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Captopril 25 MG / hydrochlorothiazide 25 MG Oral Tablet — RxCUI 197437

RxNorm drug concept · Semantic clinical drug
RxCUI 197437 Semantic clinical drug · SCD ● Current RxNorm concept 4 FDA products 4 package NDCs Snapshot Jul 14, 2026

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Compiled from public NLM RxNorm and FDA (openFDA NDC directory) data sources. Editorial policy

What you’re looking at: the standardized identity of one medicine, as the U.S. drug-data system sees it. Below — every FDA-listed product, package code, price benchmark, and billing code that maps to it.

🗂️ Key Facts

RxCUI197437
Official nameCaptopril 25 MG / hydrochlorothiazide 25 MG Oral Tablet
Concept typeSemantic clinical drug (SCD)
RxNorm statusCurrent RxNorm concept
Also known ascaptopril 25 MG / HCTZ 25 MG Oral Tablet
FDA products mapped4
Package NDCs mapped4
RxNorm release07/06/2026
Snapshot dataJul 14, 2026

📖 Skip the Codes — Read It in Plain English.

Our pharmacist-built guide to Captopril and Hydrochlorothiazide: what it is, how it’s used, side effects, and interactions.

📗 Our plain-language guide HelloPharmacist
  • The captopril part of this tablet is absorbed much better on an empty stomach — food can reduce absorption by 30 to 40%. Taking it an hour before a meal ensures your body gets the...
  • Why do I need to take this pill an hour before eating?
  • Yes, a dry, persistent cough is one of the most recognized side effects of ACE inhibitors like captopril. It affects a small percentage of people and doesn't mean anything is wrong...
  • I've developed a dry cough since starting this. Is that normal?
📖 Read our full Captopril and Hydrochlorothiazide guide →

🕸️ Concept Web — How Captopril 25 MG / hydrochlorothiazide 25 MG Oral... Connects

One RxCUI never lives alone. Follow the path from the raw ingredient down to the exact strength-and-form concepts FDA products carry — every stop is a real RxNorm concept with its own identifier. Hover or focus any chip for what it means.
This page's concept Captopril 25 MG / hydrochlorothiazide 25 MG Oral Tablet RxCUI 197437

Every web starts here: one RxCUI, one fixed meaning in the RxNorm vocabulary.

  1. Ingredients 3

    The active substance itself — no strength, form, or brand attached yet.

    • Captopril 1998
    • Hydrochlorothiazide 5487
    • Captopril / hydrochlorothiazide 214357
  2. Dose forms 6

    The ingredient poured into a form — tablet, solution, cream — still without one fixed strength.

    • Captopril / hydrochlorothiazide Oral Tablet 371253
    • Captopril / hydrochlorothiazide Oral Product 1155750
    • Captopril / hydrochlorothiazide Pill 1155751
    • Oral Tablet 317541
    • Oral Product 1151131
    • Pill 1151133
  3. Clinical & branded drugs 2

    Ingredient + strength + dose form. These are the concepts real FDA products actually carry.

    • Captopril 25 MG 315561
    • Hydrochlorothiazide 25 MG 316049

Showing up to 8 concepts per family — 11 of 11 stored related concepts drawn.
These are official RxNorm vocabulary relationships — how concepts name and organize the same medicine. They do not establish therapeutic equivalence or substitutability: two concepts appearing in one web is never a statement that products can be swapped.

🔀 Generic ⇄ Brand Crosswalk

The same medicine has an unbranded (generic) identity and one or more brand-name identities — each with its own RxCUI. This is a naming relationship in RxNorm, not a statement that any two products are substitutable.

Generic (Clinical) Concepts

  • Captopril 25 MG SCDC · 315561
  • Hydrochlorothiazide 25 MG SCDC · 316049
  • Captopril / hydrochlorothiazide Oral Tablet SCDF · 371253
  • Captopril / hydrochlorothiazide Oral Product SCDG · 1155750
  • Captopril / hydrochlorothiazide Pill SCDG · 1155751

📦 FDA Products & Package NDCs

4 products · 4 package NDCs
4 package NDCs map to RxCUI 197437 in the current snapshot — up to 50 per page. Each linked NDC opens its full package page.
Package NDC Package Brand / generic name Labeler Marketing start
16571-0827-09 90 TABLET in 1 BOTTLE (16571-827-09) CAPTOPRIL AND HYDROCHLOROTHIAZIDE Rising Pharma Holdings, Inc. 2023-02-14
16571-0828-09 90 TABLET in 1 BOTTLE (16571-828-09) CAPTOPRIL AND HYDROCHLOROTHIAZIDE Rising Pharma Holdings, Inc. 2023-02-14
16571-0829-09 90 TABLET in 1 BOTTLE (16571-829-09) CAPTOPRIL AND HYDROCHLOROTHIAZIDE Rising Pharma Holdings, Inc. 2023-02-14
16571-0830-09 90 TABLET in 1 BOTTLE (16571-830-09) CAPTOPRIL AND HYDROCHLOROTHIAZIDE Rising Pharma Holdings, Inc. 2023-02-14
Observed labelers: Rising Pharma Holdings, Inc. (4) — this is the FDA-listed mapping footprint, not sales, inventory, availability, or market share.

🗃️ Sources & Limits

Atlas generation902fddb9-e9c1-4004-bf4c-dba4d51037c7
openFDA export observedJul 14, 2026
RxNorm release07/06/2026
Methodology2026-07-full-catalog-v1
  • A shared RxCUI does not prove interchangeability. Products mapped to the same concept are not thereby equivalent or substitutable — equivalence is a separate, product-level determination.
  • Listing here does not establish approval or coverage. Appearing in this snapshot is a data observation, not an FDA approval status or a payer coverage decision.
  • Missing data never means zero. A silent dataset (no price, no billing code, no utilization) means no observation — not that the real-world value is zero.
  • Counts describe the mapping footprint. Product, package, and labeler counts are the FDA-listed mapping footprint in this snapshot — not sales, inventory, availability, or market share.
This product uses publicly available data from the U.S. National Library of Medicine (NLM), National Institutes of Health, Department of Health and Human Services; NLM is not responsible for the product and does not endorse or recommend this or any other product.

Machine-readable JSON

Reference information about drug-concept identifiers and public regulatory data — not medical advice. Talk to your pharmacist or prescriber about your own medication.