Hydrochlorothiazide 25 MG / irbesartan 300 MG Oral Tablet — RxCUI 485471
RxNorm drug concept · Semantic clinical drug
RxCUI 485471
Semantic clinical drug · SCD
● Current RxNorm concept 11 FDA products
40 package NDCs
Snapshot Jul 14, 2026
What you’re looking at: the standardized identity of one medicine, as the U.S. drug-data system sees it. Below — every FDA-listed product, package code, price benchmark, and billing code that maps to it.
🗂️ Key Facts
RxCUI485471
Official nameHydrochlorothiazide 25 MG / irbesartan 300 MG Oral Tablet
Concept typeSemantic clinical drug (SCD)
RxNorm statusCurrent RxNorm concept
Also known asHCTZ 25 MG / irbesartan 300 MG Oral Tablet
FDA products mapped11
Package NDCs mapped40
Reported Medicaid activity (SDUD)3,584 prescriptions · 10 state & territory Medicaid programs · latest period Q4 2025
RxNorm release07/06/2026
Snapshot dataJul 14, 2026
📖 Skip the Codes — Read It in Plain English.
Our pharmacist-built guide to Hydrochlorothiazide: what it is, how it’s used, side effects, and interactions.
📗 Our plain-language guide HelloPharmacist
- It's a water pill — it makes your kidneys flush out extra salt and water, which reduces the amount of fluid your body is holding. That directly lowers your blood pressure and reduc...
- What exactly is hydrochlorothiazide supposed to do for me?
- You can take it either way, but be consistent — take it the same way each time. Food does reduce absorption slightly, but what matters most is that you take it regularly as prescri...
- Should I take it with food or on an empty stomach?
🕸️ Concept Web — How Hydrochlorothiazide 25 MG / irbesartan 300 MG Or... Connects
One RxCUI never lives alone. Follow the path from the raw ingredient down to the exact strength-and-form concepts FDA products carry — every stop is a real RxNorm concept with its own identifier. Hover or focus any chip for what it means.
This page's concept
Hydrochlorothiazide 25 MG / irbesartan 300 MG Oral Tablet
RxCUI 485471 Semantic clinical drug · SCD
Every web starts here: one RxCUI, one fixed meaning in the RxNorm vocabulary.
-
Ingredients 3
The active substance itself — no strength, form, or brand attached yet.
-
Hydrochlorothiazide
5487IN -
Irbesartan
83818IN -
Hydrochlorothiazide / irbesartan
214617MIN
-
Hydrochlorothiazide
-
Dose forms 6
The ingredient poured into a form — tablet, solution, cream — still without one fixed strength.
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Hydrochlorothiazide / irbesartan Oral Tablet
370705SCDF -
Hydrochlorothiazide / irbesartan Oral Product
1162156SCDG -
Hydrochlorothiazide / irbesartan Pill
1162157SCDG -
Oral Tablet
317541DF -
Oral Product
1151131DFG -
Pill
1151133DFG
-
Hydrochlorothiazide / irbesartan Oral Tablet
-
Clinical & branded drugs 2
Ingredient + strength + dose form. These are the concepts real FDA products actually carry.
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Hydrochlorothiazide 25 MG
316049SCDC -
Irbesartan 300 MG
316099SCDC
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Hydrochlorothiazide 25 MG
Showing up to 8 concepts per family — 11 of 11 stored related concepts drawn.
These are official RxNorm vocabulary relationships — how concepts name and organize the same medicine. They do not establish therapeutic equivalence or substitutability: two concepts appearing in one web is never a statement that products can be swapped.
🔀 Generic ⇄ Brand Crosswalk
The same medicine has an unbranded (generic) identity and one or more brand-name identities — each with its own RxCUI. This is a naming relationship in RxNorm, not a statement that any two products are substitutable.
Generic (Clinical) Concepts
-
Hydrochlorothiazide 25 MG
SCDC · 316049 -
Irbesartan 300 MG
SCDC · 316099 -
Hydrochlorothiazide / irbesartan Oral Tablet
SCDF · 370705 -
Hydrochlorothiazide / irbesartan Oral Product
SCDG · 1162156 -
Hydrochlorothiazide / irbesartan Pill
SCDG · 1162157
📦 FDA Products & Package NDCs
11 products · 40 package NDCs
40 package NDCs map to RxCUI 485471 in the current snapshot — up to 50 per page. Each linked NDC opens its full package page.
| Package NDC | Package | Brand / generic name | Labeler | Marketing start |
|---|---|---|---|---|
| 00054-0254-13 | 30 TABLET in 1 BOTTLE (0054-0254-13) | Irbesartan and Hydrochlorothiazide | Hikma Pharmaceuticals USA Inc. | 2012-10-15 |
| 00054-0254-22 | 90 TABLET in 1 BOTTLE (0054-0254-22) | Irbesartan and Hydrochlorothiazide | Hikma Pharmaceuticals USA Inc. | 2012-10-15 |
| 00054-0255-13 | 30 TABLET in 1 BOTTLE (0054-0255-13) | Irbesartan and Hydrochlorothiazide | Hikma Pharmaceuticals USA Inc. | 2012-10-15 |
| 00054-0255-22 | 90 TABLET in 1 BOTTLE (0054-0255-22) | Irbesartan and Hydrochlorothiazide | Hikma Pharmaceuticals USA Inc. | 2012-10-15 |
| 46708-0442-10 | 10 TABLET in 1 BLISTER PACK (46708-442-10) | Irbesartan and Hydrochlorothiazide | Alembic Pharmaceuticals Limited | 2016-05-23 |
| 46708-0442-30 | 30 TABLET in 1 BOTTLE (46708-442-30) | Irbesartan and Hydrochlorothiazide | Alembic Pharmaceuticals Limited | 2016-05-23 |
| 46708-0442-90 | 90 TABLET in 1 BOTTLE (46708-442-90) | Irbesartan and Hydrochlorothiazide | Alembic Pharmaceuticals Limited | 2016-05-23 |
| 46708-0442-91 | 1000 TABLET in 1 BOTTLE (46708-442-91) | Irbesartan and Hydrochlorothiazide | Alembic Pharmaceuticals Limited | 2016-05-23 |
| 46708-0443-10 | 10 TABLET in 1 BLISTER PACK (46708-443-10) | Irbesartan and Hydrochlorothiazide | Alembic Pharmaceuticals Limited | 2016-05-23 |
| 46708-0443-30 | 30 TABLET in 1 BOTTLE (46708-443-30) | Irbesartan and Hydrochlorothiazide | Alembic Pharmaceuticals Limited | 2016-05-23 |
| 46708-0443-90 | 90 TABLET in 1 BOTTLE (46708-443-90) | Irbesartan and Hydrochlorothiazide | Alembic Pharmaceuticals Limited | 2016-05-23 |
| 46708-0443-91 | 1000 TABLET in 1 BOTTLE (46708-443-91) | Irbesartan and Hydrochlorothiazide | Alembic Pharmaceuticals Limited | 2016-05-23 |
| 46708-0444-10 | 10 TABLET in 1 BLISTER PACK (46708-444-10) | Irbesartan and Hydrochlorothiazide | Alembic Pharmaceuticals Limited | 2016-05-23 |
| 46708-0444-30 | 30 TABLET in 1 BOTTLE (46708-444-30) | Irbesartan and Hydrochlorothiazide | Alembic Pharmaceuticals Limited | 2016-05-23 |
| 46708-0444-90 | 90 TABLET in 1 BOTTLE (46708-444-90) | Irbesartan and Hydrochlorothiazide | Alembic Pharmaceuticals Limited | 2016-05-23 |
| 46708-0444-91 | 1000 TABLET in 1 BOTTLE (46708-444-91) | Irbesartan and Hydrochlorothiazide | Alembic Pharmaceuticals Limited | 2016-05-23 |
| 62332-0051-10 | 10 TABLET in 1 BLISTER PACK (62332-051-10) | Irbesartan and Hydrochlorothiazide | Alembic Pharmaceuticals Inc. | 2016-05-23 |
| 62332-0051-30 | 30 TABLET in 1 BOTTLE (62332-051-30) | Irbesartan and Hydrochlorothiazide | Alembic Pharmaceuticals Inc. | 2016-05-23 |
| 62332-0051-90 | 90 TABLET in 1 BOTTLE (62332-051-90) | Irbesartan and Hydrochlorothiazide | Alembic Pharmaceuticals Inc. | 2016-05-23 |
| 62332-0051-91 | 1000 TABLET in 1 BOTTLE (62332-051-91) | Irbesartan and Hydrochlorothiazide | Alembic Pharmaceuticals Inc. | 2016-05-23 |
| 62332-0052-10 | 10 TABLET in 1 BLISTER PACK (62332-052-10) | Irbesartan and Hydrochlorothiazide | Alembic Pharmaceuticals Inc. | 2016-05-23 |
| 62332-0052-30 | 30 TABLET in 1 BOTTLE (62332-052-30) | Irbesartan and Hydrochlorothiazide | Alembic Pharmaceuticals Inc. | 2016-05-23 |
| 62332-0052-90 | 90 TABLET in 1 BOTTLE (62332-052-90) | Irbesartan and Hydrochlorothiazide | Alembic Pharmaceuticals Inc. | 2016-05-23 |
| 62332-0052-91 | 1000 TABLET in 1 BOTTLE (62332-052-91) | Irbesartan and Hydrochlorothiazide | Alembic Pharmaceuticals Inc. | 2016-05-23 |
| 62332-0053-10 | 10 TABLET, FILM COATED in 1 BLISTER PACK (62332-053-10) | Irbesartan and Hydrochlorothiazide | Alembic Pharmaceuticals Inc. | 2016-05-23 |
| 62332-0053-30 | 30 TABLET, FILM COATED in 1 BOTTLE (62332-053-30) | Irbesartan and Hydrochlorothiazide | Alembic Pharmaceuticals Inc. | 2016-05-23 |
| 62332-0053-90 | 90 TABLET, FILM COATED in 1 BOTTLE (62332-053-90) | Irbesartan and Hydrochlorothiazide | Alembic Pharmaceuticals Inc. | 2016-05-23 |
| 62332-0053-91 | 1000 TABLET, FILM COATED in 1 BOTTLE (62332-053-91) | Irbesartan and Hydrochlorothiazide | Alembic Pharmaceuticals Inc. | 2016-05-23 |
| 65862-0629-05 | 500 TABLET, FILM COATED in 1 BOTTLE (65862-629-05) | Irbesartan and Hydrochlorothiazide | Aurobindo Pharma Limited | 2013-02-22 |
| 65862-0629-30 | 30 TABLET, FILM COATED in 1 BOTTLE (65862-629-30) | Irbesartan and Hydrochlorothiazide | Aurobindo Pharma Limited | 2013-02-22 |
| 65862-0629-90 | 90 TABLET, FILM COATED in 1 BOTTLE (65862-629-90) | Irbesartan and Hydrochlorothiazide | Aurobindo Pharma Limited | 2013-02-22 |
| 65862-0629-99 | 1000 TABLET, FILM COATED in 1 BOTTLE (65862-629-99) | Irbesartan and Hydrochlorothiazide | Aurobindo Pharma Limited | 2013-02-22 |
| 65862-0630-05 | 500 TABLET, FILM COATED in 1 BOTTLE (65862-630-05) | Irbesartan and Hydrochlorothiazide | Aurobindo Pharma Limited | 2013-02-22 |
| 65862-0630-30 | 30 TABLET, FILM COATED in 1 BOTTLE (65862-630-30) | Irbesartan and Hydrochlorothiazide | Aurobindo Pharma Limited | 2013-02-22 |
| 65862-0630-90 | 90 TABLET, FILM COATED in 1 BOTTLE (65862-630-90) | Irbesartan and Hydrochlorothiazide | Aurobindo Pharma Limited | 2013-02-22 |
| 65862-0630-99 | 1000 TABLET, FILM COATED in 1 BOTTLE (65862-630-99) | Irbesartan and Hydrochlorothiazide | Aurobindo Pharma Limited | 2013-02-22 |
| 65862-0631-05 | 500 TABLET, FILM COATED in 1 BOTTLE (65862-631-05) | Irbesartan and Hydrochlorothiazide | Aurobindo Pharma Limited | 2016-03-31 |
| 65862-0631-30 | 30 TABLET, FILM COATED in 1 BOTTLE (65862-631-30) | Irbesartan and Hydrochlorothiazide | Aurobindo Pharma Limited | 2016-03-31 |
| 65862-0631-90 | 90 TABLET, FILM COATED in 1 BOTTLE (65862-631-90) | Irbesartan and Hydrochlorothiazide | Aurobindo Pharma Limited | 2016-03-31 |
| 65862-0631-99 | 1000 TABLET, FILM COATED in 1 BOTTLE (65862-631-99) | Irbesartan and Hydrochlorothiazide | Aurobindo Pharma Limited | 2016-03-31 |
Observed labelers:
Alembic Pharmaceuticals Inc. (12) ·
Alembic Pharmaceuticals Limited (12) ·
Aurobindo Pharma Limited (12) ·
Hikma Pharmaceuticals USA Inc. (4)
— this is the FDA-listed mapping footprint, not sales, inventory, availability, or market share.
🗃️ Sources & Limits
Atlas generation902fddb9-e9c1-4004-bf4c-dba4d51037c7
openFDA export observedJul 14, 2026
RxNorm release07/06/2026
Methodology2026-07-full-catalog-v1
- A shared RxCUI does not prove interchangeability. Products mapped to the same concept are not thereby equivalent or substitutable — equivalence is a separate, product-level determination.
- Listing here does not establish approval or coverage. Appearing in this snapshot is a data observation, not an FDA approval status or a payer coverage decision.
- Missing data never means zero. A silent dataset (no price, no billing code, no utilization) means no observation — not that the real-world value is zero.
- Counts describe the mapping footprint. Product, package, and labeler counts are the FDA-listed mapping footprint in this snapshot — not sales, inventory, availability, or market share.
This product uses publicly available data from the U.S. National Library of Medicine (NLM), National Institutes of Health, Department of Health and Human Services; NLM is not responsible for the product and does not endorse or recommend this or any other product.
Reference information about drug-concept identifiers and public regulatory data — not medical advice. Talk to your pharmacist or prescriber about your own medication.