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Salicylic acid 20 MG/ML Topical Solution [Clear Proof Acne Medication] — RxCUI 1491648

Name: Salicylic acid 20 MG/ML Topical Solution [Clear Proof Acne Medication] (RxCUI 1491648)
Creator: Brian Staiger, PharmD

RxNorm drug concept · Semantic branded drug

RxCUI 1491648 Semantic branded drug · SBD ● Current RxNorm concept 3 FDA products 4 package NDCs Snapshot Jul 14, 2026

This page is curated, coded, and maintained by Dr. Brian Staiger, PharmD

Compiled from public NLM RxNorm and FDA (openFDA NDC directory) data sources. Editorial policy

What you’re looking at: the standardized identity of one medicine, as the U.S. drug-data system sees it. Below — every FDA-listed product, package code, price benchmark, and billing code that maps to it.

🗂️ Key Facts

RxCUI1491648

Official nameSalicylic acid 20 MG/ML Topical Solution [Clear Proof Acne Medication]

Concept typeSemantic branded drug (SBD)

RxNorm statusCurrent RxNorm concept

Also known asClear Proof Acne Medication 20 MG/ML Topical Solution; clearproof acne medication 2 % Topical Solution; Clear Proof Blemish Control Toner 2 % Topical Solution

FDA products mapped3

Package NDCs mapped4

RxNorm release07/06/2026

Snapshot dataJul 14, 2026

📖 Skip the Codes — Read It in Plain English.

Our pharmacist-built guide to Salicylic Acid Topical: what it is, how it’s used, side effects, and interactions.

📗 Our plain-language guide HelloPharmacist

It is used in a facial routine for acne-prone and oil-prone skin. The routine includes a cleanser, serum, toner and emulsion. Salicylic acid helps loosen and shed dead skin cells.
Use the cleanser morning and evening, and the serum in the morning after cleansing. Use the toner in the evening on dry skin, and the emulsion at night after cleansing. Avoid your...
Mild stinging, burning, itching, dryness and extra peeling can happen. If dryness or peeling bothers you, try using the serum or toner every other day. If it gets excessive, stop a...
It is best not to. Using another topical acne medication at the same time makes irritation and dryness more likely. If you get irritated, use only one at a time.

📖 Read our full Salicylic Acid Topical guide →

🕸️ Concept Web — How Salicylic acid 20 MG/ML Topical Solution [Clear... Connects

One RxCUI never lives alone. Follow the path from the raw ingredient down to the exact strength-and-form concepts FDA products carry — every stop is a real RxNorm concept with its own identifier. Hover or focus any chip for what it means.

This page's concept Salicylic acid 20 MG/ML Topical Solution [Clear Proof Acne Medication] RxCUI 1491648 Semantic branded drug · SBD

Every web starts here: one RxCUI, one fixed meaning in the RxNorm vocabulary.

Ingredients 1

The active substance itself — no strength, form, or brand attached yet.
- Salicylic acid 9525 IN
Brand names 1

The same medicine's trade names. A brand name alone says nothing about strength or form.
- Clear Proof Acne Medication 1491644 BN
Dose forms 6

The ingredient poured into a form — tablet, solution, cream — still without one fixed strength.
- Salicylic acid Topical Solution 238464 SCDF
- Salicylic acid Topical Product 1157604 SCDG
- Salicylic acid Topical Solution [Clear Proof Acne Medication] 1491646 SBDF
- Clear Proof Acne Medication Topical Product 1491647 SBDG
- Topical Solution 316986 DF
- Topical Product 1151122 DFG
Clinical & branded drugs 3

Ingredient + strength + dose form. These are the concepts real FDA products actually carry.
- Salicylic acid 20 MG/ML Topical Solution 251577 SCD
- Salicylic acid 20 MG/ML 328925 SCDC
- Salicylic acid 20 MG/ML [Clear Proof Acne Medication] 1491645 SBDC
Packs 6

Fixed collections of drugs packaged and sold together, like dose packs.
- {1 (28000 MG) (benzoyl peroxide 0.05 MG/MG Topical Gel [Clear Proof Acne Treatment]) / 1 (127000 MG) (salicylic acid 20 MG/ML Medicated Liquid Soap [Clear Proof Acne Medication]) / 1 (147 ML) (salicylic acid 20 MG/ML Topical Solution [Clear Proof Acne Medication]) } Pack [Clear Proof Acne System] 1493510 BPCK
- {1 (3000 MG) (benzoyl peroxide 0.05 MG/MG Topical Gel [Clear Proof Acne Treatment]) / 1 (28000 MG) (salicylic acid 20 MG/ML Medicated Liquid Soap [Clear Proof Acne Medication]) / 1 (26 ML) (salicylic acid 20 MG/ML Topical Solution [Clear Proof Acne Medication]) } Pack [Clear Proof Acne To-Go System] 1493512 BPCK
- {1 (240 ML) (benzoyl peroxide 25 MG/ML Medicated Liquid Soap) / 1 (120 ML) (salicylic acid 20 MG/ML Topical Solution) / 1 (60 ML) (sulfur 50 MG/ML Topical Solution) } Pack 1372925 GPCK
- {1 (28000 MG) (benzoyl peroxide 0.05 MG/MG Topical Gel) / 1 (127000 MG) (salicylic acid 20 MG/ML Medicated Liquid Soap) / 1 (147 ML) (salicylic acid 20 MG/ML Topical Solution) } Pack 1493509 GPCK
- {1 (3000 MG) (benzoyl peroxide 0.05 MG/MG Topical Gel) / 1 (28000 MG) (salicylic acid 20 MG/ML Medicated Liquid Soap) / 1 (26 ML) (salicylic acid 20 MG/ML Topical Solution) } Pack 1493511 GPCK
- {1 (47 ML) (benzoyl peroxide 50 MG/ML Topical Lotion) / 1 (118 ML) (salicylic acid 20 MG/ML Medicated Liquid Soap) / 1 (148 ML) (salicylic acid 20 MG/ML Topical Solution) } Pack 2191891 GPCK

Showing up to 8 concepts per family — 17 of 17 stored related concepts drawn.

These are official RxNorm vocabulary relationships — how concepts name and organize the same medicine. They do not establish therapeutic equivalence or substitutability: two concepts appearing in one web is never a statement that products can be swapped.

🔀 Generic ⇄ Brand Crosswalk

The same medicine has an unbranded (generic) identity and one or more brand-name identities — each with its own RxCUI. This is a naming relationship in RxNorm, not a statement that any two products are substitutable.

Generic (Clinical) Concepts

Salicylic acid 20 MG/ML Topical Solution SCD · 251577
{1 (28000 MG) (benzoyl peroxide 0.05 MG/MG Topical Gel) / 1 (127000 MG) (salicylic acid 20 MG/ML Medicated Liquid Soap) / 1 (147 ML) (salicylic acid 20 MG/ML Topical Solution) } Pack GPCK · 1493509
{1 (3000 MG) (benzoyl peroxide 0.05 MG/MG Topical Gel) / 1 (28000 MG) (salicylic acid 20 MG/ML Medicated Liquid Soap) / 1 (26 ML) (salicylic acid 20 MG/ML Topical Solution) } Pack GPCK · 1493511
{1 (47 ML) (benzoyl peroxide 50 MG/ML Topical Lotion) / 1 (118 ML) (salicylic acid 20 MG/ML Medicated Liquid Soap) / 1 (148 ML) (salicylic acid 20 MG/ML Topical Solution) } Pack GPCK · 2191891
Salicylic acid 20 MG/ML SCDC · 328925
Salicylic acid Topical Solution SCDF · 238464
Salicylic acid Topical Product SCDG · 1157604
{1 (240 ML) (benzoyl peroxide 25 MG/ML Medicated Liquid Soap) / 1 (120 ML) (salicylic acid 20 MG/ML Topical Solution) / 1 (60 ML) (sulfur 50 MG/ML Topical Solution) } Pack GPCK · 1372925

Brand-Name Concepts

{1 (28000 MG) (benzoyl peroxide 0.05 MG/MG Topical Gel [Clear Proof Acne Treatment]) / 1 (127000 MG) (salicylic acid 20 MG/ML Medicated Liquid Soap [Clear Proof Acne Medication]) / 1 (147 ML) (salicylic acid 20 MG/ML Topical Solution [Clear Proof Acne Medication]) } Pack [Clear Proof Acne System] BPCK · 1493510
{1 (3000 MG) (benzoyl peroxide 0.05 MG/MG Topical Gel [Clear Proof Acne Treatment]) / 1 (28000 MG) (salicylic acid 20 MG/ML Medicated Liquid Soap [Clear Proof Acne Medication]) / 1 (26 ML) (salicylic acid 20 MG/ML Topical Solution [Clear Proof Acne Medication]) } Pack [Clear Proof Acne To-Go System] BPCK · 1493512
Salicylic acid 20 MG/ML [Clear Proof Acne Medication] SBDC · 1491645
Salicylic acid Topical Solution [Clear Proof Acne Medication] SBDF · 1491646
Clear Proof Acne Medication Topical Product SBDG · 1491647
Clear Proof Acne Medication BN · 1491644

📦 FDA Products & Package NDCs

3 products · 4 package NDCs

4 package NDCs map to RxCUI 1491648 in the current snapshot — up to 50 per page. Each linked NDC opens its full package page.

Package NDC	Package	Brand / generic name	Labeler	Marketing start
51531-6743-05	1 BOTTLE, PLASTIC in 1 CARTON (51531-6743-5) / 147 mL in 1...	Clear Proof Blemish Control Toner Acne Medication	Mary Kay Inc.	2013-08-15
51531-6743-09	26 mL in 1 BOTTLE (51531-6743-9)	Clear Proof Blemish Control Toner Acne Medication	Mary Kay Inc.	2013-08-15
51531-8968-00	1 KIT in 1 CARTON (51531-8968-0) * 3 g in 1 TUBE * 26 mL...	Clear Proof Acne System The Go Set	Mary Kay Inc.	2013-08-15
51531-8977-00	1 KIT in 1 CARTON (51531-8977-0) * 147 mL in 1 BOTTLE * 1...	Clear Proof Acne System	Mary Kay Inc.	2013-08-15

Observed labelers: Mary Kay Inc. (4) — this is the FDA-listed mapping footprint, not sales, inventory, availability, or market share.

🗃️ Sources & Limits

Atlas generation902fddb9-e9c1-4004-bf4c-dba4d51037c7

openFDA export observedJul 14, 2026

RxNorm release07/06/2026

Methodology2026-07-full-catalog-v1

A shared RxCUI does not prove interchangeability. Products mapped to the same concept are not thereby equivalent or substitutable — equivalence is a separate, product-level determination.
Listing here does not establish approval or coverage. Appearing in this snapshot is a data observation, not an FDA approval status or a payer coverage decision.
Missing data never means zero. A silent dataset (no price, no billing code, no utilization) means no observation — not that the real-world value is zero.
Counts describe the mapping footprint. Product, package, and labeler counts are the FDA-listed mapping footprint in this snapshot — not sales, inventory, availability, or market share.

This product uses publicly available data from the U.S. National Library of Medicine (NLM), National Institutes of Health, Department of Health and Human Services; NLM is not responsible for the product and does not endorse or recommend this or any other product.

Machine-readable JSON

Reference information about drug-concept identifiers and public regulatory data — not medical advice. Talk to your pharmacist or prescriber about your own medication.