Anagrelide

434 interactions 313 cited references

Also sold as: Agrylin Agrylin®

About Anagrelide

Anagrelide is used to decrease the number of platelets (a type of blood cell that is needed to control bleeding) in the blood of patients who have a bone marrow disorder, in which the body makes too many of one or more types of blood cells, such as essential thrombocythemia (condition in which the body makes too many p… Read the full Anagrelide drug information page →

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 9, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Piperaquine Bepridil Mesoridazine Abrocitinib Pimozide Levoketoconazole

15 Contraindicated 376 Major 41 Moderate 2 Minor

All (434) Contraindicated (15) Major (376) Moderate (41) Minor (2)

Major

Anagrelide Flurbiprofen Ansaid An increased risk of bleeding Details Anagrelide Fluvoxamine Increased anagrelide exposure and increased risk of bleeding Details Anagrelide Fondaparinux Arixtra Increased risk of bleeding Details Anagrelide Formoterol Perforomist Increased risk of QT interval prolongation Details Anagrelide Foscarnet Foscavir Increased risk of QT interval prolongation Details Anagrelide Fosfomycin Contepo An increased risk of QT interval prolongation Details Anagrelide Fosphenytoin Cerebyx Decreased anagrelide exposure; increased risk of QT interval prolongation Details Anagrelide Fostemsavir Rukobia Increased risk of torsade de pointes Details Anagrelide Galantamine Razadyne Increased risk of QT interval prolongation Details Anagrelide Gatifloxacin Zymaxid Increased anagrelide exposure and increased risk of QT interval prolongation Details Anagrelide Gemifloxacin Factive Increased anagrelide exposure and increased risk of QT interval prolongation Details Anagrelide Gepirone Exxua An increased risk of QT interval prolongation and cardiac arrhythmias Details Anagrelide Gepotidacin Blujepa An increased risk of QT interval prolongation Details Anagrelide Givinostat Duvyzat Increased risk of QT interval prolongation and torsade de pointes Details Anagrelide Glasdegib Daurismo Increased risk of QT interval prolongation Details Anagrelide Goserelin Increased risk of QT interval prolongation Details Anagrelide Granisetron Increased risk of QT interval prolongation Details Anagrelide Halofantrine Increased risk of QT interval prolongation Details Anagrelide Haloperidol Increased risk of QT interval prolongation Details Anagrelide Heparin Increased risk of bleeding Details Anagrelide Histrelin Supprelin Increased risk of QT interval prolongation Details Anagrelide Hydroquinidine Increased risk of QT interval prolongation Details Anagrelide Hydroxychloroquine Plaquenil Increased risk of QT interval prolongation Details Anagrelide Hydroxyzine An increased risk of QT interval prolongation Details Anagrelide Ibrutinib Imbruvica Increased risk of bleeding Details Anagrelide Ibuprofen Addaprin An increased risk of bleeding Details Anagrelide Ibutilide Corvert Increased risk of QT interval prolongation Details Anagrelide Iloperidone Fanapt Increased risk of QT interval prolongation Details Anagrelide Imipramine Increased risk of QT interval prolongation Details Anagrelide Inamrinone Increased bleeding risk; additive vasodilation; increased risk of tachycardia, palpitations, and heart failure Details Anagrelide Indomethacin Indocin An increased risk of bleeding Details Anagrelide Inotersen Increased risk of bleeding Details Anagrelide Inotuzumab Ozogamicin Besponsa Increased risk of QT interval prolongation Details Anagrelide Isoflurane Fluriso An increased risk of QT interval prolongation and torsade de pointes Details Anagrelide Itraconazole Sporanox Increased risk of QT interval prolongation Details Anagrelide Ivabradine Corlanor Increased risk of QT prolongation Details Anagrelide Ivosidenib Tibsovo An increased risk of QT interval prolongation Details Anagrelide Ketoconazole Extina An increased risk for QT interval prolongation Details Anagrelide Ketoprofen Actron® An increased risk of bleeding Details Anagrelide Ketorolac Acular An increased risk of bleeding Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.