Maty's Organic Children's Nighttime Cough Syrup With Tylenol

In our latest question and answer, the pharmacist discusses whether it is safe to combine Maty's Organic Cough Syrup With Tylenol.

2 min read Updated Jun 2026 Read by 1,770 people
Maty's Organic Children's Nighttime Cough Syrup With Tylenol
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Daphne asked

Can my child use Maty's Organic Nighttime Cough Syrup with Tylenol?

Dec 29, 2022
The quick answer
  • Maty's Organic Children's Nighttime Cough Syrup is safe to take with Tylenol because there are no known interactions between them.
  • While nutmeg in the syrup may slightly decrease Tylenol levels in some people, this effect is not considered clinically significant.
A quick summary of Dr. Brian Staiger, PharmD's full answer below, condensed by AI from that answer only (not from any outside source). The pharmacist's answer is the source of record.
Medications in this answer — tap to explore

Answer

Thanks so much for contacting us! Maty's Organic Goodnight Cough Syrup is considered safe to take with Tylenol (acetaminophen). There are no known interactions between the two.

What Is In Maty's Organic Goodnight Cough Syrup?

Matys Childrens Goodnight Cough Syrup

Maty's Organic Children’s Goodnight Cough Syrup contains the following ingredients:

  • Organic Honey
  • Organic Olive Oil
  • Organic Chamomile Tea
  • Sea Salt
  • Organic Cinnamon
  • Organic Lemon Peel
  • Organic Lemon Balm Extract
  • Organic Clove Oil
  • Organic Nutmeg
  • Organic Cayenne Pepper
  • Organic Marjoram

Now, it can be very difficult at times to definitively determine whether or not natural or herbal ingredients interact with prescription or over-the-counter drugs simply due to the lack of available data.

Nevertheless, looking into all of the ingredients in this cough syrup, it doesn't appear as though there is anything to be concerned with in regard to interactions with Tylenol (acetaminophen).

There is some evidence that nutmeg may slightly decrease Tylenol (acetaminophen) concentrations in some individuals due to how it affects certain metabolizing enzymes, but it isn't thought to be clinically significant.

I checked several different drug and herbal references for all of the different ingredients in these products, and again, there is nothing to suggest any interactions.

You can feel safe combining Maty's Organic Goodnight Cough Syrup with Tylenol.

Final Words

I wanted to thank you again for reaching out and I hope your child starts to feel better.

References & sources
  1. Acetaminophen Monograph — PubChem
  2. Induction of rat hepatic cytochrome P450 enzymes by myristicin — PubMed
Glossary — Terms in This Answer
Acetaminophen
A common over-the-counter pain reliever and fever reducer, also known as Tylenol.
Interactions
When two or more substances affect each other's effectiveness or safety when taken together.
Herbal ingredients
Active substances derived from plants, herbs, or natural sources used for medicinal purposes.
Metabolizing enzymes
Proteins in the body that break down medications and other substances so they can be processed and eliminated.
Clinically significant
Important enough to cause noticeable effects on a patient's health or treatment outcome.
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Dr. Brian Staiger, PharmD
About the pharmacist

Dr. Brian Staiger, PharmD

Clinical Pharmacy

Doctor of Pharmacy, board certified clinical pharmacist (BCPS), American Herbalist Guild, Medication Therapy Management certified

Brian Staiger, PharmD, BCPS, is a licensed pharmacist with more than 13 years of experience across retail pharmacy, clinical pharmacy, medication safety, pharmacy program development, and healthcare administration. He is the founder of HelloPharmacist.com, where he helps patients...

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