1250 MG estradiol 0.001 MG/MG Topical Gel — RxCUI 2619685
RxNorm drug concept · Semantic clinical drug
RxCUI 2619685
Semantic clinical drug · SCD
● Current RxNorm concept 40 FDA products
45 package NDCs
Snapshot Jul 14, 2026
What you’re looking at: the standardized identity of one medicine, as the U.S. drug-data system sees it. Below — every FDA-listed product, package code, price benchmark, and billing code that maps to it.
🗂️ Key Facts
RxCUI2619685
Official name1250 MG estradiol 0.001 MG/MG Topical Gel
Concept typeSemantic clinical drug (SCD)
RxNorm statusCurrent RxNorm concept
Also known asestradiol 0.1 % Transdermal Gel, 1.25 GM; estradiol 0.1 % (1.25MG / 1.25GM) Transdermal Gel
FDA products mapped40
Package NDCs mapped45
Reported Medicaid activity (SDUD)7,413 prescriptions · 24 state & territory Medicaid programs · latest period Q4 2025
RxNorm release07/06/2026
Snapshot dataJul 14, 2026
📖 Skip the Codes — Read It in Plain English.
Our pharmacist-built guide to Estradiol Topical: what it is, how it’s used, side effects, and interactions.
📗 Our plain-language guide HelloPharmacist
- It's designed to ease the moderate to severe hot flashes and night sweats that come with menopause. When estrogen levels drop after menopause, your body's hormonal signals go a bit...
- What exactly is this medication supposed to do for me?
- Apply it to your upper thigh — alternating right and left sides each day — and spread it over an area roughly the size of two palm prints. Let it dry completely before getting dres...
- How do I use the gel correctly so it actually works?
🕸️ Concept Web — How 1250 MG estradiol 0.001 MG/MG Topical Gel Connects
One RxCUI never lives alone. Follow the path from the raw ingredient down to the exact strength-and-form concepts FDA products carry — every stop is a real RxNorm concept with its own identifier. Hover or focus any chip for what it means.
This page's concept
1250 MG estradiol 0.001 MG/MG Topical Gel
RxCUI 2619685 Semantic clinical drug · SCD
Every web starts here: one RxCUI, one fixed meaning in the RxNorm vocabulary.
-
Ingredients 1
The active substance itself — no strength, form, or brand attached yet.
-
Estradiol
4083IN
-
Estradiol
-
Brand names 1
The same medicine's trade names. A brand name alone says nothing about strength or form.
-
Divigel
722259BN
-
Divigel
-
Dose forms 6
The ingredient poured into a form — tablet, solution, cream — still without one fixed strength.
-
Estradiol Topical Gel
379699SCDF -
Estradiol Topical Product
1165762SCDG -
Estradiol Topical Gel [Divigel]
722261SBDF -
Divigel Topical Product
1173164SBDG -
Topical Gel
346286DF -
Topical Product
1151122DFG
-
Estradiol Topical Gel
-
Clinical & branded drugs 3
Ingredient + strength + dose form. These are the concepts real FDA products actually carry.
-
Estradiol 0.001 MG/MG
379701SCDC -
1250 MG estradiol 0.001 MG/MG Topical Gel [Divigel]
2619686SBD -
Estradiol 0.001 MG/MG [Divigel]
723525SBDC
-
Estradiol 0.001 MG/MG
Showing up to 8 concepts per family — 11 of 11 stored related concepts drawn.
These are official RxNorm vocabulary relationships — how concepts name and organize the same medicine. They do not establish therapeutic equivalence or substitutability: two concepts appearing in one web is never a statement that products can be swapped.
🔀 Generic ⇄ Brand Crosswalk
The same medicine has an unbranded (generic) identity and one or more brand-name identities — each with its own RxCUI. This is a naming relationship in RxNorm, not a statement that any two products are substitutable.
Generic (Clinical) Concepts
-
Estradiol 0.001 MG/MG
SCDC · 379701 -
Estradiol Topical Gel
SCDF · 379699 -
Estradiol Topical Product
SCDG · 1165762
Brand-Name Concepts
-
1250 MG estradiol 0.001 MG/MG Topical Gel [Divigel]
SBD · 2619686 -
Estradiol 0.001 MG/MG [Divigel]
SBDC · 723525 -
Estradiol Topical Gel [Divigel]
SBDF · 722261 -
Divigel Topical Product
SBDG · 1173164 -
Divigel
BN · 722259
📦 FDA Products & Package NDCs
40 products · 45 package NDCs
45 package NDCs map to RxCUI 2619685 in the current snapshot — up to 50 per page. Each linked NDC opens its full package page.
| Package NDC | Package | Brand / generic name | Labeler | Marketing start |
|---|---|---|---|---|
| 13811-0090-32 | 30 PACKET in 1 CARTON (13811-090-32) / .25 g in 1 PACKET | Estradiol | Trigen Laboratories, LLC | 2022-10-10 |
| 13811-0091-32 | 30 PACKET in 1 CARTON (13811-091-32) / .5 g in 1 PACKET | Estradiol | Trigen Laboratories, LLC | 2022-10-10 |
| 13811-0092-32 | 30 PACKET in 1 CARTON (13811-092-32) / .75 g in 1 PACKET | Estradiol | Trigen Laboratories, LLC | 2022-10-10 |
| 13811-0093-32 | 30 PACKET in 1 CARTON (13811-093-32) / 1 g in 1 PACKET | Estradiol | Trigen Laboratories, LLC | 2022-10-10 |
| 13811-0094-32 | 30 PACKET in 1 CARTON (13811-094-32) / 1.25 g in 1 PACKET | Estradiol | Trigen Laboratories, LLC | 2022-10-10 |
| 21922-0086-52 | 30 PACKET in 1 CARTON (21922-086-52) / .25 g in 1 PACKET | Estradiol Gel | Encube Ethicals, Inc. | 2025-03-10 |
| 21922-0087-52 | 30 PACKET in 1 CARTON (21922-087-52) / .5 g in 1 PACKET | Estradiol Gel | Encube Ethicals, Inc. | 2025-03-10 |
| 21922-0088-52 | 30 PACKET in 1 CARTON (21922-088-52) / .75 g in 1 PACKET | Estradiol Gel | Encube Ethicals, Inc. | 2025-03-10 |
| 21922-0089-52 | 30 PACKET in 1 CARTON (21922-089-52) / 1 g in 1 PACKET | Estradiol Gel | Encube Ethicals, Inc. | 2025-03-10 |
| 21922-0090-52 | 30 PACKET in 1 CARTON (21922-090-52) / 1.25 g in 1 PACKET | Estradiol Gel | Encube Ethicals, Inc. | 2025-03-10 |
| 45802-0134-30 | 30 PACKET in 1 CARTON (45802-134-30) / .25 g in 1 PACKET | ESTRADIOL | Padagis Israel Pharmaceuticals Ltd | 2023-12-07 |
| 45802-0202-30 | 30 PACKET in 1 CARTON (45802-202-30) / .5 g in 1 PACKET | ESTRADIOL | Padagis Israel Pharmaceuticals Ltd | 2023-12-07 |
| 45802-0310-30 | 30 PACKET in 1 CARTON (45802-310-30) / .75 g in 1 PACKET | ESTRADIOL | Padagis Israel Pharmaceuticals Ltd | 2023-12-07 |
| 45802-0452-30 | 30 PACKET in 1 CARTON (45802-452-30) / 1 g in 1 PACKET | ESTRADIOL | Padagis Israel Pharmaceuticals Ltd | 2023-12-07 |
| 45802-0573-30 | 30 PACKET in 1 CARTON (45802-573-30) / 1.25 g in 1 PACKET | ESTRADIOL | Padagis Israel Pharmaceuticals Ltd | 2023-12-07 |
| 68025-0065-07 | 7 PACKET in 1 CARTON (68025-065-07) / .25 g in 1 PACKET | DIVIGEL | Vertical Pharmaceuticals, LLC | 2014-10-27 |
| 68025-0065-30 | 30 PACKET in 1 CARTON (68025-065-30) / .25 g in 1 PACKET | DIVIGEL | Vertical Pharmaceuticals, LLC | 2014-10-27 |
| 68025-0066-07 | 7 PACKET in 1 CARTON (68025-066-07) / .5 g in 1 PACKET | DIVIGEL | Vertical Pharmaceuticals, LLC | 2014-10-27 |
| 68025-0066-30 | 30 PACKET in 1 CARTON (68025-066-30) / .5 g in 1 PACKET | DIVIGEL | Vertical Pharmaceuticals, LLC | 2014-10-27 |
| 68025-0067-07 | 7 PACKET in 1 CARTON (68025-067-07) / 1 g in 1 PACKET | DIVIGEL | Vertical Pharmaceuticals, LLC | 2014-10-27 |
| 68025-0067-30 | 30 PACKET in 1 CARTON (68025-067-30) / 1 g in 1 PACKET | DIVIGEL | Vertical Pharmaceuticals, LLC | 2014-10-27 |
| 68025-0083-07 | 7 PACKET in 1 CARTON (68025-083-07) / .75 g in 1 PACKET | DIVIGEL | Vertical Pharmaceuticals, LLC | 2019-01-18 |
| 68025-0083-30 | 30 PACKET in 1 CARTON (68025-083-30) / .75 g in 1 PACKET | DIVIGEL | Vertical Pharmaceuticals, LLC | 2019-01-18 |
| 68025-0086-07 | 7 PACKET in 1 CARTON (68025-086-07) / 1.25 g in 1 PACKET | DIVIGEL | Vertical Pharmaceuticals, LLC | 2019-12-17 |
| 68025-0086-30 | 30 PACKET in 1 CARTON (68025-086-30) / 1.25 g in 1 PACKET | DIVIGEL | Vertical Pharmaceuticals, LLC | 2019-12-17 |
| 69238-2448-03 | 30 PACKET in 1 CARTON (69238-2448-3) / 1.25 g in 1 PACKET (... | Estradiol | Amneal Pharmaceuticals NY LLC | 2024-07-15 |
| 69238-2449-03 | 30 PACKET in 1 CARTON (69238-2449-3) / 1 g in 1 PACKET (692... | Estradiol | Amneal Pharmaceuticals NY LLC | 2024-07-15 |
| 69238-2450-03 | 30 PACKET in 1 CARTON (69238-2450-3) / .75 g in 1 PACKET (6... | Estradiol | Amneal Pharmaceuticals NY LLC | 2024-07-15 |
| 69238-2451-03 | 30 PACKET in 1 CARTON (69238-2451-3) / .5 g in 1 PACKET (69... | Estradiol | Amneal Pharmaceuticals NY LLC | 2024-07-15 |
| 69238-2452-03 | 30 PACKET in 1 CARTON (69238-2452-3) / .25 g in 1 PACKET (6... | Estradiol | Amneal Pharmaceuticals NY LLC | 2024-07-15 |
| 70700-0143-35 | 30 PACKET in 1 CARTON (70700-143-35) / .25 g in 1 PACKET | Estradiol | Xiromed, LLC | 2022-10-01 |
| 70700-0144-35 | 30 PACKET in 1 CARTON (70700-144-35) / .5 g in 1 PACKET | Estradiol | Xiromed, LLC | 2022-10-01 |
| 70700-0145-35 | 30 PACKET in 1 CARTON (70700-145-35) / 1 g in 1 PACKET | Estradiol | Xiromed, LLC | 2022-10-01 |
| 70700-0194-35 | 30 PACKET in 1 CARTON (70700-194-35) / .75 g in 1 PACKET | Estradiol | Xiromed, LLC | 2022-10-01 |
| 70700-0195-35 | 30 PACKET in 1 CARTON (70700-195-35) / 1.25 g in 1 PACKET | Estradiol | Xiromed, LLC | 2022-10-01 |
| 70954-0530-20 | 30 PACKET in 1 CARTON (70954-530-20) / .5 g in 1 PACKET (70... | Estradiol | ANI Pharmaceuticals, Inc. | 2023-08-30 |
| 70954-0531-20 | 30 PACKET in 1 CARTON (70954-531-20) / .25 g in 1 PACKET (7... | Estradiol | ANI Pharmaceuticals, Inc. | 2023-08-24 |
| 70954-0532-20 | 30 PACKET in 1 CARTON (70954-532-20) / .75 g in 1 PACKET (7... | Estradiol | ANI Pharmaceuticals, Inc. | 2023-08-24 |
| 70954-0533-20 | 30 PACKET in 1 CARTON (70954-533-20) / 1 g in 1 PACKET (709... | Estradiol | ANI Pharmaceuticals, Inc. | 2023-08-24 |
| 70954-0534-20 | 30 PACKET in 1 CARTON (70954-534-20) / 1.25 g in 1 PACKET (... | Estradiol | ANI Pharmaceuticals, Inc. | 2023-08-24 |
| 72603-0241-30 | 30 PACKET in 1 CARTON (72603-241-30) / .25 g in 1 PACKET (7... | Estradiol | NorthStar Rx LLC | 2023-12-18 |
| 72603-0242-30 | 30 PACKET in 1 CARTON (72603-242-30) / .5 g in 1 PACKET (72... | Estradiol | NorthStar Rx LLC | 2023-12-18 |
| 72603-0243-30 | 30 PACKET in 1 CARTON (72603-243-30) / .75 g in 1 PACKET (7... | Estradiol | NorthStar Rx LLC | 2023-12-18 |
| 72603-0244-30 | 30 PACKET in 1 CARTON (72603-244-30) / 1 g in 1 PACKET (726... | Estradiol | NorthStar Rx LLC | 2023-12-18 |
| 72603-0245-30 | 30 PACKET in 1 CARTON (72603-245-30) / 1.25 g in 1 PACKET (... | Estradiol | NorthStar Rx LLC | 2023-12-18 |
Observed labelers:
Vertical Pharmaceuticals, LLC (10) ·
Amneal Pharmaceuticals NY LLC (5) ·
ANI Pharmaceuticals, Inc. (5) ·
Encube Ethicals, Inc. (5) ·
NorthStar Rx LLC (5) ·
Padagis Israel Pharmaceuticals Ltd (5)
· +2 more — this is the FDA-listed mapping footprint, not sales, inventory, availability, or market share.
🗃️ Sources & Limits
Atlas generation902fddb9-e9c1-4004-bf4c-dba4d51037c7
openFDA export observedJul 14, 2026
RxNorm release07/06/2026
Methodology2026-07-full-catalog-v1
- A shared RxCUI does not prove interchangeability. Products mapped to the same concept are not thereby equivalent or substitutable — equivalence is a separate, product-level determination.
- Listing here does not establish approval or coverage. Appearing in this snapshot is a data observation, not an FDA approval status or a payer coverage decision.
- Missing data never means zero. A silent dataset (no price, no billing code, no utilization) means no observation — not that the real-world value is zero.
- Counts describe the mapping footprint. Product, package, and labeler counts are the FDA-listed mapping footprint in this snapshot — not sales, inventory, availability, or market share.
This product uses publicly available data from the U.S. National Library of Medicine (NLM), National Institutes of Health, Department of Health and Human Services; NLM is not responsible for the product and does not endorse or recommend this or any other product.
Reference information about drug-concept identifiers and public regulatory data — not medical advice. Talk to your pharmacist or prescriber about your own medication.