Will GOLO Release Interfere With Drug Tests?

In our latest question and answer, our pharmacist discusses whether or not GOLO Release can cause problems on drug tests.

3 min read Updated Jun 2026 Read by 4,295 people
Will GOLO Release Interfere With Drug Tests?
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Jessica asked

I want to take GOLO diet pills but I want to make sure that I won't test positive on a drug test.

Jan 05, 2023
The quick answer
  • GOLO Release does not contain stimulant ingredients like caffeine or guarana that are more commonly associated with drug test issues. The herbal ingredients in GOLO Release have not been reported to cause positive results on drug tests. Dietary supplements are not regulated as strictly as drugs by the FDA, so there is a small possibility of unlabeled ingredients, which is why choosing trusted manufacturers is important.
A quick summary of Dr. Brian Staiger, PharmD's full answer below, condensed by AI from that answer only (not from any outside source). The pharmacist's answer is the source of record.

Answer

Thanks so much for reaching out! Having looked at all the ingredients in GOLO Release, it doesn't appear to contain any ingredients that have been reported to cause positive results on drug tests.

When it comes to dietary supplements intended to help support weight loss, they generally contain at least some type of stimulant, like caffeine, green tea extract, guarana, DMAA, etc... While stimulant-type ingredients are probably more likely to cause issues with a drug test, GOLO Release doesn't have any of those.

I'll list out the ingredients in the next section, but, on the surface, I don't see anything to be concerned about in GOLO that would cause a problem with drug tests.

I do want to say, however, that while the ingredients contained in GOLO on their own shouldn't cause any problems with drug tests for say, amphetamines, it's not uncommon that we see some dietary supplements contain unlabeled ingredients (and this is something the FDA does sometimes inspect and send warning letters out for).

Remember that dietary supplements aren't regulated by the FDA (Food and Drug Administration) the same way drugs are. I'm not suggesting that GOLO Release may contain some type of adulterated ingredient, just that you should always be prudent to utilize trusted companies and suppliers.

What Does GOLO Release Contain?

Golo Bottle With Supplement Facts

Golo contains several herbal and natural medicines, including:

I won't get into the details of all these different herbal ingredients, but they are all well-known and often utilized in weight loss products and products marketed toward individuals diagnosed with type II diabetes.

For example, berberine and banaba (note this is banaba, not banana) are purported to have antidiabetic effects by multiple mechanisms, such as lowering blood sugar or improving insulin resistance. If you do have specific questions about any of these, be sure to reach back out and ask one of the pharmacists.

Problems With Drug Tests?

As mentioned, there is nothing in GOLO Release that we would anticipate causing a problem on a drug test.

While we can never be 100% sure with dietary supplements due to how they are regulated, GOLO Release doesn't list any stimulant that many other weight loss supplements have, so I imagine it would be far less likely to cause any problems in that regard.

I will say, however, that most of the information we have regarding drug tests, and substances that could cause either false positives or false negatives, are other drugs, not herbal ingredients. There is far less data available for these ingredients so we may just not know if anything is particularly risky.

Final Words

Thanks again for reaching out and please do so again anytime.

References & sources
  1. Urine Drug Screening: Practical Guide for Clinicians — Mayo Clinic
Glossary — Terms in This Answer
Dietary supplements
Products containing vitamins, minerals, herbs, or other ingredients taken by mouth to supplement the diet and support health.
Stimulant
A substance that increases alertness and activity by speeding up brain and body functions.
Caffeine
A natural stimulant found in coffee, tea, and some other plants that increases energy and alertness.
FDA
The Food and Drug Administration, the U.S. government agency responsible for regulating food and drug safety.
Adulterated
Contaminated or containing unwanted substances that shouldn't be there.
Berberine
A natural compound found in certain plants that is studied for its potential effects on blood sugar and metabolism.
Antidiabetic
Having the ability to help lower blood sugar levels or improve how the body handles blood sugar.
Insulin resistance
A condition where the body's cells don't respond properly to insulin, making it harder to control blood sugar levels.
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Dr. Brian Staiger, PharmD
About the pharmacist

Dr. Brian Staiger, PharmD

Clinical Pharmacy

Doctor of Pharmacy, board certified clinical pharmacist (BCPS), American Herbalist Guild, Medication Therapy Management certified

Brian Staiger, PharmD, BCPS, is a licensed pharmacist with more than 13 years of experience across retail pharmacy, clinical pharmacy, medication safety, pharmacy program development, and healthcare administration. He is the founder of HelloPharmacist.com, where he helps patients...

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