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Lidocaine 40 MG/ML / phenylephrine hydrochloride 2.5 MG/ML Rectal Cream — RxCUI 2529640

Name: Lidocaine 40 MG/ML / phenylephrine hydrochloride 2.5 MG/ML Rectal Cream (RxCUI 2529640)
Creator: Brian Staiger, PharmD

RxNorm drug concept · Semantic clinical drug

RxCUI 2529640 Semantic clinical drug · SCD ● Current RxNorm concept 5 FDA products 5 package NDCs Snapshot Jul 14, 2026

This page is curated, coded, and maintained by Dr. Brian Staiger, PharmD

Compiled from public NLM RxNorm and FDA (openFDA NDC directory) data sources. Editorial policy

What you’re looking at: the standardized identity of one medicine, as the U.S. drug-data system sees it. Below — every FDA-listed product, package code, price benchmark, and billing code that maps to it.

🗂️ Key Facts

RxCUI2529640

Official nameLidocaine 40 MG/ML / phenylephrine hydrochloride 2.5 MG/ML Rectal Cream

Concept typeSemantic clinical drug (SCD)

RxNorm statusCurrent RxNorm concept

Also known aslidocaine 4 % / phenylephrine hydrochloride 0.25 % Rectal Cream

FDA products mapped5

Package NDCs mapped5

RxNorm release07/06/2026

Snapshot dataJul 14, 2026

📖 Skip the Codes — Read It in Plain English.

Our pharmacist-built guide to Lidocaine Transdermal Patch: what it is, how it’s used, side effects, and interactions.

📗 Our plain-language guide HelloPharmacist

It relieves nerve pain from post-herpetic neuralgia, the lingering pain that can follow shingles. It is used in adults. It numbs the pain signals in the skin under the patch.
Usually up to 12 hours in a 24-hour period, then 12 hours off. Put it on intact skin over the most painful spot. Do not use more patches than prescribed.
No. Heat can increase how much lidocaine gets absorbed. With Ztlido, you can apply a patch after brief heat, but never put a heating pad or electric blanket directly on it.
For Ztlido, light exercise and short water exposure, like a 10-minute shower, are okay. Gently pat it dry rather than rubbing. If the edges lift, press them down.

📖 Read our full Lidocaine Transdermal Patch guide →

🕸️ Concept Web — How Lidocaine 40 MG/ML / phenylephrine hydrochloride... Connects

One RxCUI never lives alone. Follow the path from the raw ingredient down to the exact strength-and-form concepts FDA products carry — every stop is a real RxNorm concept with its own identifier. Hover or focus any chip for what it means.

This page's concept Lidocaine 40 MG/ML / phenylephrine hydrochloride 2.5 MG/ML Rectal Cream RxCUI 2529640 Semantic clinical drug · SCD

Every web starts here: one RxCUI, one fixed meaning in the RxNorm vocabulary.

Ingredients 4

The active substance itself — no strength, form, or brand attached yet.
- Lidocaine 6387 IN
- Phenylephrine 8163 IN
- Lidocaine / phenylephrine 226976 MIN
- Phenylephrine hydrochloride 8164 PIN
Dose forms 6

The ingredient poured into a form — tablet, solution, cream — still without one fixed strength.
- Lidocaine / phenylephrine Rectal Cream 1314135 SCDF
- Lidocaine / phenylephrine hydrochloride Rectal Cream 2648665 SCDFP
- Lidocaine / phenylephrine Rectal Product 1314134 SCDG
- Lidocaine / phenylephrine hydrochloride Rectal Product 2662038 SCDGP
- Rectal Cream 316975 DF
- Rectal Product 1151127 DFG
Clinical & branded drugs 2

Ingredient + strength + dose form. These are the concepts real FDA products actually carry.
- Lidocaine 40 MG/ML 330627 SCDC
- Phenylephrine hydrochloride 2.5 MG/ML 997282 SCDC

Showing up to 8 concepts per family — 12 of 12 stored related concepts drawn.

These are official RxNorm vocabulary relationships — how concepts name and organize the same medicine. They do not establish therapeutic equivalence or substitutability: two concepts appearing in one web is never a statement that products can be swapped.

🔀 Generic ⇄ Brand Crosswalk

The same medicine has an unbranded (generic) identity and one or more brand-name identities — each with its own RxCUI. This is a naming relationship in RxNorm, not a statement that any two products are substitutable.

Generic (Clinical) Concepts

Lidocaine 40 MG/ML SCDC · 330627
Phenylephrine hydrochloride 2.5 MG/ML SCDC · 997282
Lidocaine / phenylephrine Rectal Cream SCDF · 1314135
Lidocaine / phenylephrine hydrochloride Rectal Cream SCDFP · 2648665
Lidocaine / phenylephrine Rectal Product SCDG · 1314134
Lidocaine / phenylephrine hydrochloride Rectal Product SCDGP · 2662038

📦 FDA Products & Package NDCs

5 products · 5 package NDCs

5 package NDCs map to RxCUI 2529640 in the current snapshot — up to 50 per page. Each linked NDC opens its full package page.

Package NDC	Package	Brand / generic name	Labeler	Marketing start
85248-0031-01	20 g in 1 TUBE (85248-031-01)	Alveora HEMORRHOID MASTER	Jiangxi Yudexi Pharmaceutical Co., LTD	2026-01-30
85248-0044-01	42.5 g in 1 BOTTLE (85248-044-01)	Natucure HEMORRHOID	Jiangxi Yudexi Pharmaceutical Co., LTD	2026-02-03
85248-0128-01	20 g in 1 TUBE (85248-128-01)	NICOVITO HEMORRHOID MASTER	Jiangxi Yudexi Pharmaceutical Co., LTD	2026-02-09
85248-0155-01	20 g in 1 TUBE (85248-155-01)	SERYNTH HEMORRHOID	Jiangxi Yudexi Pharmaceutical Co., LTD	2026-03-07
85248-0162-01	20 g in 1 TUBE (85248-162-01)	Dr.Harry COMFORT ZONE Cream	Jiangxi Yudexi Pharmaceutical Co., LTD	2026-03-17

Observed labelers: Jiangxi Yudexi Pharmaceutical Co., LTD (5) — this is the FDA-listed mapping footprint, not sales, inventory, availability, or market share.

🗃️ Sources & Limits

Atlas generation902fddb9-e9c1-4004-bf4c-dba4d51037c7

openFDA export observedJul 14, 2026

RxNorm release07/06/2026

Methodology2026-07-full-catalog-v1

A shared RxCUI does not prove interchangeability. Products mapped to the same concept are not thereby equivalent or substitutable — equivalence is a separate, product-level determination.
Listing here does not establish approval or coverage. Appearing in this snapshot is a data observation, not an FDA approval status or a payer coverage decision.
Missing data never means zero. A silent dataset (no price, no billing code, no utilization) means no observation — not that the real-world value is zero.
Counts describe the mapping footprint. Product, package, and labeler counts are the FDA-listed mapping footprint in this snapshot — not sales, inventory, availability, or market share.

This product uses publicly available data from the U.S. National Library of Medicine (NLM), National Institutes of Health, Department of Health and Human Services; NLM is not responsible for the product and does not endorse or recommend this or any other product.

Machine-readable JSON

Reference information about drug-concept identifiers and public regulatory data — not medical advice. Talk to your pharmacist or prescriber about your own medication.