Taking Claritin With Mucinex

In our latest question and answer, the pharmacist discusses whether or not Claritin (loratadine) can be taken with Mucinex (guaifenesin).

Question

Is it ok to take Mucinex and Claritin together?

Asked by Chase On May 23, 2022

Answered by
Medical Content Reviewed By HelloPharmacist Staff

Published May 23, 2022
Last updated Apr 19, 2024

Key points

  • There is no drug interaction between Claritin (loratadine) and Mucinex (guaifenesin). They are safe to take together.

Yes, Mucinex (guaifenesin) and Claritin (loratadine) can be taken together as there is no interaction between the two medications.

I've written some additional information about both drugs below.

Taking Claritin And Mucinex Together

Mucinex (guaifenesin) is an expectorant that helps loosen and thin mucus to make a cough more productive.

There are several other products that guaifenesin is found in, in addition to Mucinex.

It can also be found in combination products like Mucinex-DM (which also contains an antitussive agent called dextromethorphan that helps control a cough) and DayQuil Severe.

Mucinex (guaifenesin) is generally a well-tolerated medication.

Some side effects that have been reported are dizziness, drowsiness, headache, rash, nausea, vomiting, and stomach pain. Mucinex (guaifenesin) also has no known drug interactions.

Claritin (loratadine) is a second-generation antihistamine that is used in the treatment of seasonal allergies and urticaria (itching due to hives).  

Second-generation antihistamines, like Claritin (loratadine), typically do not cause sedation or drowsiness.  

It too is also a generally well-tolerated medication.  The most common side effect reported is headache followed by drowsiness, fatigue, and stomach pain.  

Final Words

As stated above, taking Mucinex (guaifenesin) and Claritin (loratadine) together is fine and there are no known drug interactions between the two medications.

Thanks again for your question!

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References

About the Pharmacist

Dr. Brian Staiger, PharmD

Dr. Brian has been practicing pharmacy for over 13 years and has wide-ranging experiences in many different areas of the profession. From retail, clinical, program development, and administrative responsibilities, he's your knowledgeable and go-to source for all your pharmacy and medication-related questions! Dr. Brian Staiger also has herbalist training and educational certificates in the field of medical ethnobotany. Feel free to send him an email at [email protected]! You can also connect with Dr. Brian Staiger on LinkedIn.

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