Allopurinol Injection

Name: Allopurinol Injection Drug Interactions
Creator: Dr. Brian Staiger, PharmD, BCPS

26 interactions 333 cited references

Also sold as: Aloprim Aloprim® Zyloprim

About Allopurinol Injection

Allopurinol injection is used to treat high levels of uric acid (a natural substance that builds up in the blood as tumors break down) in people with certain types of cancer who are being treated with chemotherapy medications who cannot take oral allopurinol. Allopurinol is in a class of medications called xanthine oxi… Read the full Allopurinol Injection drug information page →

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jul 12, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Didanosine Fezolinetant Acenocoumarol Azathioprine Capecitabine Captopril

2 Contraindicated 18 Major 5 Moderate 1 Minor

All (26) Contraindicated (2) Major (18) Moderate (5) Minor (1)

Contraindicated

Allopurinol Injection Didanosine Videx® Increased serum concentrations of didanosine Details Allopurinol Injection Fezolinetant Increased fezolinetant exposure Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.