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Codeine phosphate 2 MG/ML / phenylephrine hydrochloride 1 MG/ML / promethazine hydrochlori... — RxCUI 996757

Name: Codeine phosphate 2 MG/ML / phenylephrine hydrochloride 1 MG/ML / promethazine hydroc… (RxCUI 996757)
Creator: Brian Staiger, PharmD

RxNorm drug concept · Semantic clinical drug

RxCUI 996757 Semantic clinical drug · SCD ● Current RxNorm concept 1 FDA product 2 package NDCs Snapshot Jul 14, 2026

This page is curated, coded, and maintained by Dr. Brian Staiger, PharmD

Compiled from public NLM RxNorm and FDA (openFDA NDC directory) data sources. Editorial policy

What you’re looking at: the standardized identity of one medicine, as the U.S. drug-data system sees it. Below — every FDA-listed product, package code, price benchmark, and billing code that maps to it.

🗂️ Key Facts

RxCUI996757

Official nameCodeine phosphate 2 MG/ML / phenylephrine hydrochloride 1 MG/ML / promethazine hydrochloride 1.25 MG/ML Oral Solution

Concept typeSemantic clinical drug (SCD)

RxNorm statusCurrent RxNorm concept

Also known ascodeine phosphate 10 MG / phenylephrine hydrochloride 5 MG / promethazine hydrochloride 6.25 MG per 5 ML Oral Solution; codeine phosphate 10 MG / phenylephrine HCl 5 MG / promethazine HCl 6.25 MG in 5 mL Oral Solution

FDA products mapped1

Package NDCs mapped2

RxNorm release07/06/2026

Snapshot dataJul 14, 2026

📖 Skip the Codes — Read It in Plain English.

Our pharmacist-built guide to Phenylephrine: what it is, how it’s used, side effects, and interactions.

📗 Our plain-language guide HelloPharmacist

Yes, it's the same active ingredient, but used in very different ways depending on the form. The nasal spray delivers a tiny amount directly to the nasal lining to temporarily shri...
I see phenylephrine in nasal sprays at the pharmacy AND as an IV drug in the hospital — is it really the same medication?
You should check with your doctor first. Phenylephrine constricts blood vessels, which can raise blood pressure and put extra strain on the heart — even from a nasal spray. If you...
Can I use the nasal spray if I have high blood pressure or heart disease?

📖 Read our full Phenylephrine guide →

🕸️ Concept Web — How Codeine phosphate 2 MG/ML / phenylephrine hydroc... Connects

One RxCUI never lives alone. Follow the path from the raw ingredient down to the exact strength-and-form concepts FDA products carry — every stop is a real RxNorm concept with its own identifier. Hover or focus any chip for what it means.

This page's concept Codeine phosphate 2 MG/ML / phenylephrine hydrochloride 1 MG/ML / promethazine hydrochloride 1.25 MG/ML Oral Solution RxCUI 996757 Semantic clinical drug · SCD

Every web starts here: one RxCUI, one fixed meaning in the RxNorm vocabulary.

Ingredients 7

The active substance itself — no strength, form, or brand attached yet.
- Codeine 2670 IN
- Phenylephrine 8163 IN
- Promethazine 8745 IN
- Codeine / phenylephrine / promethazine 214449 MIN
- Codeine phosphate 2672 PIN
- Phenylephrine hydrochloride 8164 PIN
- Promethazine hydrochloride 142445 PIN
Dose forms 9

The ingredient poured into a form — tablet, solution, cream — still without one fixed strength.
- Codeine / phenylephrine / promethazine Oral Solution 376076 SCDF
- Codeine phosphate / phenylephrine hydrochloride / promethazine hydrochloride Oral Solution 2648406 SCDFP
- Codeine / phenylephrine / promethazine Oral Liquid Product 1154830 SCDG
- Codeine / phenylephrine / promethazine Oral Product 1154831 SCDG
- Codeine phosphate / phenylephrine hydrochloride / promethazine hydrochloride Oral Liquid Product 2662855 SCDGP
- Codeine phosphate / phenylephrine hydrochloride / promethazine hydrochloride Oral Product 2661553 SCDGP
- Oral Solution 316968 DF
- Oral Liquid Product 1151137 DFG
- +1 more in this family
Clinical & branded drugs 3

Ingredient + strength + dose form. These are the concepts real FDA products actually carry.
- Codeine phosphate 2 MG/ML 832866 SCDC
- Phenylephrine hydrochloride 1 MG/ML 996578 SCDC
- Promethazine hydrochloride 1.25 MG/ML 991457 SCDC

Showing up to 8 concepts per family — 18 of 19 stored related concepts drawn.

These are official RxNorm vocabulary relationships — how concepts name and organize the same medicine. They do not establish therapeutic equivalence or substitutability: two concepts appearing in one web is never a statement that products can be swapped.

🔀 Generic ⇄ Brand Crosswalk

The same medicine has an unbranded (generic) identity and one or more brand-name identities — each with its own RxCUI. This is a naming relationship in RxNorm, not a statement that any two products are substitutable.

Generic (Clinical) Concepts

Codeine phosphate 2 MG/ML SCDC · 832866
Phenylephrine hydrochloride 1 MG/ML SCDC · 996578
Promethazine hydrochloride 1.25 MG/ML SCDC · 991457
Codeine / phenylephrine / promethazine Oral Solution SCDF · 376076
Codeine phosphate / phenylephrine hydrochloride / promethazine hydrochloride Oral Solution SCDFP · 2648406
Codeine / phenylephrine / promethazine Oral Liquid Product SCDG · 1154830
Codeine / phenylephrine / promethazine Oral Product SCDG · 1154831
Codeine phosphate / phenylephrine hydrochloride / promethazine hydrochloride Oral Liquid Product SCDGP · 2662855
Codeine phosphate / phenylephrine hydrochloride / promethazine hydrochloride Oral Product SCDGP · 2661553

📦 FDA Products & Package NDCs

1 product · 2 package NDCs

2 package NDCs map to RxCUI 996757 in the current snapshot — up to 50 per page. Each linked NDC opens its full package page.

Package NDC	Package	Brand / generic name	Labeler	Marketing start
65162-0694-86	118 mL in 1 BOTTLE (65162-694-86)	Promethazine and Phenylephrine HCl, and Codeine Phosphate	Amneal Pharmaceuticals LLC	2013-11-01
65162-0694-90	473 mL in 1 BOTTLE (65162-694-90)	Promethazine and Phenylephrine HCl, and Codeine Phosphate	Amneal Pharmaceuticals LLC	2013-11-01

Observed labelers: Amneal Pharmaceuticals LLC (2) — this is the FDA-listed mapping footprint, not sales, inventory, availability, or market share.

🗃️ Sources & Limits

Atlas generation902fddb9-e9c1-4004-bf4c-dba4d51037c7

openFDA export observedJul 14, 2026

RxNorm release07/06/2026

Methodology2026-07-full-catalog-v1

A shared RxCUI does not prove interchangeability. Products mapped to the same concept are not thereby equivalent or substitutable — equivalence is a separate, product-level determination.
Listing here does not establish approval or coverage. Appearing in this snapshot is a data observation, not an FDA approval status or a payer coverage decision.
Missing data never means zero. A silent dataset (no price, no billing code, no utilization) means no observation — not that the real-world value is zero.
Counts describe the mapping footprint. Product, package, and labeler counts are the FDA-listed mapping footprint in this snapshot — not sales, inventory, availability, or market share.

This product uses publicly available data from the U.S. National Library of Medicine (NLM), National Institutes of Health, Department of Health and Human Services; NLM is not responsible for the product and does not endorse or recommend this or any other product.

Machine-readable JSON

Reference information about drug-concept identifiers and public regulatory data — not medical advice. Talk to your pharmacist or prescriber about your own medication.