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Acetaminophen 325 MG / dextromethorphan hydrobromide 15 MG / doxylamine succinate 6.25 MG... — RxCUI 1094549

RxNorm drug concept · Semantic clinical drug
RxCUI 1094549 Semantic clinical drug · SCD ● Current RxNorm concept 130 FDA products 161 package NDCs Snapshot Jul 14, 2026

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Compiled from public NLM RxNorm and FDA (openFDA NDC directory) data sources. Editorial policy

What you’re looking at: the standardized identity of one medicine, as the U.S. drug-data system sees it. Below — every FDA-listed product, package code, price benchmark, and billing code that maps to it.

🗂️ Key Facts

RxCUI1094549
Official nameAcetaminophen 325 MG / dextromethorphan hydrobromide 15 MG / doxylamine succinate 6.25 MG Oral Capsule
Concept typeSemantic clinical drug (SCD)
RxNorm statusCurrent RxNorm concept
Also known asAPAP 325 MG / dextromethorphan hydrobromide 15 MG / doxylamine succinate 6.25 MG Oral Capsule; acetaminophen 325 MG / dextromethorphan HBr 15 MG / doxylamine succinate 6.25 MG Oral Capsule
FDA products mapped130
Package NDCs mapped161
RxNorm release07/06/2026
Snapshot dataJul 14, 2026

📖 Skip the Codes — Read It in Plain English.

Our pharmacist-built guide to Acetaminophen Injection: what it is, how it’s used, side effects, and interactions.

📗 Our plain-language guide HelloPharmacist
  • It treats mild to moderate pain, and moderate to severe pain when used with opioid medicines. It also lowers fever. It is given through a vein in a healthcare setting.
  • What is Acetaminophen Injection used for?
  • It is given as an IV infusion over 15 minutes by a healthcare professional. Your dose depends on your age and weight. Your care team follows the label and your prescriber's orders.
  • The most common are nausea and vomiting. Adults may also get headache or trouble sleeping. Children may have constipation or itching.
📖 Read our full Acetaminophen Injection guide →

🕸️ Concept Web — How Acetaminophen 325 MG / dextromethorphan hydrobro... Connects

One RxCUI never lives alone. Follow the path from the raw ingredient down to the exact strength-and-form concepts FDA products carry — every stop is a real RxNorm concept with its own identifier. Hover or focus any chip for what it means.
This page's concept Acetaminophen 325 MG / dextromethorphan hydrobromide 15 MG / doxylamine succinate 6.25 MG Oral Capsule RxCUI 1094549

Every web starts here: one RxCUI, one fixed meaning in the RxNorm vocabulary.

  1. Ingredients 6

    The active substance itself — no strength, form, or brand attached yet.

    • Acetaminophen 161
    • Dextromethorphan 3289
    • Doxylamine 3642
    • Acetaminophen / dextromethorphan / doxylamine 705258
    • Dextromethorphan hydrobromide 102490
    • Doxylamine succinate 23665
  2. Dose forms 9

    The ingredient poured into a form — tablet, solution, cream — still without one fixed strength.

    • Acetaminophen / dextromethorphan / doxylamine Oral Capsule 602750
    • Acetaminophen / dextromethorphan hydrobromide / doxylamine succinate Oral Capsule 2646221
    • Acetaminophen / dextromethorphan / doxylamine Oral Product 1155902
    • Acetaminophen / dextromethorphan / doxylamine Pill 1155903
    • Acetaminophen / dextromethorphan hydrobromide / doxylamine succinate Oral Product 2662124
    • Acetaminophen / dextromethorphan hydrobromide / doxylamine succinate Pill 2661483
    • Oral Capsule 316965
    • Oral Product 1151131
    • +1 more in this family
  3. Clinical & branded drugs 3

    Ingredient + strength + dose form. These are the concepts real FDA products actually carry.

    • Acetaminophen 325 MG 315263
    • Dextromethorphan hydrobromide 15 MG 1089821
    • Doxylamine succinate 6.25 MG 1052646
  4. Packs 2

    Fixed collections of drugs packaged and sold together, like dose packs.

Showing up to 8 concepts per family — 19 of 20 stored related concepts drawn.
These are official RxNorm vocabulary relationships — how concepts name and organize the same medicine. They do not establish therapeutic equivalence or substitutability: two concepts appearing in one web is never a statement that products can be swapped.

🔀 Generic ⇄ Brand Crosswalk

The same medicine has an unbranded (generic) identity and one or more brand-name identities — each with its own RxCUI. This is a naming relationship in RxNorm, not a statement that any two products are substitutable.

Generic (Clinical) Concepts

📦 FDA Products & Package NDCs

130 products · 161 package NDCs
161 package NDCs map to RxCUI 1094549 in the current snapshot — up to 50 per page. Each linked NDC opens its full package page.
Package NDC Package Brand / generic name Labeler Marketing start
00031-8744-10 5 BLISTER PACK in 1 CARTON (0031-8744-10) / 2 CAPSULE, LIQU... Robitussin Maximum Strength Severe Multi-Symptom 7 in 1 Relief Nighttime Haleon US Holdings LLC 2018-07-01
00113-0056-62 12 BLISTER PACK in 1 CARTON (0113-0056-62) / 2 CAPSULE, LIQ... good sense night time L. Perrigo Company 2014-08-25
00113-0056-67 24 BLISTER PACK in 1 CARTON (0113-0056-67) / 2 CAPSULE, LIQ... good sense night time L. Perrigo Company 2026-01-08
00113-0056-73 8 BLISTER PACK in 1 CARTON (0113-0056-73) / 2 CAPSULE, LIQU... good sense night time L. Perrigo Company 2014-05-30
00363-0729-24 2 BLISTER PACK in 1 CARTON (0363-0729-24) / 1 KIT in 1 BLIS... Daytime Nighttime Cold and Flu WALGREENS 2021-10-15
00363-0850-07 1 BLISTER PACK in 1 CARTON (0363-0850-07) / 10 CAPSULE, LIQ... Nighttime Cold and Flu WALGREENS 2023-09-19
00363-0850-24 2 BLISTER PACK in 1 CARTON (0363-0850-24) / 12 CAPSULE, LIQ... Nighttime Cold and Flu WALGREENS 2021-10-15
00363-8999-24 2 BLISTER PACK in 1 CARTON (0363-8999-24) / 12 CAPSULE, LIQ... Walgreens NightTime Cold and Flu WALGREEN COMPANY 2021-08-23
00363-9011-24 1 KIT in 1 PACKAGE, COMBINATION (0363-9011-24) * 8 CAPSULE... Cold and Flu Daytime, Nighttime, Multi-Symptom Walgreens 2021-08-24
00363-9012-48 1 KIT in 1 PACKAGE, COMBINATION (0363-9012-48) * 8 CAPSULE... Cold and Flu Daytime, Nighttime, Multi-Symptom Walgreens 2021-08-24
00904-6996-44 16 BLISTER PACK in 1 CARTON (0904-6996-44) / 1 CAPSULE, LIQ... Night Time Cold and Flu Relief Major Pharmaceuticals 2019-09-30
11673-0969-48 1 KIT in 1 BLISTER PACK (11673-969-48) * 24 CAPSULE, LIQUI... DAYTIME- NIGHTTIME COLD AND FLU TARGET CORP 2020-07-08
11673-0976-24 2 BLISTER PACK in 1 CARTON (11673-976-24) / 12 CAPSULE, LIQ... NIGHTIME COLD AND FLU TARGET CORP 2020-07-08
11822-0851-04 1 KIT in 1 KIT (11822-0851-4) * 16 BLISTER PACK in 1 CARTO... Daytime Nighttime Cold Flu Relief Rite Aid Corporation 2019-08-30
11822-1987-00 2 BLISTER PACK in 1 CARTON (11822-1987-0) / 12 CAPSULE, LIQ... MULTI-SYMPTOM COLD AND FLU RELIEF NIGHTTIME RITE AID 2021-09-15
11822-1987-09 4 BLISTER PACK in 1 CARTON (11822-1987-9) / 12 CAPSULE, LIQ... MULTI-SYMPTOM COLD AND FLU RELIEF NIGHTTIME RITE AID 2021-09-15
11822-3335-05 24 BLISTER PACK in 1 CARTON (11822-3335-5) / 1 CAPSULE, LIQ... Night Time Cold and Flu Relief Multi Symptom Rite Aid Corporation 2020-05-29
11822-3392-00 48 BLISTER PACK in 1 CARTON (11822-3392-0) / 1 CAPSULE, LIQ... Night Time Cold and Flu Relief Multi Symptom Rite Aid Corporation 2020-05-29
21130-0058-48 1 KIT in 1 KIT (21130-058-48) * 16 BLISTER PACK in 1 CARTO... Daytime Nighttime Cold Flu Relief Safeway, Inc. 2019-06-30
21130-0695-48 4 BLISTER PACK in 1 CARTON (21130-695-48) / 1 KIT in 1 BLIS... Daytime Cold and Flu and Nigttime Cold and Flu BETTER LIVING BRANDS LLC. 2023-07-14
21130-0849-24 24 BLISTER PACK in 1 CARTON (21130-849-24) / 1 CAPSULE, LIQ... Cold and Flu Relief Nighttime Safeway, Inc. 2019-06-30
21130-0899-24 24 BLISTER PACK in 1 CARTON (21130-899-24) / 1 CAPSULE, LIQ... Nighttime Cold and Flu Relief Safeway, Inc. 2019-11-29
21130-0901-48 1 KIT in 1 KIT (21130-901-48) * 16 BLISTER PACK in 1 CARTO... Daytime Nighttime Cold Flu Relief Safeway, Inc. 2019-12-27
21130-0940-24 2 BLISTER PACK in 1 CARTON (21130-940-24) / 12 CAPSULE, LIQ... Nighttime cold and flu relief BETTER LIVING BRANDS LLC. 2023-07-10
30142-0086-48 4 BLISTER PACK in 1 CARTON (30142-086-48) / 12 CAPSULE, LIQ... Kroger Nighttime Cold and Flu Softgel The Kroger Company 2022-08-31
30142-0233-74 1 KIT in 1 KIT (30142-233-74) * 8 CAPSULE, LIQUID FILLED i... Kroger Daytime and Nighttime Cold and Flu Softgel The Kroger Company 2022-08-31
35916-0154-01 1 BLISTER PACK in 1 CARTON (35916-0154-1) / 12 CAPSULE, LIQ... Acetaminophen, Dextromethorphan Hydrobromide and Doxylamine Succinate Softgel Healthcare Private Limited 2024-09-27
36800-0143-62 12 BLISTER PACK in 1 CARTON (36800-143-62) / 2 CAPSULE, LIQ... topcare nite time cold and flu Topco Associates LLC 2014-02-02
36800-0580-72 1 KIT in 1 CARTON (36800-580-72) * 8 BLISTER PACK in 1 CAR... Topcare Nite Time Day Time Cold and Flu Topco Associates LLC 2014-04-29
37808-0056-62 12 BLISTER PACK in 1 CARTON (37808-056-62) / 2 CAPSULE, LIQ... night time H E B 2014-04-14
37808-0095-16 1 BLISTER PACK in 1 CARTON (37808-095-16) / 8 CAPSULE, LIQU... Nightime H-E-B 2022-06-20
37808-0191-48 4 BLISTER PACK in 1 CARTON (37808-191-48) / 1 KIT in 1 BLIS... Daytime Nighttime H-E-B 2022-06-20
37835-0522-24 24 CAPSULE, LIQUID FILLED in 1 BOTTLE (37835-522-24) Nighttime Cold and Flu Relief Bi-Mart 2025-03-01
37835-0522-96 96 CAPSULE, LIQUID FILLED in 1 BOTTLE (37835-522-96) Nighttime Cold and Flu Relief Bi-Mart 2025-03-01
41163-0849-24 24 BLISTER PACK in 1 CARTON (41163-849-24) / 1 CAPSULE, LIQ... Nighttime Cold and Flu Relief Multi Symptom United Natural Foods, Inc. dba UNFI 2019-09-30
41163-0850-48 1 KIT in 1 KIT (41163-850-48) * 32 BLISTER PACK in 1 CARTO... Daytime Nighttime Cold Flu Relief United Natural Foods, Inc. dba UNFI 2019-09-30
41163-0899-24 24 BLISTER PACK in 1 CARTON (41163-899-24) / 1 CAPSULE, LIQ... Nighttime Cold and Flu Relief United Natural Foods, Inc. dba UNFI 2021-07-30
41163-0901-48 1 KIT in 1 KIT (41163-901-48) * 16 BLISTER PACK in 1 CARTO... Daytime Nighttime Cold Flu Relief United Natural Foods, Inc. dba UNFI 2021-07-30
41226-0694-24 2 BLISTER PACK in 1 CARTON (41226-694-24) / 12 CAPSULE, LIQ... NIGHTTIME COLD AND FLU Kroger Company 2021-05-11
42507-0056-62 12 BLISTER PACK in 1 CARTON (42507-056-62) / 2 CAPSULE, LIQ... Cold and Flu HyVee Inc 2014-03-24
46122-0245-62 12 BLISTER PACK in 1 CARTON (46122-245-62) / 2 CAPSULE, LIQ... Good Neighbor Pharmacy Night Time Amerisource Bergen 2014-03-06
49035-0192-48 1 KIT in 1 KIT (49035-192-48) * 16 BLISTER PACK in 1 CARTO... Daytime Nighttime Cold Flu Relief EQUATE (Wal-Mart Stores, Inc.) (see also WAL-MART INC) 2020-01-30
49035-0978-04 2 BLISTER PACK in 1 PACKAGE (49035-978-04) / 12 CAPSULE, LI... NiteTime Cold/Flu, Multi-Symptom Relief Wal-Mart Stores Inc 2016-03-09
49483-0695-48 4 BLISTER PACK in 1 CARTON (49483-695-48) / 1 KIT in 1 BLIS... Daytime Nighttime Cold and Flu TIME CAP LABORATORIES INC. 2023-06-07
50580-0131-24 2 BLISTER PACK in 1 CARTON (50580-131-24) / 12 CAPSULE, LIQ... TYLENOL COLD PLUS FLU MULTI-SYMPTOM GELS NIGHT Kenvue Brands LLC 2024-09-25
50580-0132-24 1 KIT in 1 PACKAGE (50580-132-24) * 2 BLISTER PACK in 1 KI... TYLENOL COLD PLUS FLU MULTI-SYMPTOM GELS DAY PLUS NIGHT Kenvue Brands LLC 2024-09-25
50580-0141-03 3 KIT in 1 PACKAGE (50580-141-03) / 1 KIT in 1 KIT * 2 BLI... TYLENOL Cold Plus Flu Multi-Symptom Liquid Gels Day Plus Night Kenvue Brands LLC 2025-06-30
53345-0006-01 1 BAG in 1 BOX (53345-006-01) / 4000 CAPSULE, LIQUID FILLED... Nighttime Cold and Flu Humanwell PuraCap Pharmaceutical (Wuhan), Ltd. 2013-04-15
53345-0026-01 1 BAG in 1 BOX (53345-026-01) / 4000 CAPSULE, LIQUID FILLED... Nighttime Cold and Flu Humanwell PuraCap Pharmaceutical (Wuhan), Ltd. 2014-08-11
53943-0603-03 2 BLISTER PACK in 1 CARTON (53943-603-03) / 12 CAPSULE, LIQ... Night Time Multi-Symptom Cold and Flu Relief Discount Drug Mart 2023-11-08
Observed labelers: CVS Pharmacy (10) · The Procter & Gamble Manufacturing Company (10) · VIVUNT PHARMA LLC (6) · OPMX LLC (5) · Walgreens (5) · Allegiant Health (4) · +61 more — this is the FDA-listed mapping footprint, not sales, inventory, availability, or market share.

🗃️ Sources & Limits

Atlas generation902fddb9-e9c1-4004-bf4c-dba4d51037c7
openFDA export observedJul 14, 2026
RxNorm release07/06/2026
Methodology2026-07-full-catalog-v1
  • A shared RxCUI does not prove interchangeability. Products mapped to the same concept are not thereby equivalent or substitutable — equivalence is a separate, product-level determination.
  • Listing here does not establish approval or coverage. Appearing in this snapshot is a data observation, not an FDA approval status or a payer coverage decision.
  • Missing data never means zero. A silent dataset (no price, no billing code, no utilization) means no observation — not that the real-world value is zero.
  • Counts describe the mapping footprint. Product, package, and labeler counts are the FDA-listed mapping footprint in this snapshot — not sales, inventory, availability, or market share.
This product uses publicly available data from the U.S. National Library of Medicine (NLM), National Institutes of Health, Department of Health and Human Services; NLM is not responsible for the product and does not endorse or recommend this or any other product.

Machine-readable JSON

Reference information about drug-concept identifiers and public regulatory data — not medical advice. Talk to your pharmacist or prescriber about your own medication.