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Dextromethorphan hydrobromide 4 MG/ML / guaifenesin 80 MG/ML / phenylephrine hydrochloride... — RxCUI 1091331

RxNorm drug concept · Semantic clinical drug
RxCUI 1091331 Semantic clinical drug · SCD ● Current RxNorm concept 5 FDA products 7 package NDCs Snapshot Jul 14, 2026

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Compiled from public NLM RxNorm and FDA (openFDA NDC directory) data sources. Editorial policy

What you’re looking at: the standardized identity of one medicine, as the U.S. drug-data system sees it. Below — every FDA-listed product, package code, price benchmark, and billing code that maps to it.

🗂️ Key Facts

RxCUI1091331
Official nameDextromethorphan hydrobromide 4 MG/ML / guaifenesin 80 MG/ML / phenylephrine hydrochloride 2 MG/ML Oral Solution
Concept typeSemantic clinical drug (SCD)
RxNorm statusCurrent RxNorm concept
Also known asdextromethorphan hydrobromide 20 MG / guaifenesin 400 MG / phenylephrine hydrochloride 10 MG per 5 ML Oral Solution; dextromethorphan HBr 20 MG / guaiFENesin 400 MG / phenylephrine HCl 10 MG in 5 mL Oral Solution
FDA products mapped5
Package NDCs mapped7
RxNorm release07/06/2026
Snapshot dataJul 14, 2026

📖 Skip the Codes — Read It in Plain English.

Our pharmacist-built guide to Phenylephrine: what it is, how it’s used, side effects, and interactions.

📗 Our plain-language guide HelloPharmacist
  • Yes, it's the same active ingredient, but used in very different ways depending on the form. The nasal spray delivers a tiny amount directly to the nasal lining to temporarily shri...
  • I see phenylephrine in nasal sprays at the pharmacy AND as an IV drug in the hospital — is it really the same medication?
  • You should check with your doctor first. Phenylephrine constricts blood vessels, which can raise blood pressure and put extra strain on the heart — even from a nasal spray. If you...
  • Can I use the nasal spray if I have high blood pressure or heart disease?
📖 Read our full Phenylephrine guide →

🕸️ Concept Web — How Dextromethorphan hydrobromide 4 MG/ML / guaifene... Connects

One RxCUI never lives alone. Follow the path from the raw ingredient down to the exact strength-and-form concepts FDA products carry — every stop is a real RxNorm concept with its own identifier. Hover or focus any chip for what it means.
This page's concept Dextromethorphan hydrobromide 4 MG/ML / guaifenesin 80 MG/ML / phenylephrine hydrochloride 2 MG/ML Oral Solution RxCUI 1091331

Every web starts here: one RxCUI, one fixed meaning in the RxNorm vocabulary.

  1. Ingredients 6

    The active substance itself — no strength, form, or brand attached yet.

    • Dextromethorphan 3289
    • Guaifenesin 5032
    • Phenylephrine 8163
    • Dextromethorphan / guaifenesin / phenylephrine 214494
    • Dextromethorphan hydrobromide 102490
    • Phenylephrine hydrochloride 8164
  2. Dose forms 9

    The ingredient poured into a form — tablet, solution, cream — still without one fixed strength.

    • Dextromethorphan / guaifenesin / phenylephrine Oral Solution 375427
    • Dextromethorphan hydrobromide / guaifenesin / phenylephrine hydrochloride Oral Solution 2645876
    • Dextromethorphan / guaifenesin / phenylephrine Oral Liquid Product 1154857
    • Dextromethorphan / guaifenesin / phenylephrine Oral Product 1154858
    • Dextromethorphan hydrobromide / guaifenesin / phenylephrine hydrochloride Oral Liquid Product 2663136
    • Dextromethorphan hydrobromide / guaifenesin / phenylephrine hydrochloride Oral Product 2663549
    • Oral Solution 316968
    • Oral Liquid Product 1151137
    • +1 more in this family
  3. Clinical & branded drugs 3

    Ingredient + strength + dose form. These are the concepts real FDA products actually carry.

    • Dextromethorphan hydrobromide 4 MG/ML 1010978
    • Guaifenesin 80 MG/ML 331795
    • Phenylephrine hydrochloride 2 MG/ML 996626

Showing up to 8 concepts per family — 17 of 18 stored related concepts drawn.
These are official RxNorm vocabulary relationships — how concepts name and organize the same medicine. They do not establish therapeutic equivalence or substitutability: two concepts appearing in one web is never a statement that products can be swapped.

🔀 Generic ⇄ Brand Crosswalk

The same medicine has an unbranded (generic) identity and one or more brand-name identities — each with its own RxCUI. This is a naming relationship in RxNorm, not a statement that any two products are substitutable.

Generic (Clinical) Concepts

  • Dextromethorphan hydrobromide 4 MG/ML SCDC · 1010978
  • Guaifenesin 80 MG/ML SCDC · 331795
  • Phenylephrine hydrochloride 2 MG/ML SCDC · 996626
  • Dextromethorphan / guaifenesin / phenylephrine Oral Solution SCDF · 375427
  • Dextromethorphan hydrobromide / guaifenesin / phenylephrine hydrochloride Oral Solution SCDFP · 2645876
  • Dextromethorphan / guaifenesin / phenylephrine Oral Liquid Product SCDG · 1154857
  • Dextromethorphan / guaifenesin / phenylephrine Oral Product SCDG · 1154858
  • Dextromethorphan hydrobromide / guaifenesin / phenylephrine hydrochloride Oral Liquid Product SCDGP · 2663136
  • Dextromethorphan hydrobromide / guaifenesin / phenylephrine hydrochloride Oral Product SCDGP · 2663549

📦 FDA Products & Package NDCs

5 products · 7 package NDCs
7 package NDCs map to RxCUI 1091331 in the current snapshot — up to 50 per page. Each linked NDC opens its full package page.
Package NDC Package Brand / generic name Labeler Marketing start
45737-0249-16 473 mL in 1 BOTTLE (45737-249-16) Biocof Advanced Generic Corporation 2012-07-01
52083-0239-01 30 mL in 1 BOTTLE (52083-239-01) TUSICOF Kramer Novis 2010-08-17
52083-0239-04 120 mL in 1 BOTTLE (52083-239-04) TUSICOF Kramer Novis 2010-08-17
52083-0239-16 474 mL in 1 BOTTLE (52083-239-16) TUSICOF Kramer Novis 2012-10-08
52083-0639-16 474 mL in 1 BOTTLE (52083-639-16) G-TUSICOF Kramer Novis 2019-11-13
54859-0517-16 473 mL in 1 BOTTLE (54859-517-16) Tusnel DM Llorens Pharmaceutical International Division, Inc. 2019-05-01
63102-0104-16 474 mL in 1 BOTTLE, PLASTIC (63102-104-16) ACTINEL DM ACTIPHARMA, LLC 2019-05-20
Observed labelers: Kramer Novis (4) · ACTIPHARMA, LLC (1) · Advanced Generic Corporation (1) · Llorens Pharmaceutical International Division, Inc. (1) — this is the FDA-listed mapping footprint, not sales, inventory, availability, or market share.

🗃️ Sources & Limits

Atlas generation902fddb9-e9c1-4004-bf4c-dba4d51037c7
openFDA export observedJul 14, 2026
RxNorm release07/06/2026
Methodology2026-07-full-catalog-v1
  • A shared RxCUI does not prove interchangeability. Products mapped to the same concept are not thereby equivalent or substitutable — equivalence is a separate, product-level determination.
  • Listing here does not establish approval or coverage. Appearing in this snapshot is a data observation, not an FDA approval status or a payer coverage decision.
  • Missing data never means zero. A silent dataset (no price, no billing code, no utilization) means no observation — not that the real-world value is zero.
  • Counts describe the mapping footprint. Product, package, and labeler counts are the FDA-listed mapping footprint in this snapshot — not sales, inventory, availability, or market share.
This product uses publicly available data from the U.S. National Library of Medicine (NLM), National Institutes of Health, Department of Health and Human Services; NLM is not responsible for the product and does not endorse or recommend this or any other product.

Machine-readable JSON

Reference information about drug-concept identifiers and public regulatory data — not medical advice. Talk to your pharmacist or prescriber about your own medication.