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Acetaminophen 325 MG / doxylamine succinate 6.25 MG / phenylephrine hydrochloride 5 MG Ora... — RxCUI 1052647

RxNorm drug concept · Semantic clinical drug
RxCUI 1052647 Semantic clinical drug · SCD ● Current RxNorm concept 2 FDA products 2 package NDCs Snapshot Jul 14, 2026

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Compiled from public NLM RxNorm and FDA (openFDA NDC directory) data sources. Editorial policy

What you’re looking at: the standardized identity of one medicine, as the U.S. drug-data system sees it. Below — every FDA-listed product, package code, price benchmark, and billing code that maps to it.

🗂️ Key Facts

RxCUI1052647
Official nameAcetaminophen 325 MG / doxylamine succinate 6.25 MG / phenylephrine hydrochloride 5 MG Oral Capsule
Concept typeSemantic clinical drug (SCD)
RxNorm statusCurrent RxNorm concept
Also known asAPAP 325 MG / doxylamine succinate 6.25 MG / Phenylephrine Hydrochloride 5 MG Oral Capsule; acetaminophen 325 MG / doxylamine succinate 6.25 MG / phenylephrine HCl 5 MG Oral Capsule
FDA products mapped2
Package NDCs mapped2
RxNorm release07/06/2026
Snapshot dataJul 14, 2026

📖 Skip the Codes — Read It in Plain English.

Our pharmacist-built guide to Phenylephrine: what it is, how it’s used, side effects, and interactions.

📗 Our plain-language guide HelloPharmacist
  • It depends on the product. The injection raises low blood pressure during anesthesia and, for some products, septic shock. Eye drops dilate the pupil, nasal products relieve conges...
  • Be careful. Over-the-counter phenylephrine should not be used with a prescription MAOI or within 2 weeks of stopping one. If you aren't sure whether your medicine is an MAOI, ask m...
  • With the injection, the most common are nausea, vomiting and headache. Call for help right away if you have chest pain, a very slow heartbeat, or pain or skin changes around the IV...
  • Stop and talk to a doctor if you get nervousness, dizziness or sleeplessness. Also stop if symptoms last more than 7 days or come with a fever. Don't use more than the label recomm...
📖 Read our full Phenylephrine guide →

🕸️ Concept Web — How Acetaminophen 325 MG / doxylamine succinate 6.25... Connects

One RxCUI never lives alone. Follow the path from the raw ingredient down to the exact strength-and-form concepts FDA products carry — every stop is a real RxNorm concept with its own identifier. Hover or focus any chip for what it means.
This page's concept Acetaminophen 325 MG / doxylamine succinate 6.25 MG / phenylephrine hydrochloride 5 MG Oral Capsule RxCUI 1052647

Every web starts here: one RxCUI, one fixed meaning in the RxNorm vocabulary.

  1. Ingredients 6

    The active substance itself — no strength, form, or brand attached yet.

    • Acetaminophen 161
    • Doxylamine 3642
    • Phenylephrine 8163
    • Acetaminophen / doxylamine / phenylephrine 1006887
    • Doxylamine succinate 23665
    • Phenylephrine hydrochloride 8164
  2. Dose forms 9

    The ingredient poured into a form — tablet, solution, cream — still without one fixed strength.

    • Acetaminophen / doxylamine / phenylephrine Oral Capsule 685047
    • Acetaminophen / doxylamine succinate / phenylephrine hydrochloride Oral Capsule 2647334
    • Acetaminophen / doxylamine / phenylephrine Oral Product 1151211
    • Acetaminophen / doxylamine / phenylephrine Pill 1151212
    • Acetaminophen / doxylamine succinate / phenylephrine hydrochloride Oral Product 2661656
    • Acetaminophen / doxylamine succinate / phenylephrine hydrochloride Pill 2661918
    • Oral Capsule 316965
    • Oral Product 1151131
    • +1 more in this family
  3. Clinical & branded drugs 3

    Ingredient + strength + dose form. These are the concepts real FDA products actually carry.

    • Acetaminophen 325 MG 315263
    • Doxylamine succinate 6.25 MG 1052646
    • Phenylephrine hydrochloride 5 MG 1020198
  4. Packs 1

    Fixed collections of drugs packaged and sold together, like dose packs.

    • {1 (acetaminophen 325 MG / doxylamine succinate 6.25 MG / phenylephrine hydrochloride 5 MG Oral Capsule) / 1 (acetaminophen 325 MG / phenylephrine hydrochloride 5 MG Oral Capsule) } Pack 2634822

Showing up to 8 concepts per family — 18 of 19 stored related concepts drawn.
These are official RxNorm vocabulary relationships — how concepts name and organize the same medicine. They do not establish therapeutic equivalence or substitutability: two concepts appearing in one web is never a statement that products can be swapped.

🔀 Generic ⇄ Brand Crosswalk

The same medicine has an unbranded (generic) identity and one or more brand-name identities — each with its own RxCUI. This is a naming relationship in RxNorm, not a statement that any two products are substitutable.

Generic (Clinical) Concepts

  • Acetaminophen 325 MG SCDC · 315263
  • Doxylamine succinate 6.25 MG SCDC · 1052646
  • Phenylephrine hydrochloride 5 MG SCDC · 1020198
  • Acetaminophen / doxylamine / phenylephrine Oral Capsule SCDF · 685047
  • Acetaminophen / doxylamine succinate / phenylephrine hydrochloride Oral Capsule SCDFP · 2647334
  • Acetaminophen / doxylamine / phenylephrine Oral Product SCDG · 1151211
  • Acetaminophen / doxylamine / phenylephrine Pill SCDG · 1151212
  • Acetaminophen / doxylamine succinate / phenylephrine hydrochloride Oral Product SCDGP · 2661656
  • Acetaminophen / doxylamine succinate / phenylephrine hydrochloride Pill SCDGP · 2661918
  • {1 (acetaminophen 325 MG / doxylamine succinate 6.25 MG / phenylephrine hydrochloride 5 MG Oral Capsule) / 1 (acetaminophen 325 MG / phenylephrine hydrochloride 5 MG Oral Capsule) } Pack GPCK · 2634822

📦 FDA Products & Package NDCs

2 products · 2 package NDCs
2 package NDCs map to RxCUI 1052647 in the current snapshot — up to 50 per page. Each linked NDC opens its full package page.
Package NDC Package Brand / generic name Labeler Marketing start
53345-0013-01 1 BAG in 1 BOX (53345-013-01) / 4000 CAPSULE, LIQUID FILLED... NightTime Sinus Relief Humanwell PuraCap Pharmaceutical (Wuhan), Ltd. 2013-06-15
53345-0031-01 1 BAG in 1 BOX (53345-031-01) / 4000 CAPSULE, LIQUID FILLED... NightTime Sinus Humanwell PuraCap Pharmaceutical (Wuhan) Co., Ltd. 2015-02-26
Observed labelers: Humanwell PuraCap Pharmaceutical (Wuhan) Co., Ltd. (1) · Humanwell PuraCap Pharmaceutical (Wuhan), Ltd. (1) — this is the FDA-listed mapping footprint, not sales, inventory, availability, or market share.

🗃️ Sources & Limits

Atlas generation902fddb9-e9c1-4004-bf4c-dba4d51037c7
openFDA export observedJul 14, 2026
RxNorm release07/06/2026
Methodology2026-07-full-catalog-v1
  • A shared RxCUI does not prove interchangeability. Products mapped to the same concept are not thereby equivalent or substitutable — equivalence is a separate, product-level determination.
  • Listing here does not establish approval or coverage. Appearing in this snapshot is a data observation, not an FDA approval status or a payer coverage decision.
  • Missing data never means zero. A silent dataset (no price, no billing code, no utilization) means no observation — not that the real-world value is zero.
  • Counts describe the mapping footprint. Product, package, and labeler counts are the FDA-listed mapping footprint in this snapshot — not sales, inventory, availability, or market share.
This product uses publicly available data from the U.S. National Library of Medicine (NLM), National Institutes of Health, Department of Health and Human Services; NLM is not responsible for the product and does not endorse or recommend this or any other product.

Machine-readable JSON

Reference information about drug-concept identifiers and public regulatory data — not medical advice. Talk to your pharmacist or prescriber about your own medication.