Anagrelide

434 interactions 313 cited references

Also sold as: Agrylin Agrylin®

About Anagrelide

Anagrelide is used to decrease the number of platelets (a type of blood cell that is needed to control bleeding) in the blood of patients who have a bone marrow disorder, in which the body makes too many of one or more types of blood cells, such as essential thrombocythemia (condition in which the body makes too many p… Read the full Anagrelide drug information page →

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 9, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Piperaquine Bepridil Mesoridazine Abrocitinib Pimozide Levoketoconazole

15 Contraindicated 376 Major 41 Moderate 2 Minor

All (434) Contraindicated (15) Major (376) Moderate (41) Minor (2)

Major

Anagrelide Dofetilide Tikosyn Increased risk of QT interval prolongation Details Anagrelide Dolasetron Anzemet Increased risk of QT interval prolongation Details Anagrelide Domperidone Increased risk of QT interval prolongation Details Anagrelide Donepezil Adlarity Increased risk of QT-interval prolongation and torsade de pointes Details Anagrelide Dordaviprone An increased risk of QT interval prolongation Details Anagrelide Doxepin Prudoxin Increased risk of QT interval prolongation Details Anagrelide Droperidol Increased risk of QT interval prolongation Details Anagrelide Droxicam An increased risk of bleeding Details Anagrelide Duloxetine An increased risk of bleeding Details Anagrelide Ebastine Increased risk of QT interval prolongation Details Anagrelide Edoxaban Savaysa Increased risk of bleeding Details Anagrelide Efavirenz An increased risk of QT interval prolongation Details Anagrelide Encorafenib Braftovi Increased risk of QT interval prolongation Details Anagrelide Enoxacin Increased anagrelide exposure Details Anagrelide Enoxaparin Lovenox Increased risk of bleeding Details Anagrelide Enoximone Increased bleeding risk; additive vasodilation; increased risk of tachycardia, palpitations, and heart failure Details Anagrelide Entrectinib Rozlytrek An increased risk of QT interval prolongation Details Anagrelide Eptifibatide Increased bleeding risk Details Anagrelide Eribulin Halaven Increased risk of QT interval prolongation Details Anagrelide Erythromycin Erythrocin Stearate Increased risk of QT interval prolongation Details Anagrelide Escitalopram Lexapro An increased risk of QT interval prolongation and an increased risk of bleeding Details Anagrelide Ethinyl Estradiol Increased anagrelide exposure Details Anagrelide Etodolac Lodine An increased risk of bleeding Details Anagrelide Etofenamate An increased risk of bleeding Details Anagrelide Etoricoxib An increased risk of bleeding Details Anagrelide Etrasimod Velsipity Increased risk of transient reduction in heart rate, AV conduction, QT interval prolongation and an increased risk of torsade de p... Details Anagrelide Famotidine Calmicid Increased risk of QT interval prolongation Details Anagrelide Felbamate Felbatol Increased risk of QT interval prolongation Details Anagrelide Felbinac An increased risk of bleeding Details Anagrelide Fenoprofen Fenopron An increased risk of bleeding Details Anagrelide Fepradinol An increased risk of bleeding Details Anagrelide Feprazone An increased risk of bleeding Details Anagrelide Fexinidazole An increased risk of QT interval prolongation Details Anagrelide Fingolimod Gilenya Increased risk of QT interval prolongation Details Anagrelide Flecainide Tambocor® Increased risk of QT interval prolongation Details Anagrelide Floctafenine An increased risk of bleeding Details Anagrelide Fluconazole Diflucan Increased risk of QT interval prolongation Details Anagrelide Flufenamic Acid An increased risk of bleeding Details Anagrelide Flumequine Increased anagrelide exposure Details Anagrelide Fluoxetine RECONCILE An increased risk of bleeding and an increased risk of QT interval prolongation Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.