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Chlorpheniramine maleate 4 MG / dextromethorphan hydrobromide 10 MG / phenylephrine hydroc... — RxCUI 1593105

Name: Chlorpheniramine maleate 4 MG / dextromethorphan hydrobromide 10 MG / phenylephrine h… (RxCUI 1593105)
Creator: Brian Staiger, PharmD

RxNorm drug concept · Semantic clinical drug

RxCUI 1593105 Semantic clinical drug · SCD ● Current RxNorm concept 1 FDA product 1 package NDC Snapshot Jul 14, 2026

This page is curated, coded, and maintained by Dr. Brian Staiger, PharmD

Compiled from public NLM RxNorm and FDA (openFDA NDC directory) data sources. Editorial policy

What you’re looking at: the standardized identity of one medicine, as the U.S. drug-data system sees it. Below — every FDA-listed product, package code, price benchmark, and billing code that maps to it.

🗂️ Key Facts

RxCUI1593105

Official nameChlorpheniramine maleate 4 MG / dextromethorphan hydrobromide 10 MG / phenylephrine hydrochloride 10 MG Oral Tablet

Concept typeSemantic clinical drug (SCD)

RxNorm statusCurrent RxNorm concept

Also known aschlorpheniramine maleate 4 MG / dextromethorphan HBr 10 MG / phenylephrine HCl 10 MG Oral Tablet

FDA products mapped1

Package NDCs mapped1

RxNorm release07/06/2026

Snapshot dataJul 14, 2026

📖 Skip the Codes — Read It in Plain English.

Our pharmacist-built guide to Phenylephrine: what it is, how it’s used, side effects, and interactions.

📗 Our plain-language guide HelloPharmacist

Yes, it's the same active ingredient, but used in very different ways depending on the form. The nasal spray delivers a tiny amount directly to the nasal lining to temporarily shri...
I see phenylephrine in nasal sprays at the pharmacy AND as an IV drug in the hospital — is it really the same medication?
You should check with your doctor first. Phenylephrine constricts blood vessels, which can raise blood pressure and put extra strain on the heart — even from a nasal spray. If you...
Can I use the nasal spray if I have high blood pressure or heart disease?

📖 Read our full Phenylephrine guide →

🕸️ Concept Web — How Chlorpheniramine maleate 4 MG / dextromethorphan... Connects

One RxCUI never lives alone. Follow the path from the raw ingredient down to the exact strength-and-form concepts FDA products carry — every stop is a real RxNorm concept with its own identifier. Hover or focus any chip for what it means.

This page's concept Chlorpheniramine maleate 4 MG / dextromethorphan hydrobromide 10 MG / phenylephrine hydrochloride 10 MG Oral Tablet RxCUI 1593105 Semantic clinical drug · SCD

Every web starts here: one RxCUI, one fixed meaning in the RxNorm vocabulary.

Ingredients 7

The active substance itself — no strength, form, or brand attached yet.
- Chlorpheniramine 2400 IN
- Dextromethorphan 3289 IN
- Phenylephrine 8163 IN
- Chlorpheniramine / dextromethorphan / phenylephrine 689389 MIN
- Chlorpheniramine maleate 142429 PIN
- Dextromethorphan hydrobromide 102490 PIN
- Phenylephrine hydrochloride 8164 PIN
Dose forms 9

The ingredient poured into a form — tablet, solution, cream — still without one fixed strength.
- Chlorpheniramine / dextromethorphan / phenylephrine Oral Tablet 477094 SCDF
- Chlorpheniramine maleate / dextromethorphan hydrobromide / phenylephrine hydrochloride Oral Tablet 2645877 SCDFP
- Chlorpheniramine / dextromethorphan / phenylephrine Oral Product 1154167 SCDG
- Chlorpheniramine / dextromethorphan / phenylephrine Pill 1154168 SCDG
- Chlorpheniramine maleate / dextromethorphan hydrobromide / phenylephrine hydrochloride Oral Product 2661565 SCDGP
- Chlorpheniramine maleate / dextromethorphan hydrobromide / phenylephrine hydrochloride Pill 2660949 SCDGP
- Oral Tablet 317541 DF
- Oral Product 1151131 DFG
- +1 more in this family
Clinical & branded drugs 3

Ingredient + strength + dose form. These are the concepts real FDA products actually carry.
- Chlorpheniramine maleate 4 MG 998253 SCDC
- Dextromethorphan hydrobromide 10 MG 1014455 SCDC
- Phenylephrine hydrochloride 10 MG 996705 SCDC

Showing up to 8 concepts per family — 18 of 19 stored related concepts drawn.

These are official RxNorm vocabulary relationships — how concepts name and organize the same medicine. They do not establish therapeutic equivalence or substitutability: two concepts appearing in one web is never a statement that products can be swapped.

🔀 Generic ⇄ Brand Crosswalk

The same medicine has an unbranded (generic) identity and one or more brand-name identities — each with its own RxCUI. This is a naming relationship in RxNorm, not a statement that any two products are substitutable.

Generic (Clinical) Concepts

Chlorpheniramine maleate 4 MG SCDC · 998253
Dextromethorphan hydrobromide 10 MG SCDC · 1014455
Phenylephrine hydrochloride 10 MG SCDC · 996705
Chlorpheniramine / dextromethorphan / phenylephrine Oral Tablet SCDF · 477094
Chlorpheniramine maleate / dextromethorphan hydrobromide / phenylephrine hydrochloride Oral Tablet SCDFP · 2645877
Chlorpheniramine / dextromethorphan / phenylephrine Oral Product SCDG · 1154167
Chlorpheniramine / dextromethorphan / phenylephrine Pill SCDG · 1154168
Chlorpheniramine maleate / dextromethorphan hydrobromide / phenylephrine hydrochloride Oral Product SCDGP · 2661565
Chlorpheniramine maleate / dextromethorphan hydrobromide / phenylephrine hydrochloride Pill SCDGP · 2660949

📦 FDA Products & Package NDCs

1 product · 1 package NDC

1 package NDC map to RxCUI 1593105 in the current snapshot — up to 50 per page. Each linked NDC opens its full package page.

Package NDC	Package	Brand / generic name	Labeler	Marketing start
00485-0240-01	100 TABLET, COATED in 1 BOTTLE, PLASTIC (0485-0240-01)	ED-A-HIST DM	EDWARDS PHARMACEUTICALS, INC.	2014-10-27

Observed labelers: EDWARDS PHARMACEUTICALS, INC. (1) — this is the FDA-listed mapping footprint, not sales, inventory, availability, or market share.

💲 Pricing (NADAC)

NADAC is CMS's National Average Drug Acquisition Cost — roughly what pharmacies pay to buy the drug. It is an acquisition benchmark, not your copay.

Per ea · median

$0.4261

Range $0.4261–$0.4261 · middle 50% $0.4261–$0.4261 · 1 NDCs

Latest compatible distributions from the CMS NADAC file · dataset watermark 2026-07-10. Prices vary by package and pharmacy; a distribution is shown instead of one misleading number. Rows the dataset is silent on carry no price. No zero-cost conclusion should be drawn.

🗃️ Sources & Limits

Atlas generation902fddb9-e9c1-4004-bf4c-dba4d51037c7

openFDA export observedJul 14, 2026

RxNorm release07/06/2026

Methodology2026-07-full-catalog-v1

A shared RxCUI does not prove interchangeability. Products mapped to the same concept are not thereby equivalent or substitutable — equivalence is a separate, product-level determination.
Listing here does not establish approval or coverage. Appearing in this snapshot is a data observation, not an FDA approval status or a payer coverage decision.
Missing data never means zero. A silent dataset (no price, no billing code, no utilization) means no observation — not that the real-world value is zero.
Counts describe the mapping footprint. Product, package, and labeler counts are the FDA-listed mapping footprint in this snapshot — not sales, inventory, availability, or market share.

This product uses publicly available data from the U.S. National Library of Medicine (NLM), National Institutes of Health, Department of Health and Human Services; NLM is not responsible for the product and does not endorse or recommend this or any other product.

Machine-readable JSON

Reference information about drug-concept identifiers and public regulatory data — not medical advice. Talk to your pharmacist or prescriber about your own medication.