Dextromethorphan hydrobromide 3 MG/ML / promethazine hydrochloride 1.25 MG/ML Oral Solutio... — RxCUI 991528
RxNorm drug concept · Semantic clinical drug
RxCUI 991528
Semantic clinical drug · SCD
● Current RxNorm concept 18 FDA products
27 package NDCs
Snapshot Jul 14, 2026
What you’re looking at: the standardized identity of one medicine, as the U.S. drug-data system sees it. Below — every FDA-listed product, package code, price benchmark, and billing code that maps to it.
🗂️ Key Facts
RxCUI991528
Official nameDextromethorphan hydrobromide 3 MG/ML / promethazine hydrochloride 1.25 MG/ML Oral Solution
Concept typeSemantic clinical drug (SCD)
RxNorm statusCurrent RxNorm concept
Also known asdextromethorphan HBr 15 MG / promethazine HCl 6.25 MG per 5 ML Oral Solution; promethazine HCl 6.25 MG / dextromethorphan HBr 15 MG in 5 mL Oral Solution
FDA products mapped18
Package NDCs mapped27
Reported Medicaid activity (SDUD)778,055 prescriptions · 37 state & territory Medicaid programs · latest period Q4 2025
RxNorm release07/06/2026
Snapshot dataJul 14, 2026
📖 Skip the Codes — Read It in Plain English.
Our pharmacist-built guide to Promethazine: what it is, how it’s used, side effects, and interactions.
📗 Our plain-language guide HelloPharmacist
- Promethazine has several uses. It's most commonly used for allergy symptoms like hay fever, hives, and itchy or watery eyes. It's also used to prevent or treat nausea and vomiting...
- Yes — drowsiness is the most common and expected side effect. You should avoid driving, operating machinery, or doing anything that requires sharp focus until you know how it affec...
- Will promethazine make me really drowsy?
- Promethazine is strictly off-limits for children under 2 years old — it can slow or stop breathing, and there have been fatalities reported in this age group. For children 2 and ol...
🕸️ Concept Web — How Dextromethorphan hydrobromide 3 MG/ML / prometha... Connects
One RxCUI never lives alone. Follow the path from the raw ingredient down to the exact strength-and-form concepts FDA products carry — every stop is a real RxNorm concept with its own identifier. Hover or focus any chip for what it means.
This page's concept
Dextromethorphan hydrobromide 3 MG/ML / promethazine hydrochloride 1.25 MG/ML Oral Solution
RxCUI 991528 Semantic clinical drug · SCD
Every web starts here: one RxCUI, one fixed meaning in the RxNorm vocabulary.
-
Ingredients 5
The active substance itself — no strength, form, or brand attached yet.
-
Dextromethorphan
3289IN -
Promethazine
8745IN -
Dextromethorphan / promethazine
214491MIN -
Dextromethorphan hydrobromide
102490PIN -
Promethazine hydrochloride
142445PIN
-
Dextromethorphan
-
Dose forms 9
The ingredient poured into a form — tablet, solution, cream — still without one fixed strength.
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Dextromethorphan / promethazine Oral Solution
393371SCDF -
Dextromethorphan hydrobromide / promethazine hydrochloride Oral Solution
2646268SCDFP -
Dextromethorphan / promethazine Oral Liquid Product
1155208SCDG -
Dextromethorphan / promethazine Oral Product
1155209SCDG -
Dextromethorphan hydrobromide / promethazine hydrochloride Oral Liquid Product
2661850SCDGP -
Dextromethorphan hydrobromide / promethazine hydrochloride Oral Product
2661651SCDGP -
Oral Solution
316968DF -
Oral Liquid Product
1151137DFG - +1 more in this family
-
Dextromethorphan / promethazine Oral Solution
-
Clinical & branded drugs 2
Ingredient + strength + dose form. These are the concepts real FDA products actually carry.
-
Dextromethorphan hydrobromide 3 MG/ML
1010945SCDC -
Promethazine hydrochloride 1.25 MG/ML
991457SCDC
-
Dextromethorphan hydrobromide 3 MG/ML
Showing up to 8 concepts per family — 15 of 16 stored related concepts drawn.
These are official RxNorm vocabulary relationships — how concepts name and organize the same medicine. They do not establish therapeutic equivalence or substitutability: two concepts appearing in one web is never a statement that products can be swapped.
🔀 Generic ⇄ Brand Crosswalk
The same medicine has an unbranded (generic) identity and one or more brand-name identities — each with its own RxCUI. This is a naming relationship in RxNorm, not a statement that any two products are substitutable.
Generic (Clinical) Concepts
-
Dextromethorphan hydrobromide 3 MG/ML
SCDC · 1010945 -
Promethazine hydrochloride 1.25 MG/ML
SCDC · 991457 -
Dextromethorphan / promethazine Oral Solution
SCDF · 393371 -
Dextromethorphan hydrobromide / promethazine hydrochloride Oral Solution
SCDFP · 2646268 -
Dextromethorphan / promethazine Oral Liquid Product
SCDG · 1155208 -
Dextromethorphan / promethazine Oral Product
SCDG · 1155209 -
Dextromethorphan hydrobromide / promethazine hydrochloride Oral Liquid Product
SCDGP · 2661850 -
Dextromethorphan hydrobromide / promethazine hydrochloride Oral Product
SCDGP · 2661651
📦 FDA Products & Package NDCs
18 products · 27 package NDCs
27 package NDCs map to RxCUI 991528 in the current snapshot — up to 50 per page. Each linked NDC opens its full package page.
| Package NDC | Package | Brand / generic name | Labeler | Marketing start |
|---|---|---|---|---|
| 00116-4024-16 | 473 mL in 1 BOTTLE, PLASTIC (0116-4024-16) | Promethazine Hydrochloride and Dextromethorphan Hydrobromide | Xttrium Laboratories, Inc | 2025-04-07 |
| 00121-1070-04 | 118 mL in 1 BOTTLE (0121-1070-04) | Promethazine DM | PAI Holdings, LLC dba PAI Pharma | 2025-06-04 |
| 00121-1070-16 | 473 mL in 1 BOTTLE (0121-1070-16) | Promethazine DM | PAI Holdings, LLC dba PAI Pharma | 2025-06-04 |
| 00713-0780-75 | 473 mL in 1 BOTTLE, PLASTIC (0713-0780-75) | Promethazine Hydrochloride and Dextromethorphan Hydrobromide | Cosette Pharmaceuticals, Inc. | 2025-09-19 |
| 17856-4024-01 | 72 CUP, UNIT-DOSE in 1 CASE (17856-4024-1) / 5 mL in 1 CUP,... | Promethazine Hydrochloride and Dextromethorphan Hydrobromide | Atlantic Biologicals Corp. | 2026-04-24 |
| 27808-0057-01 | 473 mL in 1 BOTTLE, PLASTIC (27808-057-01) | Promethazine Hydrochloride and Dextromethorphan Hydrobromide | Cranbury Pharmaceuticals, LLC | 2021-11-15 |
| 31722-0692-11 | 118 mL in 1 BOTTLE (31722-692-11) | PROMETHAZINE HYDROCHLORIDE AND DEXTROMETHORPHAN HYDROBROMIDE | Camber Pharmaceuticals, Inc. | 2026-03-12 |
| 31722-0692-47 | 473 mL in 1 BOTTLE (31722-692-47) | PROMETHAZINE HYDROCHLORIDE AND DEXTROMETHORPHAN HYDROBROMIDE | Camber Pharmaceuticals, Inc. | 2026-03-12 |
| 50090-6467-00 | 473 mL in 1 BOTTLE, PLASTIC (50090-6467-0) | Promethazine Hydrochloride and Dextromethorphan Hydrobromide | A-S Medication Solutions | 2023-05-08 |
| 50090-6467-01 | 473 mL in 1 BOTTLE, PLASTIC (50090-6467-1) | Promethazine Hydrochloride and Dextromethorphan Hydrobromide | A-S Medication Solutions | 2023-05-08 |
| 50090-6585-00 | 118 mL in 1 BOTTLE (50090-6585-0) | Promethazine Hydrochloride and Dextromethorphan Hydrobromide Oral | A-S Medication Solutions | 2023-08-09 |
| 50090-6755-00 | 473 mL in 1 BOTTLE, PLASTIC (50090-6755-0) | Promethazine Hydrochloride and Dextromethorphan Hydrobromide | A-S Medication Solutions | 2023-10-17 |
| 50090-6755-01 | 4 BOTTLE in 1 BOTTLE (50090-6755-1) / 118 mL in 1 BOTTLE | Promethazine Hydrochloride and Dextromethorphan Hydrobromide | A-S Medication Solutions | 2024-02-05 |
| 50090-7658-00 | 473 mL in 1 BOTTLE, PLASTIC (50090-7658-0) | Promethazine Hydrochloride and Dextromethorphan Hydrobromide | A-S Medication Solutions | 2025-09-22 |
| 50090-7658-01 | 473 mL in 1 BOTTLE, PLASTIC (50090-7658-1) | Promethazine Hydrochloride and Dextromethorphan Hydrobromide | A-S Medication Solutions | 2025-09-22 |
| 62559-0758-04 | 118 mL in 1 BOTTLE (62559-758-04) | Promethazine Hydrochloride and Dextromethorphan Hydrobromide | ANI Pharmaceuticals, Inc. | 2024-09-05 |
| 62559-0758-16 | 473 mL in 1 BOTTLE (62559-758-16) | Promethazine Hydrochloride and Dextromethorphan Hydrobromide | ANI Pharmaceuticals, Inc. | 2024-09-05 |
| 65162-0680-86 | 118 mL in 1 BOTTLE (65162-680-86) | Promethazine Hydrochloride and Dextromethorphan Hydrobromide | Amneal Pharmaceuticals LLC | 2011-03-04 |
| 65162-0680-90 | 473 mL in 1 BOTTLE (65162-680-90) | Promethazine Hydrochloride and Dextromethorphan Hydrobromide | Amneal Pharmaceuticals LLC | 2011-03-04 |
| 68071-3551-04 | 118 mL in 1 BOTTLE (68071-3551-4) | Promethazine Hydrochloride and Dextromethorphan Hydrobromide Oral Solution | NuCare Pharmaceuticals,Inc. | 2023-12-01 |
| 68788-8100-01 | 118 mL in 1 BOTTLE (68788-8100-1) | Promethazine Hydrochloride and Dextromethorphan Hydrobromide Oral Solution | Preferred Pharmaceuticals Inc. | 2021-10-08 |
| 71205-0654-04 | 118 mL in 1 BOTTLE (71205-654-04) | Promethazine Hydrochloride and Dextromethorphan Hydrobromide Oral Solution | Proficient Rx LP | 2022-04-26 |
| 72162-2039-02 | 473 mL in 1 BOTTLE, PLASTIC (72162-2039-2) | Promethazine Hydrochloride and Dextromethorphan Hydrobromide | Bryant Ranch Prepack | 2023-06-06 |
| 72888-0038-01 | 473 mL in 1 BOTTLE (72888-038-01) | Promethazine Hydrochloride and Dextromethorphan Hydrobromide | Advagen Pharma Ltd | 2026-06-23 |
| 72888-0038-02 | 118 mL in 1 BOTTLE (72888-038-02) | Promethazine Hydrochloride and Dextromethorphan Hydrobromide | Advagen Pharma Ltd | 2026-06-23 |
| 76420-0335-04 | 118 mL in 1 BOTTLE (76420-335-04) | Promethazine Hydrochloride and Dextromethorphan Hydrobromide | Asclemed USA, Inc. | 2025-04-22 |
| 76420-0335-16 | 473 mL in 1 BOTTLE (76420-335-16) | Promethazine Hydrochloride and Dextromethorphan Hydrobromide | Asclemed USA, Inc. | 2025-04-22 |
Observed labelers:
A-S Medication Solutions (7) ·
Advagen Pharma Ltd (2) ·
Amneal Pharmaceuticals LLC (2) ·
ANI Pharmaceuticals, Inc. (2) ·
Asclemed USA, Inc. (2) ·
Camber Pharmaceuticals, Inc. (2)
· +9 more — this is the FDA-listed mapping footprint, not sales, inventory, availability, or market share.
🗃️ Sources & Limits
Atlas generation902fddb9-e9c1-4004-bf4c-dba4d51037c7
openFDA export observedJul 14, 2026
RxNorm release07/06/2026
Methodology2026-07-full-catalog-v1
- A shared RxCUI does not prove interchangeability. Products mapped to the same concept are not thereby equivalent or substitutable — equivalence is a separate, product-level determination.
- Listing here does not establish approval or coverage. Appearing in this snapshot is a data observation, not an FDA approval status or a payer coverage decision.
- Missing data never means zero. A silent dataset (no price, no billing code, no utilization) means no observation — not that the real-world value is zero.
- Counts describe the mapping footprint. Product, package, and labeler counts are the FDA-listed mapping footprint in this snapshot — not sales, inventory, availability, or market share.
This product uses publicly available data from the U.S. National Library of Medicine (NLM), National Institutes of Health, Department of Health and Human Services; NLM is not responsible for the product and does not endorse or recommend this or any other product.
Reference information about drug-concept identifiers and public regulatory data — not medical advice. Talk to your pharmacist or prescriber about your own medication.