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Acetaminophen 250 MG / dextromethorphan hydrobromide 10 MG / guaifenesin 200 MG / phenylep... — RxCUI 1432488

RxNorm drug concept · Semantic clinical drug
RxCUI 1432488 Semantic clinical drug · SCD ● Current RxNorm concept 3 FDA products 3 package NDCs Snapshot Jul 14, 2026

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Compiled from public NLM RxNorm and FDA (openFDA NDC directory) data sources. Editorial policy

What you’re looking at: the standardized identity of one medicine, as the U.S. drug-data system sees it. Below — every FDA-listed product, package code, price benchmark, and billing code that maps to it.

🗂️ Key Facts

RxCUI1432488
Official nameAcetaminophen 250 MG / dextromethorphan hydrobromide 10 MG / guaifenesin 200 MG / phenylephrine hydrochloride 5 MG Oral Capsule
Concept typeSemantic clinical drug (SCD)
RxNorm statusCurrent RxNorm concept
Also known asAPAP 250 MG / Dextromethorphan Hydrobromide 10 MG / Guaifenesin 200 MG / Phenylephrine Hydrochloride 5 MG Oral Capsule; acetaminophen 250 MG / dextromethorphan HBr 10 MG / guaiFENesin 200 MG / phenylephrine HCl 5 MG Oral Capsule
FDA products mapped3
Package NDCs mapped3
RxNorm release07/06/2026
Snapshot dataJul 14, 2026

📖 Skip the Codes — Read It in Plain English.

Our pharmacist-built guide to Phenylephrine: what it is, how it’s used, side effects, and interactions.

📗 Our plain-language guide HelloPharmacist
  • Yes, it's the same active ingredient, but used in very different ways depending on the form. The nasal spray delivers a tiny amount directly to the nasal lining to temporarily shri...
  • I see phenylephrine in nasal sprays at the pharmacy AND as an IV drug in the hospital — is it really the same medication?
  • You should check with your doctor first. Phenylephrine constricts blood vessels, which can raise blood pressure and put extra strain on the heart — even from a nasal spray. If you...
  • Can I use the nasal spray if I have high blood pressure or heart disease?
📖 Read our full Phenylephrine guide →

🕸️ Concept Web — How Acetaminophen 250 MG / dextromethorphan hydrobro... Connects

One RxCUI never lives alone. Follow the path from the raw ingredient down to the exact strength-and-form concepts FDA products carry — every stop is a real RxNorm concept with its own identifier. Hover or focus any chip for what it means.
This page's concept Acetaminophen 250 MG / dextromethorphan hydrobromide 10 MG / guaifenesin 200 MG / phenylephrine hydrochloride 5 MG Oral Capsule RxCUI 1432488

Every web starts here: one RxCUI, one fixed meaning in the RxNorm vocabulary.

  1. Ingredients 7

    The active substance itself — no strength, form, or brand attached yet.

    • Acetaminophen 161
    • Dextromethorphan 3289
    • Guaifenesin 5032
    • Phenylephrine 8163
    • Acetaminophen / dextromethorphan / guaifenesin / phenylephrine 689776
    • Dextromethorphan hydrobromide 102490
    • Phenylephrine hydrochloride 8164
  2. Dose forms 9

    The ingredient poured into a form — tablet, solution, cream — still without one fixed strength.

    • Acetaminophen / dextromethorphan / guaifenesin / phenylephrine Oral Capsule 1145621
    • Acetaminophen / dextromethorphan hydrobromide / guaifenesin / phenylephrine hydrochloride Oral Capsule 2648118
    • Acetaminophen / dextromethorphan / guaifenesin / phenylephrine Oral Product 1155905
    • Acetaminophen / dextromethorphan / guaifenesin / phenylephrine Pill 1155906
    • Acetaminophen / dextromethorphan hydrobromide / guaifenesin / phenylephrine hydrochloride Oral Product 2662312
    • Acetaminophen / dextromethorphan hydrobromide / guaifenesin / phenylephrine hydrochloride Pill 2659957
    • Oral Capsule 316965
    • Oral Product 1151131
    • +1 more in this family
  3. Clinical & branded drugs 4

    Ingredient + strength + dose form. These are the concepts real FDA products actually carry.

    • Acetaminophen 250 MG 315259
    • Dextromethorphan hydrobromide 10 MG 1014455
    • Guaifenesin 200 MG 317384
    • Phenylephrine hydrochloride 5 MG 1020198
  4. Packs 1

    Fixed collections of drugs packaged and sold together, like dose packs.

Showing up to 8 concepts per family — 20 of 21 stored related concepts drawn.
These are official RxNorm vocabulary relationships — how concepts name and organize the same medicine. They do not establish therapeutic equivalence or substitutability: two concepts appearing in one web is never a statement that products can be swapped.

🔀 Generic ⇄ Brand Crosswalk

The same medicine has an unbranded (generic) identity and one or more brand-name identities — each with its own RxCUI. This is a naming relationship in RxNorm, not a statement that any two products are substitutable.

Generic (Clinical) Concepts

📦 FDA Products & Package NDCs

3 products · 3 package NDCs
3 package NDCs map to RxCUI 1432488 in the current snapshot — up to 50 per page. Each linked NDC opens its full package page.
Package NDC Package Brand / generic name Labeler Marketing start
00280-0505-20 2 BLISTER PACK in 1 CARTON (0280-0505-20) / 20 CAPSULE, LIQ... Alka-Seltzer Plus Severe Cough Mucus and Congestion Liquid Gels Bayer HealthCare LLC. 2015-01-07
00280-0506-20 1 KIT in 1 CARTON (0280-0506-20) * 2 BLISTER PACK in 1 CAR... Alka-Seltzer Plus Severe Cough Mucus and Congestion Day and Night Bayer HealthCare LLC. 2017-05-30
00280-0507-20 2 BLISTER PACK in 1 CARTON (0280-0507-20) / 20 CAPSULE, LIQ... Alka-Seltzer Plus Severe Sinus Cold and Cough Liquid Gels Bayer HealthCare LLC. 2015-01-28
Observed labelers: Bayer HealthCare LLC. (3) — this is the FDA-listed mapping footprint, not sales, inventory, availability, or market share.

🗃️ Sources & Limits

Atlas generation902fddb9-e9c1-4004-bf4c-dba4d51037c7
openFDA export observedJul 14, 2026
RxNorm release07/06/2026
Methodology2026-07-full-catalog-v1
  • A shared RxCUI does not prove interchangeability. Products mapped to the same concept are not thereby equivalent or substitutable — equivalence is a separate, product-level determination.
  • Listing here does not establish approval or coverage. Appearing in this snapshot is a data observation, not an FDA approval status or a payer coverage decision.
  • Missing data never means zero. A silent dataset (no price, no billing code, no utilization) means no observation — not that the real-world value is zero.
  • Counts describe the mapping footprint. Product, package, and labeler counts are the FDA-listed mapping footprint in this snapshot — not sales, inventory, availability, or market share.
This product uses publicly available data from the U.S. National Library of Medicine (NLM), National Institutes of Health, Department of Health and Human Services; NLM is not responsible for the product and does not endorse or recommend this or any other product.

Machine-readable JSON

Reference information about drug-concept identifiers and public regulatory data — not medical advice. Talk to your pharmacist or prescriber about your own medication.