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Acetaminophen 325 MG / dextromethorphan hydrobromide 10 MG / phenylephrine hydrochloride 5... — RxCUI 2549037

RxNorm drug concept · Semantic clinical drug
RxCUI 2549037 Semantic clinical drug · SCD ● Current RxNorm concept 7 FDA products 12 package NDCs Snapshot Jul 14, 2026

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Compiled from public NLM RxNorm and FDA (openFDA NDC directory) data sources. Editorial policy

What you’re looking at: the standardized identity of one medicine, as the U.S. drug-data system sees it. Below — every FDA-listed product, package code, price benchmark, and billing code that maps to it.

🗂️ Key Facts

RxCUI2549037
Official nameAcetaminophen 325 MG / dextromethorphan hydrobromide 10 MG / phenylephrine hydrochloride 5 MG / triprolidine hydrochloride 1.25 MG Oral Tablet
Concept typeSemantic clinical drug (SCD)
RxNorm statusCurrent RxNorm concept
Also known asAPAP 325 MG / dextromethorphan hydrobromide 10 MG / phenylephrine hydrochloride 5 MG / triprolidine hydrochloride 1.25 MG Oral Tablet; acetaminophen 325 MG / dextromethorphan HBr 10 MG / phenylephrine HCl 5 MG / triprolidine HCl 1.25 MG Oral Tablet
FDA products mapped7
Package NDCs mapped12
RxNorm release07/06/2026
Snapshot dataJul 14, 2026

📖 Skip the Codes — Read It in Plain English.

Our pharmacist-built guide to Phenylephrine: what it is, how it’s used, side effects, and interactions.

📗 Our plain-language guide HelloPharmacist
  • Yes, it's the same active ingredient, but used in very different ways depending on the form. The nasal spray delivers a tiny amount directly to the nasal lining to temporarily shri...
  • I see phenylephrine in nasal sprays at the pharmacy AND as an IV drug in the hospital — is it really the same medication?
  • You should check with your doctor first. Phenylephrine constricts blood vessels, which can raise blood pressure and put extra strain on the heart — even from a nasal spray. If you...
  • Can I use the nasal spray if I have high blood pressure or heart disease?
📖 Read our full Phenylephrine guide →

🕸️ Concept Web — How Acetaminophen 325 MG / dextromethorphan hydrobro... Connects

One RxCUI never lives alone. Follow the path from the raw ingredient down to the exact strength-and-form concepts FDA products carry — every stop is a real RxNorm concept with its own identifier. Hover or focus any chip for what it means.
This page's concept Acetaminophen 325 MG / dextromethorphan hydrobromide 10 MG / phenylephrine hydrochloride 5 MG / triprolidine hydrochloride 1.25 MG Oral Tablet RxCUI 2549037

Every web starts here: one RxCUI, one fixed meaning in the RxNorm vocabulary.

  1. Ingredients 8

    The active substance itself — no strength, form, or brand attached yet.

    • Acetaminophen 161
    • Dextromethorphan 3289
    • Phenylephrine 8163
    • Triprolidine 10849
    • Acetaminophen / dextromethorphan / phenylephrine / triprolidine 2173661
    • Dextromethorphan hydrobromide 102490
    • Phenylephrine hydrochloride 8164
    • Triprolidine hydrochloride 71534
  2. Dose forms 9

    The ingredient poured into a form — tablet, solution, cream — still without one fixed strength.

    • Acetaminophen / dextromethorphan / phenylephrine / triprolidine Oral Tablet 2549036
    • Acetaminophen / dextromethorphan hydrobromide / phenylephrine hydrochloride / triprolidine hydrochloride Oral Tablet 2648212
    • Acetaminophen / dextromethorphan / phenylephrine / triprolidine Oral Product 2173659
    • Acetaminophen / dextromethorphan / phenylephrine / triprolidine Pill 2549035
    • Acetaminophen / dextromethorphan hydrobromide / phenylephrine hydrochloride / triprolidine hydrochloride Oral Product 2661608
    • Acetaminophen / dextromethorphan hydrobromide / phenylephrine hydrochloride / triprolidine hydrochloride Pill 2661137
    • Oral Tablet 317541
    • Oral Product 1151131
    • +1 more in this family
  3. Clinical & branded drugs 4

    Ingredient + strength + dose form. These are the concepts real FDA products actually carry.

    • Acetaminophen 325 MG 315263
    • Dextromethorphan hydrobromide 10 MG 1014455
    • Phenylephrine hydrochloride 5 MG 1020198
    • Triprolidine hydrochloride 1.25 MG 1099642
  4. Packs 1

    Fixed collections of drugs packaged and sold together, like dose packs.

Showing up to 8 concepts per family — 21 of 22 stored related concepts drawn.
These are official RxNorm vocabulary relationships — how concepts name and organize the same medicine. They do not establish therapeutic equivalence or substitutability: two concepts appearing in one web is never a statement that products can be swapped.

🔀 Generic ⇄ Brand Crosswalk

The same medicine has an unbranded (generic) identity and one or more brand-name identities — each with its own RxCUI. This is a naming relationship in RxNorm, not a statement that any two products are substitutable.

Generic (Clinical) Concepts

📦 FDA Products & Package NDCs

7 products · 12 package NDCs
12 package NDCs map to RxCUI 2549037 in the current snapshot — up to 50 per page. Each linked NDC opens its full package page.
Package NDC Package Brand / generic name Labeler Marketing start
00363-9617-64 4 BLISTER PACK in 1 CARTON (0363-9617-64) / 1 KIT in 1 BLIS... Mucus DM Fast Max Day Cold and Flu and Night Cold and Flu WALGREENS 2024-12-23
11673-0343-64 4 BLISTER PACK in 1 CARTON (11673-343-64) / 1 KIT in 1 BLIS... Day Cold and Flu and Night Severe Cold and Flu TARGET CORPORATION 2024-05-01
49483-0726-64 4 BLISTER PACK in 1 CARTON (49483-726-64) / 1 KIT in 1 BLIS... Maximum strength Day cold and flu and Night severe cold and flu TIME CAP LABORATORIES,INC 2023-09-21
72854-0234-02 2 TABLET, COATED in 1 PACKET (72854-234-02) Mucinex Nightshift Severe Cold and Flu Maximum Strength Reckitt Benckiser LLC 2021-07-01
72854-0234-20 2 BLISTER PACK in 1 CARTON (72854-234-20) / 10 TABLET, COAT... Mucinex Nightshift Severe Cold and Flu Maximum Strength Reckitt Benckiser LLC 2021-07-01
72854-0240-20 2 BLISTER PACK in 1 CARTON (72854-240-20) / 10 TABLET, COAT... Mucinex Nightshift Sinus Maximum Strength Reckitt Benckiser LLC 2021-07-01
72854-0241-10 1 KIT in 1 CARTON (72854-241-10) / 1 KIT in 1 KIT * 6 TABL... Mucinex Fast-Max Day Cold and Flu and Mucinex Nightshift Night Severe Cold and Flu Maximum Strength Reckitt Benckiser LLC 2021-07-01
72854-0241-20 2 KIT in 1 CARTON (72854-241-20) / 1 KIT in 1 KIT * 6 TABL... Mucinex Fast-Max Day Cold and Flu and Mucinex Nightshift Night Severe Cold and Flu Maximum Strength Reckitt Benckiser LLC 2021-07-01
72854-0241-40 4 KIT in 1 CARTON (72854-241-40) / 1 KIT in 1 KIT * 6 TABL... Mucinex Fast-Max Day Cold and Flu and Mucinex Nightshift Night Severe Cold and Flu Maximum Strength Reckitt Benckiser LLC 2021-07-01
72854-0243-10 1 KIT in 1 CARTON (72854-243-10) / 1 KIT in 1 KIT * 6 TABL... Mucinex Sinus-Max Day Pressure, Pain and Cough and Mucinex Nightshift Night Sinus Maximum Strength Reckitt Benckiser LLC 2021-07-01
72854-0243-20 2 KIT in 1 CARTON (72854-243-20) / 1 KIT in 1 KIT * 6 TABL... Mucinex Sinus-Max Day Pressure, Pain and Cough and Mucinex Nightshift Night Sinus Maximum Strength Reckitt Benckiser LLC 2021-07-01
72854-0243-40 4 KIT in 1 CARTON (72854-243-40) / 1 KIT in 1 KIT * 6 TABL... Mucinex Sinus-Max Day Pressure, Pain and Cough and Mucinex Nightshift Night Sinus Maximum Strength Reckitt Benckiser LLC 2021-07-01
Observed labelers: Reckitt Benckiser LLC (9) · TARGET CORPORATION (1) · TIME CAP LABORATORIES,INC (1) · WALGREENS (1) — this is the FDA-listed mapping footprint, not sales, inventory, availability, or market share.

🗃️ Sources & Limits

Atlas generation902fddb9-e9c1-4004-bf4c-dba4d51037c7
openFDA export observedJul 14, 2026
RxNorm release07/06/2026
Methodology2026-07-full-catalog-v1
  • A shared RxCUI does not prove interchangeability. Products mapped to the same concept are not thereby equivalent or substitutable — equivalence is a separate, product-level determination.
  • Listing here does not establish approval or coverage. Appearing in this snapshot is a data observation, not an FDA approval status or a payer coverage decision.
  • Missing data never means zero. A silent dataset (no price, no billing code, no utilization) means no observation — not that the real-world value is zero.
  • Counts describe the mapping footprint. Product, package, and labeler counts are the FDA-listed mapping footprint in this snapshot — not sales, inventory, availability, or market share.
This product uses publicly available data from the U.S. National Library of Medicine (NLM), National Institutes of Health, Department of Health and Human Services; NLM is not responsible for the product and does not endorse or recommend this or any other product.

Machine-readable JSON

Reference information about drug-concept identifiers and public regulatory data — not medical advice. Talk to your pharmacist or prescriber about your own medication.