Bisoprolol fumarate 2.5 MG / hydrochlorothiazide 6.25 MG Oral Tablet — RxCUI 854916
RxNorm drug concept · Semantic clinical drug
RxCUI 854916
Semantic clinical drug · SCD
● Current RxNorm concept 34 FDA products
88 package NDCs
Snapshot Jul 14, 2026
What you’re looking at: the standardized identity of one medicine, as the U.S. drug-data system sees it. Below — every FDA-listed product, package code, price benchmark, and billing code that maps to it.
🗂️ Key Facts
RxCUI854916
Official nameBisoprolol fumarate 2.5 MG / hydrochlorothiazide 6.25 MG Oral Tablet
Concept typeSemantic clinical drug (SCD)
RxNorm statusCurrent RxNorm concept
Also known asbisoprolol fumarate 2.5 MG / HCTZ 6.25 MG Oral Tablet
FDA products mapped34
Package NDCs mapped88
Reported Medicaid activity (SDUD)31,610 prescriptions · 37 state & territory Medicaid programs · latest period Q4 2025
RxNorm release07/06/2026
Snapshot dataJul 14, 2026
📖 Skip the Codes — Read It in Plain English.
Our pharmacist-built guide to Hydrochlorothiazide: what it is, how it’s used, side effects, and interactions.
📗 Our plain-language guide HelloPharmacist
- It lowers high blood pressure, which helps reduce the risk of strokes and heart attacks. Some products, such as Inzirqo and the tablets, are also used for swelling from conditions...
- Take it by mouth exactly as prescribed, usually once a day. For swelling, your prescriber may have you take it only some days of the week. Food slightly lowers absorption, so ask m...
- Dizziness, lightheadedness when standing, stomach upset, headache and weakness are the usual ones. Stand up slowly, and be careful with alcohol since it can worsen dizziness. Use s...
- Call for eye pain or sudden vision changes, severe rash or blistering, trouble breathing, severe stomach pain, yellow skin or eyes, or unusual bruising or infections. Also call for...
🕸️ Concept Web — How Bisoprolol fumarate 2.5 MG / hydrochlorothiazide... Connects
One RxCUI never lives alone. Follow the path from the raw ingredient down to the exact strength-and-form concepts FDA products carry — every stop is a real RxNorm concept with its own identifier. Hover or focus any chip for what it means.
This page's concept
Bisoprolol fumarate 2.5 MG / hydrochlorothiazide 6.25 MG Oral Tablet
RxCUI 854916 Semantic clinical drug · SCD
Every web starts here: one RxCUI, one fixed meaning in the RxNorm vocabulary.
-
Ingredients 4
The active substance itself — no strength, form, or brand attached yet.
-
Bisoprolol
19484IN -
Hydrochlorothiazide
5487IN -
Bisoprolol / hydrochlorothiazide
214317MIN -
Bisoprolol fumarate
142146PIN
-
Bisoprolol
-
Brand names 1
The same medicine's trade names. A brand name alone says nothing about strength or form.
-
Ziac
75038BN
-
Ziac
-
Dose forms 13
The ingredient poured into a form — tablet, solution, cream — still without one fixed strength.
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Bisoprolol / hydrochlorothiazide Oral Tablet
371103SCDF -
Bisoprolol fumarate / hydrochlorothiazide Oral Tablet
2648608SCDFP -
Bisoprolol / hydrochlorothiazide Oral Product
1154704SCDG -
Bisoprolol / hydrochlorothiazide Pill
1154705SCDG -
Bisoprolol fumarate / hydrochlorothiazide Oral Product
2662778SCDGP -
Bisoprolol fumarate / hydrochlorothiazide Pill
2662823SCDGP -
Bisoprolol / hydrochlorothiazide Oral Tablet [Ziac]
745976SBDF -
Bisoprolol fumarate / hydrochlorothiazide Oral Tablet [Ziac]
2656127SBDFP - +5 more in this family
-
Bisoprolol / hydrochlorothiazide Oral Tablet
-
Clinical & branded drugs 4
Ingredient + strength + dose form. These are the concepts real FDA products actually carry.
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Bisoprolol fumarate 2.5 MG
854915SCDC -
Hydrochlorothiazide 6.25 MG
316052SCDC -
Bisoprolol fumarate 2.5 MG / hydrochlorothiazide 6.25 MG Oral Tablet [Ziac]
854918SBD -
Bisoprolol fumarate 2.5 MG / hydrochlorothiazide 6.25 MG [Ziac]
854917SBDC
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Bisoprolol fumarate 2.5 MG
Showing up to 8 concepts per family — 17 of 22 stored related concepts drawn.
These are official RxNorm vocabulary relationships — how concepts name and organize the same medicine. They do not establish therapeutic equivalence or substitutability: two concepts appearing in one web is never a statement that products can be swapped.
🔀 Generic ⇄ Brand Crosswalk
The same medicine has an unbranded (generic) identity and one or more brand-name identities — each with its own RxCUI. This is a naming relationship in RxNorm, not a statement that any two products are substitutable.
Generic (Clinical) Concepts
-
Bisoprolol fumarate 2.5 MG
SCDC · 854915 -
Hydrochlorothiazide 6.25 MG
SCDC · 316052 -
Bisoprolol / hydrochlorothiazide Oral Tablet
SCDF · 371103 -
Bisoprolol fumarate / hydrochlorothiazide Oral Tablet
SCDFP · 2648608 -
Bisoprolol / hydrochlorothiazide Oral Product
SCDG · 1154704 -
Bisoprolol / hydrochlorothiazide Pill
SCDG · 1154705 -
Bisoprolol fumarate / hydrochlorothiazide Oral Product
SCDGP · 2662778 -
Bisoprolol fumarate / hydrochlorothiazide Pill
SCDGP · 2662823
Brand-Name Concepts
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Bisoprolol fumarate 2.5 MG / hydrochlorothiazide 6.25 MG Oral Tablet [Ziac]
SBD · 854918 -
Bisoprolol fumarate 2.5 MG / hydrochlorothiazide 6.25 MG [Ziac]
SBDC · 854917 -
Bisoprolol / hydrochlorothiazide Oral Tablet [Ziac]
SBDF · 745976 -
Bisoprolol fumarate / hydrochlorothiazide Oral Tablet [Ziac]
SBDFP · 2656127 -
Ziac Oral Product
SBDG · 1187450 -
Ziac Pill
SBDG · 1187449 -
Ziac
BN · 75038
📦 FDA Products & Package NDCs
34 products · 88 package NDCs
88 package NDCs map to RxCUI 854916 in the current snapshot — up to 50 per page. Each linked NDC opens its full package page.
| Package NDC | Package | Brand / generic name | Labeler | Marketing start |
|---|---|---|---|---|
| 00093-3241-01 | 100 TABLET, FILM COATED in 1 BOTTLE (0093-3241-01) | bisoprolol fumarate and hydrochlorothiazide | Teva Pharmaceuticals USA, Inc. | 2019-08-07 |
| 00093-3242-01 | 100 TABLET, FILM COATED in 1 BOTTLE (0093-3242-01) | bisoprolol fumarate and hydrochlorothiazide | Teva Pharmaceuticals USA, Inc. | 2019-08-07 |
| 00093-3243-56 | 30 TABLET, FILM COATED in 1 BOTTLE (0093-3243-56) | bisoprolol fumarate and hydrochlorothiazide | Teva Pharmaceuticals USA, Inc. | 2019-08-07 |
| 00378-0501-01 | 100 TABLET, FILM COATED in 1 BOTTLE, PLASTIC (0378-0501-01) | Bisoprolol Fumarate and Hydrochlorothiazide | Mylan Pharmaceuticals Inc. | 2021-02-22 |
| 00378-0503-01 | 100 TABLET, FILM COATED in 1 BOTTLE, PLASTIC (0378-0503-01) | Bisoprolol Fumarate and Hydrochlorothiazide | Mylan Pharmaceuticals Inc. | 2021-02-22 |
| 00378-0505-01 | 100 TABLET, FILM COATED in 1 BOTTLE, PLASTIC (0378-0505-01) | Bisoprolol Fumarate and Hydrochlorothiazide | Mylan Pharmaceuticals Inc. | 2021-02-22 |
| 10135-0740-01 | 100 TABLET in 1 BOTTLE (10135-740-01) | Bisoprolol Fumarate and Hydrochlorothiazide | Marlex Pharmaceuticals, Inc. | 2022-05-01 |
| 10135-0740-05 | 500 TABLET in 1 BOTTLE (10135-740-05) | Bisoprolol Fumarate and Hydrochlorothiazide | Marlex Pharmaceuticals, Inc. | 2022-05-01 |
| 10135-0741-01 | 100 TABLET in 1 BOTTLE (10135-741-01) | Bisoprolol Fumarate and Hydrochlorothiazide | Marlex Pharmaceuticals, Inc. | 2022-05-01 |
| 10135-0741-05 | 500 TABLET in 1 BOTTLE (10135-741-05) | Bisoprolol Fumarate and Hydrochlorothiazide | Marlex Pharmaceuticals, Inc. | 2022-05-01 |
| 10135-0742-05 | 500 TABLET in 1 BOTTLE (10135-742-05) | Bisoprolol Fumarate and Hydrochlorothiazide | Marlex Pharmaceuticals, Inc. | 2022-05-01 |
| 10135-0742-30 | 30 TABLET in 1 BOTTLE (10135-742-30) | Bisoprolol Fumarate and Hydrochlorothiazide | Marlex Pharmaceuticals, Inc. | 2022-05-01 |
| 29300-0187-01 | 100 TABLET in 1 BOTTLE, PLASTIC (29300-187-01) | bisoprolol fumarate and hydrochlorothiazide | Unichem Pharmaceuticals (USA), Inc. | 2010-10-12 |
| 29300-0187-05 | 500 TABLET in 1 BOTTLE, PLASTIC (29300-187-05) | bisoprolol fumarate and hydrochlorothiazide | Unichem Pharmaceuticals (USA), Inc. | 2010-10-12 |
| 29300-0187-10 | 1000 TABLET in 1 BOTTLE, PLASTIC (29300-187-10) | bisoprolol fumarate and hydrochlorothiazide | Unichem Pharmaceuticals (USA), Inc. | 2010-10-12 |
| 29300-0187-13 | 30 TABLET in 1 BOTTLE, PLASTIC (29300-187-13) | bisoprolol fumarate and hydrochlorothiazide | Unichem Pharmaceuticals (USA), Inc. | 2010-10-12 |
| 29300-0188-01 | 100 TABLET in 1 BOTTLE, PLASTIC (29300-188-01) | bisoprolol fumarate and hydrochlorothiazide | Unichem Pharmaceuticals (USA), Inc. | 2010-10-12 |
| 29300-0188-05 | 500 TABLET in 1 BOTTLE, PLASTIC (29300-188-05) | bisoprolol fumarate and hydrochlorothiazide | Unichem Pharmaceuticals (USA), Inc. | 2010-10-12 |
| 29300-0188-10 | 1000 TABLET in 1 BOTTLE, PLASTIC (29300-188-10) | bisoprolol fumarate and hydrochlorothiazide | Unichem Pharmaceuticals (USA), Inc. | 2010-10-12 |
| 29300-0188-13 | 30 TABLET in 1 BOTTLE, PLASTIC (29300-188-13) | bisoprolol fumarate and hydrochlorothiazide | Unichem Pharmaceuticals (USA), Inc. | 2010-10-12 |
| 29300-0189-01 | 100 TABLET in 1 BOTTLE, PLASTIC (29300-189-01) | bisoprolol fumarate and hydrochlorothiazide | Unichem Pharmaceuticals (USA), Inc. | 2010-10-12 |
| 29300-0189-05 | 500 TABLET in 1 BOTTLE, PLASTIC (29300-189-05) | bisoprolol fumarate and hydrochlorothiazide | Unichem Pharmaceuticals (USA), Inc. | 2010-10-12 |
| 29300-0189-10 | 1000 TABLET in 1 BOTTLE, PLASTIC (29300-189-10) | bisoprolol fumarate and hydrochlorothiazide | Unichem Pharmaceuticals (USA), Inc. | 2010-10-12 |
| 29300-0189-13 | 30 TABLET in 1 BOTTLE, PLASTIC (29300-189-13) | bisoprolol fumarate and hydrochlorothiazide | Unichem Pharmaceuticals (USA), Inc. | 2010-10-12 |
| 42799-0920-01 | 100 TABLET, FILM COATED in 1 BOTTLE (42799-920-01) | Bisoprolol Fumarate and Hydrochlorothiazide | Edenbridge Pharmaceuticals LLC. | 2019-04-30 |
| 42799-0920-02 | 500 TABLET, FILM COATED in 1 BOTTLE (42799-920-02) | Bisoprolol Fumarate and Hydrochlorothiazide | Edenbridge Pharmaceuticals LLC. | 2019-04-30 |
| 42799-0920-30 | 30 TABLET, FILM COATED in 1 BOTTLE (42799-920-30) | Bisoprolol Fumarate and Hydrochlorothiazide | Edenbridge Pharmaceuticals LLC. | 2019-04-30 |
| 42799-0921-01 | 100 TABLET, FILM COATED in 1 BOTTLE (42799-921-01) | Bisoprolol Fumarate and Hydrochlorothiazide | Edenbridge Pharmaceuticals LLC. | 2019-04-30 |
| 42799-0921-02 | 500 TABLET, FILM COATED in 1 BOTTLE (42799-921-02) | Bisoprolol Fumarate and Hydrochlorothiazide | Edenbridge Pharmaceuticals LLC. | 2019-04-30 |
| 42799-0921-30 | 30 TABLET, FILM COATED in 1 BOTTLE (42799-921-30) | Bisoprolol Fumarate and Hydrochlorothiazide | Edenbridge Pharmaceuticals LLC. | 2019-04-30 |
| 42799-0922-01 | 100 TABLET, FILM COATED in 1 BOTTLE (42799-922-01) | Bisoprolol Fumarate and Hydrochlorothiazide | Edenbridge Pharmaceuticals LLC. | 2019-04-30 |
| 42799-0922-02 | 500 TABLET, FILM COATED in 1 BOTTLE (42799-922-02) | Bisoprolol Fumarate and Hydrochlorothiazide | Edenbridge Pharmaceuticals LLC. | 2019-04-30 |
| 42799-0922-30 | 30 TABLET, FILM COATED in 1 BOTTLE (42799-922-30) | Bisoprolol Fumarate and Hydrochlorothiazide | Edenbridge Pharmaceuticals LLC. | 2019-04-30 |
| 50090-6478-00 | 30 TABLET, FILM COATED in 1 BOTTLE (50090-6478-0) | bisoprolol fumarate and hydrochlorothiazide | A-S Medication Solutions | 2023-05-16 |
| 59651-0678-01 | 100 TABLET, FILM COATED in 1 BOTTLE (59651-678-01) | Bisoprolol Fumarate and Hydrochlorothiazide | Aurobindo Pharma Limited | 2026-01-21 |
| 59651-0678-05 | 500 TABLET, FILM COATED in 1 BOTTLE (59651-678-05) | Bisoprolol Fumarate and Hydrochlorothiazide | Aurobindo Pharma Limited | 2026-01-21 |
| 59651-0678-30 | 30 TABLET, FILM COATED in 1 BOTTLE (59651-678-30) | Bisoprolol Fumarate and Hydrochlorothiazide | Aurobindo Pharma Limited | 2026-01-21 |
| 59651-0679-01 | 100 TABLET, FILM COATED in 1 BOTTLE (59651-679-01) | Bisoprolol Fumarate and Hydrochlorothiazide | Aurobindo Pharma Limited | 2026-01-21 |
| 59651-0679-05 | 500 TABLET, FILM COATED in 1 BOTTLE (59651-679-05) | Bisoprolol Fumarate and Hydrochlorothiazide | Aurobindo Pharma Limited | 2026-01-21 |
| 59651-0679-30 | 30 TABLET, FILM COATED in 1 BOTTLE (59651-679-30) | Bisoprolol Fumarate and Hydrochlorothiazide | Aurobindo Pharma Limited | 2026-01-21 |
| 59651-0680-01 | 100 TABLET, FILM COATED in 1 BOTTLE (59651-680-01) | Bisoprolol Fumarate and Hydrochlorothiazide | Aurobindo Pharma Limited | 2026-01-21 |
| 59651-0680-05 | 500 TABLET, FILM COATED in 1 BOTTLE (59651-680-05) | Bisoprolol Fumarate and Hydrochlorothiazide | Aurobindo Pharma Limited | 2026-01-21 |
| 59651-0680-30 | 30 TABLET, FILM COATED in 1 BOTTLE (59651-680-30) | Bisoprolol Fumarate and Hydrochlorothiazide | Aurobindo Pharma Limited | 2026-01-21 |
| 68462-0878-01 | 100 TABLET, FILM COATED in 1 BOTTLE (68462-878-01) | Bisoprolol Fumarate and Hydrochlorothiazide | GLENMARK PHARMACEUTICALS INC., USA | 2022-01-26 |
| 68462-0878-05 | 500 TABLET, FILM COATED in 1 BOTTLE (68462-878-05) | Bisoprolol Fumarate and Hydrochlorothiazide | GLENMARK PHARMACEUTICALS INC., USA | 2022-01-26 |
| 68462-0878-30 | 30 TABLET, FILM COATED in 1 BOTTLE (68462-878-30) | Bisoprolol Fumarate and Hydrochlorothiazide | GLENMARK PHARMACEUTICALS INC., USA | 2022-01-26 |
| 68462-0879-01 | 100 TABLET, FILM COATED in 1 BOTTLE (68462-879-01) | Bisoprolol Fumarate and Hydrochlorothiazide | GLENMARK PHARMACEUTICALS INC., USA | 2022-01-26 |
| 68462-0879-05 | 500 TABLET, FILM COATED in 1 BOTTLE (68462-879-05) | Bisoprolol Fumarate and Hydrochlorothiazide | GLENMARK PHARMACEUTICALS INC., USA | 2022-01-26 |
| 68462-0879-30 | 30 TABLET, FILM COATED in 1 BOTTLE (68462-879-30) | Bisoprolol Fumarate and Hydrochlorothiazide | GLENMARK PHARMACEUTICALS INC., USA | 2022-01-26 |
| 68462-0880-01 | 100 TABLET, FILM COATED in 1 BOTTLE (68462-880-01) | Bisoprolol Fumarate and Hydrochlorothiazide | GLENMARK PHARMACEUTICALS INC., USA | 2022-01-26 |
Observed labelers:
Unichem Pharmaceuticals (USA), Inc. (12) ·
ANI Pharmaceuticals, Inc. (9) ·
Aurobindo Pharma Limited (9) ·
Bryant Ranch Prepack (9) ·
Edenbridge Pharmaceuticals LLC. (9) ·
GLENMARK PHARMACEUTICALS INC., USA (9)
· +6 more — this is the FDA-listed mapping footprint, not sales, inventory, availability, or market share.
🗃️ Sources & Limits
Atlas generation902fddb9-e9c1-4004-bf4c-dba4d51037c7
openFDA export observedJul 14, 2026
RxNorm release07/06/2026
Methodology2026-07-full-catalog-v1
- A shared RxCUI does not prove interchangeability. Products mapped to the same concept are not thereby equivalent or substitutable — equivalence is a separate, product-level determination.
- Listing here does not establish approval or coverage. Appearing in this snapshot is a data observation, not an FDA approval status or a payer coverage decision.
- Missing data never means zero. A silent dataset (no price, no billing code, no utilization) means no observation — not that the real-world value is zero.
- Counts describe the mapping footprint. Product, package, and labeler counts are the FDA-listed mapping footprint in this snapshot — not sales, inventory, availability, or market share.
This product uses publicly available data from the U.S. National Library of Medicine (NLM), National Institutes of Health, Department of Health and Human Services; NLM is not responsible for the product and does not endorse or recommend this or any other product.
Reference information about drug-concept identifiers and public regulatory data — not medical advice. Talk to your pharmacist or prescriber about your own medication.