Can You Take Amoxicillin With Entresto?

Answer

There is no known interaction between Entresto and amoxicillin. They are considered safe to take together.

I appreciate you reaching out! It's always a good idea to look into potential drug interactions, especially when drugs are being prescribed by two different providers.

Additionally, I imagine you are being prescribed amoxicillin by your dentist because you are at 'high risk' for infective endocarditis. Antibiotic prophylaxis is generally recommended for some individuals with certain cardiac conditions. This is a topic we've written about before (which can be found here).

With you likely being more at risk to complications due to your health condition, it's especially important that you look out for dangerous drug interactions.

As mentioned though, Entresto is considered safe with amoxicillin.

What Is Entresto?

Entresto contains two drugs, valsartan and sacubitril, and is usually used in combination with other medications to lower the risk of death and hospitalization in adults with certain types of heart failure.

Valsartan is in a class of medications called angiotensin II receptor antagonists and works by blocking the action of certain natural substances that tighten the blood vessels, allowing the blood to flow more smoothly and the heart to pump more efficiently.

Sacubitril is in a class of medications called neprilysin inhibitors and works to help control blood volume.

What Is Amoxicillin?

Amoxicillin is an 'aminopenicillin' used to treat certain infections caused by bacteria, such as pneumonia; bronchitis (infection of the airway tubes leading to the lungs); and infections of the ears, nose, throat, urinary tract, and skin.

Amoxicillin is in a class of medications called penicillin-like antibiotics and works by stopping the growth of bacteria.

Final Words

Thanks so much for reaching out and please do so again anytime!