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Dorzolamide 20 MG/ML / timolol 5 MG/ML Ophthalmic Solution — RxCUI 1923432

Name: Dorzolamide 20 MG/ML / timolol 5 MG/ML Ophthalmic Solution (RxCUI 1923432)
Creator: Brian Staiger, PharmD

RxNorm drug concept · Semantic clinical drug

RxCUI 1923432 Semantic clinical drug · SCD ● Current RxNorm concept 17 FDA products 20 package NDCs Snapshot Jul 14, 2026

This page is curated, coded, and maintained by Dr. Brian Staiger, PharmD

Compiled from public NLM RxNorm and FDA (openFDA NDC directory) data sources. Editorial policy

What you’re looking at: the standardized identity of one medicine, as the U.S. drug-data system sees it. Below — every FDA-listed product, package code, price benchmark, and billing code that maps to it.

🗂️ Key Facts

RxCUI1923432

Official nameDorzolamide 20 MG/ML / timolol 5 MG/ML Ophthalmic Solution

Concept typeSemantic clinical drug (SCD)

RxNorm statusCurrent RxNorm concept

Also known asdorzolamide 2 % / timolol 0.5 % Ophthalmic Solution; dorzolamide HCl 2 % / timolol maleate 0.5 % Ophthalmic Solution; dorzolamide 20 MG/ML (as dorzolamide HCl 22.26 MG/ML) / timolol 5 MG/ML (as timolol maleate 6.83 MG/ML) Ophthalmic Solution

FDA products mapped17

Package NDCs mapped20

Reported Medicaid activity (SDUD)250,948 prescriptions · 51 state & territory Medicaid programs · latest period Q4 2025

RxNorm release07/06/2026

Snapshot dataJul 14, 2026

📖 Skip the Codes — Read It in Plain English.

Our pharmacist-built guide to Timolol Ophthalmic: what it is, how it’s used, side effects, and interactions.

📗 Our plain-language guide HelloPharmacist

It lowers high pressure inside your eye. Doctors prescribe it for ocular hypertension and open-angle glaucoma. Keeping eye pressure down helps protect your optic nerve and vision.
Put one drop in the affected eye(s) as directed. The gel-forming solution is used once a day. Turn the closed bottle upside down and shake it once first. If you use other eye drops...
Stinging or burning when the drop goes in is the most common. You may also have blurred vision, itching, redness or headache. These are usually eye-related, but tell your doctor if...
Get help for wheezing, trouble breathing, a very slow or irregular heartbeat, fainting, new swelling, or signs of a serious allergic reaction. Even though it is an eye drop, some o...

📖 Read our full Timolol Ophthalmic guide →

🕸️ Concept Web — How Dorzolamide 20 MG/ML / timolol 5 MG/ML Ophthalmi... Connects

One RxCUI never lives alone. Follow the path from the raw ingredient down to the exact strength-and-form concepts FDA products carry — every stop is a real RxNorm concept with its own identifier. Hover or focus any chip for what it means.

This page's concept Dorzolamide 20 MG/ML / timolol 5 MG/ML Ophthalmic Solution RxCUI 1923432 Semantic clinical drug · SCD

Every web starts here: one RxCUI, one fixed meaning in the RxNorm vocabulary.

Ingredients 3

The active substance itself — no strength, form, or brand attached yet.
- Dorzolamide 60207 IN
- Timolol 10600 IN
- Dorzolamide / timolol 662263 MIN
Brand names 1

The same medicine's trade names. A brand name alone says nothing about strength or form.
- Cosopt 216253 BN
Dose forms 6

The ingredient poured into a form — tablet, solution, cream — still without one fixed strength.
- Dorzolamide / timolol Ophthalmic Solution 377452 SCDF
- Dorzolamide / timolol Ophthalmic Product 1160643 SCDG
- Dorzolamide / timolol Ophthalmic Solution [Cosopt] 363756 SBDF
- Cosopt Ophthalmic Product 1171614 SBDG
- Ophthalmic Solution 7670 DF
- Ophthalmic Product 1151135 DFG
Clinical & branded drugs 4

Ingredient + strength + dose form. These are the concepts real FDA products actually carry.
- Dorzolamide 20 MG/ML 328229 SCDC
- Timolol 5 MG/ML 328742 SCDC
- Dorzolamide 20 MG/ML / timolol 5 MG/ML Ophthalmic Solution [Cosopt] 1923433 SBD
- Dorzolamide 20 MG/ML / timolol 5 MG/ML [Cosopt] 573193 SBDC

Showing up to 8 concepts per family — 14 of 14 stored related concepts drawn.

These are official RxNorm vocabulary relationships — how concepts name and organize the same medicine. They do not establish therapeutic equivalence or substitutability: two concepts appearing in one web is never a statement that products can be swapped.

🔀 Generic ⇄ Brand Crosswalk

The same medicine has an unbranded (generic) identity and one or more brand-name identities — each with its own RxCUI. This is a naming relationship in RxNorm, not a statement that any two products are substitutable.

Generic (Clinical) Concepts

Dorzolamide 20 MG/ML SCDC · 328229
Timolol 5 MG/ML SCDC · 328742
Dorzolamide / timolol Ophthalmic Solution SCDF · 377452
Dorzolamide / timolol Ophthalmic Product SCDG · 1160643

Brand-Name Concepts

Dorzolamide 20 MG/ML / timolol 5 MG/ML Ophthalmic Solution [Cosopt] SBD · 1923433
Dorzolamide 20 MG/ML / timolol 5 MG/ML [Cosopt] SBDC · 573193
Dorzolamide / timolol Ophthalmic Solution [Cosopt] SBDF · 363756
Cosopt Ophthalmic Product SBDG · 1171614
Cosopt BN · 216253

📦 FDA Products & Package NDCs

17 products · 20 package NDCs

20 package NDCs map to RxCUI 1923432 in the current snapshot — up to 50 per page. Each linked NDC opens its full package page.

Package NDC	Package	Brand / generic name	Labeler	Marketing start
14445-0405-10	1 BOTTLE, DISPENSING in 1 CARTON (14445-405-10) / 10 mL in...	DORZOLAMIDE HYDROCHLORIDE TIMOLOL MALETAE	Indoco Remedies Limited	2021-05-14
24208-0486-05	1 BOTTLE, DROPPER in 1 CARTON (24208-486-05) / 5 mL in 1 BO...	Dorzolamide Hydrochloride and Timolol Maleate	Bausch & Lomb Incorporated	2009-07-14
24208-0486-10	1 BOTTLE, DROPPER in 1 CARTON (24208-486-10) / 10 mL in 1 B...	Dorzolamide Hydrochloride and Timolol Maleate	Bausch & Lomb Incorporated	2009-07-14
42571-0147-26	1 BOTTLE in 1 CARTON (42571-147-26) / 10 mL in 1 BOTTLE	Dorzolamide Hydrochloride and Timolol Maleate ophthalmic Solution	Micro Labs Limited	2020-06-15
46708-0553-10	1 BOTTLE in 1 CARTON (46708-553-10) / 10 mL in 1 BOTTLE	Dorzolamide Hydrochloride and Timolol Maleate Ophthalmic Solution	Alembic Pharmaceuticals Limited	2021-05-04
50090-6371-00	1 BOTTLE, DROPPER in 1 CARTON (50090-6371-0) / 10 mL in 1 B...	Dorzolamide Hydrochloride and Timolol Maleate	A-S Medication Solutions	2023-02-13
61314-0030-01	5 mL in 1 BOTTLE (61314-030-01)	Dorzolamide Hydrochloride and Timolol Maleate	Sandoz Inc	2010-01-02
61314-0030-02	10 mL in 1 BOTTLE (61314-030-02)	Dorzolamide Hydrochloride and Timolol Maleate	Sandoz Inc	2010-01-02
62332-0553-10	1 BOTTLE in 1 CARTON (62332-553-10) / 10 mL in 1 BOTTLE	Dorzolamide Hydrochloride and Timolol Maleate Ophthalmic Solution	Alembic Pharmaceuticals Inc.	2021-05-04
64950-0390-60	60 VIAL, SINGLE-DOSE in 1 CARTON (64950-390-60) / .2 mL in...	Dorzolamide Hydrochloride and Timolol Maleate	Genus Lifesciences	2025-08-01
65862-0946-01	1 BOTTLE, DROPPER in 1 CARTON (65862-946-01) / 10 mL in 1 B...	Dorzolamide Hydrochloride and Timolol Maleate	Aurobindo Pharma Limited	2021-05-14
68083-0490-01	1 BOTTLE in 1 CARTON (68083-490-01) / 10 mL in 1 BOTTLE	Dorzolamide Hydrochloride and Timolol Maleate	Gland Pharma Limited	2022-09-19
69315-0305-05	1 BOTTLE, PLASTIC in 1 CARTON (69315-305-05) / 5 mL in 1 BO...	Dorzolamide and Timolol	Leading Pharma, LLC	2017-05-18
69315-0305-10	1 BOTTLE, PLASTIC in 1 CARTON (69315-305-10) / 10 mL in 1 B...	Dorzolamide and Timolol	Leading Pharma, LLC	2017-05-18
70069-0051-01	1 BOTTLE in 1 CARTON (70069-051-01) / 10 mL in 1 BOTTLE	DORZOLAMIDE HYDROCHLORIDE and TIMOLOL MALEATE	Somerset Therapeutics, LLC	2019-06-25
71921-0226-10	1 BOTTLE, DISPENSING in 1 CARTON (71921-226-10) / 10 mL in...	DORZOLAMIDE HYDROCHLORIDE TIMOLOL MALEATE	Florida Pharmaceutical Products, LLC	2023-08-16
72162-2166-02	1 BOTTLE, DROPPER in 1 CARTON (72162-2166-2) / 10 mL in 1 B...	Dorzolamide Hydrochloride and Timolol Maleate	Bryant Ranch Prepack	2023-12-07
72162-2184-02	10 mL in 1 BOTTLE (72162-2184-2)	Dorzolamide Hydrochloride and Timolol Maleate	Bryant Ranch Prepack	2023-12-07
72162-2381-02	1 BOTTLE in 1 CARTON (72162-2381-2) / 10 mL in 1 BOTTLE	Dorzolamide Hydrochloride and Timolol Maleate ophthalmic Solution	Bryant Ranch Prepack	2020-06-15
82584-0605-10	1 BOTTLE, DROPPER in 1 CARTON (82584-605-10) / 10 mL in 1 B...	COSOPT	Thea Pharma Inc.	2022-11-10

Observed labelers: Bryant Ranch Prepack (3) · Bausch & Lomb Incorporated (2) · Leading Pharma, LLC (2) · Sandoz Inc (2) · A-S Medication Solutions (1) · Alembic Pharmaceuticals Inc. (1) · +9 more — this is the FDA-listed mapping footprint, not sales, inventory, availability, or market share.

🗃️ Sources & Limits

Atlas generation902fddb9-e9c1-4004-bf4c-dba4d51037c7

openFDA export observedJul 14, 2026

RxNorm release07/06/2026

Methodology2026-07-full-catalog-v1

A shared RxCUI does not prove interchangeability. Products mapped to the same concept are not thereby equivalent or substitutable — equivalence is a separate, product-level determination.
Listing here does not establish approval or coverage. Appearing in this snapshot is a data observation, not an FDA approval status or a payer coverage decision.
Missing data never means zero. A silent dataset (no price, no billing code, no utilization) means no observation — not that the real-world value is zero.
Counts describe the mapping footprint. Product, package, and labeler counts are the FDA-listed mapping footprint in this snapshot — not sales, inventory, availability, or market share.

This product uses publicly available data from the U.S. National Library of Medicine (NLM), National Institutes of Health, Department of Health and Human Services; NLM is not responsible for the product and does not endorse or recommend this or any other product.

Machine-readable JSON

Reference information about drug-concept identifiers and public regulatory data — not medical advice. Talk to your pharmacist or prescriber about your own medication.