Promethazine hydrochloride 25 MG Oral Tablet — RxCUI 992447
RxNorm drug concept · Semantic clinical drug
RxCUI 992447
Semantic clinical drug · SCD
● Current RxNorm concept 66 FDA products
241 package NDCs
Snapshot Jul 14, 2026
What you’re looking at: the standardized identity of one medicine, as the U.S. drug-data system sees it. Below — every FDA-listed product, package code, price benchmark, and billing code that maps to it.
🗂️ Key Facts
RxCUI992447
Official namePromethazine hydrochloride 25 MG Oral Tablet
Concept typeSemantic clinical drug (SCD)
RxNorm statusCurrent RxNorm concept
Also known aspromethazine HCl 25 MG Oral Tablet
FDA products mapped66
Package NDCs mapped241
Reported Medicaid activity (SDUD)773,569 prescriptions · 52 state & territory Medicaid programs · latest period Q4 2025
RxNorm release07/06/2026
Snapshot dataJul 14, 2026
📖 Skip the Codes — Read It in Plain English.
Our pharmacist-built guide to Promethazine: what it is, how it’s used, side effects, and interactions.
📗 Our plain-language guide HelloPharmacist
- It treats allergy symptoms like allergic rhinitis and hives, motion sickness, and nausea and vomiting around surgery. It is also used for sedation. Which uses apply depends on the...
- Very likely. Drowsiness is its most common effect. Don't drive or use machinery until you know how it affects you, and avoid alcohol and other sedating medicines.
- Not if the child is under 2. It can cause fatal slowed breathing in that age group. For children 2 and older, it needs real caution and the lowest effective dose, so only use it as...
- Use an accurate measuring device, not a kitchen teaspoon, which can lead to overdose. I can give you an oral syringe or dosing cup and show you how to measure.
🕸️ Concept Web — How Promethazine hydrochloride 25 MG Oral Tablet Connects
One RxCUI never lives alone. Follow the path from the raw ingredient down to the exact strength-and-form concepts FDA products carry — every stop is a real RxNorm concept with its own identifier. Hover or focus any chip for what it means.
This page's concept
Promethazine hydrochloride 25 MG Oral Tablet
RxCUI 992447 Semantic clinical drug · SCD
Every web starts here: one RxCUI, one fixed meaning in the RxNorm vocabulary.
-
Ingredients 2
The active substance itself — no strength, form, or brand attached yet.
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Promethazine
8745IN -
Promethazine hydrochloride
142445PIN
-
Promethazine
-
Dose forms 9
The ingredient poured into a form — tablet, solution, cream — still without one fixed strength.
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Promethazine Oral Tablet
373630SCDF -
Promethazine hydrochloride Oral Tablet
2646192SCDFP -
Promethazine Oral Product
1162312SCDG -
Promethazine Pill
1162313SCDG -
Promethazine hydrochloride Oral Product
2660458SCDGP -
Promethazine hydrochloride Pill
2659912SCDGP -
Oral Tablet
317541DF -
Oral Product
1151131DFG - +1 more in this family
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Promethazine Oral Tablet
-
Clinical & branded drugs 1
Ingredient + strength + dose form. These are the concepts real FDA products actually carry.
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Promethazine hydrochloride 25 MG
861577SCDC
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Promethazine hydrochloride 25 MG
Showing up to 8 concepts per family — 11 of 12 stored related concepts drawn.
These are official RxNorm vocabulary relationships — how concepts name and organize the same medicine. They do not establish therapeutic equivalence or substitutability: two concepts appearing in one web is never a statement that products can be swapped.
🔀 Generic ⇄ Brand Crosswalk
The same medicine has an unbranded (generic) identity and one or more brand-name identities — each with its own RxCUI. This is a naming relationship in RxNorm, not a statement that any two products are substitutable.
Generic (Clinical) Concepts
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Promethazine hydrochloride 25 MG
SCDC · 861577 -
Promethazine Oral Tablet
SCDF · 373630 -
Promethazine hydrochloride Oral Tablet
SCDFP · 2646192 -
Promethazine Oral Product
SCDG · 1162312 -
Promethazine Pill
SCDG · 1162313 -
Promethazine hydrochloride Oral Product
SCDGP · 2660458 -
Promethazine hydrochloride Pill
SCDGP · 2659912
📦 FDA Products & Package NDCs
66 products · 241 package NDCs
241 package NDCs map to RxCUI 992447 in the current snapshot — up to 50 per page. Each linked NDC opens its full package page.
| Package NDC | Package | Brand / generic name | Labeler | Marketing start |
|---|---|---|---|---|
| 00591-5307-01 | 100 TABLET in 1 BOTTLE, PLASTIC (0591-5307-01) | Promethazine Hydrochloride | Actavis Pharma, Inc. | 1973-09-19 |
| 00591-5307-10 | 1000 TABLET in 1 BOTTLE, PLASTIC (0591-5307-10) | Promethazine Hydrochloride | Actavis Pharma, Inc. | 1973-09-19 |
| 00591-5319-01 | 100 TABLET in 1 BOTTLE, PLASTIC (0591-5319-01) | Promethazine Hydrochloride | Actavis Pharma, Inc. | 1973-09-21 |
| 00615-8154-39 | 30 TABLET in 1 BLISTER PACK (0615-8154-39) | Promethazine Hydrochloride | NCS HealthCare of KY, LLC dba Vangard Labs | 2018-07-02 |
| 00904-7304-61 | 100 BLISTER PACK in 1 CARTON (0904-7304-61) / 1 TABLET in 1... | Promethazine Hydrochloride | Major Pharmaceuticals | 2023-04-17 |
| 10702-0002-01 | 100 TABLET in 1 BOTTLE (10702-002-01) | PROMETHAZINE HYDROCHLORIDE | KVK-Tech, Inc. | 2007-05-04 |
| 10702-0002-10 | 1000 TABLET in 1 BOTTLE (10702-002-10) | PROMETHAZINE HYDROCHLORIDE | KVK-Tech, Inc. | 2007-05-04 |
| 10702-0003-01 | 100 TABLET in 1 BOTTLE (10702-003-01) | PROMETHAZINE HYDROCHLORIDE | KVK-Tech, Inc. | 2006-07-31 |
| 10702-0003-10 | 1000 TABLET in 1 BOTTLE (10702-003-10) | PROMETHAZINE HYDROCHLORIDE | KVK-Tech, Inc. | 2006-07-31 |
| 10702-0003-50 | 500 TABLET in 1 BOTTLE (10702-003-50) | PROMETHAZINE HYDROCHLORIDE | KVK-Tech, Inc. | 2016-05-19 |
| 10702-0004-01 | 100 TABLET in 1 BOTTLE (10702-004-01) | PROMETHAZINE HYDROCHLORIDE | KVK-Tech, Inc. | 2006-07-31 |
| 10702-0004-10 | 1000 TABLET in 1 BOTTLE (10702-004-10) | PROMETHAZINE HYDROCHLORIDE | KVK-Tech, Inc. | 2006-07-31 |
| 43063-0405-04 | 4 TABLET in 1 BOTTLE, PLASTIC (43063-405-04) | Promethazine Hydrochloride | PD-Rx Pharmaceuticals, Inc. | 2012-02-21 |
| 43063-0405-05 | 5 TABLET in 1 BOTTLE, PLASTIC (43063-405-05) | Promethazine Hydrochloride | PD-Rx Pharmaceuticals, Inc. | 2012-02-21 |
| 43063-0405-06 | 6 TABLET in 1 BOTTLE, PLASTIC (43063-405-06) | Promethazine Hydrochloride | PD-Rx Pharmaceuticals, Inc. | 2012-02-21 |
| 43063-0405-10 | 10 TABLET in 1 BOTTLE, PLASTIC (43063-405-10) | Promethazine Hydrochloride | PD-Rx Pharmaceuticals, Inc. | 2012-02-21 |
| 43063-0405-12 | 12 TABLET in 1 BOTTLE, PLASTIC (43063-405-12) | Promethazine Hydrochloride | PD-Rx Pharmaceuticals, Inc. | 2012-02-21 |
| 43063-0405-15 | 15 TABLET in 1 BOTTLE, PLASTIC (43063-405-15) | Promethazine Hydrochloride | PD-Rx Pharmaceuticals, Inc. | 2012-02-21 |
| 43063-0405-20 | 20 TABLET in 1 BOTTLE, PLASTIC (43063-405-20) | Promethazine Hydrochloride | PD-Rx Pharmaceuticals, Inc. | 2012-02-21 |
| 43063-0405-25 | 25 TABLET in 1 BOTTLE, PLASTIC (43063-405-25) | Promethazine Hydrochloride | PD-Rx Pharmaceuticals, Inc. | 2012-02-21 |
| 43063-0405-30 | 30 TABLET in 1 BOTTLE, PLASTIC (43063-405-30) | Promethazine Hydrochloride | PD-Rx Pharmaceuticals, Inc. | 2012-02-21 |
| 43063-0405-60 | 60 TABLET in 1 BOTTLE, PLASTIC (43063-405-60) | Promethazine Hydrochloride | PD-Rx Pharmaceuticals, Inc. | 2012-02-21 |
| 43063-0405-79 | 1 TABLET in 1 BOTTLE, PLASTIC (43063-405-79) | Promethazine Hydrochloride | PD-Rx Pharmaceuticals, Inc. | 2012-02-21 |
| 43063-0874-01 | 100 TABLET in 1 BOTTLE, PLASTIC (43063-874-01) | PROMETHAZINE HYDROCHLORIDE | PD-Rx Pharmaceuticals, Inc. | 2018-08-16 |
| 43063-0874-02 | 2 TABLET in 1 BOTTLE, PLASTIC (43063-874-02) | PROMETHAZINE HYDROCHLORIDE | PD-Rx Pharmaceuticals, Inc. | 2019-11-11 |
| 43063-0874-04 | 4 TABLET in 1 BOTTLE, PLASTIC (43063-874-04) | PROMETHAZINE HYDROCHLORIDE | PD-Rx Pharmaceuticals, Inc. | 2018-08-27 |
| 43063-0874-05 | 5 TABLET in 1 BOTTLE, PLASTIC (43063-874-05) | PROMETHAZINE HYDROCHLORIDE | PD-Rx Pharmaceuticals, Inc. | 2018-09-06 |
| 43063-0874-06 | 6 TABLET in 1 BOTTLE, PLASTIC (43063-874-06) | PROMETHAZINE HYDROCHLORIDE | PD-Rx Pharmaceuticals, Inc. | 2018-08-27 |
| 43063-0874-10 | 10 TABLET in 1 BOTTLE, PLASTIC (43063-874-10) | PROMETHAZINE HYDROCHLORIDE | PD-Rx Pharmaceuticals, Inc. | 2018-07-30 |
| 43063-0874-12 | 12 TABLET in 1 BOTTLE, PLASTIC (43063-874-12) | PROMETHAZINE HYDROCHLORIDE | PD-Rx Pharmaceuticals, Inc. | 2018-08-20 |
| 43063-0874-15 | 15 TABLET in 1 BOTTLE, PLASTIC (43063-874-15) | PROMETHAZINE HYDROCHLORIDE | PD-Rx Pharmaceuticals, Inc. | 2018-08-20 |
| 43063-0874-20 | 20 TABLET in 1 BOTTLE, PLASTIC (43063-874-20) | PROMETHAZINE HYDROCHLORIDE | PD-Rx Pharmaceuticals, Inc. | 2018-12-07 |
| 43063-0874-25 | 25 TABLET in 1 BOTTLE, PLASTIC (43063-874-25) | PROMETHAZINE HYDROCHLORIDE | PD-Rx Pharmaceuticals, Inc. | 2025-11-04 |
| 43063-0874-30 | 30 TABLET in 1 BOTTLE, PLASTIC (43063-874-30) | PROMETHAZINE HYDROCHLORIDE | PD-Rx Pharmaceuticals, Inc. | 2018-09-05 |
| 43063-0874-79 | 1 TABLET in 1 BOTTLE, PLASTIC (43063-874-79) | PROMETHAZINE HYDROCHLORIDE | PD-Rx Pharmaceuticals, Inc. | 2019-11-07 |
| 43063-0874-95 | 1000 TABLET in 1 BOTTLE, PLASTIC (43063-874-95) | PROMETHAZINE HYDROCHLORIDE | PD-Rx Pharmaceuticals, Inc. | 2018-08-17 |
| 50090-4452-00 | 5 TABLET in 1 BOTTLE (50090-4452-0) | PROMETHAZINE HYDROCHLORIDE | A-S Medication Solutions | 2019-08-05 |
| 50090-4453-00 | 12 TABLET in 1 BOTTLE (50090-4453-0) | PROMETHAZINE HYDROCHLORIDE | A-S Medication Solutions | 2019-08-05 |
| 50090-4453-01 | 10 TABLET in 1 BOTTLE (50090-4453-1) | PROMETHAZINE HYDROCHLORIDE | A-S Medication Solutions | 2019-08-05 |
| 50090-4453-05 | 60 TABLET in 1 BOTTLE (50090-4453-5) | PROMETHAZINE HYDROCHLORIDE | A-S Medication Solutions | 2019-08-05 |
| 50090-4453-06 | 20 TABLET in 1 BOTTLE (50090-4453-6) | PROMETHAZINE HYDROCHLORIDE | A-S Medication Solutions | 2019-08-05 |
| 50090-4453-09 | 30 TABLET in 1 BOTTLE (50090-4453-9) | PROMETHAZINE HYDROCHLORIDE | A-S Medication Solutions | 2019-08-05 |
| 50090-4608-00 | 90 TABLET in 1 BOTTLE (50090-4608-0) | PROMETHAZINE HYDROCHLORIDE | A-S Medication Solutions | 2019-10-15 |
| 50090-4750-00 | 12 TABLET in 1 BOTTLE (50090-4750-0) | PROMETHAZINE HYDROCHLORIDE | A-S Medication Solutions | 2019-11-22 |
| 50090-4811-00 | 5 TABLET in 1 BOTTLE (50090-4811-0) | Promethazine Hydrochloride | A-S Medication Solutions | 2019-12-27 |
| 50090-4812-00 | 90 TABLET in 1 BOTTLE (50090-4812-0) | Promethazine Hydrochloride | A-S Medication Solutions | 2019-12-27 |
| 50090-4813-00 | 12 TABLET in 1 BOTTLE (50090-4813-0) | Promethazine Hydrochloride | A-S Medication Solutions | 2019-12-27 |
| 50090-4813-01 | 10 TABLET in 1 BOTTLE (50090-4813-1) | Promethazine Hydrochloride | A-S Medication Solutions | 2019-12-27 |
| 50090-4813-05 | 60 TABLET in 1 BOTTLE (50090-4813-5) | Promethazine Hydrochloride | A-S Medication Solutions | 2019-12-27 |
| 50090-4813-06 | 20 TABLET in 1 BOTTLE (50090-4813-6) | Promethazine Hydrochloride | A-S Medication Solutions | 2019-12-27 |
Observed labelers:
ASCLEMED USA INC. (25) ·
Sportpharm LLC (25) ·
PD-Rx Pharmaceuticals, Inc. (24) ·
Proficient Rx LP (22) ·
Bryant Ranch Prepack (20) ·
A-S Medication Solutions (16)
· +20 more — this is the FDA-listed mapping footprint, not sales, inventory, availability, or market share.
🗃️ Sources & Limits
Atlas generation902fddb9-e9c1-4004-bf4c-dba4d51037c7
openFDA export observedJul 14, 2026
RxNorm release07/06/2026
Methodology2026-07-full-catalog-v1
- A shared RxCUI does not prove interchangeability. Products mapped to the same concept are not thereby equivalent or substitutable — equivalence is a separate, product-level determination.
- Listing here does not establish approval or coverage. Appearing in this snapshot is a data observation, not an FDA approval status or a payer coverage decision.
- Missing data never means zero. A silent dataset (no price, no billing code, no utilization) means no observation — not that the real-world value is zero.
- Counts describe the mapping footprint. Product, package, and labeler counts are the FDA-listed mapping footprint in this snapshot — not sales, inventory, availability, or market share.
This product uses publicly available data from the U.S. National Library of Medicine (NLM), National Institutes of Health, Department of Health and Human Services; NLM is not responsible for the product and does not endorse or recommend this or any other product.
Reference information about drug-concept identifiers and public regulatory data — not medical advice. Talk to your pharmacist or prescriber about your own medication.