677-1015-01 Strategic 24 capsules $0.053 — Availability likely —
Diphenhydramine HCl 25 mg 82568-0004-01 AARNA 100 capsules $0.053 — Availability likely —
Allergy Relief 25 mg 83324-0087-01 CHAIN 100 capsules $0.053 — Availability likely —
Quality Choice Allergy Relief 25 mg 83324-0118-24 Chain 12 capsules $0.053 — Availability likely —
Allergy Relief 25 mg 83324-0280-24 CHAIN 12 capsules $0.053 — Availability likely —
Sleep-Aid Diphenhydramine HCl 25 mg 70000-0584-01 Cardinal 12 capsules $0.215 — Availability likely +304%
Free and Pure Allergy Relief Dye Free 25 mg 00363-1175-24 WALGREEN 12 capsules — — FDA listed —
Allergy Relief 25 mg 00363-1900-08 Walgreen 24 capsules — — FDA listed —
Sleep Aid 25 mg 00363-6130-24 WALGREENS 24 capsules — — FDA listed —
Allergy Relief Dye Free 25 mg 00363-6682-24 Walgreens 12 capsules — — FDA listed —
Diphenhydramine Hydrochloride 25 mg 00363-8350-02 Walgreen 600 capsules — — FDA listed —
Nighttime Sleep Aid 25 mg 00363-8989-12 WALGREEN 12 capsules — — FDA listed —
Diphenhydramine Hydrochloride 25 mg 00363-9835-01 Walgreen 100 capsules — — Discontinued —
Nighttime Sleep Aid 25 mg 11673-0703-24 TARGET 12 capsules — — FDA listed —
Allergy Relief 25 mg 11822-0190-01 Rite 100 capsules — — FDA listed —
Pharbedryl 25 mg 16103-0348-03 Pharbest 24 capsules — — FDA listed —
Diphenhydramine Hydrochloride 25 mg 17714-0020-01 Advance 100 capsules — — FDA listed —
Kroger Allergy Relief 25 mg 30142-0554-24 THE 12 capsules — — FDA listed —
Allergy Antihistamine 25 mg 30142-0832-48 KROGER 48 capsules — — FDA listed —
Diphenhydramine Hydrochloride 25 mg 35916-0435-01 SOFTGEL 3 capsules — — FDA listed —
Diphenhydramine Hydrochloride 25 mg 35916-0436-02 SOFTGEL 1000 capsules — — FDA listed —
Diphenhydramine Hydrochloride 25 mg 35916-0471-01 SOFTGEL 1000 capsules — — FDA listed —
TopCare Allergy Relief 25 mg 36800-0367-24 TOPCO 12 capsules — — FDA listed —
Allergy Relief 25 mg 36800-0910-01 TopCo 24 capsules — — FDA listed —
ZzzQuil Nighttime Sleep-Aid 25 mg 37000-0501-08 The 2 capsules — — FDA listed —
Allergy Medicine 25 mg 37835-0647-01 Bi-Mart 100 capsules — — FDA listed —
Allergy Relief 25 mg 41163-0613-03 United 100 capsules — — FDA listed —
Unisom SleepMinis Nighttime Sleep-Aid 25 mg 41167-0067-00 Chattem, 60 capsules — — FDA listed —
EZ Nite Sleep 25 mg 41226-0613-24 KROGER 12 capsules — — FDA listed —
Allergy Relief 25 mg 41520-0996-04 FOODHOLD 12 capsules — — FDA listed —
Allergy Relief 25 mg 42507-0313-01 HYVEE 24 capsules — — FDA listed —
Allergy Relief 25 mg 42681-0050-01 Whole 30 capsules — — FDA listed —
Nighttime sleep aid 25 mg 42829-0925-20 ASCENT 120 capsules — — Discontinued —
Allergy Relief 25 mg 49035-0901-08 Wal-Mart 24 capsules — — FDA listed —
Diphenhydramine HCL 25 mg 50090-5716-00 A-S 30 capsules — — FDA listed —
Diphenhydramine HCL 25 mg 50090-5744-01 A-S 28 capsules — — FDA listed —
Diphenhydramine Hydrochloride 25 mg 50090-7014-00 A-S 100 capsules — — FDA listed —
Benadryl Allergy Liqui-Gels 25 mg 50580-0228-24 Kenvue 12 capsules — — FDA listed —
Allergy Relief 25 mg 50804-0091-08 Geiss, 24 capsules — — FDA listed —
Diphenhydramine Hydrochloride 25 mg 51316-0347-05 CVS 120 capsules — — FDA listed —
Allergy Relief mini Softgels 25 mg 51316-0687-36 CVS 365 capsules — — FDA listed —
Nighttime Sleep-Aid Softgel 25 mg 51316-0779-24 CVS 12 capsules — — FDA listed —
Diphenhydramine Hydrochloride 25 mg 51316-0835-01 CVS 100 capsules — — FDA listed —
Allergy Relief Dye-Free Softgel 25 mg 51316-0998-22 CVS 12 capsules — — FDA listed —
Diphenhydramine HYDROCHLORIDE 25 mg 51662-1628-01 HF 2 capsules — — FDA listed —
Dormin 25 mg 52412-0100-02 Randob 2 capsules — — Discontinued —
Diphenhydramine Hydrochloride 25 mg 53345-0002-02 Humanwell 20000 capsules — — FDA listed —
Diphenhydramine Hydrochloride 25 mg 53345-0007-01 Humanwell 20000 capsules — — FDA listed —
Diphenhydramine Hydrochloride 25 mg 53345-0027-01 Humanwell 20000 capsules — — FDA listed —
Allergy 25 mg 53943-0113-01 DISCOUNT 24 capsules — — FDA listed —
Discount Drugmart Allergy Relief 25 mg 53943-0821-24 Discount 12 capsules — — FDA listed —
Diphenhydramine Hydrochloride 25 mg 54738-0115-13 Richmond 100 capsules — — FDA listed —
Diphenhydramine Hydrochloride 25 mg 55154-2344-00 Cardinal 10 capsules — — FDA listed —
Diphenhydramine HCl 25 mg 55289-0479-10 PD-Rx 10 capsules — — FDA listed —
Allergy Relief 25 mg 55301-0190-08 ARMY 24 capsules — — FDA listed —
Allergy Relief 25 mg 55910-0191-08 DOLGENCORP, 24 capsules — — FDA listed —
Allergy Relief 25 mg 55910-0752-09 DOLGENCORP 12 capsules — — FDA listed —
Complete Allergy Medicine 25 mg 57243-0190-08 Salado 24 capsules — — FDA listed —
Allergy Relief 25 mg 59640-0090-12 HEB 12 capsules — — FDA listed —
Allergy Relief 25 mg 59779-0019-22 CVS 48 capsules — — FDA listed —
Diphenhydramine Hydrochloride 25 mg 60760-0697-30 St. 30 capsules — — Discontinued —
Pharbedryl 25 mg 60760-0699-30 St. 30 capsules — — Discontinued —
Quality Choice Nighttime Sleep-Aid 25 mg 63868-0970-24 Chain 12 capsules — — FDA listed —
Allergy Relief 25 mg 63941-0413-01 VALU 24 capsules — — FDA listed —
Diphenhydramine HCL 25 mg 66424-0020-01 SDA 100 capsules — — FDA listed —
ZzzQuil 50 mg/21 66715-9746-01 Lil' 2 capsules — — FDA listed —
Allergy Relief Complete 25 mg 67091-0201-24 WinCo 24 capsules — — FDA listed —
Diphenhydramine HCL 25 mg 68071-3352-04 NuCare 4 capsules — — FDA listed —
Diphenhydramine HCl 25 mg 68071-3877-03 NuCare 30 capsules — — FDA listed —
Nighttime Sleep Aid 25 mg 68391-0613-92 BJWC 12 capsules — — FDA listed —
Diphenhydramine Hydrochloride 25 mg 68788-8855-00 Preferred 10 capsules — — FDA listed —
Diphenhydramine HCL 25 mg 68788-9687-00 Preferred 10 capsules — — FDA listed —
Allergy Relief 25 mg 68998-0113-01 Marc 24 capsules — — FDA listed —
Allergy DyeFree 25 mg 69168-0409-86 Allegiant 12 capsules — — FDA listed —
Sleep Aid 25 mg 69168-0431-86 Allegiant 12 capsules — — FDA listed —
Allergy Relief 25 mg 69452-0453-09 BIONPHARMA 12 capsules — — FDA listed —
Diphenhydramine HCl 25 mg 69618-0024-01 Reliable 100 capsules — — FDA listed —
Diphenhydramine HCl 25 mg 69842-0537-11 CVS 60 capsules — — FDA listed —
Diphenhydramine Hydrochloride 25 mg 69842-0825-00 CVS 24 capsules — — FDA listed —
GOOD REMEDIES Allergy Relief SOFTGEL 25 mg 70692-0078-22 Strive 12 capsules — — FDA listed —
RIGHT REMEDIES Allergy Relief 25 mg 70692-0832-11 Strive 1000 capsules — — FDA listed —
Diphenhydramine HCL 25 mg 71205-0615-30 Proficient 30 capsules — — FDA listed —
Diphenhydramine HCL 25 mg 71335-0352-00 Bryant 100 capsules — — FDA listed —
Diphenhydramine Hydrochloride 25 mg 71335-2257-00 Bryant 100 capsules — — FDA listed —
Diphenhydramine HCl 25 mg 71399-1027-01 Akron 100 capsules — — FDA listed —
Allergy Relief 25 mg 72036-0113-01 Harris 24 capsules — — FDA listed —
Harris Teeter Allergy Relief 25 mg 72036-0521-24 Harris 12 capsules — — FDA listed —
Allergy Relief Diphenhydramine HCl 25mg SoftGel 25 mg 72090-0052-01 Pioneer 100 capsules — — FDA listed —
Allergy Relief 25 mg 72476-0113-01 RETAIL 24 capsules — — FDA listed —
Diphenhydramine Hydrochloride 25 mg 72789-0317-10 PD-Rx 10 capsules — — FDA listed —
Allergy Relief 25 mg 73057-0348-03 Ulai 24 capsules — — FDA listed —
Diphenhydramine Hydrochloride 25 mg 73629-0007-22 AMZ789 220 capsules — — FDA listed —
Sleep Aid 25 mg 76162-0911-12 Company 12 capsules — — FDA listed —
Dye Free Allergy Relief 25 mg 76162-0914-24 Topco 12 capsules — — FDA listed —
Antihistamine 25 mg 77333-0227-10 Gendose 100 capsules — — FDA listed —
meijer NIGHTTIME Sleep Aid SOFTGEL 25 mg 79481-0779-04 Meijer, 12 capsules — — FDA listed —
Allergy Relief 25 mg 79481-0880-01 Meijer 12 capsules — — FDA listed —
Allergy Relief Dye Free 25 mg 79903-0057-24 Wal-Mart 12 capsules — — FDA listed —
Nighttime Sleep Aid 25 mg 79903-0083-01 Wal-Mart 12 capsules — — FDA listed —
Allergy Relief Dye Free 25 mg 79903-0193-48 Wal-Mart 12 capsules — — FDA listed —
Allergy Relief 25 mg 79903-0310-24 Walmart 12 capsules — — FDA listed —
equate NIGHTTIME Sleep-Aid 25 mg 79903-0400-12 WALMART 12 capsules — — FDA listed —
AXIV - VroZzz 25 mg 82706-0014-01 Vivunt 12 capsules — — FDA listed —
AXIV Allergy 25 mg 82706-0019-01 VIVUNT 12 capsules — — FDA listed —
Sleep Aid 25 mg 83059-0022-01 Shield 12 capsules — — Discontinued —
ValuRx Dye Free Allergy Relief 25 mg 83059-0080-01 Shield 12 capsules — — Discontinued —
ValuRx Dye Free Allergy Relief 25 mg 83059-0081-01 Shield 12 capsules — — Discontinued —
Sleep Aid 25 mg 83059-0115-08 Shield 8 capsules — — Discontinued —
Allergy Relief Diphenhydramine HCl 25mg SoftGel 25 mg 84324-0029-01 NUVICARE 60 capsules — — FDA listed —
Nighttime Sleep Aid 25 mg 00363-1174-24 WALGREEN 12 capsules — — FDA listed —
Sleep Aid 25 mg 83059-0075-08 Shield 8 capsules — — FDA listed —
Allergy Relief 25 mg 70000-0771-01 CARDINAL 100 capsules — — FDA listed —
About this product: other versions of the same ingredient, strength and form are listed above, least expensive first, with FDA equivalence ratings where available.
Where does this data come from?
Equivalents are other NDCs of the same ingredient, form and route from the openFDA NDC Directory, ranked least-expensive-first by NADAC. Therapeutic-equivalence (AB) ratings come from the FDA Orange Book; biologics use the FDA Purple Book for biosimilar & interchangeable status.

Availability & generic status

🏛️
2022
On the market since
Apr 2022
📍
2026
Currently FDA-listed
4 years listed
🔒
·
No generic listed yet
brand only
ℹ️No FDA-approved generic found

We did not find an FDA-approved generic match for this exact strength, form and route.

Where does this data come from?
Patents and exclusivity from the FDA Orange Book (small-molecule drugs), refreshed from public FDA data. Generic launch timing is an estimate, not a guarantee.

What it looks like

Color pink
ShapeCapsule
ImprintCPC;835
Size14 mm
ScoringNot scored
One label can cover several strengths, so colors may be combined — always confirm a loose pill against the dispensed prescription label or a pharmacist.
Where does this data come from?
Physical description (imprint, shape, color, scoring, coating) from this product’s FDA Structured Product Labeling (SPL), mirrored from DailyMed / openFDA.

Inactive Ingredients / Excipients

Inactive ingredients, also called excipients, are components of the drug product other than the active ingredient. They may include fillers, dyes, coatings, preservatives, flavors, or other formulation ingredients.

🧪 Avoiding an ingredient? See Diphenhydramine inactive ingredients by manufacturer: every current product's list side by side, so you can ask your pharmacy for the version that does not list it.

💡 Tap an ingredient (hover on desktop) to see what it is and why it’s used.

  • UNII 767IP0Y5NH
    A synthetic red colorant used to give medicines their color. It helps patients identify their medication and makes the product visually appealing.
  • UNII H3R47K3TBD
    FD&C Blue No. 1 is a synthetic blue dye approved for use in foods and medicines. It serves as a colorant to give the medication its distinctive appearance and help with product identification.
  • UNII WZB9127XOA
    A synthetic red dye used to color medications and make them easier to identify. It serves as a colorant in tablets, capsules, and liquid formulations.
  • UNII 2G86QN327L
    Gelatin is a protein derived from animal collagen, commonly used in medicines as a gelling agent and capsule material. It helps create soft or hard capsule shells that hold and release medication, and can also thicken liquid formulations.
  • UNII EWQ57Q8I5X
    Lactose monohydrate is a natural sugar derived from milk. It serves as a filler and binder in tablets and capsules, helping create the proper size, texture, and consistency of the medicine.
  • UNII 70097M6I30
    Magnesium stearate is a salt made from magnesium and stearic acid, a fatty substance. It's used in tablets and capsules as a lubricant and glidant to help ingredients flow smoothly during manufacturing and prevent sticking.
  • UNII 368GB5141J
    A detergent and foaming agent derived from coconut or palm oil. In medications, it helps break down and mix oil and water-based ingredients, aids in tablet disintegration, and improves how the drug dissolves and spreads in the mouth or digestive system.
  • UNII O8232NY3SJ
    A plant-based carbohydrate derived from corn kernels. It acts as a filler to add bulk, a binder to hold ingredients together, and a disintegrant to help the tablet break apart in your stomach for absorption.

8 inactive ingredients listed in the exact product block matched to this NDC.

The official label also statescorn starch, D&C red #28, FD&C blue #1, FD&C red #40, gelatin, lactose monohydrate, magnesium stearate, sodium lauryl sulfate

Label-section wording can be broader than the structured product block and may mention additional formulation ingredients.

Where does this data come from?
Data sourced from official FDA Structured Product Labeling (SPL) via DailyMed — ingredient classCode="IACT" elements from the exact product block matched by this NDC. Label-section narrative from DailyMed / the openFDA label index is shown separately when available.

Inactive ingredient FAQ

Are inactive ingredients the same for every manufacturer?
No. Inactive ingredients can differ by manufacturer, dosage form, strength, and package / product version.
Why might an inactive ingredient be missing?
Some SPLs do not provide a complete structured inactive-ingredient list, and older or unusual labels may only include the information in narrative text.
Can inactive ingredients matter?
Yes. They can matter for allergies, intolerances, dyes, gluten / lactose concerns, preservatives, and formulation differences — but confirm with a pharmacist or the manufacturer when it’s clinically important.

Manufacturer & labeler

LabelerMajor Pharmaceuticals
FDA applicationM012 (OTC MONOGRAPH DRUG)
Labeler code00904
First marketedApr 2022
Product typeHuman Otc Drug
Portfolio630 products on file

More NDCs from Major Pharmaceuticals labeler code 00904

The labeler markets the product; the application holder owns the FDA approval. They’re often the same company but can differ (e.g. a repackager or an authorized generic). A mailing address / phone appears here when the manufacturer includes it in the product’s FDA label (not all do).
Where does this data come from?
Labeler, application holder and registered establishment from the FDA openFDA NDC Directory and Drugs@FDA; address/contact from the product’s FDA label.

FDA label — Drug Facts FDA SPL

The complete FDA label for this product — the official Drug Facts labeling, verbatim, section by section. Jump with a chip, search within the label, or expand everything.
🎯 Indications and Usage ⏱️ Dosage and Administration ⚠️ Warnings 🆘 Overdosage 🧪 Active Ingredient 🧪 Inactive Ingredients 🎯 Purpose 📄 Do Not Use 📄 Ask a Doctor Before Use If 📄 Ask a Doctor or Pharmacist Before Use If 📄 When Using This Product 🤰 If Pregnant or Breast-Feeding 📄 Keep Out of Reach of Children 📄 Other Information 📄 Questions or Comments 📄 Package Label / Principal Display Panel
🎯 Indications and Usage 46 words ▾

Uses  temporarily relieves these symptoms due to hay fever or other upper respiratory allergies:  runny nose  sneezing  itchy, watery eyes  itching of the nose or throat  temporarily relieves these symptoms due to the common cold:  runny nose  sneezing

⏱️ Dosage and Administration 66 words ▾

Directions  take every 4 to 6 hours, or as directed by a doctor  do not take more than 6 doses in 24 hours adults and children 12 years of age and over 1 to 2 capsules children 6 to under 12 years of age 1 capsule children under 6 years of age do not use this product in children under 6 years of age

⚠️ Warnings 133 words ▾

 to make a child sleepy  with any other product containing diphenhydramine, even one used on skin Ask a doctor before use if you have  a breathing problem such as emphysema or chronic bronchitis  glaucoma  trouble urinating due to an enlarged prostate gland Ask a doctor or pharmacist before use if you are taking sedatives or tranquilizers When using this product  marked drowsiness may occur  avoid alcoholic drinks  alcohol, sedatives and tranquilizers may increase drowsiness  be careful when driving a motor vehicle or operating machinery  excitability may occur, especially in children If pregnant or breast-feeding , ask a health professional before use.

Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center right away (1-800-222-1222).

🆘 Overdosage 16 words ▾

In case of overdose, get medical help or contact a Poison Control Center right away (1-800-222-1222).

🧪 Active Ingredient 11 words ▾

Drug Facts Active ingredient (in each capsule) Diphenhydramine HCl 25 mg

🧪 Inactive Ingredients 19 words ▾

corn starch, D&C red #28, FD&C blue #1, FD&C red #40, gelatin, lactose monohydrate, magnesium stearate, sodium lauryl sulfate

🎯 Purpose 2 words ▾

Purpose Antihistamine

📄 Do Not Use 18 words ▾

 to make a child sleepy  with any other product containing diphenhydramine, even one used on skin

📄 Ask a Doctor Before Use If 29 words ▾

Ask a doctor before use if you have  a breathing problem such as emphysema or chronic bronchitis  glaucoma  trouble urinating due to an enlarged prostate gland

📄 Ask a Doctor or Pharmacist Before Use If 14 words ▾

Ask a doctor or pharmacist before use if you are taking sedatives or tranquilizers

📄 When Using This Product 39 words ▾

When using this product  marked drowsiness may occur  avoid alcoholic drinks  alcohol, sedatives and tranquilizers may increase drowsiness  be careful when driving a motor vehicle or operating machinery  excitability may occur, especially in children

🤰 If Pregnant or Breast-Feeding 11 words ▾

If pregnant or breast-feeding , ask a health professional before use.

📄 Keep Out of Reach of Children 6 words ▾

Keep out of reach of children.

📄 Other Information 15 words ▾

Other information  store in a dry place at 15° – 30°C (59° – 86°F)

📄 Questions or Comments 4 words ▾

Questions or comments? 1-800-616-2471

📄 Package Label / Principal Display Panel 43 words ▾

Major BENOPHEN NDC 0904-7237-24 Diphenhydramin HCl 25 mg Antihistamine For the temporary relief of the symptoms of: • Upper Respiratory Allergies • Hay Fever Compare to the active ingredient in BENADRYL® Allergy* 24 CAPSULES EACH CAPSULE INDIVIDUALLY BANDED FOR YOUR PROTECTION Major Label

Source: FDA Structured Product Labeling, mirrored from DailyMed / openFDA. Prefer the government’s original formatting? View this label on DailyMed ↗

Medicaid utilization & spend

📍 This exact package only: Medicaid data is reported per full 11-digit NDC — labeler, product and pack size — so every number here is for this package alone, not the drug overall. Other pack sizes report separately.
💊 Pharmacy benefit only: These are Medicaid outpatient pharmacy claims, billed by NDC. They exclude the medical benefit — clinic- or hospital-administered drugs billed under HCPCS J-codes — so drugs used mostly that way (e.g. Avastin, Lucentis, Keytruda) can look low or missing here. That’s expected, not an error.
📅 Q1 2025 – Q1 2026 · 5 quarters of data
ⓘ The newest quarter is usually incomplete when first published; states restate recent quarters in later CMS releases, so the latest figures typically revise upward. State coverage-policy changes can also shift quarter-to-quarter totals.
Prescriptions last 4 qtrs
74.9K
Units reimbursed last 4 qtrs
2.9M
Gross reimbursed last 4 qtrs
$463.2K
Avg / prescription
$6.19
Avg / unit
$0.1589
Latest quarter Q1 2026
6.3KRx
Medicaid pays / ea
$0.1589
gross reimbursed
vs
NADAC / ea
$0.0534
acquisition cost
=
Spread
+$0.1055
+198% vs cost
What Medicaid paid per ea (before rebates; includes the pharmacy’s dispensing fee) compared with NADAC — the average price pharmacies pay to buy the drug. A positive spread means Medicaid reimbursed more than the purchase price, before manufacturer rebates.
Fee-for-service vs managed care ⓘ
38% FFS 62% MCO
Fee-for-service · 28,540 Rx Managed care · 46,324 Rx
State Medicaid map
Alaska: no data reported AK Maine: 23,221 units · 1,665 per 100k residents ME Washington: 82,543 units · 1,057 per 100k residents WA Idaho: no data reported ID Montana: 7,193 units · 635 per 100k residents MT North Dakota: no data reported ND Minnesota: 115,118 units · 2,007 per 100k residents MN Wisconsin: 93,367 units · 1,580 per 100k residents WI Michigan: 173,284 units · 1,726 per 100k residents MI New York: 477,154 units · 2,438 per 100k residents NY Vermont: no data reported VT New Hampshire: 6,179 units · 441 per 100k residents NH Oregon: 72,806 units · 1,720 per 100k residents OR Nevada: 41,614 units · 1,303 per 100k residents NV Wyoming: 433 units · 74.1 per 100k residents WY South Dakota: 254 units · 27.6 per 100k residents SD Iowa: 33,390 units · 1,041 per 100k residents IA Illinois: 73,887 units · 589 per 100k residents IL Indiana: 79,915 units · 1,165 per 100k residents IN Ohio: 268,600 units · 2,279 per 100k residents OH Pennsylvania: 241,334 units · 1,862 per 100k residents PA New Jersey: 55,844 units · 601 per 100k residents NJ Massachusetts: 183,449 units · 2,620 per 100k residents MA California: 46,493 units · 119 per 100k residents CA Utah: 9,157 units · 268 per 100k residents UT Colorado: no data reported CO Nebraska: 25,093 units · 1,269 per 100k residents NE Missouri: 89,064 units · 1,437 per 100k residents MO Kentucky: 124,254 units · 2,745 per 100k residents KY West Virginia: 21,791 units · 1,231 per 100k residents WV Virginia: 64,948 units · 745 per 100k residents VA Maryland: 36,269 units · 587 per 100k residents MD Connecticut: 30,499 units · 843 per 100k residents CT Rhode Island: 30,941 units · 2,826 per 100k residents RI Arizona: 85,684 units · 1,153 per 100k residents AZ New Mexico: 2,848 units · 135 per 100k residents NM Kansas: 17,194 units · 585 per 100k residents KS Arkansas: 7,520 units · 245 per 100k residents AR Tennessee: 999 units · 14.0 per 100k residents TN North Carolina: no data reported NC South Carolina: 18,568 units · 346 per 100k residents SC Delaware: no data reported DE Oklahoma: no data reported OK Louisiana: no data reported LA Mississippi: 16,270 units · 553 per 100k residents MS Alabama: no data reported AL Georgia: 75,441 units · 684 per 100k residents GA D.C.: 14,464 units · 2,130 per 100k residents DC Hawaii: 31,559 units · 2,199 per 100k residents HI Texas: 136,480 units · 447 per 100k residents TX Florida: no data reported FL
Units reimbursed · per 100k residents
14.02,826
gray = no data reported ⓘ
Colors are per 100,000 residents, so big states don’t automatically dominate. Tap or hover a state for its actual totals.
Tap or hover a state
…for its Medicaid breakdown
🏆 Top states by units · per 100k residents
1 Rhode Island 2,826 /100k
2 Kentucky 2,745 /100k
3 Massachusetts 2,620 /100k
4 New York 2,438 /100k
5 Ohio 2,279 /100k
6 Hawaii 2,199 /100k
7 D.C. 2,130 /100k
8 Minnesota 2,007 /100k
National units — by quarter
💵 About the dollar figures: “reimbursed” is what Medicaid paid pharmacies before confidential manufacturer rebates, so the program’s real net cost is lower than these numbers. Fee-for-service and managed-care claims are combined unless split above. Source: CMS State Drug Utilization Data; per-100k rates use 2023 Census population estimates.

Medicaid utilization by pack size

Medicaid (SDUD) totals over the four most recent reported quarters for every package size of this drug — handy when a specific package (e.g. a starter/titration pack) carries little or no Medicaid volume on its own.
1000 capsules00904-7237-80 90,030 Rx · $846,733
100 capsules this page00904-7237-60 74,864 Rx · $463,175
100 capsules00904-7237-61 22,712 Rx · $848,732
24 capsules00904-7237-24 9,970 Rx · $136,960
Drug total (last 4 qtrs): 197,576 Rx · 7,417,484 units · $2,295,600 gross reimbursed
Tap a pack size to open its page. Source: CMS State Drug Utilization Data, last 4 quarters.
← 00904-7236-61 · Major 00904-7243-61 · Major →
For educational and professional reference only — not medical advice. Pricing reflects published NADAC and CMS ASP (free public data) and may differ from your acquisition cost; always verify before billing or dispensing.