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Acetaminophen 300 MG / butalbital 50 MG / caffeine 40 MG / codeine phosphate 30 MG Oral Ca... — RxCUI 1431286

RxNorm drug concept · Semantic clinical drug
RxCUI 1431286 Semantic clinical drug · SCD ● Current RxNorm concept 4 FDA products 4 package NDCs Snapshot Jul 14, 2026

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Compiled from public NLM RxNorm and FDA (openFDA NDC directory) data sources. Editorial policy

What you’re looking at: the standardized identity of one medicine, as the U.S. drug-data system sees it. Below — every FDA-listed product, package code, price benchmark, and billing code that maps to it.

🗂️ Key Facts

RxCUI1431286
Official nameAcetaminophen 300 MG / butalbital 50 MG / caffeine 40 MG / codeine phosphate 30 MG Oral Capsule
Concept typeSemantic clinical drug (SCD)
RxNorm statusCurrent RxNorm concept
Also known asAPAP 300 MG / butalbital 50 MG / Caffeine 40 MG / Codeine Phosphate 30 MG Oral Capsule
FDA products mapped4
Package NDCs mapped4
Reported Medicaid activity (SDUD)2,590 prescriptions · 29 state & territory Medicaid programs · latest period Q4 2025
RxNorm release07/06/2026
Snapshot dataJul 14, 2026

📖 Skip the Codes — Read It in Plain English.

Our pharmacist-built guide to Acetaminophen Injection: what it is, how it’s used, side effects, and interactions.

📗 Our plain-language guide HelloPharmacist
  • Great question. The IV form is used when you can't take medication by mouth — for example, after surgery, if you're nauseated, or if you need faster, more reliable absorption. It d...
  • Why am I getting acetaminophen through an IV instead of just taking a pill?
  • Yes, Acetaminophen Injection is approved for children — for pain relief in kids 2 years and older, and for fever reduction in patients of all ages, including premature newborns bor...
  • The most important things to watch for are signs of a serious allergic reaction — swelling of your face, mouth, or throat, trouble breathing, or hives — and any new skin rash. Eith...
📖 Read our full Acetaminophen Injection guide →

🕸️ Concept Web — How Acetaminophen 300 MG / butalbital 50 MG / caffei... Connects

One RxCUI never lives alone. Follow the path from the raw ingredient down to the exact strength-and-form concepts FDA products carry — every stop is a real RxNorm concept with its own identifier. Hover or focus any chip for what it means.
This page's concept Acetaminophen 300 MG / butalbital 50 MG / caffeine 40 MG / codeine phosphate 30 MG Oral Capsule RxCUI 1431286

Every web starts here: one RxCUI, one fixed meaning in the RxNorm vocabulary.

  1. Ingredients 6

    The active substance itself — no strength, form, or brand attached yet.

    • Acetaminophen 161
    • Butalbital 19860
    • Caffeine 1886
    • Codeine 2670
    • Acetaminophen / butalbital / caffeine / codeine 689561
    • Codeine phosphate 2672
  2. Brand names 1

    The same medicine's trade names. A brand name alone says nothing about strength or form.

    • Fioricet with Codeine 217126
  3. Dose forms 13

    The ingredient poured into a form — tablet, solution, cream — still without one fixed strength.

    • Acetaminophen / butalbital / caffeine / codeine Oral Capsule 374830
    • Acetaminophen / butalbital / caffeine / codeine phosphate Oral Capsule 2648123
    • Acetaminophen / butalbital / caffeine / codeine Oral Product 1152250
    • Acetaminophen / butalbital / caffeine / codeine Pill 1152251
    • Acetaminophen / butalbital / caffeine / codeine phosphate Oral Product 2660619
    • Acetaminophen / butalbital / caffeine / codeine phosphate Pill 2661139
    • Acetaminophen / butalbital / caffeine / codeine Oral Capsule [Fioricet with Codeine] 366536
    • Acetaminophen / butalbital / caffeine / codeine phosphate Oral Capsule [Fioricet with Codeine] 2654895
    • +5 more in this family
  4. Clinical & branded drugs 6

    Ingredient + strength + dose form. These are the concepts real FDA products actually carry.

Showing up to 8 concepts per family — 21 of 26 stored related concepts drawn.
These are official RxNorm vocabulary relationships — how concepts name and organize the same medicine. They do not establish therapeutic equivalence or substitutability: two concepts appearing in one web is never a statement that products can be swapped.

🔀 Generic ⇄ Brand Crosswalk

The same medicine has an unbranded (generic) identity and one or more brand-name identities — each with its own RxCUI. This is a naming relationship in RxNorm, not a statement that any two products are substitutable.

Generic (Clinical) Concepts

  • Acetaminophen 300 MG SCDC · 315261
  • Butalbital 50 MG SCDC · 317309
  • Caffeine 40 MG SCDC · 317310
  • Codeine phosphate 30 MG SCDC · 993780
  • Acetaminophen / butalbital / caffeine / codeine Oral Capsule SCDF · 374830
  • Acetaminophen / butalbital / caffeine / codeine phosphate Oral Capsule SCDFP · 2648123
  • Acetaminophen / butalbital / caffeine / codeine Oral Product SCDG · 1152250
  • Acetaminophen / butalbital / caffeine / codeine Pill SCDG · 1152251
  • Acetaminophen / butalbital / caffeine / codeine phosphate Oral Product SCDGP · 2660619
  • Acetaminophen / butalbital / caffeine / codeine phosphate Pill SCDGP · 2661139

Brand-Name Concepts

  • Acetaminophen 300 MG / butalbital 50 MG / caffeine 40 MG / codeine phosphate 30 MG Oral Capsule [Fioricet with Codeine] SBD · 1433802
  • Acetaminophen 300 MG / butalbital 50 MG / caffeine 40 MG / codeine phosphate 30 MG [Fioricet with Codeine] SBDC · 1433801
  • Acetaminophen / butalbital / caffeine / codeine Oral Capsule [Fioricet with Codeine] SBDF · 366536
  • Acetaminophen / butalbital / caffeine / codeine phosphate Oral Capsule [Fioricet with Codeine] SBDFP · 2654895
  • Fioricet with Codeine Oral Product SBDG · 1168324
  • Fioricet with Codeine Pill SBDG · 1168325
  • Fioricet with Codeine BN · 217126

📦 FDA Products & Package NDCs

4 products · 4 package NDCs
4 package NDCs map to RxCUI 1431286 in the current snapshot — up to 50 per page. Each linked NDC opens its full package page.
Package NDC Package Brand / generic name Labeler Marketing start
00054-0650-25 100 CAPSULE in 1 BOTTLE (0054-0650-25) Butalbital, Acetaminophen, Caffeine and Codeine Phosphate Hikma Pharmaceuticals USA Inc. 2022-05-09
00054-3000-01 100 CAPSULE in 1 BOTTLE (0054-3000-01) Butalbital, Acetaminophen, Caffeine and Codeine Phosphate Hikma Pharmaceuticals USA Inc. 2022-05-09
00591-2641-01 100 CAPSULE in 1 BOTTLE, PLASTIC (0591-2641-01) Butalbital, Acetaminophen, Caffeine, and Codeine Phosphate Actavis Pharma, Inc. 2013-07-29
52544-0082-01 100 CAPSULE in 1 BOTTLE, PLASTIC (52544-082-01) Fioricet with Codeine Actavis Pharma, Inc. 2013-07-29
Observed labelers: Actavis Pharma, Inc. (2) · Hikma Pharmaceuticals USA Inc. (2) — this is the FDA-listed mapping footprint, not sales, inventory, availability, or market share.

🗃️ Sources & Limits

Atlas generation902fddb9-e9c1-4004-bf4c-dba4d51037c7
openFDA export observedJul 14, 2026
RxNorm release07/06/2026
Methodology2026-07-full-catalog-v1
  • A shared RxCUI does not prove interchangeability. Products mapped to the same concept are not thereby equivalent or substitutable — equivalence is a separate, product-level determination.
  • Listing here does not establish approval or coverage. Appearing in this snapshot is a data observation, not an FDA approval status or a payer coverage decision.
  • Missing data never means zero. A silent dataset (no price, no billing code, no utilization) means no observation — not that the real-world value is zero.
  • Counts describe the mapping footprint. Product, package, and labeler counts are the FDA-listed mapping footprint in this snapshot — not sales, inventory, availability, or market share.
This product uses publicly available data from the U.S. National Library of Medicine (NLM), National Institutes of Health, Department of Health and Human Services; NLM is not responsible for the product and does not endorse or recommend this or any other product.

Machine-readable JSON

Reference information about drug-concept identifiers and public regulatory data — not medical advice. Talk to your pharmacist or prescriber about your own medication.