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Dextromethorphan hydrobromide 0.667 MG/ML / guaifenesin 6.667 MG/ML / phenylephrine hydroc... — RxCUI 2566816

Name: Dextromethorphan hydrobromide 0.667 MG/ML / guaifenesin 6.667 MG/ML / phenylephrine h… (RxCUI 2566816)
Creator: Brian Staiger, PharmD

RxNorm drug concept · Semantic clinical drug

RxCUI 2566816 Semantic clinical drug · SCD ● Current RxNorm concept 5 FDA products 7 package NDCs Snapshot Jul 14, 2026

This page is curated, coded, and maintained by Dr. Brian Staiger, PharmD

Compiled from public NLM RxNorm and FDA (openFDA NDC directory) data sources. Editorial policy

What you’re looking at: the standardized identity of one medicine, as the U.S. drug-data system sees it. Below — every FDA-listed product, package code, price benchmark, and billing code that maps to it.

🗂️ Key Facts

RxCUI2566816

Official nameDextromethorphan hydrobromide 0.667 MG/ML / guaifenesin 6.667 MG/ML / phenylephrine hydrochloride 0.333 MG/ML Oral Solution

Concept typeSemantic clinical drug (SCD)

RxNorm statusCurrent RxNorm concept

Also known asdextromethorphan hydrobromide 10 MG / guaifenesin 100 MG / phenylephrine hydrochloride 5 MG per 15 ML Oral Solution; dextromethorphan HBr 10 MG / guaiFENesin 100 MG / phenylephrine HCl 5 MG in 15 mL Oral Solution

FDA products mapped5

Package NDCs mapped7

RxNorm release07/06/2026

Snapshot dataJul 14, 2026

📖 Skip the Codes — Read It in Plain English.

Our pharmacist-built guide to Phenylephrine: what it is, how it’s used, side effects, and interactions.

📗 Our plain-language guide HelloPharmacist

Yes, it's the same active ingredient, but used in very different ways depending on the form. The nasal spray delivers a tiny amount directly to the nasal lining to temporarily shri...
I see phenylephrine in nasal sprays at the pharmacy AND as an IV drug in the hospital — is it really the same medication?
You should check with your doctor first. Phenylephrine constricts blood vessels, which can raise blood pressure and put extra strain on the heart — even from a nasal spray. If you...
Can I use the nasal spray if I have high blood pressure or heart disease?

📖 Read our full Phenylephrine guide →

🕸️ Concept Web — How Dextromethorphan hydrobromide 0.667 MG/ML / guai... Connects

One RxCUI never lives alone. Follow the path from the raw ingredient down to the exact strength-and-form concepts FDA products carry — every stop is a real RxNorm concept with its own identifier. Hover or focus any chip for what it means.

This page's concept Dextromethorphan hydrobromide 0.667 MG/ML / guaifenesin 6.667 MG/ML / phenylephrine hydrochloride 0.333 MG/ML Oral Solution RxCUI 2566816 Semantic clinical drug · SCD

Every web starts here: one RxCUI, one fixed meaning in the RxNorm vocabulary.

Ingredients 6

The active substance itself — no strength, form, or brand attached yet.
- Dextromethorphan 3289 IN
- Guaifenesin 5032 IN
- Phenylephrine 8163 IN
- Dextromethorphan / guaifenesin / phenylephrine 214494 MIN
- Dextromethorphan hydrobromide 102490 PIN
- Phenylephrine hydrochloride 8164 PIN
Dose forms 9

The ingredient poured into a form — tablet, solution, cream — still without one fixed strength.
- Dextromethorphan / guaifenesin / phenylephrine Oral Solution 375427 SCDF
- Dextromethorphan hydrobromide / guaifenesin / phenylephrine hydrochloride Oral Solution 2645876 SCDFP
- Dextromethorphan / guaifenesin / phenylephrine Oral Liquid Product 1154857 SCDG
- Dextromethorphan / guaifenesin / phenylephrine Oral Product 1154858 SCDG
- Dextromethorphan hydrobromide / guaifenesin / phenylephrine hydrochloride Oral Liquid Product 2663136 SCDGP
- Dextromethorphan hydrobromide / guaifenesin / phenylephrine hydrochloride Oral Product 2663549 SCDGP
- Oral Solution 316968 DF
- Oral Liquid Product 1151137 DFG
- +1 more in this family
Clinical & branded drugs 3

Ingredient + strength + dose form. These are the concepts real FDA products actually carry.
- Dextromethorphan hydrobromide 0.667 MG/ML 1014004 SCDC
- Guaifenesin 6.667 MG/ML 2566815 SCDC
- Phenylephrine hydrochloride 0.333 MG/ML 1039296 SCDC
Packs 1

Fixed collections of drugs packaged and sold together, like dose packs.
- {1 (chlorpheniramine maleate 0.133 MG/ML / dextromethorphan hydrobromide 1 MG/ML Oral Solution) / 1 (dextromethorphan hydrobromide 0.667 MG/ML / guaifenesin 6.667 MG/ML / phenylephrine hydrochloride 0.333 MG/ML Oral Solution) } Pack 2644878 GPCK

Showing up to 8 concepts per family — 18 of 19 stored related concepts drawn.

These are official RxNorm vocabulary relationships — how concepts name and organize the same medicine. They do not establish therapeutic equivalence or substitutability: two concepts appearing in one web is never a statement that products can be swapped.

🔀 Generic ⇄ Brand Crosswalk

The same medicine has an unbranded (generic) identity and one or more brand-name identities — each with its own RxCUI. This is a naming relationship in RxNorm, not a statement that any two products are substitutable.

Generic (Clinical) Concepts

{1 (chlorpheniramine maleate 0.133 MG/ML / dextromethorphan hydrobromide 1 MG/ML Oral Solution) / 1 (dextromethorphan hydrobromide 0.667 MG/ML / guaifenesin 6.667 MG/ML / phenylephrine hydrochloride 0.333 MG/ML Oral Solution) } Pack GPCK · 2644878
Dextromethorphan hydrobromide 0.667 MG/ML SCDC · 1014004
Guaifenesin 6.667 MG/ML SCDC · 2566815
Phenylephrine hydrochloride 0.333 MG/ML SCDC · 1039296
Dextromethorphan / guaifenesin / phenylephrine Oral Solution SCDF · 375427
Dextromethorphan hydrobromide / guaifenesin / phenylephrine hydrochloride Oral Solution SCDFP · 2645876
Dextromethorphan / guaifenesin / phenylephrine Oral Liquid Product SCDG · 1154857
Dextromethorphan / guaifenesin / phenylephrine Oral Product SCDG · 1154858
Dextromethorphan hydrobromide / guaifenesin / phenylephrine hydrochloride Oral Liquid Product SCDGP · 2663136
Dextromethorphan hydrobromide / guaifenesin / phenylephrine hydrochloride Oral Product SCDGP · 2663549

📦 FDA Products & Package NDCs

5 products · 7 package NDCs

7 package NDCs map to RxCUI 2566816 in the current snapshot — up to 50 per page. Each linked NDC opens its full package page.

Package NDC	Package	Brand / generic name	Labeler	Marketing start
00363-6238-08	236 mL in 1 BOTTLE, PLASTIC (0363-6238-08)	Walgreen Daytimel Kids Cold Cough plus Mucus	WALGREENS CO.	2023-03-01
69423-0778-08	236 mL in 1 BOTTLE, PLASTIC (69423-778-08)	Vicks DayQuil Kids BERRY COLD and COUGH plus MUCUS	The Procter & Gamble Manufacturing Company	2023-06-06
69423-0778-16	2 BOTTLE, PLASTIC in 1 CELLO PACK (69423-778-16) / 236 mL i...	Vicks DayQuil Kids BERRY COLD and COUGH plus MUCUS	The Procter & Gamble Manufacturing Company	2026-01-20
69423-0780-16	1 KIT in 1 PACKAGE (69423-780-16) * 236 mL in 1 BOTTLE, PL...	Vicks DayQuil NyQuil BERRY Kids COLD and COUGH plus	The Procter & Gamble Manufacturing Company	2023-06-06
69423-0780-24	1 KIT in 1 PACKAGE (69423-780-24) * 236 mL in 1 BOTTLE, PL...	Vicks DayQuil NyQuil BERRY Kids COLD and COUGH plus	The Procter & Gamble Manufacturing Company	2023-06-06
69423-0946-08	236 mL in 1 BOTTLE, PLASTIC (69423-946-08)	Vicks DayQuil Kids Cold Cough plus Mucus	The Procter & Gamble Manufacturing Company	2021-07-08
69423-0993-16	1 KIT in 1 PACKAGE (69423-993-16) * 236 mL in 1 BOTTLE, PL...	Vicks DayQuil Kids Honey and Vicks NyQuil Kids Honey COLD and COUGH plus	The Procter & Gamble Manufacturing Company	2022-07-12

Observed labelers: The Procter & Gamble Manufacturing Company (6) · WALGREENS CO. (1) — this is the FDA-listed mapping footprint, not sales, inventory, availability, or market share.

🗃️ Sources & Limits

Atlas generation902fddb9-e9c1-4004-bf4c-dba4d51037c7

openFDA export observedJul 14, 2026

RxNorm release07/06/2026

Methodology2026-07-full-catalog-v1

A shared RxCUI does not prove interchangeability. Products mapped to the same concept are not thereby equivalent or substitutable — equivalence is a separate, product-level determination.
Listing here does not establish approval or coverage. Appearing in this snapshot is a data observation, not an FDA approval status or a payer coverage decision.
Missing data never means zero. A silent dataset (no price, no billing code, no utilization) means no observation — not that the real-world value is zero.
Counts describe the mapping footprint. Product, package, and labeler counts are the FDA-listed mapping footprint in this snapshot — not sales, inventory, availability, or market share.

This product uses publicly available data from the U.S. National Library of Medicine (NLM), National Institutes of Health, Department of Health and Human Services; NLM is not responsible for the product and does not endorse or recommend this or any other product.

Machine-readable JSON

Reference information about drug-concept identifiers and public regulatory data — not medical advice. Talk to your pharmacist or prescriber about your own medication.