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Acetaminophen 325 MG / chlorpheniramine maleate 2 MG / dextromethorphan hydrobromide 10 MG... — RxCUI 1086991

RxNorm drug concept · Semantic clinical drug
RxCUI 1086991 Semantic clinical drug · SCD ● Current RxNorm concept 30 FDA products 33 package NDCs Snapshot Jul 14, 2026

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Compiled from public NLM RxNorm and FDA (openFDA NDC directory) data sources. Editorial policy

What you’re looking at: the standardized identity of one medicine, as the U.S. drug-data system sees it. Below — every FDA-listed product, package code, price benchmark, and billing code that maps to it.

🗂️ Key Facts

RxCUI1086991
Official nameAcetaminophen 325 MG / chlorpheniramine maleate 2 MG / dextromethorphan hydrobromide 10 MG / phenylephrine hydrochloride 5 MG Oral Tablet
Concept typeSemantic clinical drug (SCD)
RxNorm statusCurrent RxNorm concept
Also known asAPAP 325 MG / chlorpheniramine maleate 2 MG / dextromethorphan hydrobromide 10 MG / phenylephrine hydrochloride 5 MG Oral Tablet; acetaminophen 325 MG / chlorpheniramine maleate 2 MG / dextromethorphan HBr 10 MG / phenylephrine HCl 5 MG Oral Tablet
FDA products mapped30
Package NDCs mapped33
RxNorm release07/06/2026
Snapshot dataJul 14, 2026

📖 Skip the Codes — Read It in Plain English.

Our pharmacist-built guide to Phenylephrine: what it is, how it’s used, side effects, and interactions.

📗 Our plain-language guide HelloPharmacist
  • Yes, it's the same active ingredient, but used in very different ways depending on the form. The nasal spray delivers a tiny amount directly to the nasal lining to temporarily shri...
  • I see phenylephrine in nasal sprays at the pharmacy AND as an IV drug in the hospital — is it really the same medication?
  • You should check with your doctor first. Phenylephrine constricts blood vessels, which can raise blood pressure and put extra strain on the heart — even from a nasal spray. If you...
  • Can I use the nasal spray if I have high blood pressure or heart disease?
📖 Read our full Phenylephrine guide →

🕸️ Concept Web — How Acetaminophen 325 MG / chlorpheniramine maleate... Connects

One RxCUI never lives alone. Follow the path from the raw ingredient down to the exact strength-and-form concepts FDA products carry — every stop is a real RxNorm concept with its own identifier. Hover or focus any chip for what it means.
This page's concept Acetaminophen 325 MG / chlorpheniramine maleate 2 MG / dextromethorphan hydrobromide 10 MG / phenylephrine hydrochloride 5 MG Oral Tablet RxCUI 1086991

Every web starts here: one RxCUI, one fixed meaning in the RxNorm vocabulary.

  1. Ingredients 8

    The active substance itself — no strength, form, or brand attached yet.

    • Acetaminophen 161
    • Chlorpheniramine 2400
    • Dextromethorphan 3289
    • Phenylephrine 8163
    • Acetaminophen / chlorpheniramine / dextromethorphan / phenylephrine 689580
    • Chlorpheniramine maleate 142429
    • Dextromethorphan hydrobromide 102490
    • Phenylephrine hydrochloride 8164
  2. Dose forms 9

    The ingredient poured into a form — tablet, solution, cream — still without one fixed strength.

    • Acetaminophen / chlorpheniramine / dextromethorphan / phenylephrine Oral Tablet 644179
    • Acetaminophen / chlorpheniramine maleate / dextromethorphan hydrobromide / phenylephrine hydrochloride Oral Tablet 2646156
    • Acetaminophen / chlorpheniramine / dextromethorphan / phenylephrine Oral Product 1154903
    • Acetaminophen / chlorpheniramine / dextromethorphan / phenylephrine Pill 1154904
    • Acetaminophen / chlorpheniramine maleate / dextromethorphan hydrobromide / phenylephrine hydrochloride Oral Product 2659525
    • Acetaminophen / chlorpheniramine maleate / dextromethorphan hydrobromide / phenylephrine hydrochloride Pill 2663439
    • Oral Tablet 317541
    • Oral Product 1151131
    • +1 more in this family
  3. Clinical & branded drugs 4

    Ingredient + strength + dose form. These are the concepts real FDA products actually carry.

    • Acetaminophen 325 MG 315263
    • Chlorpheniramine maleate 2 MG 999433
    • Dextromethorphan hydrobromide 10 MG 1014455
    • Phenylephrine hydrochloride 5 MG 1020198
  4. Packs 2

    Fixed collections of drugs packaged and sold together, like dose packs.

Showing up to 8 concepts per family — 22 of 23 stored related concepts drawn.
These are official RxNorm vocabulary relationships — how concepts name and organize the same medicine. They do not establish therapeutic equivalence or substitutability: two concepts appearing in one web is never a statement that products can be swapped.

🔀 Generic ⇄ Brand Crosswalk

The same medicine has an unbranded (generic) identity and one or more brand-name identities — each with its own RxCUI. This is a naming relationship in RxNorm, not a statement that any two products are substitutable.

Generic (Clinical) Concepts

📦 FDA Products & Package NDCs

30 products · 33 package NDCs
33 package NDCs map to RxCUI 1086991 in the current snapshot — up to 50 per page. Each linked NDC opens its full package page.
Package NDC Package Brand / generic name Labeler Marketing start
11822-5034-08 1 KIT in 1 CARTON (11822-5034-8) * 8 TABLET, FILM COATED i... Cold and Flu Severe, Daytime, Nighttime Rite Aid Corporation 2021-06-30
36800-0250-56 1 KIT in 1 CARTON (36800-250-56) * 12 TABLET, COATED in 1... Cold Relief Multi-Symptom TopCare 2011-10-01
36800-0914-02 2 BLISTER PACK in 1 CARTON (36800-914-02) / 12 TABLET, COAT... Cold Max Nighttime TopCo Associates LLC 2011-08-30
36800-0925-02 2 BLISTER PACK in 1 CARTON (36800-925-02) / 12 TABLET, COAT... Cold Plus Head Congestion Nighttime TopCo Associates LLC 2011-08-30
36800-0927-02 1 KIT in 1 CARTON (36800-927-02) * 12 TABLET, COATED in 1... Cold Plus Head Congestion Day and Night TopCo Associates LLC 2011-08-30
37808-0286-01 1 KIT in 1 CARTON (37808-286-01) * 8 TABLET, COATED in 1 B... Cold Flu Severe Day Night HEB 2018-03-01
41163-0529-08 1 KIT in 1 CARTON (41163-529-08) * 12 TABLET, FILM COATED... Daytime Cold, Nighttime Cold multi-symptom United Natural Foods, Inc. dba UNFI 2005-07-21
46122-0411-62 1 KIT in 1 CARTON (46122-411-62) * 12 TABLET, COATED in 1... Cold Max Day and Night AmeriSource Bergen 2018-08-01
49035-0931-08 1 KIT in 1 CARTON (49035-931-08) * 12 TABLET, FILM COATED... Cold Multi-Symptom Wal-Mart Stores Inc 2005-07-21
50580-0414-03 3 CARTON in 1 CELLO PACK (50580-414-03) / 1 KIT in 1 CARTON... TYLENOL COLD PLUS FLU SEVERE DAY/NIGHT Kenvue Brands LLC 2016-07-18
50580-0414-04 1 KIT in 1 CARTON (50580-414-04) * 2 BLISTER PACK in 1 CAR... TYLENOL COLD PLUS FLU SEVERE DAY/NIGHT Kenvue Brands LLC 2018-12-21
50804-0551-02 1 KIT in 1 CARTON (50804-551-02) * 12 TABLET, COATED in 1... Cold Multi-Symptom Daytime and Nighttime GoodSense 2011-12-31
50844-0529-09 1 KIT in 1 CARTON (50844-529-09) * 12 TABLET, FILM COATED... Cold Relief Multi-Symptom L.N.K. International, Inc. 2005-07-21
50844-0547-08 1 KIT in 1 CARTON (50844-547-08) * 8 TABLET, FILM COATED i... Cold and Flu Severe, Day, Night L.N.K. International, Inc. 2021-07-15
51316-0509-08 1 KIT in 1 CARTON (51316-509-08) * 8 TABLET, FILM COATED i... Severe Cold and Flu Daytime, Nighttime CVS WOONSOCKET PRESCRIPTION CENTER, INCORPORATED 2026-03-06
51467-0007-01 2 BLISTER PACK in 1 BOX (51467-007-01) / 12 TABLET in 1 BLI... COLTALIN-DM FORTUNE PHARMACAL COMPANY LIMITED 2026-01-30
51467-0007-02 3 BLISTER PACK in 1 BOX (51467-007-02) / 12 TABLET in 1 BLI... COLTALIN-DM FORTUNE PHARMACAL COMPANY LIMITED 2026-01-30
51467-0012-01 2 BLISTER PACK in 1 BOX (51467-012-01) / 12 TABLET in 1 BLI... COLTALIN-DM FORTUNE PHARMACAL COMPANY LIMITED 2026-01-30
51467-0012-02 3 BLISTER PACK in 1 BOX (51467-012-02) / 12 TABLET in 1 BLI... COLTALIN-DM FORTUNE PHARMACAL COMPANY LIMITED 2026-01-30
53943-0186-01 1 KIT in 1 CARTON (53943-186-01) * 8 TABLET, COATED in 1 B... COLD AND FLU SEVERE DISCOUNT DRUG MART 2019-05-01
53943-0239-02 2 BLISTER PACK in 1 CARTON (53943-239-02) / 12 TABLET, COAT... Cold Max Nighttime DISCOUNT DRUG MART 2022-08-03
55301-0547-08 2 BLISTER PACK in 1 CARTON (55301-547-08) / 1 KIT in 1 BLIS... Cold and Flu Day and Night, Severe ARMY AND AIR FORCE EXCHANGE SERVICE 2023-03-31
55910-0573-08 1 KIT in 1 CARTON (55910-573-08) * 8 TABLET, FILM COATED i... Cold and Flu Severe Day Time / Night Time DOLGENCORP, LLC 2005-08-04
63868-0015-20 1 KIT in 1 CARTON (63868-015-20) * 12 TABLET, COATED in 1... Cold Multi Symptom Daytime Nighttime Chain Drug Marketing Association 2013-03-06
63941-0473-08 2 BLISTER PACK in 1 CARTON (63941-473-08) / 12 TABLET, FILM... Multi-Symptom Cold Valu Merchandisers Company 2005-07-21
68998-0139-02 2 BLISTER PACK in 1 CARTON (68998-139-02) / 12 TABLET, COAT... Cold Multi-Symptom Nighttime Marc Glassman, Inc. 2010-01-27
69168-0319-86 12 TABLET in 1 BLISTER PACK (69168-319-86) Cold Multi-Symptom Night-time Allegiant Health 2014-12-23
69842-0803-08 1 KIT in 1 CARTON (69842-803-08) * 8 TABLET, FILM COATED i... Severe Cold and Flu Relief Daytime/Nighttime CVS PHARMACY 2005-08-04
72036-0186-01 1 KIT in 1 CARTON (72036-186-01) * 8 TABLET, COATED in 1 B... Cold Flu Severe Day Night Harris Teeter 2019-09-23
72476-0239-02 2 BLISTER PACK in 1 CARTON (72476-239-02) / 12 TABLET, COAT... Cold Max Nighttime RETAIL BUSINESS SERVICES , LLC. 2022-10-25
79481-5034-08 2 BLISTER PACK in 1 CARTON (79481-5034-8) / 1 KIT in 1 BLIS... COLD AND FLU SEVERE Daytime, Nighttime Meijer Distribution, Inc. 2024-11-08
83324-0092-24 1 KIT in 1 CARTON (83324-092-24) * 8 TABLET, COATED in 1 B... Cold and Flu Severe Day and Night CHAIN DRUG MARKETING ASSOCIATION, INC 2024-07-18
83324-0093-20 1 KIT in 1 CARTON (83324-093-20) * 12 TABLET, COATED in 1... Cold Max Day and NIght CHAIN DRUG MARKETING ASSOCIATION, INC. 2024-08-07
Observed labelers: FORTUNE PHARMACAL COMPANY LIMITED (4) · TopCo Associates LLC (3) · DISCOUNT DRUG MART (2) · Kenvue Brands LLC (2) · L.N.K. International, Inc. (2) · Allegiant Health (1) · +19 more — this is the FDA-listed mapping footprint, not sales, inventory, availability, or market share.

🗃️ Sources & Limits

Atlas generation902fddb9-e9c1-4004-bf4c-dba4d51037c7
openFDA export observedJul 14, 2026
RxNorm release07/06/2026
Methodology2026-07-full-catalog-v1
  • A shared RxCUI does not prove interchangeability. Products mapped to the same concept are not thereby equivalent or substitutable — equivalence is a separate, product-level determination.
  • Listing here does not establish approval or coverage. Appearing in this snapshot is a data observation, not an FDA approval status or a payer coverage decision.
  • Missing data never means zero. A silent dataset (no price, no billing code, no utilization) means no observation — not that the real-world value is zero.
  • Counts describe the mapping footprint. Product, package, and labeler counts are the FDA-listed mapping footprint in this snapshot — not sales, inventory, availability, or market share.
This product uses publicly available data from the U.S. National Library of Medicine (NLM), National Institutes of Health, Department of Health and Human Services; NLM is not responsible for the product and does not endorse or recommend this or any other product.

Machine-readable JSON

Reference information about drug-concept identifiers and public regulatory data — not medical advice. Talk to your pharmacist or prescriber about your own medication.