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Acetaminophen 650 MG / dextromethorphan hydrobromide 20 MG / phenylephrine hydrochloride 1... — RxCUI 1659967

RxNorm drug concept · Semantic clinical drug
RxCUI 1659967 Semantic clinical drug · SCD ● Current RxNorm concept 8 FDA products 9 package NDCs Snapshot Jul 14, 2026

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Compiled from public NLM RxNorm and FDA (openFDA NDC directory) data sources. Editorial policy

What you’re looking at: the standardized identity of one medicine, as the U.S. drug-data system sees it. Below — every FDA-listed product, package code, price benchmark, and billing code that maps to it.

🗂️ Key Facts

RxCUI1659967
Official nameAcetaminophen 650 MG / dextromethorphan hydrobromide 20 MG / phenylephrine hydrochloride 10 MG Granules for Oral Solution
Concept typeSemantic clinical drug (SCD)
RxNorm statusCurrent RxNorm concept
Also known asacetaminophen 650 MG / dextromethorphan HBr 20 MG / phenylephrine HCl 10 MG Powder for Oral Solution; acetaminophen 650 MG / dextromethorphan HBr 20 MG / phenylephrine HCl 10 MG Granules for Oral Solution; APAP 650 MG / Dextromethorphan Hydrobromide 20 MG / Phenylephrine Hydrochloride 10 MG Granules for Oral Solution
FDA products mapped8
Package NDCs mapped9
RxNorm release07/06/2026
Snapshot dataJul 14, 2026

📖 Skip the Codes — Read It in Plain English.

Our pharmacist-built guide to Phenylephrine: what it is, how it’s used, side effects, and interactions.

📗 Our plain-language guide HelloPharmacist
  • Yes, it's the same active ingredient, but used in very different ways depending on the form. The nasal spray delivers a tiny amount directly to the nasal lining to temporarily shri...
  • I see phenylephrine in nasal sprays at the pharmacy AND as an IV drug in the hospital — is it really the same medication?
  • You should check with your doctor first. Phenylephrine constricts blood vessels, which can raise blood pressure and put extra strain on the heart — even from a nasal spray. If you...
  • Can I use the nasal spray if I have high blood pressure or heart disease?
📖 Read our full Phenylephrine guide →

🕸️ Concept Web — How Acetaminophen 650 MG / dextromethorphan hydrobro... Connects

One RxCUI never lives alone. Follow the path from the raw ingredient down to the exact strength-and-form concepts FDA products carry — every stop is a real RxNorm concept with its own identifier. Hover or focus any chip for what it means.
This page's concept Acetaminophen 650 MG / dextromethorphan hydrobromide 20 MG / phenylephrine hydrochloride 10 MG Granules for Oral Solution RxCUI 1659967

Every web starts here: one RxCUI, one fixed meaning in the RxNorm vocabulary.

  1. Ingredients 6

    The active substance itself — no strength, form, or brand attached yet.

    • Acetaminophen 161
    • Dextromethorphan 3289
    • Phenylephrine 8163
    • Acetaminophen / dextromethorphan / phenylephrine 705259
    • Dextromethorphan hydrobromide 102490
    • Phenylephrine hydrochloride 8164
  2. Dose forms 9

    The ingredient poured into a form — tablet, solution, cream — still without one fixed strength.

    • Acetaminophen / dextromethorphan / phenylephrine Granules for Oral Solution 1659966
    • Acetaminophen / dextromethorphan hydrobromide / phenylephrine hydrochloride Granules for Oral Solution 2646840
    • Acetaminophen / dextromethorphan / phenylephrine Granule Product 1659965
    • Acetaminophen / dextromethorphan / phenylephrine Oral Product 1155918
    • Acetaminophen / dextromethorphan hydrobromide / phenylephrine hydrochloride Granule Product 2660413
    • Acetaminophen / dextromethorphan hydrobromide / phenylephrine hydrochloride Oral Product 2660748
    • Granules for Oral Solution 1540453
    • Granule Product 1294708
    • +1 more in this family
  3. Clinical & branded drugs 3

    Ingredient + strength + dose form. These are the concepts real FDA products actually carry.

    • Acetaminophen 650 MG 315268
    • Dextromethorphan hydrobromide 20 MG 1037200
    • Phenylephrine hydrochloride 10 MG 996705
  4. Packs 1

    Fixed collections of drugs packaged and sold together, like dose packs.

Showing up to 8 concepts per family — 18 of 19 stored related concepts drawn.
These are official RxNorm vocabulary relationships — how concepts name and organize the same medicine. They do not establish therapeutic equivalence or substitutability: two concepts appearing in one web is never a statement that products can be swapped.

🔀 Generic ⇄ Brand Crosswalk

The same medicine has an unbranded (generic) identity and one or more brand-name identities — each with its own RxCUI. This is a naming relationship in RxNorm, not a statement that any two products are substitutable.

Generic (Clinical) Concepts

📦 FDA Products & Package NDCs

8 products · 9 package NDCs
9 package NDCs map to RxCUI 1659967 in the current snapshot — up to 50 per page. Each linked NDC opens its full package page.
Package NDC Package Brand / generic name Labeler Marketing start
00067-6094-01 8 POUCH in 1 CARTON (0067-6094-01) / 1 POWDER, FOR SOLUTION... Theraflu PowerPods Daytime Severe Cold Haleon US Holdings LLC 2018-07-28
00067-6094-03 1 POUCH in 1 CARTON (0067-6094-03) / 1 POWDER, FOR SOLUTION... Theraflu PowerPods Daytime Severe Cold Haleon US Holdings LLC 2019-01-20
00067-6800-02 6 POWDER in 1 CARTON (0067-6800-02) Theraflu Severe Cold Relief Daytime Berry Burst Haleon US Holdings LLC 2022-01-20
00067-7917-06 6 PACKET in 1 CARTON (0067-7917-06) / 1 POWDER, FOR SOLUTIO... Theraflu Daytime Severe Cold and Cough Haleon US Holdings LLC 2012-09-24
00067-8211-01 6 PACKET in 1 CARTON (0067-8211-01) / 1 POWDER, FOR SOLUTIO... Theraflu Severe Cold Relief Daytime with Honey Ginger Flavor Haleon US Holdings LLC 2023-05-01
11673-0542-12 1 KIT in 1 CARTON (11673-542-12) * 6 POWDER, FOR SOLUTION... daytime severe cold and cough and nighttime severe cold and cough Target Corporation 2017-07-31
55758-0384-06 6 GRANULE, FOR SOLUTION in 1 CARTON (55758-384-06) SanaTos Severe Cold and Cough Daytime Pharmadel LLC 2024-03-31
67091-0322-06 6 PACKET in 1 CARTON (67091-322-06) / 1 POWDER, FOR SOLUTIO... Severe Cold and Cough Daytime WinCo Foods, LLC 2018-08-01
68163-0540-06 6 POWDER, FOR SOLUTION in 1 CARTON (68163-540-06) severe cold and cough daytime RARITAN PHARMACEUTICALS INC 2019-03-14
Observed labelers: Haleon US Holdings LLC (5) · Pharmadel LLC (1) · RARITAN PHARMACEUTICALS INC (1) · Target Corporation (1) · WinCo Foods, LLC (1) — this is the FDA-listed mapping footprint, not sales, inventory, availability, or market share.

🗃️ Sources & Limits

Atlas generation902fddb9-e9c1-4004-bf4c-dba4d51037c7
openFDA export observedJul 14, 2026
RxNorm release07/06/2026
Methodology2026-07-full-catalog-v1
  • A shared RxCUI does not prove interchangeability. Products mapped to the same concept are not thereby equivalent or substitutable — equivalence is a separate, product-level determination.
  • Listing here does not establish approval or coverage. Appearing in this snapshot is a data observation, not an FDA approval status or a payer coverage decision.
  • Missing data never means zero. A silent dataset (no price, no billing code, no utilization) means no observation — not that the real-world value is zero.
  • Counts describe the mapping footprint. Product, package, and labeler counts are the FDA-listed mapping footprint in this snapshot — not sales, inventory, availability, or market share.
This product uses publicly available data from the U.S. National Library of Medicine (NLM), National Institutes of Health, Department of Health and Human Services; NLM is not responsible for the product and does not endorse or recommend this or any other product.

Machine-readable JSON

Reference information about drug-concept identifiers and public regulatory data — not medical advice. Talk to your pharmacist or prescriber about your own medication.