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Trametinib 0.5 MG Oral Tablet [Mekinist] — RxCUI 1425110

RxNorm drug concept · Semantic branded drug
RxCUI 1425110 Semantic branded drug · SBD ● Current RxNorm concept 3 FDA products 4 package NDCs Snapshot Jul 14, 2026

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Compiled from public NLM RxNorm and FDA (openFDA NDC directory) data sources. Editorial policy

What you’re looking at: the standardized identity of one medicine, as the U.S. drug-data system sees it. Below — every FDA-listed product, package code, price benchmark, and billing code that maps to it.

🗂️ Key Facts

RxCUI1425110
Official nameTrametinib 0.5 MG Oral Tablet [Mekinist]
Concept typeSemantic branded drug (SBD)
RxNorm statusCurrent RxNorm concept
Also known asMekinist 0.5 MG Oral Tablet; Mekinist 0.5 MG (as trametinib dimethyl sulfoxide 0.5635 MG) Oral Tablet
FDA products mapped3
Package NDCs mapped4
Reported Medicaid activity (SDUD)5,091 prescriptions · 30 state & territory Medicaid programs · latest period Q4 2025
RxNorm release07/06/2026
Snapshot dataJul 14, 2026

📖 Skip the Codes — Read It in Plain English.

Our pharmacist-built guide to Trametinib: what it is, how it’s used, side effects, and interactions.

📗 Our plain-language guide HelloPharmacist
  • Trametinib works by blocking a specific mutated protein called BRAF V600E or V600K. If your tumor doesn't carry that mutation, the drug has no target to act on — so it simply won't...
  • Why do I need a genetic test before starting this medicine?
  • Yes, it really does matter. If you're taking the Mekinist tablet, you need to take it on an empty stomach — at least an hour before eating or two hours after a meal. A high-fat mea...
  • Does it matter when I take it or whether I eat first?
📖 Read our full Trametinib guide →

🕸️ Concept Web — How Trametinib 0.5 MG Oral Tablet [Mekinist] Connects

One RxCUI never lives alone. Follow the path from the raw ingredient down to the exact strength-and-form concepts FDA products carry — every stop is a real RxNorm concept with its own identifier. Hover or focus any chip for what it means.
This page's concept Trametinib 0.5 MG Oral Tablet [Mekinist] RxCUI 1425110

Every web starts here: one RxCUI, one fixed meaning in the RxNorm vocabulary.

  1. Ingredients 1

    The active substance itself — no strength, form, or brand attached yet.

    • Trametinib 1425099
  2. Brand names 1

    The same medicine's trade names. A brand name alone says nothing about strength or form.

    • Mekinist 1425105
  3. Dose forms 9

    The ingredient poured into a form — tablet, solution, cream — still without one fixed strength.

    • Trametinib Oral Tablet 1425103
    • Trametinib Oral Product 1425101
    • Trametinib Pill 1425102
    • Trametinib Oral Tablet [Mekinist] 1425107
    • Mekinist Oral Product 1425108
    • Mekinist Pill 1425109
    • Oral Tablet 317541
    • Oral Product 1151131
    • +1 more in this family
  4. Clinical & branded drugs 3

    Ingredient + strength + dose form. These are the concepts real FDA products actually carry.

Showing up to 8 concepts per family — 13 of 14 stored related concepts drawn.
These are official RxNorm vocabulary relationships — how concepts name and organize the same medicine. They do not establish therapeutic equivalence or substitutability: two concepts appearing in one web is never a statement that products can be swapped.

🔀 Generic ⇄ Brand Crosswalk

The same medicine has an unbranded (generic) identity and one or more brand-name identities — each with its own RxCUI. This is a naming relationship in RxNorm, not a statement that any two products are substitutable.

Generic (Clinical) Concepts

  • Trametinib 0.5 MG Oral Tablet SCD · 1425104
  • Trametinib 0.5 MG SCDC · 1425100
  • Trametinib Oral Tablet SCDF · 1425103
  • Trametinib Oral Product SCDG · 1425101
  • Trametinib Pill SCDG · 1425102

Brand-Name Concepts

  • Trametinib 0.5 MG [Mekinist] SBDC · 1425106
  • Trametinib Oral Tablet [Mekinist] SBDF · 1425107
  • Mekinist Oral Product SBDG · 1425108
  • Mekinist Pill SBDG · 1425109
  • Mekinist BN · 1425105

📦 FDA Products & Package NDCs

3 products · 4 package NDCs
4 package NDCs map to RxCUI 1425110 in the current snapshot — up to 50 per page. Each linked NDC opens its full package page.
Package NDC Package Brand / generic name Labeler Marketing start
00078-1105-15 30 TABLET, FILM COATED in 1 BOTTLE (0078-1105-15) Mekinist Novartis Pharmaceuticals Corporation 2021-12-22
00078-1112-15 30 TABLET, FILM COATED in 1 BOTTLE (0078-1112-15) Mekinist Novartis Pharmaceuticals Corporation 2021-12-22
00078-1112-94 14 TABLET, FILM COATED in 1 BOTTLE (0078-1112-94) Mekinist Novartis Pharmaceuticals Corporation 2021-12-22
00078-1161-47 90 mL in 1 BOTTLE (0078-1161-47) Mekinist Novartis Pharmaceuticals Corporation 2023-03-16
Observed labelers: Novartis Pharmaceuticals Corporation (4) — this is the FDA-listed mapping footprint, not sales, inventory, availability, or market share.

🗃️ Sources & Limits

Atlas generation902fddb9-e9c1-4004-bf4c-dba4d51037c7
openFDA export observedJul 14, 2026
RxNorm release07/06/2026
Methodology2026-07-full-catalog-v1
  • A shared RxCUI does not prove interchangeability. Products mapped to the same concept are not thereby equivalent or substitutable — equivalence is a separate, product-level determination.
  • Listing here does not establish approval or coverage. Appearing in this snapshot is a data observation, not an FDA approval status or a payer coverage decision.
  • Missing data never means zero. A silent dataset (no price, no billing code, no utilization) means no observation — not that the real-world value is zero.
  • Counts describe the mapping footprint. Product, package, and labeler counts are the FDA-listed mapping footprint in this snapshot — not sales, inventory, availability, or market share.
This product uses publicly available data from the U.S. National Library of Medicine (NLM), National Institutes of Health, Department of Health and Human Services; NLM is not responsible for the product and does not endorse or recommend this or any other product.

Machine-readable JSON

Reference information about drug-concept identifiers and public regulatory data — not medical advice. Talk to your pharmacist or prescriber about your own medication.