Is Mucinex DM Safe If You Have High Blood Pressure?

In our latest question and answer, our pharmacist discusses the safety of taking Mucinex DM if you have high blood pressure (hypertension).

Question

I have high blood pressure. Is taking Mucinex DM ok?

Asked by Helen On Sep 11, 2022

Answered by
Medical Content Reviewed By HelloPharmacist Staff

Published Sep 12, 2022
Last updated Mar 28, 2024

Key points

  • Mucinex DM (guaifenesin; dextromethorphan) does not affect blood pressure and is considered safe to take in those diagnosed with high blood pressure.

Answer

Thanks so much for reaching out to us! Yes, Mucinex DM (guaifenesin; dextromethorphan) is safe to take if you have high blood pressure (hypertension). Neither drug contained in Mucinex DM affects blood pressure.

The Drugs In Mucinex DM Don't Affect Blood Pressure

As stated, Mucinex DM contains:

  • Guaifenesin
  • Dextromethorphan

Guaifenesin is an expectorant, which thins and loosens mucus secretions, making these secretions easier to expectorate. Dextromethorphan, the 'DM' component in Mucinex DM, is a cough suppressant and works by decreasing activity in the part of the brain that causes coughing.

Unlike some cold medications, guaifenesin and dextromethorphan are considered safe to take if you have high blood pressure.

The drug you want to avoid, or only take under the direction of your doctor if you have high blood pressure, is the nasal decongestant pseudoephedrine. Pseudoephedrine can blood pressure and can put individuals with pre-existing heart conditions more at risk for side effects.

Final Words

Thanks again for reaching out!

References

  • Effect of oral pseudoephedrine on blood pressure and heart rate: a meta-analysis, PubMed
  • Pseudoephedrine—Benefits and Risks, PubMed
  • Guaifenesin Monograph, PubChem
  • Dextromethorphan Monograph, PubChem

About the Pharmacist

Dr. Brian Staiger, PharmD

Dr. Brian has been practicing pharmacy for over 13 years and has wide-ranging experiences in many different areas of the profession. From retail, clinical, program development, and administrative responsibilities, he's your knowledgeable and go-to source for all your pharmacy and medication-related questions! Dr. Brian Staiger also has herbalist training and educational certificates in the field of medical ethnobotany. Feel free to send him an email at [email protected]! You can also connect with Dr. Brian Staiger on LinkedIn.

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