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Fluorouracil 50 MG/ML Topical Cream [Efudex] — RxCUI 213045

RxNorm drug concept · Semantic branded drug
RxCUI 213045 Semantic branded drug · SBD ● Current RxNorm concept 1 FDA product 1 package NDC Snapshot Jul 14, 2026

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Compiled from public NLM RxNorm and FDA (openFDA NDC directory) data sources. Editorial policy

What you’re looking at: the standardized identity of one medicine, as the U.S. drug-data system sees it. Below — every FDA-listed product, package code, price benchmark, and billing code that maps to it.

🗂️ Key Facts

RxCUI213045
Official nameFluorouracil 50 MG/ML Topical Cream [Efudex]
Concept typeSemantic branded drug (SBD)
RxNorm statusCurrent RxNorm concept
Also known asEfudex 5 % Topical Cream; 5-5-fluorouracil 50 MG/ML Topical Cream [Efudex]; 5-FU 50 MG/ML Topical Cream [Efudex]; Efudex 50 MG/ML Topical Cream
FDA products mapped1
Package NDCs mapped1
Reported Medicaid activity (SDUD)88 prescriptions · 2 state & territory Medicaid programs · latest period Q4 2025
RxNorm release07/06/2026
Snapshot dataJul 14, 2026

📖 Skip the Codes — Read It in Plain English.

Our pharmacist-built guide to Fluorouracil Topical: what it is, how it’s used, side effects, and interactions.

📗 Our plain-language guide HelloPharmacist
  • It treats actinic keratoses, which are rough, sun-damaged skin patches. The 5% strength is also used for superficial basal cell carcinomas when usual treatments are impractical. Su...
  • Apply it as directed, usually twice daily, to cover the lesions. Use a nonmetal applicator or glove if you can. If you use your fingers, wash your hands right away. Follow your pre...
  • Yes. Redness, dryness, crusting, itching, burning, swelling, and raw spots are expected. They usually peak around the end of treatment and fade within about 4 weeks after stopping...
  • No. It can harm a fetus, and miscarriage and birth defects have been reported. If you could become pregnant, use effective contraception. For Tolak Cream, continue it for one month...
📖 Read our full Fluorouracil Topical guide →

🕸️ Concept Web — How Fluorouracil 50 MG/ML Topical Cream [Efudex] Connects

One RxCUI never lives alone. Follow the path from the raw ingredient down to the exact strength-and-form concepts FDA products carry — every stop is a real RxNorm concept with its own identifier. Hover or focus any chip for what it means.
This page's concept Fluorouracil 50 MG/ML Topical Cream [Efudex] RxCUI 213045

Every web starts here: one RxCUI, one fixed meaning in the RxNorm vocabulary.

  1. Ingredients 1

    The active substance itself — no strength, form, or brand attached yet.

    • Fluorouracil 4492
  2. Brand names 1

    The same medicine's trade names. A brand name alone says nothing about strength or form.

    • Efudex 224945
  3. Dose forms 6

    The ingredient poured into a form — tablet, solution, cream — still without one fixed strength.

    • Fluorouracil Topical Cream 377700
    • Fluorouracil Topical Product 1160832
    • Fluorouracil Topical Cream [Efudex] 362219
    • Efudex Topical Product 1173846
    • Topical Cream 316982
    • Topical Product 1151122
  4. Clinical & branded drugs 3

    Ingredient + strength + dose form. These are the concepts real FDA products actually carry.

Showing up to 8 concepts per family — 11 of 11 stored related concepts drawn.
These are official RxNorm vocabulary relationships — how concepts name and organize the same medicine. They do not establish therapeutic equivalence or substitutability: two concepts appearing in one web is never a statement that products can be swapped.

🔀 Generic ⇄ Brand Crosswalk

The same medicine has an unbranded (generic) identity and one or more brand-name identities — each with its own RxCUI. This is a naming relationship in RxNorm, not a statement that any two products are substitutable.

Generic (Clinical) Concepts

  • Fluorouracil 50 MG/ML Topical Cream SCD · 105583
  • Fluorouracil 50 MG/ML SCDC · 315950
  • Fluorouracil Topical Cream SCDF · 377700
  • Fluorouracil Topical Product SCDG · 1160832

Brand-Name Concepts

  • Fluorouracil 50 MG/ML [Efudex] SBDC · 572984
  • Fluorouracil Topical Cream [Efudex] SBDF · 362219
  • Efudex Topical Product SBDG · 1173846
  • Efudex BN · 224945

📦 FDA Products & Package NDCs

1 product · 1 package NDC
1 package NDC map to RxCUI 213045 in the current snapshot — up to 50 per page. Each linked NDC opens its full package page.
Package NDC Package Brand / generic name Labeler Marketing start
00187-3204-47 1 TUBE in 1 CARTON (0187-3204-47) / 40 g in 1 TUBE Efudex Bausch Health US, LLC 1970-07-29
Observed labelers: Bausch Health US, LLC (1) — this is the FDA-listed mapping footprint, not sales, inventory, availability, or market share.

🗃️ Sources & Limits

Atlas generation902fddb9-e9c1-4004-bf4c-dba4d51037c7
openFDA export observedJul 14, 2026
RxNorm release07/06/2026
Methodology2026-07-full-catalog-v1
  • A shared RxCUI does not prove interchangeability. Products mapped to the same concept are not thereby equivalent or substitutable — equivalence is a separate, product-level determination.
  • Listing here does not establish approval or coverage. Appearing in this snapshot is a data observation, not an FDA approval status or a payer coverage decision.
  • Missing data never means zero. A silent dataset (no price, no billing code, no utilization) means no observation — not that the real-world value is zero.
  • Counts describe the mapping footprint. Product, package, and labeler counts are the FDA-listed mapping footprint in this snapshot — not sales, inventory, availability, or market share.
This product uses publicly available data from the U.S. National Library of Medicine (NLM), National Institutes of Health, Department of Health and Human Services; NLM is not responsible for the product and does not endorse or recommend this or any other product.

Machine-readable JSON

Reference information about drug-concept identifiers and public regulatory data — not medical advice. Talk to your pharmacist or prescriber about your own medication.