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Acetaminophen 500 MG / caffeine 60 MG / pyrilamine maleate 15 MG Oral Tablet — RxCUI 1597298

RxNorm drug concept · Semantic clinical drug
RxCUI 1597298 Semantic clinical drug · SCD ● Current RxNorm concept 54 FDA products 80 package NDCs Snapshot Jul 14, 2026

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Compiled from public NLM RxNorm and FDA (openFDA NDC directory) data sources. Editorial policy

What you’re looking at: the standardized identity of one medicine, as the U.S. drug-data system sees it. Below — every FDA-listed product, package code, price benchmark, and billing code that maps to it.

🗂️ Key Facts

RxCUI1597298
Official nameAcetaminophen 500 MG / caffeine 60 MG / pyrilamine maleate 15 MG Oral Tablet
Concept typeSemantic clinical drug (SCD)
RxNorm statusCurrent RxNorm concept
Also known asAPAP 500 MG / Caffeine 60 MG / Pyrilamine Maleate 15 MG Oral Tablet
FDA products mapped54
Package NDCs mapped80
RxNorm release07/06/2026
Snapshot dataJul 14, 2026

📖 Skip the Codes — Read It in Plain English.

Our pharmacist-built guide to Acetaminophen Injection: what it is, how it’s used, side effects, and interactions.

📗 Our plain-language guide HelloPharmacist
  • It treats mild to moderate pain, and moderate to severe pain when used with opioid medicines. It also lowers fever. It is given through a vein in a healthcare setting.
  • What is Acetaminophen Injection used for?
  • It is given as an IV infusion over 15 minutes by a healthcare professional. Your dose depends on your age and weight. Your care team follows the label and your prescriber's orders.
  • The most common are nausea and vomiting. Adults may also get headache or trouble sleeping. Children may have constipation or itching.
📖 Read our full Acetaminophen Injection guide →

🕸️ Concept Web — How Acetaminophen 500 MG / caffeine 60 MG / pyrilami... Connects

One RxCUI never lives alone. Follow the path from the raw ingredient down to the exact strength-and-form concepts FDA products carry — every stop is a real RxNorm concept with its own identifier. Hover or focus any chip for what it means.
This page's concept Acetaminophen 500 MG / caffeine 60 MG / pyrilamine maleate 15 MG Oral Tablet RxCUI 1597298

Every web starts here: one RxCUI, one fixed meaning in the RxNorm vocabulary.

  1. Ingredients 5

    The active substance itself — no strength, form, or brand attached yet.

    • Acetaminophen 161
    • Caffeine 1886
    • Pyrilamine 9009
    • Acetaminophen / caffeine / pyrilamine 214137
    • Pyrilamine maleate 82091
  2. Dose forms 9

    The ingredient poured into a form — tablet, solution, cream — still without one fixed strength.

    • Acetaminophen / caffeine / pyrilamine Oral Tablet 375662
    • Acetaminophen / caffeine / pyrilamine maleate Oral Tablet 2648064
    • Acetaminophen / caffeine / pyrilamine Oral Product 1154586
    • Acetaminophen / caffeine / pyrilamine Pill 1154587
    • Acetaminophen / caffeine / pyrilamine maleate Oral Product 2661345
    • Acetaminophen / caffeine / pyrilamine maleate Pill 2659749
    • Oral Tablet 317541
    • Oral Product 1151131
    • +1 more in this family
  3. Clinical & branded drugs 3

    Ingredient + strength + dose form. These are the concepts real FDA products actually carry.

    • Acetaminophen 500 MG 315266
    • Caffeine 60 MG 335998
    • Pyrilamine maleate 15 MG 1052636

Showing up to 8 concepts per family — 16 of 17 stored related concepts drawn.
These are official RxNorm vocabulary relationships — how concepts name and organize the same medicine. They do not establish therapeutic equivalence or substitutability: two concepts appearing in one web is never a statement that products can be swapped.

🔀 Generic ⇄ Brand Crosswalk

The same medicine has an unbranded (generic) identity and one or more brand-name identities — each with its own RxCUI. This is a naming relationship in RxNorm, not a statement that any two products are substitutable.

Generic (Clinical) Concepts

  • Acetaminophen 500 MG SCDC · 315266
  • Caffeine 60 MG SCDC · 335998
  • Pyrilamine maleate 15 MG SCDC · 1052636
  • Acetaminophen / caffeine / pyrilamine Oral Tablet SCDF · 375662
  • Acetaminophen / caffeine / pyrilamine maleate Oral Tablet SCDFP · 2648064
  • Acetaminophen / caffeine / pyrilamine Oral Product SCDG · 1154586
  • Acetaminophen / caffeine / pyrilamine Pill SCDG · 1154587
  • Acetaminophen / caffeine / pyrilamine maleate Oral Product SCDGP · 2661345
  • Acetaminophen / caffeine / pyrilamine maleate Pill SCDGP · 2659749

📦 FDA Products & Package NDCs

54 products · 80 package NDCs
80 package NDCs map to RxCUI 1597298 in the current snapshot — up to 50 per page. Each linked NDC opens its full package page.
Package NDC Package Brand / generic name Labeler Marketing start
00280-8005-01 10 POUCH in 1 CARTON (0280-8005-01) / 2 TABLET in 1 POUCH Midol Complete Bayer HealthCare LLC. 2023-04-26
00280-8005-02 25 POUCH in 1 CARTON (0280-8005-02) / 2 TABLET in 1 POUCH Midol Complete Bayer HealthCare LLC. 2023-04-26
00280-8005-04 2 TABLET in 1 POUCH (0280-8005-04) Midol Complete Bayer HealthCare LLC. 2023-04-26
00280-8005-16 2 BLISTER PACK in 1 CARTON (0280-8005-16) / 8 TABLET in 1 B... Midol Complete Bayer HealthCare LLC. 2014-02-10
00280-8005-24 3 BLISTER PACK in 1 CARTON (0280-8005-24) / 8 TABLET in 1 B... Midol Complete Bayer HealthCare LLC. 2014-02-10
00280-8005-40 1 BOTTLE in 1 CARTON (0280-8005-40) / 40 TABLET in 1 BOTTLE Midol Complete Bayer HealthCare LLC. 2014-02-10
00280-8015-24 3 BLISTER PACK in 1 CARTON (0280-8015-24) / 24 TABLET, COAT... Midol Complete Gelcaps Bayer HealthCare LLC 2014-12-15
00363-0252-21 2 BLISTER PACK in 1 CARTON (0363-0252-21) / 8 TABLET, FILM... Menstrual Relief Maximum Strength Walgreen Company 2002-04-29
00363-2310-24 24 TABLET in 1 PACKAGE (0363-2310-24) Acetaminophen 500mg Caffeine 60mg Pyrilamine maleate 15mg WALGREENS CO. 2019-07-05
00363-3900-22 1 BOTTLE, PLASTIC in 1 CARTON (0363-3900-22) / 48 TABLET, F... Menstrual Pain Relief Walgreen Company 2002-04-29
00363-3909-21 2 BLISTER PACK in 1 CARTON (0363-3909-21) / 8 TABLET, FILM... Menstrual Relief Walgreen Company 2024-03-01
00363-9390-10 1 BOTTLE, PLASTIC in 1 CARTON (0363-9390-10) / 40 TABLET, F... Menstrual Complete Pain Relief Walgreen Company 2022-01-25
00924-6010-02 50 BLISTER PACK in 1 CARTON (0924-6010-02) / 2 TABLET in 1... Midol Complete Acme United Corporation 2023-03-30
11673-0363-64 1 BOTTLE in 1 CARTON (11673-363-64) / 40 TABLET in 1 BOTTLE Multi-Symptom Menstrual Relief TARGET 2025-04-07
11673-0390-10 1 BOTTLE in 1 CARTON (11673-390-10) / 40 TABLET, FILM COATE... Menstrual Relief Target Corporation 2019-04-01
11822-0390-01 1 BOTTLE, PLASTIC in 1 CARTON (11822-0390-1) / 40 TABLET, F... Menstrual Complete Maximum Strength Rite Aid Corporation 2002-04-29
11822-0390-09 1 BOTTLE, PLASTIC in 1 CARTON (11822-0390-9) / 24 TABLET, F... Menstrual Complete Maximum Strength Rite Aid Corporation 2002-04-29
11822-3900-01 1 BOTTLE, PLASTIC in 1 CARTON (11822-3900-1) / 40 TABLET, F... MENSTRUAL COMPLETE Rite Aid Corporation 2024-06-19
11822-3900-08 1 BOTTLE, PLASTIC in 1 CARTON (11822-3900-8) / 24 TABLET, F... MENSTRUAL COMPLETE Rite Aid Corporation 2024-06-13
21130-0930-10 1 BOTTLE, PLASTIC in 1 CARTON (21130-930-10) / 40 TABLET, F... Menstrual Relief Better Living Brands, LLC 2024-04-29
29485-7964-02 25 POUCH in 1 BOX (29485-7964-2) / 2 TABLET in 1 POUCH Midol Complete Lil' Drug Store Products, Inc. 2020-07-10
29485-7964-03 30 POUCH in 1 BOX (29485-7964-3) / 2 TABLET in 1 POUCH Midol Complete Lil' Drug Store Products, Inc. 2015-10-19
29485-7964-04 50 POUCH in 1 BOX (29485-7964-4) / 2 TABLET in 1 POUCH Midol Complete Lil' Drug Store Products, Inc. 2020-07-10
30142-0390-10 1 BOTTLE, PLASTIC in 1 CARTON (30142-390-10) / 40 TABLET, F... Menstrual Complete Kroger Company 2019-06-03
36800-0391-08 1 BOTTLE, PLASTIC in 1 CARTON (36800-391-08) / 24 TABLET, F... Menstrual Complete Topco Associates, LLC 2019-01-01
37808-0389-10 1 BOTTLE, PLASTIC in 1 CARTON (37808-389-10) / 40 TABLET, F... Menstrual Complete H E B 2024-05-03
41163-0390-10 1 BOTTLE, PLASTIC in 1 CARTON (41163-390-10) / 40 TABLET, F... Menstrual Relief Maximum Strength United Natural Foods, Inc. dba UNFI 2002-04-29
41163-0391-10 1 BOTTLE, PLASTIC in 1 CARTON (41163-391-10) / 40 TABLET, F... Menstrual Relief United Natural Foods, Inc. dba UNFI 2024-09-03
49483-0347-24 24 TABLET, FILM COATED in 1 BLISTER PACK (49483-347-24) Comfort-Time Time Cap Labs, Inc 2018-12-14
50269-0007-06 6 BLISTER PACK in 1 BOX (50269-007-06) / 1 POUCH in 1 BLIST... Midol Complete JC World Bell Wholesale Co., Inc. 2019-10-30
50269-0009-06 6 BLISTER PACK in 1 BOX (50269-009-06) / 2 POUCH in 1 BLIST... MIDOL COMPLETE JC World Bell Wholesale Co., Inc. 2019-11-20
50804-0990-08 1 BOTTLE, PLASTIC in 1 CARTON (50804-990-08) / 24 TABLET, F... Menstrual Relief Geiss, Destin & Dunn Inc. 2020-03-24
50844-0390-19 1 BLISTER PACK in 1 CARTON (50844-390-19) / 8 TABLET, FILM... Menstrual Complete Maximum Strength L.N.K. International, Inc. 2002-04-29
50844-0390-21 2 BLISTER PACK in 1 CARTON (50844-390-21) / 8 TABLET, FILM... Menstrual Complete Maximum Strength L.N.K. International, Inc. 2002-04-29
50844-0399-08 1 BOTTLE, PLASTIC in 1 CARTON (50844-399-08) / 24 TABLET, F... Menstrual Complete L.N.K. International, Inc. 2023-07-19
50844-0399-21 2 BLISTER PACK in 1 CARTON (50844-399-21) / 8 TABLET, FILM... Menstrual Complete L.N.K. International, Inc. 2023-07-19
51316-0390-10 1 BOTTLE, PLASTIC in 1 CARTON (51316-390-10) / 40 TABLET, F... MENSTRUAL RELIEF CVS WOONSOCKET PRESCRIPTION CENTER, INCORPORATED 2026-05-11
51316-0390-21 2 BLISTER PACK in 1 CARTON (51316-390-21) / 8 TABLET, FILM... MENSTRUAL RELIEF CVS WOONSOCKET PRESCRIPTION CENTER, INCORPORATED 2026-05-11
53943-0390-10 1 BOTTLE, PLASTIC in 1 CARTON (53943-390-10) / 40 TABLET, F... Menstrual Complete Discount Drug Mart 2020-01-07
55319-0301-21 2 BLISTER PACK in 1 CARTON (55319-301-21) / 8 TABLET, FILM... Menstrual Complete Family Dollar Services Inc 2024-01-25
55758-0326-25 1 BLISTER PACK in 1 CARTON (55758-326-25) / 24 TABLET, COAT... Dolex Fem Pharmadel LLC 2020-10-01
55910-0123-10 1 BOTTLE, PLASTIC in 1 CARTON (55910-123-10) / 40 TABLET, F... Menstrual Relief DOLGENCORP, LLC 2024-02-21
59779-0930-08 3 BLISTER PACK in 1 CARTON (59779-930-08) / 8 TABLET, FILM... Menstrual Relief CVS Pharmacy 2002-04-29
59779-0930-10 1 BOTTLE in 1 CARTON (59779-930-10) / 40 TABLET, FILM COATE... Menstrual Relief CVS Pharmacy 2002-04-29
59779-0930-21 2 BLISTER PACK in 1 CARTON (59779-930-21) / 8 TABLET, FILM... Menstrual Relief CVS Pharmacy 2002-04-29
63868-0032-24 1 BOTTLE, PLASTIC in 1 CARTON (63868-032-24) / 24 TABLET, F... Menstrual Complete Maximum Strength CHAIN DRUG MARKETING ASSOCIATION INC 2002-04-29
66715-6445-02 2 POUCH in 1 CARTON (66715-6445-2) / 2 TABLET in 1 POUCH Midol Complete, Travel BASIX Lil' Drug Store Products, Inc 2022-11-29
66715-6445-07 25 POUCH in 1 CARTON (66715-6445-7) / 2 TABLET in 1 POUCH Midol Complete, Travel BASIX Lil' Drug Store Products, Inc 2022-04-19
66715-6445-08 30 POUCH in 1 CARTON (66715-6445-8) / 2 TABLET in 1 POUCH Midol Complete, Travel BASIX Lil' Drug Store Products, Inc 2022-04-19
66715-9745-02 2 POUCH in 1 CARTON (66715-9745-2) / 2 TABLET in 1 POUCH Midol Complete Lil' Drug Store Products, Inc 2011-12-01
Observed labelers: Bayer HealthCare LLC. (6) · OPMX LLC (5) · Select Consumer Group (5) · L.N.K. International, Inc. (4) · Lil' Drug Store Products, Inc (4) · Rite Aid Corporation (4) · +35 more — this is the FDA-listed mapping footprint, not sales, inventory, availability, or market share.

🗃️ Sources & Limits

Atlas generation902fddb9-e9c1-4004-bf4c-dba4d51037c7
openFDA export observedJul 14, 2026
RxNorm release07/06/2026
Methodology2026-07-full-catalog-v1
  • A shared RxCUI does not prove interchangeability. Products mapped to the same concept are not thereby equivalent or substitutable — equivalence is a separate, product-level determination.
  • Listing here does not establish approval or coverage. Appearing in this snapshot is a data observation, not an FDA approval status or a payer coverage decision.
  • Missing data never means zero. A silent dataset (no price, no billing code, no utilization) means no observation — not that the real-world value is zero.
  • Counts describe the mapping footprint. Product, package, and labeler counts are the FDA-listed mapping footprint in this snapshot — not sales, inventory, availability, or market share.
This product uses publicly available data from the U.S. National Library of Medicine (NLM), National Institutes of Health, Department of Health and Human Services; NLM is not responsible for the product and does not endorse or recommend this or any other product.

Machine-readable JSON

Reference information about drug-concept identifiers and public regulatory data — not medical advice. Talk to your pharmacist or prescriber about your own medication.