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Trifarotene 0.05 MG/ML Topical Cream — RxCUI 2205642

RxNorm drug concept · Semantic clinical drug
RxCUI 2205642 Semantic clinical drug · SCD ● Current RxNorm concept 1 FDA product 2 package NDCs Snapshot Jul 14, 2026

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Compiled from public NLM RxNorm and FDA (openFDA NDC directory) data sources. Editorial policy

What you’re looking at: the standardized identity of one medicine, as the U.S. drug-data system sees it. Below — every FDA-listed product, package code, price benchmark, and billing code that maps to it.

🗂️ Key Facts

RxCUI2205642
Official nameTrifarotene 0.05 MG/ML Topical Cream
Concept typeSemantic clinical drug (SCD)
RxNorm statusCurrent RxNorm concept
Also known astrifarotene 0.005 % Topical Cream
FDA products mapped1
Package NDCs mapped2
Reported Medicaid activity (SDUD)3,012 prescriptions · 16 state & territory Medicaid programs · latest period Q4 2025
RxNorm release07/06/2026
Snapshot dataJul 14, 2026

📖 Skip the Codes — Read It in Plain English.

Our pharmacist-built guide to Trifarotene Topical: what it is, how it’s used, side effects, and interactions.

📗 Our plain-language guide HelloPharmacist
  • Aklief Cream is a prescription treatment for acne vulgaris — the common kind of acne. It's approved for people aged 9 and older, and you can use it on your face, chest, shoulders,...
  • Apply a thin layer to your affected skin once a day, in the evening, after washing and fully drying your skin. One pump from the dispenser is enough for the face; two pumps cover t...
  • How do I apply it, and when should I use it?
  • Yes, that's very common, especially in the first four weeks. Redness, peeling, dryness, stinging, or a burning feeling are the most frequently reported side effects. The good news...
📖 Read our full Trifarotene Topical guide →

🕸️ Concept Web — How Trifarotene 0.05 MG/ML Topical Cream Connects

One RxCUI never lives alone. Follow the path from the raw ingredient down to the exact strength-and-form concepts FDA products carry — every stop is a real RxNorm concept with its own identifier. Hover or focus any chip for what it means.
This page's concept Trifarotene 0.05 MG/ML Topical Cream RxCUI 2205642

Every web starts here: one RxCUI, one fixed meaning in the RxNorm vocabulary.

  1. Ingredients 1

    The active substance itself — no strength, form, or brand attached yet.

    • Trifarotene 2205637
  2. Brand names 1

    The same medicine's trade names. A brand name alone says nothing about strength or form.

    • Aklief 2205643
  3. Dose forms 6

    The ingredient poured into a form — tablet, solution, cream — still without one fixed strength.

    • Trifarotene Topical Cream 2205641
    • Trifarotene Topical Product 2205640
    • Trifarotene Topical Cream [Aklief] 2205645
    • Aklief Topical Product 2205646
    • Topical Cream 316982
    • Topical Product 1151122
  4. Clinical & branded drugs 3

    Ingredient + strength + dose form. These are the concepts real FDA products actually carry.

Showing up to 8 concepts per family — 11 of 11 stored related concepts drawn.
These are official RxNorm vocabulary relationships — how concepts name and organize the same medicine. They do not establish therapeutic equivalence or substitutability: two concepts appearing in one web is never a statement that products can be swapped.

🔀 Generic ⇄ Brand Crosswalk

The same medicine has an unbranded (generic) identity and one or more brand-name identities — each with its own RxCUI. This is a naming relationship in RxNorm, not a statement that any two products are substitutable.

Generic (Clinical) Concepts

  • Trifarotene 0.05 MG/ML SCDC · 2205639
  • Trifarotene Topical Cream SCDF · 2205641
  • Trifarotene Topical Product SCDG · 2205640

Brand-Name Concepts

📦 FDA Products & Package NDCs

1 product · 2 package NDCs
2 package NDCs map to RxCUI 2205642 in the current snapshot — up to 50 per page. Each linked NDC opens its full package page.
Package NDC Package Brand / generic name Labeler Marketing start
00299-5935-02 1 TUBE in 1 BLISTER PACK (0299-5935-02) / 2 g in 1 TUBE AKLIEF Galderma Laboratories, L.P. 2019-10-04
00299-5935-45 1 BOTTLE, PUMP in 1 CARTON (0299-5935-45) / 45 g in 1 BOTTL... AKLIEF Galderma Laboratories, L.P. 2019-10-04
Observed labelers: Galderma Laboratories, L.P. (2) — this is the FDA-listed mapping footprint, not sales, inventory, availability, or market share.

💲 Pricing (NADAC)

NADAC is CMS's National Average Drug Acquisition Cost — roughly what pharmacies pay to buy the drug. It is an acquisition benchmark, not your copay.
Per gm · median
$16.2547
Range $16.2547–$16.2547 · middle 50% $16.2547–$16.2547 · 1 NDCs
Latest compatible distributions from the CMS NADAC file · dataset watermark 2026-07-10. Prices vary by package and pharmacy; a distribution is shown instead of one misleading number. Rows the dataset is silent on carry no price. No zero-cost conclusion should be drawn.

🗃️ Sources & Limits

Atlas generation902fddb9-e9c1-4004-bf4c-dba4d51037c7
openFDA export observedJul 14, 2026
RxNorm release07/06/2026
Methodology2026-07-full-catalog-v1
  • A shared RxCUI does not prove interchangeability. Products mapped to the same concept are not thereby equivalent or substitutable — equivalence is a separate, product-level determination.
  • Listing here does not establish approval or coverage. Appearing in this snapshot is a data observation, not an FDA approval status or a payer coverage decision.
  • Missing data never means zero. A silent dataset (no price, no billing code, no utilization) means no observation — not that the real-world value is zero.
  • Counts describe the mapping footprint. Product, package, and labeler counts are the FDA-listed mapping footprint in this snapshot — not sales, inventory, availability, or market share.
This product uses publicly available data from the U.S. National Library of Medicine (NLM), National Institutes of Health, Department of Health and Human Services; NLM is not responsible for the product and does not endorse or recommend this or any other product.

Machine-readable JSON

Reference information about drug-concept identifiers and public regulatory data — not medical advice. Talk to your pharmacist or prescriber about your own medication.