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Dextromethorphan hydrobromide 20 MG / guaifenesin 380 MG / pseudoephedrine hydrochloride 6... — RxCUI 1427998

Name: Dextromethorphan hydrobromide 20 MG / guaifenesin 380 MG / pseudoephedrine hydrochlor… (RxCUI 1427998)
Creator: Brian Staiger, PharmD

RxNorm drug concept · Semantic clinical drug

RxCUI 1427998 Semantic clinical drug · SCD ● Current RxNorm concept 1 FDA product 2 package NDCs Snapshot Jul 14, 2026

This page is curated, coded, and maintained by Dr. Brian Staiger, PharmD

Compiled from public NLM RxNorm and FDA (openFDA NDC directory) data sources. Editorial policy

What you’re looking at: the standardized identity of one medicine, as the U.S. drug-data system sees it. Below — every FDA-listed product, package code, price benchmark, and billing code that maps to it.

🗂️ Key Facts

RxCUI1427998

Official nameDextromethorphan hydrobromide 20 MG / guaifenesin 380 MG / pseudoephedrine hydrochloride 60 MG Oral Tablet

Concept typeSemantic clinical drug (SCD)

RxNorm statusCurrent RxNorm concept

Also known asdextromethorphan HBr 20 MG / guaiFENesin 380 MG / pseudoephedrine HCl 60 MG Oral Tablet

FDA products mapped1

Package NDCs mapped2

Reported Medicaid activity (SDUD)1,330 prescriptions · 1 state & territory Medicaid programs · latest period Q4 2025

RxNorm release07/06/2026

Snapshot dataJul 14, 2026

📖 Skip the Codes — Read It in Plain English.

Our pharmacist-built guide to Dextromethorphan: what it is, how it’s used, side effects, and interactions.

📗 Our plain-language guide HelloPharmacist

It won't necessarily silence your cough entirely, but it does temporarily suppress the cough reflex and reduce how intense and frequent your cough is. It can also help reduce that...
What exactly does dextromethorphan do — will it stop my cough completely?
It depends on your child's age and the specific product. Most dextromethorphan products should not be given to children under 4 years old without a doctor's guidance. Some products...
This is a really important question. If your antidepressant is an MAOI (monoamine oxidase inhibitor), you absolutely cannot take dextromethorphan — not while you're on it, and not...

📖 Read our full Dextromethorphan guide →

🕸️ Concept Web — How Dextromethorphan hydrobromide 20 MG / guaifenesi... Connects

One RxCUI never lives alone. Follow the path from the raw ingredient down to the exact strength-and-form concepts FDA products carry — every stop is a real RxNorm concept with its own identifier. Hover or focus any chip for what it means.

This page's concept Dextromethorphan hydrobromide 20 MG / guaifenesin 380 MG / pseudoephedrine hydrochloride 60 MG Oral Tablet RxCUI 1427998 Semantic clinical drug · SCD

Every web starts here: one RxCUI, one fixed meaning in the RxNorm vocabulary.

Ingredients 6

The active substance itself — no strength, form, or brand attached yet.
- Dextromethorphan 3289 IN
- Guaifenesin 5032 IN
- Pseudoephedrine 8896 IN
- Dextromethorphan / guaifenesin / pseudoephedrine 214495 MIN
- Dextromethorphan hydrobromide 102490 PIN
- Pseudoephedrine hydrochloride 91168 PIN
Dose forms 9

The ingredient poured into a form — tablet, solution, cream — still without one fixed strength.
- Dextromethorphan / guaifenesin / pseudoephedrine Oral Tablet 374747 SCDF
- Dextromethorphan hydrobromide / guaifenesin / pseudoephedrine hydrochloride Oral Tablet 2645434 SCDFP
- Dextromethorphan / guaifenesin / pseudoephedrine Oral Product 1154866 SCDG
- Dextromethorphan / guaifenesin / pseudoephedrine Pill 1154867 SCDG
- Dextromethorphan hydrobromide / guaifenesin / pseudoephedrine hydrochloride Oral Product 2662344 SCDGP
- Dextromethorphan hydrobromide / guaifenesin / pseudoephedrine hydrochloride Pill 2662742 SCDGP
- Oral Tablet 317541 DF
- Oral Product 1151131 DFG
- +1 more in this family
Clinical & branded drugs 3

Ingredient + strength + dose form. These are the concepts real FDA products actually carry.
- Dextromethorphan hydrobromide 20 MG 1037200 SCDC
- Guaifenesin 380 MG 794642 SCDC
- Pseudoephedrine hydrochloride 60 MG 996721 SCDC

Showing up to 8 concepts per family — 17 of 18 stored related concepts drawn.

These are official RxNorm vocabulary relationships — how concepts name and organize the same medicine. They do not establish therapeutic equivalence or substitutability: two concepts appearing in one web is never a statement that products can be swapped.

🔀 Generic ⇄ Brand Crosswalk

The same medicine has an unbranded (generic) identity and one or more brand-name identities — each with its own RxCUI. This is a naming relationship in RxNorm, not a statement that any two products are substitutable.

Generic (Clinical) Concepts

Dextromethorphan hydrobromide 20 MG SCDC · 1037200
Guaifenesin 380 MG SCDC · 794642
Pseudoephedrine hydrochloride 60 MG SCDC · 996721
Dextromethorphan / guaifenesin / pseudoephedrine Oral Tablet SCDF · 374747
Dextromethorphan hydrobromide / guaifenesin / pseudoephedrine hydrochloride Oral Tablet SCDFP · 2645434
Dextromethorphan / guaifenesin / pseudoephedrine Oral Product SCDG · 1154866
Dextromethorphan / guaifenesin / pseudoephedrine Pill SCDG · 1154867
Dextromethorphan hydrobromide / guaifenesin / pseudoephedrine hydrochloride Oral Product SCDGP · 2662344
Dextromethorphan hydrobromide / guaifenesin / pseudoephedrine hydrochloride Pill SCDGP · 2662742

📦 FDA Products & Package NDCs

1 product · 2 package NDCs

2 package NDCs map to RxCUI 1427998 in the current snapshot — up to 50 per page. Each linked NDC opens its full package page.

Package NDC	Package	Brand / generic name	Labeler	Marketing start
50991-0214-01	100 TABLET in 1 BOTTLE (50991-214-01)	Poly-Vent DM	Poly Pharmaceuticals, Inc.	2013-06-17
50991-0214-02	12 POUCH in 1 CARTON (50991-214-02) / 1 TABLET in 1 POUCH	Poly-Vent DM	Poly Pharmaceuticals, Inc.	2013-06-17

Observed labelers: Poly Pharmaceuticals, Inc. (2) — this is the FDA-listed mapping footprint, not sales, inventory, availability, or market share.

💲 Pricing (NADAC)

NADAC is CMS's National Average Drug Acquisition Cost — roughly what pharmacies pay to buy the drug. It is an acquisition benchmark, not your copay.

Per ea · median

$0.6289

Range $0.6289–$0.6289 · middle 50% $0.6289–$0.6289 · 1 NDCs

Latest compatible distributions from the CMS NADAC file · dataset watermark 2026-07-10. Prices vary by package and pharmacy; a distribution is shown instead of one misleading number. Rows the dataset is silent on carry no price. No zero-cost conclusion should be drawn.

🗃️ Sources & Limits

Atlas generation902fddb9-e9c1-4004-bf4c-dba4d51037c7

openFDA export observedJul 14, 2026

RxNorm release07/06/2026

Methodology2026-07-full-catalog-v1

A shared RxCUI does not prove interchangeability. Products mapped to the same concept are not thereby equivalent or substitutable — equivalence is a separate, product-level determination.
Listing here does not establish approval or coverage. Appearing in this snapshot is a data observation, not an FDA approval status or a payer coverage decision.
Missing data never means zero. A silent dataset (no price, no billing code, no utilization) means no observation — not that the real-world value is zero.
Counts describe the mapping footprint. Product, package, and labeler counts are the FDA-listed mapping footprint in this snapshot — not sales, inventory, availability, or market share.

This product uses publicly available data from the U.S. National Library of Medicine (NLM), National Institutes of Health, Department of Health and Human Services; NLM is not responsible for the product and does not endorse or recommend this or any other product.

Machine-readable JSON

Reference information about drug-concept identifiers and public regulatory data — not medical advice. Talk to your pharmacist or prescriber about your own medication.