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Acetaminophen 650 MG / dextromethorphan hydrobromide 20 MG / doxylamine succinate 12.5 MG... — RxCUI 1534835

RxNorm drug concept · Semantic clinical drug
RxCUI 1534835 Semantic clinical drug · SCD ● Current RxNorm concept 4 FDA products 3 package NDCs Snapshot Jul 14, 2026

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Compiled from public NLM RxNorm and FDA (openFDA NDC directory) data sources. Editorial policy

What you’re looking at: the standardized identity of one medicine, as the U.S. drug-data system sees it. Below — every FDA-listed product, package code, price benchmark, and billing code that maps to it.

🗂️ Key Facts

RxCUI1534835
Official nameAcetaminophen 650 MG / dextromethorphan hydrobromide 20 MG / doxylamine succinate 12.5 MG / phenylephrine hydrochloride 10 MG Powder for Oral Solution
Concept typeSemantic clinical drug (SCD)
RxNorm statusCurrent RxNorm concept
Also known asAPAP 650 MG / Dextromethorphan Hydrobromide 20 MG / doxylamine succinate 12.5 MG / Phenylephrine Hydrochloride 10 MG Powder for Oral Solution; acetaminophen 650 MG / dextromethorphan HBr 20 MG / doxylamine succinate 12.5 MG / phenylephrine HCl 10 MG Powder for Oral Solution; acetaminophen 650 MG / dextromethorphan hydrobromide 20 MG / doxylamine succinate 12.5 MG / phenylephrine hydrochloride 10 MG Granules for Oral Solution
FDA products mapped4
Package NDCs mapped3
RxNorm release07/06/2026
Snapshot dataJul 14, 2026

📖 Skip the Codes — Read It in Plain English.

Our pharmacist-built guide to Phenylephrine: what it is, how it’s used, side effects, and interactions.

📗 Our plain-language guide HelloPharmacist
  • Yes, it's the same active ingredient, but used in very different ways depending on the form. The nasal spray delivers a tiny amount directly to the nasal lining to temporarily shri...
  • I see phenylephrine in nasal sprays at the pharmacy AND as an IV drug in the hospital — is it really the same medication?
  • You should check with your doctor first. Phenylephrine constricts blood vessels, which can raise blood pressure and put extra strain on the heart — even from a nasal spray. If you...
  • Can I use the nasal spray if I have high blood pressure or heart disease?
📖 Read our full Phenylephrine guide →

🕸️ Concept Web — How Acetaminophen 650 MG / dextromethorphan hydrobro... Connects

One RxCUI never lives alone. Follow the path from the raw ingredient down to the exact strength-and-form concepts FDA products carry — every stop is a real RxNorm concept with its own identifier. Hover or focus any chip for what it means.
This page's concept Acetaminophen 650 MG / dextromethorphan hydrobromide 20 MG / doxylamine succinate 12.5 MG / phenylephrine hydrochloride 10 MG Powder for Oral Solution RxCUI 1534835

Every web starts here: one RxCUI, one fixed meaning in the RxNorm vocabulary.

  1. Ingredients 8

    The active substance itself — no strength, form, or brand attached yet.

    • Acetaminophen 161
    • Dextromethorphan 3289
    • Doxylamine 3642
    • Phenylephrine 8163
    • Acetaminophen / dextromethorphan / doxylamine / phenylephrine 1008701
    • Dextromethorphan hydrobromide 102490
    • Doxylamine succinate 23665
    • Phenylephrine hydrochloride 8164
  2. Dose forms 9

    The ingredient poured into a form — tablet, solution, cream — still without one fixed strength.

    • Acetaminophen / dextromethorphan / doxylamine / phenylephrine Powder for Oral Solution 1804346
    • Acetaminophen / dextromethorphan hydrobromide / doxylamine succinate / phenylephrine hydrochloride Powder for Oral Solution 2646124
    • Acetaminophen / dextromethorphan / doxylamine / phenylephrine Oral Powder Product 1804345
    • Acetaminophen / dextromethorphan / doxylamine / phenylephrine Oral Product 1155896
    • Acetaminophen / dextromethorphan hydrobromide / doxylamine succinate / phenylephrine hydrochloride Oral Powder Product 2660062
    • Acetaminophen / dextromethorphan hydrobromide / doxylamine succinate / phenylephrine hydrochloride Oral Product 2660518
    • Powder for Oral Solution 1540455
    • Oral Powder Product 1294711
    • +1 more in this family
  3. Clinical & branded drugs 4

    Ingredient + strength + dose form. These are the concepts real FDA products actually carry.

    • Acetaminophen 650 MG 315268
    • Dextromethorphan hydrobromide 20 MG 1037200
    • Doxylamine succinate 12.5 MG 1804751
    • Phenylephrine hydrochloride 10 MG 996705
  4. Packs 1

    Fixed collections of drugs packaged and sold together, like dose packs.

Showing up to 8 concepts per family — 21 of 22 stored related concepts drawn.
These are official RxNorm vocabulary relationships — how concepts name and organize the same medicine. They do not establish therapeutic equivalence or substitutability: two concepts appearing in one web is never a statement that products can be swapped.

🔀 Generic ⇄ Brand Crosswalk

The same medicine has an unbranded (generic) identity and one or more brand-name identities — each with its own RxCUI. This is a naming relationship in RxNorm, not a statement that any two products are substitutable.

Generic (Clinical) Concepts

📦 FDA Products & Package NDCs

4 products · 3 package NDCs
3 package NDCs map to RxCUI 1534835 in the current snapshot — up to 50 per page. Each linked NDC opens its full package page.
Package NDC Package Brand / generic name Labeler Marketing start
00280-8272-06 6 PACKET in 1 CARTON (0280-8272-06) / 1 POWDER, FOR SOLUTIO... ALKA SELTZER COLD Cold and Flu plus Congestion Severe Fast Hot Liquid Night Bayer HealthCare LLC. 2026-06-01
00280-8284-12 1 KIT in 1 CARTON (0280-8284-12) * 1 POWDER, FOR SOLUTION... ALKA SELTZER COLD Cold Flu Congestion Severe Fast Hot Liquid Day Night Bayer HealthCare LLC. 2026-06-01
69842-0546-12 1 KIT in 1 CARTON (69842-546-12) * 6 POWDER, FOR SOLUTION... SEVERE COLD PLUS FLU DAYTIME NIGHTTIME CVS Pharmacy,Inc. 2017-07-14
Observed labelers: Bayer HealthCare LLC. (2) · CVS Pharmacy,Inc. (1) — this is the FDA-listed mapping footprint, not sales, inventory, availability, or market share.

🗃️ Sources & Limits

Atlas generation902fddb9-e9c1-4004-bf4c-dba4d51037c7
openFDA export observedJul 14, 2026
RxNorm release07/06/2026
Methodology2026-07-full-catalog-v1
  • A shared RxCUI does not prove interchangeability. Products mapped to the same concept are not thereby equivalent or substitutable — equivalence is a separate, product-level determination.
  • Listing here does not establish approval or coverage. Appearing in this snapshot is a data observation, not an FDA approval status or a payer coverage decision.
  • Missing data never means zero. A silent dataset (no price, no billing code, no utilization) means no observation — not that the real-world value is zero.
  • Counts describe the mapping footprint. Product, package, and labeler counts are the FDA-listed mapping footprint in this snapshot — not sales, inventory, availability, or market share.
This product uses publicly available data from the U.S. National Library of Medicine (NLM), National Institutes of Health, Department of Health and Human Services; NLM is not responsible for the product and does not endorse or recommend this or any other product.

Machine-readable JSON

Reference information about drug-concept identifiers and public regulatory data — not medical advice. Talk to your pharmacist or prescriber about your own medication.