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Atovaquone 62.5 MG / proguanil hydrochloride 25 MG Oral Tablet — RxCUI 864681

RxNorm drug concept · Semantic clinical drug
RxCUI 864681 Semantic clinical drug · SCD ● Current RxNorm concept 6 FDA products 8 package NDCs Snapshot Jul 14, 2026

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Compiled from public NLM RxNorm and FDA (openFDA NDC directory) data sources. Editorial policy

What you’re looking at: the standardized identity of one medicine, as the U.S. drug-data system sees it. Below — every FDA-listed product, package code, price benchmark, and billing code that maps to it.

🗂️ Key Facts

RxCUI864681
Official nameAtovaquone 62.5 MG / proguanil hydrochloride 25 MG Oral Tablet
Concept typeSemantic clinical drug (SCD)
RxNorm statusCurrent RxNorm concept
Also known asatovaquone 62.5 MG / proguanil HCl 25 MG Oral Tablet
FDA products mapped6
Package NDCs mapped8
Reported Medicaid activity (SDUD)30,019 prescriptions · 36 state & territory Medicaid programs · latest period Q4 2025
RxNorm release07/06/2026
Snapshot dataJul 14, 2026

📖 Skip the Codes — Read It in Plain English.

Our pharmacist-built guide to Atovaquone and Proguanil: what it is, how it’s used, side effects, and interactions.

📗 Our plain-language guide HelloPharmacist
  • It actually does both, depending on why your doctor prescribed it. If you're traveling to an area where malaria is common, you take it starting a day or two before you leave, every...
  • What exactly does this medicine do — does it prevent malaria or treat it?
  • Yes, it genuinely matters. One of the two ingredients, atovaquone, is barely absorbed on an empty stomach — fat in food dramatically increases how much gets into your bloodstream,...
  • Why do I have to take it with food? Does it really matter?
📖 Read our full Atovaquone and Proguanil guide →

🕸️ Concept Web — How Atovaquone 62.5 MG / proguanil hydrochloride 25... Connects

One RxCUI never lives alone. Follow the path from the raw ingredient down to the exact strength-and-form concepts FDA products carry — every stop is a real RxNorm concept with its own identifier. Hover or focus any chip for what it means.
This page's concept Atovaquone 62.5 MG / proguanil hydrochloride 25 MG Oral Tablet RxCUI 864681

Every web starts here: one RxCUI, one fixed meaning in the RxNorm vocabulary.

  1. Ingredients 4

    The active substance itself — no strength, form, or brand attached yet.

    • Atovaquone 60212
    • Proguanil 2382
    • Atovaquone / proguanil 284623
    • Proguanil hydrochloride 142428
  2. Brand names 1

    The same medicine's trade names. A brand name alone says nothing about strength or form.

    • Malarone 153767
  3. Dose forms 13

    The ingredient poured into a form — tablet, solution, cream — still without one fixed strength.

    • Atovaquone / proguanil Oral Tablet 370623
    • Atovaquone / proguanil hydrochloride Oral Tablet 2648120
    • Atovaquone / proguanil Oral Product 1154383
    • Atovaquone / proguanil Pill 1154384
    • Atovaquone / proguanil hydrochloride Oral Product 2662837
    • Atovaquone / proguanil hydrochloride Pill 2661601
    • Atovaquone / proguanil Oral Tablet [Malarone] 864678
    • Atovaquone / proguanil hydrochloride Oral Tablet [Malarone] 2655210
    • +5 more in this family
  4. Clinical & branded drugs 4

    Ingredient + strength + dose form. These are the concepts real FDA products actually carry.

Showing up to 8 concepts per family — 17 of 22 stored related concepts drawn.
These are official RxNorm vocabulary relationships — how concepts name and organize the same medicine. They do not establish therapeutic equivalence or substitutability: two concepts appearing in one web is never a statement that products can be swapped.

🔀 Generic ⇄ Brand Crosswalk

The same medicine has an unbranded (generic) identity and one or more brand-name identities — each with its own RxCUI. This is a naming relationship in RxNorm, not a statement that any two products are substitutable.

Generic (Clinical) Concepts

  • Atovaquone 62.5 MG SCDC · 329301
  • Proguanil hydrochloride 25 MG SCDC · 864680
  • Atovaquone / proguanil Oral Tablet SCDF · 370623
  • Atovaquone / proguanil hydrochloride Oral Tablet SCDFP · 2648120
  • Atovaquone / proguanil Oral Product SCDG · 1154383
  • Atovaquone / proguanil Pill SCDG · 1154384
  • Atovaquone / proguanil hydrochloride Oral Product SCDGP · 2662837
  • Atovaquone / proguanil hydrochloride Pill SCDGP · 2661601

Brand-Name Concepts

  • Atovaquone 62.5 MG / proguanil hydrochloride 25 MG Oral Tablet [Malarone] SBD · 864685
  • Atovaquone 62.5 MG / proguanil hydrochloride 25 MG [Malarone] SBDC · 864683
  • Atovaquone / proguanil Oral Tablet [Malarone] SBDF · 864678
  • Atovaquone / proguanil hydrochloride Oral Tablet [Malarone] SBDFP · 2655210
  • Malarone Oral Product SBDG · 1179721
  • Malarone Pill SBDG · 1179722
  • Malarone BN · 153767

📦 FDA Products & Package NDCs

6 products · 8 package NDCs
8 package NDCs map to RxCUI 864681 in the current snapshot — up to 50 per page. Each linked NDC opens its full package page.
Package NDC Package Brand / generic name Labeler Marketing start
00173-0675-01 100 TABLET, FILM COATED in 1 BOTTLE (0173-0675-01) MALARONE GlaxoSmithKline LLC 2000-07-26
00173-0675-02 24 TABLET, FILM COATED in 1 DOSE PACK (0173-0675-02) MALARONE GlaxoSmithKline LLC 2000-07-26
00173-0676-01 100 TABLET, FILM COATED in 1 BOTTLE (0173-0676-01) MALARONE GlaxoSmithKline LLC 2000-07-26
00378-4160-01 100 TABLET, FILM COATED in 1 BOTTLE, PLASTIC (0378-4160-01) Atovaquone and Proguanil Hydrochloride Mylan Pharmaceuticals Inc. 2014-05-28
00378-4162-01 100 TABLET, FILM COATED in 1 BOTTLE, PLASTIC (0378-4162-01) Atovaquone and Proguanil Hydrochloride Mylan Pharmaceuticals Inc. 2014-05-28
68462-0402-01 100 TABLET, FILM COATED in 1 BOTTLE (68462-402-01) Atovaquone and Proguanil Hydrochloride Pediatric Glenmark Pharmaceuticals Inc.,USA 2015-04-08
68462-0404-01 100 TABLET, FILM COATED in 1 BOTTLE (68462-404-01) Atovaquone and Proguanil Hydrochloride Glenmark Pharmaceuticals Inc.,USA 2011-09-15
68462-0404-67 2 BLISTER PACK in 1 CARTON (68462-404-67) / 12 TABLET, FILM... Atovaquone and Proguanil Hydrochloride Glenmark Pharmaceuticals Inc.,USA 2011-09-15
Observed labelers: GlaxoSmithKline LLC (3) · Glenmark Pharmaceuticals Inc.,USA (3) · Mylan Pharmaceuticals Inc. (2) — this is the FDA-listed mapping footprint, not sales, inventory, availability, or market share.

🗃️ Sources & Limits

Atlas generation902fddb9-e9c1-4004-bf4c-dba4d51037c7
openFDA export observedJul 14, 2026
RxNorm release07/06/2026
Methodology2026-07-full-catalog-v1
  • A shared RxCUI does not prove interchangeability. Products mapped to the same concept are not thereby equivalent or substitutable — equivalence is a separate, product-level determination.
  • Listing here does not establish approval or coverage. Appearing in this snapshot is a data observation, not an FDA approval status or a payer coverage decision.
  • Missing data never means zero. A silent dataset (no price, no billing code, no utilization) means no observation — not that the real-world value is zero.
  • Counts describe the mapping footprint. Product, package, and labeler counts are the FDA-listed mapping footprint in this snapshot — not sales, inventory, availability, or market share.
This product uses publicly available data from the U.S. National Library of Medicine (NLM), National Institutes of Health, Department of Health and Human Services; NLM is not responsible for the product and does not endorse or recommend this or any other product.

Machine-readable JSON

Reference information about drug-concept identifiers and public regulatory data — not medical advice. Talk to your pharmacist or prescriber about your own medication.