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20 ML fosnetupitant 11.75 MG/ML / palonosetron 0.0125 MG/ML Injection — RxCUI 2374366

Name: 20 ML fosnetupitant 11.75 MG/ML / palonosetron 0.0125 MG/ML Injection (RxCUI 2374366)
Creator: Brian Staiger, PharmD

RxNorm drug concept · Semantic clinical drug

RxCUI 2374366 Semantic clinical drug · SCD ● Current RxNorm concept 3 FDA products 4 package NDCs Snapshot Jul 14, 2026

This page is curated, coded, and maintained by Dr. Brian Staiger, PharmD

Compiled from public NLM RxNorm and FDA (openFDA NDC directory) data sources. Editorial policy

What you’re looking at: the standardized identity of one medicine, as the U.S. drug-data system sees it. Below — every FDA-listed product, package code, price benchmark, and billing code that maps to it.

🗂️ Key Facts

RxCUI2374366

Official name20 ML fosnetupitant 11.75 MG/ML / palonosetron 0.0125 MG/ML Injection

Concept typeSemantic clinical drug (SCD)

RxNorm statusCurrent RxNorm concept

Also known asfosnetupitant 235 MG / palonosetron 0.25 MG per 20 ML Injection; fosnetupitant 235 MG / palonosetron 0.25 MG in 20 ML Injection; fosnetupitant 235 MG (equivalent to fosnetupitant chloride HCl 260 MG) / palonosetron 0.25 MG (equivalent to palonosetron HCl 28 MG) per 20 ML Injection

FDA products mapped3

Package NDCs mapped4

Reported Medicaid activity (SDUD)7,574 prescriptions · 27 state & territory Medicaid programs · latest period Q4 2025

RxNorm release07/06/2026

Snapshot dataJul 14, 2026

📖 Skip the Codes — Read It in Plain English.

Our pharmacist-built guide to Palonosetron Injection: what it is, how it’s used, side effects, and interactions.

📗 Our plain-language guide HelloPharmacist

It's an anti-nausea medicine given through an IV by your healthcare team. It's used to prevent nausea and vomiting that chemotherapy can cause — both the kind that hits within the...
What is palonosetron injection (Posfrea) actually used for?
You'll always receive this in a clinical setting — a hospital, infusion center, or surgical suite. A nurse or other healthcare professional gives it as an IV infusion or injection....
Will I receive this at home, or does it have to be given by a healthcare provider?

📖 Read our full Palonosetron Injection guide →

🕸️ Concept Web — How 20 ML fosnetupitant 11.75 MG/ML / palonosetron 0... Connects

One RxCUI never lives alone. Follow the path from the raw ingredient down to the exact strength-and-form concepts FDA products carry — every stop is a real RxNorm concept with its own identifier. Hover or focus any chip for what it means.

This page's concept 20 ML fosnetupitant 11.75 MG/ML / palonosetron 0.0125 MG/ML Injection RxCUI 2374366 Semantic clinical drug · SCD

Every web starts here: one RxCUI, one fixed meaning in the RxNorm vocabulary.

Ingredients 4

The active substance itself — no strength, form, or brand attached yet.
- Netupitant 1552337 IN
- Palonosetron 70561 IN
- Netupitant / palonosetron 1552342 MIN
- Fosnetupitant 2044417 PIN
Brand names 1

The same medicine's trade names. A brand name alone says nothing about strength or form.
- Akynzeo 1552344 BN
Dose forms 9

The ingredient poured into a form — tablet, solution, cream — still without one fixed strength.
- Netupitant / palonosetron Injection 2044421 SCDF
- Fosnetupitant / palonosetron Injection 2648306 SCDFP
- Netupitant / palonosetron Injectable Product 2044420 SCDG
- Fosnetupitant / palonosetron Injectable Product 2659717 SCDGP
- Netupitant / palonosetron Injection [Akynzeo] 2044424 SBDF
- Fosnetupitant / palonosetron Injection [Akynzeo] 2656493 SBDFP
- Akynzeo Injectable Product 2044425 SBDG
- Injection 1649574 DF
- +1 more in this family
Clinical & branded drugs 4

Ingredient + strength + dose form. These are the concepts real FDA products actually carry.
- Fosnetupitant 11.75 MG/ML 2374364 SCDC
- Palonosetron 0.0125 MG/ML 2374365 SCDC
- 20 ML fosnetupitant 11.75 MG/ML / palonosetron 0.0125 MG/ML Injection [Akynzeo] 2374368 SBD
- Fosnetupitant 11.75 MG/ML / palonosetron 0.0125 MG/ML [Akynzeo] 2374367 SBDC

Showing up to 8 concepts per family — 17 of 18 stored related concepts drawn.

These are official RxNorm vocabulary relationships — how concepts name and organize the same medicine. They do not establish therapeutic equivalence or substitutability: two concepts appearing in one web is never a statement that products can be swapped.

🔀 Generic ⇄ Brand Crosswalk

The same medicine has an unbranded (generic) identity and one or more brand-name identities — each with its own RxCUI. This is a naming relationship in RxNorm, not a statement that any two products are substitutable.

Generic (Clinical) Concepts

Fosnetupitant 11.75 MG/ML SCDC · 2374364
Palonosetron 0.0125 MG/ML SCDC · 2374365
Netupitant / palonosetron Injection SCDF · 2044421
Fosnetupitant / palonosetron Injection SCDFP · 2648306
Netupitant / palonosetron Injectable Product SCDG · 2044420
Fosnetupitant / palonosetron Injectable Product SCDGP · 2659717

Brand-Name Concepts

20 ML fosnetupitant 11.75 MG/ML / palonosetron 0.0125 MG/ML Injection [Akynzeo] SBD · 2374368
Fosnetupitant 11.75 MG/ML / palonosetron 0.0125 MG/ML [Akynzeo] SBDC · 2374367
Netupitant / palonosetron Injection [Akynzeo] SBDF · 2044424
Fosnetupitant / palonosetron Injection [Akynzeo] SBDFP · 2656493
Akynzeo Injectable Product SBDG · 2044425
Akynzeo BN · 1552344

📦 FDA Products & Package NDCs

3 products · 4 package NDCs

4 package NDCs map to RxCUI 2374366 in the current snapshot — up to 50 per page. Each linked NDC opens its full package page.

Package NDC	Package	Brand / generic name	Labeler	Marketing start
69639-0101-01	1 BLISTER PACK in 1 CARTON (69639-101-01) / 1 CAPSULE in 1...	AKYNZEO	Helsinn Therapeutics (U.S.), Inc.	2014-10-13
69639-0101-04	2 BLISTER PACK in 1 CARTON (69639-101-04) / 2 CAPSULE in 1...	AKYNZEO	Helsinn Therapeutics (U.S.), Inc.	2014-10-13
69639-0105-01	1 VIAL in 1 CARTON (69639-105-01) / 20 mL in 1 VIAL	AKYNZEO	Helsinn Therapeutics (U.S.), Inc.	2020-06-15
69639-0106-01	1 VIAL, SINGLE-DOSE in 1 CARTON (69639-106-01) / 20 mL in 1...	AKYNZEO	Helsinn Therapeutics (U.S.), Inc.	2023-08-01

Observed labelers: Helsinn Therapeutics (U.S.), Inc. (4) — this is the FDA-listed mapping footprint, not sales, inventory, availability, or market share.

🧾 Billing Codes (HCPCS)

Medical billing codes (HCPCS "J-codes") that connect to this concept's packages — used mostly when a clinic or hospital bills for a drug it administers. Each code links to its full billing page.

Code	Descriptor	Mapped packages	Sources
J1454	Inj fosnetupitant, palonoset	2	CMS
J8655	Oral netupitant, palonosetro	1	CMS

⚠ A crosswalk is not coverage: an NDC↔HCPCS mapping does not guarantee any payer covers or pays the code. Always verify the current payer policy before billing.

🗃️ Sources & Limits

Atlas generation902fddb9-e9c1-4004-bf4c-dba4d51037c7

openFDA export observedJul 14, 2026

RxNorm release07/06/2026

Methodology2026-07-full-catalog-v1

A shared RxCUI does not prove interchangeability. Products mapped to the same concept are not thereby equivalent or substitutable — equivalence is a separate, product-level determination.
Listing here does not establish approval or coverage. Appearing in this snapshot is a data observation, not an FDA approval status or a payer coverage decision.
Missing data never means zero. A silent dataset (no price, no billing code, no utilization) means no observation — not that the real-world value is zero.
Counts describe the mapping footprint. Product, package, and labeler counts are the FDA-listed mapping footprint in this snapshot — not sales, inventory, availability, or market share.

This product uses publicly available data from the U.S. National Library of Medicine (NLM), National Institutes of Health, Department of Health and Human Services; NLM is not responsible for the product and does not endorse or recommend this or any other product.

Machine-readable JSON

Reference information about drug-concept identifiers and public regulatory data — not medical advice. Talk to your pharmacist or prescriber about your own medication.