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Ivacaftor 150 MG Oral Tablet [Kalydeco] — RxCUI 1243052

Name: Ivacaftor 150 MG Oral Tablet [Kalydeco] (RxCUI 1243052)
Creator: Brian Staiger, PharmD

RxNorm drug concept · Semantic branded drug

RxCUI 1243052 Semantic branded drug · SBD ● Current RxNorm concept 6 FDA products 7 package NDCs Snapshot Jul 14, 2026

This page is curated, coded, and maintained by Dr. Brian Staiger, PharmD

Compiled from public NLM RxNorm and FDA (openFDA NDC directory) data sources. Editorial policy

What you’re looking at: the standardized identity of one medicine, as the U.S. drug-data system sees it. Below — every FDA-listed product, package code, price benchmark, and billing code that maps to it.

🗂️ Key Facts

RxCUI1243052

Official nameIvacaftor 150 MG Oral Tablet [Kalydeco]

Concept typeSemantic branded drug (SBD)

RxNorm statusCurrent RxNorm concept

Also known asKalydeco 150 MG Oral Tablet

FDA products mapped6

Package NDCs mapped7

Reported Medicaid activity (SDUD)1,404 prescriptions · 14 state & territory Medicaid programs · latest period Q4 2025

RxNorm release07/06/2026

Snapshot dataJul 14, 2026

📖 Skip the Codes — Read It in Plain English.

Our pharmacist-built guide to Ivacaftor: what it is, how it’s used, side effects, and interactions.

📗 Our plain-language guide HelloPharmacist

Kalydeco doesn't cure cystic fibrosis, but it targets the root cause in people with certain gene mutations. It helps a faulty protein in your cells — called CFTR — work better by k...
What exactly does Kalydeco do for cystic fibrosis — does it cure it?
It really does matter what you take it with. Fat in food increases how much ivacaftor your body absorbs — by as much as 2.5 to 4 times. Taking it with just water means you're likel...
Why does it have to be taken with food? Can I just take it with water?

📖 Read our full Ivacaftor guide →

🕸️ Concept Web — How Ivacaftor 150 MG Oral Tablet [Kalydeco] Connects

One RxCUI never lives alone. Follow the path from the raw ingredient down to the exact strength-and-form concepts FDA products carry — every stop is a real RxNorm concept with its own identifier. Hover or focus any chip for what it means.

This page's concept Ivacaftor 150 MG Oral Tablet [Kalydeco] RxCUI 1243052 Semantic branded drug · SBD

Every web starts here: one RxCUI, one fixed meaning in the RxNorm vocabulary.

Ingredients 1

The active substance itself — no strength, form, or brand attached yet.
- Ivacaftor 1243041 IN
Brand names 1

The same medicine's trade names. A brand name alone says nothing about strength or form.
- Kalydeco 1243047 BN
Dose forms 9

The ingredient poured into a form — tablet, solution, cream — still without one fixed strength.
- Ivacaftor Oral Tablet 1243045 SCDF
- Ivacaftor Oral Product 1243043 SCDG
- Ivacaftor Pill 1243044 SCDG
- Ivacaftor Oral Tablet [Kalydeco] 1243049 SBDF
- Kalydeco Oral Product 1243050 SBDG
- Kalydeco Pill 1243051 SBDG
- Oral Tablet 317541 DF
- Oral Product 1151131 DFG
- +1 more in this family
Clinical & branded drugs 3

Ingredient + strength + dose form. These are the concepts real FDA products actually carry.
- Ivacaftor 150 MG Oral Tablet 1243046 SCD
- Ivacaftor 150 MG 1243042 SCDC
- Ivacaftor 150 MG [Kalydeco] 1243048 SBDC
Packs 2

Fixed collections of drugs packaged and sold together, like dose packs.
- {28 (ivacaftor 150 MG / tezacaftor 100 MG Oral Tablet) / 28 (ivacaftor 150 MG Oral Tablet) } Pack 1999388 GPCK
- {56 (elexacaftor 100 MG / ivacaftor 75 MG / tezacaftor 50 MG Oral Tablet) / 28 (ivacaftor 150 MG Oral Tablet) } Pack 2257012 GPCK

Showing up to 8 concepts per family — 15 of 16 stored related concepts drawn.

These are official RxNorm vocabulary relationships — how concepts name and organize the same medicine. They do not establish therapeutic equivalence or substitutability: two concepts appearing in one web is never a statement that products can be swapped.

🔀 Generic ⇄ Brand Crosswalk

The same medicine has an unbranded (generic) identity and one or more brand-name identities — each with its own RxCUI. This is a naming relationship in RxNorm, not a statement that any two products are substitutable.

Generic (Clinical) Concepts

Ivacaftor 150 MG Oral Tablet SCD · 1243046
{28 (ivacaftor 150 MG / tezacaftor 100 MG Oral Tablet) / 28 (ivacaftor 150 MG Oral Tablet) } Pack GPCK · 1999388
{56 (elexacaftor 100 MG / ivacaftor 75 MG / tezacaftor 50 MG Oral Tablet) / 28 (ivacaftor 150 MG Oral Tablet) } Pack GPCK · 2257012
Ivacaftor 150 MG SCDC · 1243042
Ivacaftor Oral Tablet SCDF · 1243045
Ivacaftor Oral Product SCDG · 1243043
Ivacaftor Pill SCDG · 1243044

Brand-Name Concepts

Ivacaftor 150 MG [Kalydeco] SBDC · 1243048
Ivacaftor Oral Tablet [Kalydeco] SBDF · 1243049
Kalydeco Oral Product SBDG · 1243050
Kalydeco Pill SBDG · 1243051
Kalydeco BN · 1243047

📦 FDA Products & Package NDCs

6 products · 7 package NDCs

7 package NDCs map to RxCUI 1243052 in the current snapshot — up to 50 per page. Each linked NDC opens its full package page.

Package NDC	Package	Brand / generic name	Labeler	Marketing start
51167-0200-01	4 BLISTER PACK in 1 CARTON (51167-200-01) / 14 TABLET, FILM...	Kalydeco	Vertex Pharmaceuticals Incorporated	2012-01-31
51167-0200-02	1 BOTTLE in 1 CARTON (51167-200-02) / 60 TABLET, FILM COATE...	Kalydeco	Vertex Pharmaceuticals Incorporated	2012-01-31
51167-0300-01	56 GRANULE in 1 CARTON (51167-300-01)	Kalydeco	Vertex Pharmaceuticals Incorporated	2015-03-23
51167-0400-01	56 GRANULE in 1 CARTON (51167-400-01)	Kalydeco	Vertex Pharmaceuticals Incorporated	2015-03-23
51167-0600-01	56 GRANULE in 1 CARTON (51167-600-01)	Kalydeco	Vertex Pharmaceuticals Incorporated	2019-04-29
51167-0770-01	56 GRANULE in 1 CARTON (51167-770-01)	Kalydeco	Vertex Pharmaceuticals Incorporated	2023-05-03
51167-0785-01	56 GRANULE in 1 CARTON (51167-785-01)	Kalydeco	Vertex Pharmaceuticals Incorporated	2023-05-03

Observed labelers: Vertex Pharmaceuticals Incorporated (7) — this is the FDA-listed mapping footprint, not sales, inventory, availability, or market share.

🗃️ Sources & Limits

Atlas generation902fddb9-e9c1-4004-bf4c-dba4d51037c7

openFDA export observedJul 14, 2026

RxNorm release07/06/2026

Methodology2026-07-full-catalog-v1

A shared RxCUI does not prove interchangeability. Products mapped to the same concept are not thereby equivalent or substitutable — equivalence is a separate, product-level determination.
Listing here does not establish approval or coverage. Appearing in this snapshot is a data observation, not an FDA approval status or a payer coverage decision.
Missing data never means zero. A silent dataset (no price, no billing code, no utilization) means no observation — not that the real-world value is zero.
Counts describe the mapping footprint. Product, package, and labeler counts are the FDA-listed mapping footprint in this snapshot — not sales, inventory, availability, or market share.

This product uses publicly available data from the U.S. National Library of Medicine (NLM), National Institutes of Health, Department of Health and Human Services; NLM is not responsible for the product and does not endorse or recommend this or any other product.

Machine-readable JSON

Reference information about drug-concept identifiers and public regulatory data — not medical advice. Talk to your pharmacist or prescriber about your own medication.