Asenapine Transdermal Patch

377 interactions 1 explained in plain English 412 cited references

Also sold as: Secuado Secuado®

About Asenapine Transdermal Patch

Asenapine transdermal patches are used to treat the symptoms of schizophrenia (a mental illness that causes disturbed or unusual thinking, loss of interest in life, and strong or inappropriate emotions). Asenapine is in a class of medications called atypical antipsychotics. It works by changing the activity of certain… Read the full Asenapine Transdermal Patch drug information page →

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 8, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

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15 Contraindicated 276 Major 86 Moderate

All (377) Contraindicated (15) Major (276) Moderate (86)

Major

Asenapine Transdermal Patch Esketamine Spravato Increased risk of sedation Details Asenapine Transdermal Patch Etrasimod Velsipity Increased risk of transient reduction in heart rate, AV conduction, QT interval prolongation and an increased risk of torsade de p... Details Asenapine Transdermal Patch Famotidine Calmicid Increased risk of QT interval prolongation Details Asenapine Transdermal Patch Felbamate Felbatol Increased risk of QT interval prolongation Details Asenapine Transdermal Patch Fentanyl Increased risk of profound sedation, respiratory depression, hypotension, coma and death Details Asenapine Transdermal Patch Fexinidazole An increased risk of QT interval prolongation Details Asenapine Transdermal Patch Fingolimod Gilenya Increased risk of QT interval prolongation Details Asenapine Transdermal Patch Flecainide Tambocor® Increased flecainide exposure, an increased asenapine exposure, an increased risk of QT interval prolongation and an increased ris... Details Asenapine Transdermal Patch Flibanserin Addyi Increased risk of CNS depression Details Asenapine Transdermal Patch Fluconazole Diflucan Increased risk of QT interval prolongation Details Asenapine Transdermal Patch Fluoxetine RECONCILE Increased FLUoxetine exposure, an increased asenapine exposure and an increased risk of QT interval prolongation Details Asenapine Transdermal Patch Fluvoxamine Increased asenapine exposure and an increased fluvoxaMINE exposure Details Asenapine Transdermal Patch Formoterol Perforomist Increased risk of QT interval prolongation and an increased risk of cardiovascular adverse effects Details Asenapine Transdermal Patch Foscarbidopa An increased risk of CNS depression Details Asenapine Transdermal Patch Foscarnet Foscavir Increased risk of QT interval prolongation Details Asenapine Transdermal Patch Fosfomycin Contepo An increased risk of QT interval prolongation Details Asenapine Transdermal Patch Foslevodopa An increased risk of CNS depression Details Asenapine Transdermal Patch Fosphenytoin Cerebyx An increased risk of QT interval prolongation Details Asenapine Transdermal Patch Fostemsavir Rukobia Increased risk of torsade de pointes Details Asenapine Transdermal Patch Gabapentin Gabarone An increased risk of respiratory depression and sedation Details Asenapine Transdermal Patch Gabapentin Enacarbil Horizant An increased risk of respiratory depression Details Asenapine Transdermal Patch Galantamine Razadyne Increased risk of QT interval prolongation Details Asenapine Transdermal Patch Gatifloxacin Zymaxid Increased risk of QT interval prolongation Details Asenapine Transdermal Patch Gefitinib Iressa Increased exposure of CYP2D6 substrate and inhibitor and an increased asenapine exposure Details Asenapine Transdermal Patch Gemifloxacin Factive Increased risk of QT interval prolongation Details Asenapine Transdermal Patch Gepirone Exxua An increased risk of QT interval prolongation and cardiac arrhythmias Details Asenapine Transdermal Patch Gepotidacin Blujepa An increased risk of QT interval prolongation Details Asenapine Transdermal Patch Givinostat Duvyzat Increased risk of QT interval prolongation and torsade de pointes Details Asenapine Transdermal Patch Glasdegib Daurismo Increased risk of QT interval prolongation Details Asenapine Transdermal Patch Goserelin Increased risk of QT interval prolongation Details Asenapine Transdermal Patch Granisetron Increased risk of QT interval prolongation Details Asenapine Transdermal Patch Halofantrine Increased risk of QT interval prolongation Details Asenapine Transdermal Patch Haloperidol Increased haloperidol exposure, an increased risk of haloperidol-related adverse events, an increased risk of CNS depression and i... Details Asenapine Transdermal Patch Histrelin Supprelin Increased risk of QT interval prolongation Details Asenapine Transdermal Patch Hydrocodone Hysingla Increased risk of respiratory and CNS depression Details Asenapine Transdermal Patch Hydromorphone Dilaudid Increased risk of respiratory and CNS depression Details Asenapine Transdermal Patch Hydroquinidine Increased risk of QT interval prolongation Details Asenapine Transdermal Patch Hydroxychloroquine Plaquenil Increased risk of QT interval prolongation Details Asenapine Transdermal Patch Hydroxyzine An increased risk of QT interval prolongation Details Asenapine Transdermal Patch Ibutilide Corvert Increased risk of QT interval prolongation Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.