Maty's Organic Children's Nighttime Cough Syrup With Tylenol
In our latest question and answer, the pharmacist discusses whether it is safe to combine Maty's Organic Cough Syrup With Tylenol.

Question
Can my child use Maty's Organic Nighttime Cough Syrup with Tylenol?

Answered by Dr. Brian Staiger, PharmD
Medical Content Reviewed By HelloPharmacist
Staff
Last updated Apr 10, 2025
Key points
- There is no known drug interaction between Maty's Organic Children's Goodnight Cough Syrup and Tylenol (acetaminophen).
Answer
Thanks so much for contacting us! Maty's Organic Goodnight Cough Syrup is considered safe to take with Tylenol (acetaminophen). There are no known interactions between the two.
What Is In Maty's Organic Goodnight Cough Syrup?
Maty's Organic Children’s Goodnight Cough Syrup contains the following ingredients:
- Organic Honey
- Organic Olive Oil
- Organic Chamomile Tea
- Sea Salt
- Organic Cinnamon
- Organic Lemon Peel
- Organic Lemon Balm Extract
- Organic Clove Oil
- Organic Nutmeg
- Organic Cayenne Pepper
- Organic Marjoram
Now, it can be very difficult at times to definitively determine whether or not natural or herbal ingredients interact with prescription or over-the-counter drugs simply due to the lack of available data.
Nevertheless, looking into all of the ingredients in this cough syrup, it doesn't appear as though there is anything to be concerned with in regard to interactions with Tylenol (acetaminophen).
There is some evidence that nutmeg may slightly decrease Tylenol (acetaminophen) concentrations in some individuals due to how it affects certain metabolizing enzymes, but it isn't thought to be clinically significant.
I checked several different drug and herbal references for all of the different ingredients in these products, and again, there is nothing to suggest any interactions.
You can feel safe combining Maty's Organic Goodnight Cough Syrup with Tylenol.
Final Words
I wanted to thank you again for reaching out and I hope your child starts to feel better.
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Dr. Brian Staiger, PharmD
- 1504 views