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Aspirin 500 MG / dextromethorphan hydrobromide 10 MG / doxylamine succinate 6.25 MG / phen... — RxCUI 1536503

RxNorm drug concept · Semantic clinical drug
RxCUI 1536503 Semantic clinical drug · SCD ● Current RxNorm concept 4 FDA products 4 package NDCs Snapshot Jul 14, 2026

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Compiled from public NLM RxNorm and FDA (openFDA NDC directory) data sources. Editorial policy

What you’re looking at: the standardized identity of one medicine, as the U.S. drug-data system sees it. Below — every FDA-listed product, package code, price benchmark, and billing code that maps to it.

🗂️ Key Facts

RxCUI1536503
Official nameAspirin 500 MG / dextromethorphan hydrobromide 10 MG / doxylamine succinate 6.25 MG / phenylephrine bitartrate 7.8 MG Effervescent Oral Tablet
Concept typeSemantic clinical drug (SCD)
RxNorm statusCurrent RxNorm concept
Also known asASA 500 MG / Dextromethorphan Hydrobromide 10 MG / doxylamine succinate 6.25 MG / Phenylephrine bitartrate 7.8 MG Effervescent Oral Tablet; aspirin 500 MG / dextromethorphan HBr 10 MG / doxylamine succinate 6.25 MG / phenylephrine bitartrate 7.8 MG Effervescent Oral Tablet
FDA products mapped4
Package NDCs mapped4
RxNorm release07/06/2026
Snapshot dataJul 14, 2026

📖 Skip the Codes — Read It in Plain English.

Our pharmacist-built guide to Phenylephrine: what it is, how it’s used, side effects, and interactions.

📗 Our plain-language guide HelloPharmacist
  • Yes, it's the same active ingredient, but used in very different ways depending on the form. The nasal spray delivers a tiny amount directly to the nasal lining to temporarily shri...
  • I see phenylephrine in nasal sprays at the pharmacy AND as an IV drug in the hospital — is it really the same medication?
  • You should check with your doctor first. Phenylephrine constricts blood vessels, which can raise blood pressure and put extra strain on the heart — even from a nasal spray. If you...
  • Can I use the nasal spray if I have high blood pressure or heart disease?
📖 Read our full Phenylephrine guide →

🕸️ Concept Web — How Aspirin 500 MG / dextromethorphan hydrobromide 1... Connects

One RxCUI never lives alone. Follow the path from the raw ingredient down to the exact strength-and-form concepts FDA products carry — every stop is a real RxNorm concept with its own identifier. Hover or focus any chip for what it means.
This page's concept Aspirin 500 MG / dextromethorphan hydrobromide 10 MG / doxylamine succinate 6.25 MG / phenylephrine bitartrate 7.8 MG Effervescent Oral Tablet RxCUI 1536503

Every web starts here: one RxCUI, one fixed meaning in the RxNorm vocabulary.

  1. Ingredients 8

    The active substance itself — no strength, form, or brand attached yet.

    • Aspirin 1191
    • Dextromethorphan 3289
    • Doxylamine 3642
    • Phenylephrine 8163
    • Aspirin / dextromethorphan / doxylamine / phenylephrine 1053120
    • Dextromethorphan hydrobromide 102490
    • Doxylamine succinate 23665
    • Phenylephrine bitartrate 91167
  2. Dose forms 6

    The ingredient poured into a form — tablet, solution, cream — still without one fixed strength.

    • Aspirin / dextromethorphan / doxylamine / phenylephrine Effervescent Oral Tablet 1536502
    • Aspirin / dextromethorphan hydrobromide / doxylamine succinate / phenylephrine bitartrate Effervescent Oral Tablet 2648302
    • Aspirin / dextromethorphan / doxylamine / phenylephrine Oral Product 1153723
    • Aspirin / dextromethorphan hydrobromide / doxylamine succinate / phenylephrine bitartrate Oral Product 2663463
    • Effervescent Oral Tablet 1535727
    • Oral Product 1151131
  3. Clinical & branded drugs 4

    Ingredient + strength + dose form. These are the concepts real FDA products actually carry.

    • Aspirin 500 MG 315424
    • Dextromethorphan hydrobromide 10 MG 1014455
    • Doxylamine succinate 6.25 MG 1052646
    • Phenylephrine bitartrate 7.8 MG 1536496
  4. Packs 1

    Fixed collections of drugs packaged and sold together, like dose packs.

Showing up to 8 concepts per family — 19 of 19 stored related concepts drawn.
These are official RxNorm vocabulary relationships — how concepts name and organize the same medicine. They do not establish therapeutic equivalence or substitutability: two concepts appearing in one web is never a statement that products can be swapped.

🔀 Generic ⇄ Brand Crosswalk

The same medicine has an unbranded (generic) identity and one or more brand-name identities — each with its own RxCUI. This is a naming relationship in RxNorm, not a statement that any two products are substitutable.

Generic (Clinical) Concepts

📦 FDA Products & Package NDCs

4 products · 4 package NDCs
4 package NDCs map to RxCUI 1536503 in the current snapshot — up to 50 per page. Each linked NDC opens its full package page.
Package NDC Package Brand / generic name Labeler Marketing start
00280-0021-01 10 POUCH in 1 CARTON (0280-0021-01) / 2 TABLET, EFFERVESCEN... Alka-Seltzer Plus Severe Cold Powerfast Fizz Night Bayer HealthCare LLC. 2020-04-01
00280-0025-01 1 KIT in 1 CARTON (0280-0025-01) * 12 TABLET, EFFERVESCENT... Alka-Seltzer Plus Severe Cold PowerFast Fizz Bayer HealthCare LLC. 2020-04-01
00280-1545-20 10 POUCH in 1 CARTON (0280-1545-20) / 2 TABLET, EFFERVESCEN... Alka-Seltzer Plus Cold Night Bayer HealthCare LLC. 2018-09-14
00280-1550-20 1 KIT in 1 CARTON (0280-1550-20) * 6 POUCH in 1 CARTON / 2... Alka-Seltzer Plus Cold Day and Night Bayer HealthCare LLC. 2018-09-14
Observed labelers: Bayer HealthCare LLC. (4) — this is the FDA-listed mapping footprint, not sales, inventory, availability, or market share.

🗃️ Sources & Limits

Atlas generation902fddb9-e9c1-4004-bf4c-dba4d51037c7
openFDA export observedJul 14, 2026
RxNorm release07/06/2026
Methodology2026-07-full-catalog-v1
  • A shared RxCUI does not prove interchangeability. Products mapped to the same concept are not thereby equivalent or substitutable — equivalence is a separate, product-level determination.
  • Listing here does not establish approval or coverage. Appearing in this snapshot is a data observation, not an FDA approval status or a payer coverage decision.
  • Missing data never means zero. A silent dataset (no price, no billing code, no utilization) means no observation — not that the real-world value is zero.
  • Counts describe the mapping footprint. Product, package, and labeler counts are the FDA-listed mapping footprint in this snapshot — not sales, inventory, availability, or market share.
This product uses publicly available data from the U.S. National Library of Medicine (NLM), National Institutes of Health, Department of Health and Human Services; NLM is not responsible for the product and does not endorse or recommend this or any other product.

Machine-readable JSON

Reference information about drug-concept identifiers and public regulatory data — not medical advice. Talk to your pharmacist or prescriber about your own medication.