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Histamine dihydrochloride 0.25 MG/ML Topical Cream — RxCUI 1091387

RxNorm drug concept · Semantic clinical drug
RxCUI 1091387 Semantic clinical drug · SCD ● Current RxNorm concept 4 FDA products 6 package NDCs Snapshot Jul 14, 2026

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Compiled from public NLM RxNorm and FDA (openFDA NDC directory) data sources. Editorial policy

What you’re looking at: the standardized identity of one medicine, as the U.S. drug-data system sees it. Below — every FDA-listed product, package code, price benchmark, and billing code that maps to it.

🗂️ Key Facts

RxCUI1091387
Official nameHistamine dihydrochloride 0.25 MG/ML Topical Cream
Concept typeSemantic clinical drug (SCD)
RxNorm statusCurrent RxNorm concept
Also known ashistamine dihydrochloride 0.025 % Topical Cream
FDA products mapped4
Package NDCs mapped6
RxNorm release07/06/2026
Snapshot dataJul 14, 2026

🕸️ Concept Web — How Histamine dihydrochloride 0.25 MG/ML Topical Cre... Connects

One RxCUI never lives alone. Follow the path from the raw ingredient down to the exact strength-and-form concepts FDA products carry — every stop is a real RxNorm concept with its own identifier. Hover or focus any chip for what it means.
This page's concept Histamine dihydrochloride 0.25 MG/ML Topical Cream RxCUI 1091387

Every web starts here: one RxCUI, one fixed meaning in the RxNorm vocabulary.

  1. Ingredients 2

    The active substance itself — no strength, form, or brand attached yet.

    • Histamine 5333
    • Histamine dihydrochloride 142136
  2. Dose forms 6

    The ingredient poured into a form — tablet, solution, cream — still without one fixed strength.

    • Histamine Topical Cream 1091386
    • Histamine dihydrochloride Topical Cream 2645947
    • Histamine Topical Product 1160920
    • Histamine dihydrochloride Topical Product 2663048
    • Topical Cream 316982
    • Topical Product 1151122
  3. Clinical & branded drugs 1

    Ingredient + strength + dose form. These are the concepts real FDA products actually carry.

    • Histamine dihydrochloride 0.25 MG/ML 1091385

Showing up to 8 concepts per family — 9 of 9 stored related concepts drawn.
These are official RxNorm vocabulary relationships — how concepts name and organize the same medicine. They do not establish therapeutic equivalence or substitutability: two concepts appearing in one web is never a statement that products can be swapped.

🔀 Generic ⇄ Brand Crosswalk

The same medicine has an unbranded (generic) identity and one or more brand-name identities — each with its own RxCUI. This is a naming relationship in RxNorm, not a statement that any two products are substitutable.

Generic (Clinical) Concepts

  • Histamine dihydrochloride 0.25 MG/ML SCDC · 1091385
  • Histamine Topical Cream SCDF · 1091386
  • Histamine dihydrochloride Topical Cream SCDFP · 2645947
  • Histamine Topical Product SCDG · 1160920
  • Histamine dihydrochloride Topical Product SCDGP · 2663048

📦 FDA Products & Package NDCs

4 products · 6 package NDCs
6 package NDCs map to RxCUI 1091387 in the current snapshot — up to 50 per page. Each linked NDC opens its full package page.
Package NDC Package Brand / generic name Labeler Marketing start
00363-5301-40 113 g in 1 JAR (0363-5301-40) Walgreens Arthritis Pain Relief Cream Walgreens Company 2022-04-30
61577-8120-01 1 JAR in 1 CARTON (61577-8120-1) / 59 g in 1 JAR (61577-812... Arthritis Pain Relief Cream Sombra Cosmetics Inc. 2024-10-23
61577-8120-05 1 JAR in 1 CARTON (61577-8120-5) / 119 g in 1 JAR (61577-81... Arthritis Pain Relief Cream Sombra Cosmetics Inc. 2024-10-23
61577-8120-08 1 JAR in 1 CARTON (61577-8120-8) / 266 g in 1 JAR (61577-81... Arthritis Pain Relief Cream Sombra Cosmetics Inc. 2024-10-23
69842-0301-60 1 JAR in 1 CARTON (69842-301-60) / 113 g in 1 JAR CVS Arthritis Pain Relief CVS Health 2016-05-30
82908-0357-00 81.33 mL in 1 JAR (82908-357-00) AMINO ACTIVE Topical Analgesic Cream VIREO SYSTEMS, INC. 2022-08-08
Observed labelers: Sombra Cosmetics Inc. (3) · CVS Health (1) · VIREO SYSTEMS, INC. (1) · Walgreens Company (1) — this is the FDA-listed mapping footprint, not sales, inventory, availability, or market share.

🗃️ Sources & Limits

Atlas generation902fddb9-e9c1-4004-bf4c-dba4d51037c7
openFDA export observedJul 14, 2026
RxNorm release07/06/2026
Methodology2026-07-full-catalog-v1
  • A shared RxCUI does not prove interchangeability. Products mapped to the same concept are not thereby equivalent or substitutable — equivalence is a separate, product-level determination.
  • Listing here does not establish approval or coverage. Appearing in this snapshot is a data observation, not an FDA approval status or a payer coverage decision.
  • Missing data never means zero. A silent dataset (no price, no billing code, no utilization) means no observation — not that the real-world value is zero.
  • Counts describe the mapping footprint. Product, package, and labeler counts are the FDA-listed mapping footprint in this snapshot — not sales, inventory, availability, or market share.
This product uses publicly available data from the U.S. National Library of Medicine (NLM), National Institutes of Health, Department of Health and Human Services; NLM is not responsible for the product and does not endorse or recommend this or any other product.

Machine-readable JSON

Reference information about drug-concept identifiers and public regulatory data — not medical advice. Talk to your pharmacist or prescriber about your own medication.