Aripiprazole Injection

347 interactions 801 cited references
Also sold as: Abilify Abilify Maintena® Abilify® Aristad Initio® Aristada® Opipza
About Aripiprazole Injection

Aripiprazole extended-release injection (Abilify Maintena, Aristada, Aristada Initio) is used alone or in combination with other aripiprazole preparations to treat schizophrenia (a mental illness that causes disturbed or unusual thinking, loss of interest in life, and strong or inappropriate emotions). Aripiprazole ext… Read the full Aripiprazole Injection drug information page →

Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jul 12, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Mavorixafor Mesoridazine Metoclopramide Pimozide Piperaquine Posaconazole
20 Contraindicated 316 Major 11 Moderate
All (347) Contraindicated (20) Major (316) Moderate (11)

Major

Aripiprazole Injection Selpercatinib Retevmo Increased risk of QT interval prolongation Details Aripiprazole Injection Sertindole An increased risk of QT interval prolongation Details Aripiprazole Injection Sertraline Increased risk of QT interval prolongation and an increased CYP2D6 substrate exposure Details Aripiprazole Injection Sevoflurane Petrem An increased risk of QT interval prolongation Details Aripiprazole Injection Siponimod Mayzent An increased risk of QT interval prolongation Details Aripiprazole Injection Sodium Oxybate Lumryz An increased risk of CNS depression and clinically significant respiratory depression, obtundation, hypotension, profound sedation... Details Aripiprazole Injection Sodium Phosphate OsmoPrep An increased risk of QT interval prolongation Details Aripiprazole Injection Sodium Phosphate, Dibasic An increased risk of QT interval prolongation Details Aripiprazole Injection Sodium Phosphate, Monobasic An increased risk of QT interval prolongation Details Aripiprazole Injection Solifenacin Vesicare An increased risk of QT interval prolongation Details Aripiprazole Injection Sorafenib Nexavar An increased risk of QT interval prolongation Details Aripiprazole Injection Sotalol Betapace An increased risk of QT interval prolongation Details Aripiprazole Injection St John's Wort Reduced ARIPiprazole exposure Details Aripiprazole Injection Sufentanil Dsuvia Reduced pulmonary arterial pressure, increased risk for hypotension, profound sedation, respiratory depression, coma, and death Details Aripiprazole Injection Sulpiride An increased risk of QT interval prolongation Details Aripiprazole Injection Sultopride An increased risk of QT interval prolongation Details Aripiprazole Injection Sunitinib Sutent An increased risk of QT interval prolongation Details Aripiprazole Injection Tacrolimus Astagraf An increased risk of QT interval prolongation Details Aripiprazole Injection Taletrectinib Ibtrozi Increased risk of QT interval prolongation and torsade de pointes Details Aripiprazole Injection Tamoxifen Nolvadex® An increased risk of QT interval prolongation Details Aripiprazole Injection Tapentadol Nucynta An increased risk of respiratory and CNS depression Details Aripiprazole Injection Tazemetostat Tazverik Reduced CYP3A substrate exposure and reduced efficacy of CYP3A substrate Details Aripiprazole Injection Telaprevir Increased ARIPiprazole exposure and an increased risk of QT interval prolongation Details Aripiprazole Injection Telavancin Vibativ An increased risk of QT interval prolongation Details Aripiprazole Injection Telithromycin Increased ARIPiprazole exposure and an increased risk of QT interval prolongation Details Aripiprazole Injection Temazepam Restoril An increased risk of sedation and orthostatic hypotension Details Aripiprazole Injection Terbinafine Lamisil Increased ARIPiprazole exposure Details Aripiprazole Injection Tetrabenazine Xenazine An increased risk of QT interval prolongation Details Aripiprazole Injection Tetrazepam An increased risk of sedation and orthostatic hypotension Details Aripiprazole Injection Tolterodine Detrol An increased risk of QT interval prolongation Details Aripiprazole Injection Topiramate Eprontia An increased risk of CNS depression Details Aripiprazole Injection Toremifene Fareston An increased risk of QT interval prolongation Details Aripiprazole Injection Tramadol ConZip Increased risk of CNS depression Details Aripiprazole Injection Tranylcypromine Parnate An increased risk of CNS depression Details Aripiprazole Injection Trazodone Raldesy Increased risk of CNS depression and an increased risk of QT interval prolongation Details Aripiprazole Injection Triazolam Halcion An increased risk of sedation and orthostatic hypotension Details Aripiprazole Injection Triclabendazole Egaten An increased risk of QT interval prolongation Details Aripiprazole Injection Trimipramine An increased risk of QT interval prolongation Details Aripiprazole Injection Triptorelin Increased risk of QT interval prolongation Details Aripiprazole Injection Troleandomycin Increased ARIPiprazole exposure Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.