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Estradiol 0.1 MG/ML Vaginal Cream — RxCUI 310169

RxNorm drug concept · Semantic clinical drug
RxCUI 310169 Semantic clinical drug · SCD ● Current RxNorm concept 19 FDA products 19 package NDCs Snapshot Jul 14, 2026

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Compiled from public NLM RxNorm and FDA (openFDA NDC directory) data sources. Editorial policy

What you’re looking at: the standardized identity of one medicine, as the U.S. drug-data system sees it. Below — every FDA-listed product, package code, price benchmark, and billing code that maps to it.

🗂️ Key Facts

RxCUI310169
Official nameEstradiol 0.1 MG/ML Vaginal Cream
Concept typeSemantic clinical drug (SCD)
RxNorm statusCurrent RxNorm concept
Also known asestradiol 0.01 % Vaginal Cream
FDA products mapped19
Package NDCs mapped19
Reported Medicaid activity (SDUD)335,253 prescriptions · 50 state & territory Medicaid programs · latest period Q4 2025
RxNorm release07/06/2026
Snapshot dataJul 14, 2026

📖 Skip the Codes — Read It in Plain English.

Our pharmacist-built guide to Estradiol Topical: what it is, how it’s used, side effects, and interactions.

📗 Our plain-language guide HelloPharmacist
  • It's designed to ease the moderate to severe hot flashes and night sweats that come with menopause. When estrogen levels drop after menopause, your body's hormonal signals go a bit...
  • What exactly is this medication supposed to do for me?
  • Apply it to your upper thigh — alternating right and left sides each day — and spread it over an area roughly the size of two palm prints. Let it dry completely before getting dres...
  • How do I use the gel correctly so it actually works?
📖 Read our full Estradiol Topical guide →

🕸️ Concept Web — How Estradiol 0.1 MG/ML Vaginal Cream Connects

One RxCUI never lives alone. Follow the path from the raw ingredient down to the exact strength-and-form concepts FDA products carry — every stop is a real RxNorm concept with its own identifier. Hover or focus any chip for what it means.
This page's concept Estradiol 0.1 MG/ML Vaginal Cream RxCUI 310169

Every web starts here: one RxCUI, one fixed meaning in the RxNorm vocabulary.

  1. Ingredients 1

    The active substance itself — no strength, form, or brand attached yet.

    • Estradiol 4083
  2. Brand names 1

    The same medicine's trade names. A brand name alone says nothing about strength or form.

    • Estrace 202619
  3. Dose forms 6

    The ingredient poured into a form — tablet, solution, cream — still without one fixed strength.

    • Estradiol Vaginal Cream 378615
    • Estradiol Vaginal Product 1165763
    • Estradiol Vaginal Cream [Estrace] 890917
    • Estrace Vaginal Product 1169732
    • Vaginal Cream 11103
    • Vaginal Product 1151125
  4. Clinical & branded drugs 3

    Ingredient + strength + dose form. These are the concepts real FDA products actually carry.

Showing up to 8 concepts per family — 11 of 11 stored related concepts drawn.
These are official RxNorm vocabulary relationships — how concepts name and organize the same medicine. They do not establish therapeutic equivalence or substitutability: two concepts appearing in one web is never a statement that products can be swapped.

🔀 Generic ⇄ Brand Crosswalk

The same medicine has an unbranded (generic) identity and one or more brand-name identities — each with its own RxCUI. This is a naming relationship in RxNorm, not a statement that any two products are substitutable.

Generic (Clinical) Concepts

  • Estradiol 0.1 MG/ML SCDC · 323952
  • Estradiol Vaginal Cream SCDF · 378615
  • Estradiol Vaginal Product SCDG · 1165763

Brand-Name Concepts

📦 FDA Products & Package NDCs

19 products · 19 package NDCs
19 package NDCs map to RxCUI 310169 in the current snapshot — up to 50 per page. Each linked NDC opens its full package page.
Package NDC Package Brand / generic name Labeler Marketing start
00093-3541-43 1 TUBE, WITH APPLICATOR in 1 CARTON (0093-3541-43) / 42.5 g... Estradiol Teva Pharmaceuticals USA, Inc. 2018-01-02
00378-8770-35 1 TUBE in 1 CARTON (0378-8770-35) / 42.5 g in 1 TUBE Estradiol Mylan Pharmaceuticals Inc. 2017-12-29
00430-3754-14 36 CARTON in 1 CASE (0430-3754-14) / 1 TUBE, WITH APPLICATO... ESTRACE Allergan, Inc. 2001-07-01
21922-0085-06 1 TUBE in 1 CARTON (21922-085-06) / 42.5 g in 1 TUBE ESTRADIOL VAGINAL Encube Ethicals, Inc. 2025-08-14
42291-0426-42 1 TUBE in 1 CARTON (42291-426-42) / 42.5 g in 1 TUBE Estradiol Vaginal AvKARE 2021-02-16
45802-0097-35 1 TUBE in 1 CARTON (45802-097-35) / 42.5 g in 1 TUBE Estradiol Vaginal Padagis Israel Pharmaceuticals Ltd 2021-01-06
47781-0104-44 1 TUBE, WITH APPLICATOR in 1 CARTON (47781-104-44) / 42.5 g... Estradiol Alvogen Inc. 2018-06-25
50090-2321-00 1 TUBE in 1 CARTON (50090-2321-0) / 42.5 g in 1 TUBE ESTRACE A-S Medication Solutions 2016-03-02
50090-3327-00 1 TUBE, WITH APPLICATOR in 1 CARTON (50090-3327-0) / 42.5 g... Estradiol A-S Medication Solutions 2018-01-11
50090-3645-00 1 TUBE, WITH APPLICATOR in 1 CARTON (50090-3645-0) / 42.5 g... Estradiol A-S Medication Solutions 2018-10-10
50090-6811-00 1 TUBE in 1 CARTON (50090-6811-0) / 42.5 g in 1 TUBE Estradiol Vaginal A-S Medication Solutions 2023-11-08
50090-7266-00 1 TUBE in 1 CARTON (50090-7266-0) / 42.5 g in 1 TUBE Estradiol Vaginal A-S Medication Solutions 2024-10-07
63629-8654-01 1 TUBE in 1 CARTON (63629-8654-1) / 42.5 g in 1 TUBE Estradiol Vaginal Bryant Ranch Prepack 2021-01-06
63629-8713-01 1 TUBE, WITH APPLICATOR in 1 CARTON (63629-8713-1) / 42.5 g... Estradiol Bryant Ranch Prepack 2021-08-19
66993-0002-10 1 TUBE in 1 CARTON (66993-002-10) / 42.5 g in 1 TUBE Estradiol Vaginal Cream Prasco Laboratories 2021-10-01
67296-2258-04 1 TUBE in 1 CARTON (67296-2258-4) / 42.5 g in 1 TUBE Estradiol Vaginal Redpharm Drug 2021-01-06
68071-3796-04 1 TUBE in 1 CARTON (68071-3796-4) / 42.5 g in 1 TUBE Estradiol Vaginal NuCare Pharmaceuticals, Inc. 2025-02-17
71335-2831-01 1 TUBE in 1 CARTON (71335-2831-1) / 42.5 g in 1 TUBE Estradiol Vaginal Bryant Ranch Prepack 2025-10-23
72162-1389-02 1 TUBE in 1 CARTON (72162-1389-2) / 42.5 g in 1 TUBE Estradiol Vaginal Bryant Ranch Prepack 2021-01-06
Observed labelers: A-S Medication Solutions (5) · Bryant Ranch Prepack (4) · Allergan, Inc. (1) · Alvogen Inc. (1) · AvKARE (1) · Encube Ethicals, Inc. (1) · +6 more — this is the FDA-listed mapping footprint, not sales, inventory, availability, or market share.

🗃️ Sources & Limits

Atlas generation902fddb9-e9c1-4004-bf4c-dba4d51037c7
openFDA export observedJul 14, 2026
RxNorm release07/06/2026
Methodology2026-07-full-catalog-v1
  • A shared RxCUI does not prove interchangeability. Products mapped to the same concept are not thereby equivalent or substitutable — equivalence is a separate, product-level determination.
  • Listing here does not establish approval or coverage. Appearing in this snapshot is a data observation, not an FDA approval status or a payer coverage decision.
  • Missing data never means zero. A silent dataset (no price, no billing code, no utilization) means no observation — not that the real-world value is zero.
  • Counts describe the mapping footprint. Product, package, and labeler counts are the FDA-listed mapping footprint in this snapshot — not sales, inventory, availability, or market share.
This product uses publicly available data from the U.S. National Library of Medicine (NLM), National Institutes of Health, Department of Health and Human Services; NLM is not responsible for the product and does not endorse or recommend this or any other product.

Machine-readable JSON

Reference information about drug-concept identifiers and public regulatory data — not medical advice. Talk to your pharmacist or prescriber about your own medication.