Aripiprazole Injection

347 interactions 801 cited references
Also sold as: Abilify Abilify Maintena® Abilify® Aristad Initio® Aristada® Opipza
About Aripiprazole Injection

Aripiprazole extended-release injection (Abilify Maintena, Aristada, Aristada Initio) is used alone or in combination with other aripiprazole preparations to treat schizophrenia (a mental illness that causes disturbed or unusual thinking, loss of interest in life, and strong or inappropriate emotions). Aripiprazole ext… Read the full Aripiprazole Injection drug information page →

Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jul 12, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Mavorixafor Mesoridazine Metoclopramide Pimozide Piperaquine Posaconazole
20 Contraindicated 316 Major 11 Moderate
All (347) Contraindicated (20) Major (316) Moderate (11)

Major

Aripiprazole Injection Tucatinib Tukysa Increased ARIPiprazole exposure Details Aripiprazole Injection Vandetanib Caprelsa An increased risk of QT interval prolongation Details Aripiprazole Injection Vardenafil Levitra An increased risk of QT interval prolongation Details Aripiprazole Injection Vemurafenib Zelboraf Increased risk of QT interval prolongation Details Aripiprazole Injection Venlafaxine Increased CYP2D6 substrate exposure and an increased risk of QT interval prolongation Details Aripiprazole Injection Vepdegestrant Veppanu An increased risk of QT interval prolongation and an increased risk of torsade de pointes, polymorphic ventricular tachycardia, ot... Details Aripiprazole Injection Vilanterol An increased risk of QT interval prolongation Details Aripiprazole Injection Vinflunine An increased risk of QT interval prolongation Details Aripiprazole Injection Voclosporin Lupkynis An increased risk of QT interval prolongation Details Aripiprazole Injection Voriconazole Vfend Increased ARIPiprazole exposure and an increased risk of QT interval prolongation Details Aripiprazole Injection Vorinostat Zolinza An increased risk of QT interval prolongation Details Aripiprazole Injection Ziftomenib Komzifti An increased risk of QT interval prolongation and torsade de pointes Details Aripiprazole Injection Zolpidem Ambien An increased risk of CNS depression, complex sleep behaviors and respiratory depression Details Aripiprazole Injection Zotepine An increased risk of QT interval prolongation Details Aripiprazole Injection Zuclopenthixol An increased risk of QT interval prolongation Details Aripiprazole Injection Zuranolone Zurzuvae An increased risk of CNS depression Details

Moderate

Aripiprazole Injection Brimonidine Alphagan An increased risk of CNS depression Details Aripiprazole Injection Carbachol Isopto Carbachol An increased risk of CNS depression Details Aripiprazole Injection Cholecalciferol Decreased concentration of aripiprazole Details Aripiprazole Injection Clonidine Duraclon An increased risk of sedation and somnolence Details Aripiprazole Injection Ergocalciferol Calcidol Decreased concentration of aripiprazole Details Aripiprazole Injection Ganaxolone Ztalmy An increased risk of somnolence and sedation Details Aripiprazole Injection Insulin Afrezza Reduced blood glucose lowering effect of insulin Details Aripiprazole Injection Insulin Lispro, Recombinant Admelog May decrease blood glucose lowering effect of insulin lispro Details Aripiprazole Injection Mavacamten Camzyos Reduced CYP3A4 substrate exposure and reduced efficacy of CYP3A4 substrate Details Aripiprazole Injection Rilzabrutinib Wayrilz Increased CYP3A substrate exposure and an increased risk of CYP3A substrate-related adverse reactions Details Aripiprazole Injection Tizanidine An increased risk of CNS depression and sedation Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.